| Online-Ressource |
Verfasst von: | Müller-Christmann, Christine [VerfasserIn]  |
| Hofmann, Maja [VerfasserIn]  |
| Jagoda, Agata [VerfasserIn]  |
| Spaenkuch, Iris [VerfasserIn]  |
| Forschner, Andrea [VerfasserIn]  |
| Tampouri, Ioanna [VerfasserIn]  |
| Lomberg, Diana [VerfasserIn]  |
| Leupold, Dieter [VerfasserIn]  |
| Garbe, Claus [VerfasserIn]  |
| Hänßle, Holger [VerfasserIn]  |
Titel: | Study protocol for a prospective, non-controlled, multicentre clinical study to evaluate the diagnostic accuracy of a stepwise two-photon excited melanin fluorescence in pigmented lesions suspicious for melanoma (FLIMMA study) |
Verf.angabe: | Christine Fink, Maja Hofmann, Agata Jagoda, Iris Spaenkuch, Andrea Forschner, Ioanna Tampouri, Diana Lomberg, Dieter Leupold, Claus Garbe, Holger A. Haenssle |
E-Jahr: | 2016 |
Jahr: | 19 December 2016 |
Umfang: | 4 S. |
Fussnoten: | Gesehen am 18.05.2020 |
Titel Quelle: | Enthalten in: BMJ open |
Ort Quelle: | London : BMJ Publishing Group, 2011 |
Jahr Quelle: | 2016 |
Band/Heft Quelle: | 6(2016,12) Artikel-Nummer e012730, 4 Seiten |
ISSN Quelle: | 2044-6055 |
Abstract: | Introduction Non-invasive, nanosecond, stepwise two-photon laser excitation of skin tissue was shown to induce melanin fluorescence spectra that allow for the differentiation of melanocytic nevi from cutaneous melanoma. - Methods and analysis This prospective, non-controlled, multicentre clinical study is performed to evaluate the diagnostic performance of the stepwise two-photon excited melanin fluorescence in the detection of cutaneous melanoma. The comparator will be the histopathological diagnosis. A total of 620 pigmented skin lesions suspicious for melanoma and intended for excision will be enrolled. - Ethics and dissemination Ethics approval was provided by the local ethics committees of the medical faculties of the University of Tuebingen, Heidelberg and Berlin. - Study registration The FLIMMA study NCT02425475. |
DOI: | doi:10.1136/bmjopen-2016-012730 |
URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
Volltext ; Verlag: https://doi.org/10.1136/bmjopen-2016-012730 |
| Volltext: https://bmjopen.bmj.com/content/6/12/e012730 |
| DOI: https://doi.org/10.1136/bmjopen-2016-012730 |
Datenträger: | Online-Ressource |
Sprache: | eng |
Sach-SW: | Diagnostic |
| Magnosco dermatofluoroscope |
| Melanin fluorescence |
| Melanoma |
| Two step photon excitation |
K10plus-PPN: | 1698450974 |
Verknüpfungen: | → Zeitschrift |
Study protocol for a prospective, non-controlled, multicentre clinical study to evaluate the diagnostic accuracy of a stepwise two-photon excited melanin fluorescence in pigmented lesions suspicious for melanoma (FLIMMA study) / Müller-Christmann, Christine [VerfasserIn]; 19 December 2016 (Online-Ressource)