MR-guided proton therapy

• Verfasst von: Hoffmann, Aswin [VerfasserIn]
• Verfasst von: Seco, Joao [VerfasserIn]
• Verfasst von: Jäkel, Oliver [VerfasserIn]
• Titel: MR-guided proton therapy
• Titelzusatz: a review and a preview
• Verf.angabe: Aswin Hoffmann, Bradley Oborn, Maryam Moteabbed, Susu Yan, Thomas Bortfeld, Antje Knopf, Herman Fuchs, Dietmar Georg, Joao Seco, Maria Francesca Spadea, Oliver Jäkel, Christopher Kurz and Katia Parodi
• E-Jahr: 2020
• Jahr: 29 May 2020
• Umfang: 13 S.
• Fussnoten: Gesehen am 26.10.2020
• Titel Quelle: Enthalten in: Radiation oncology
• Ort Quelle: London : BioMed Central, 2006
• Jahr Quelle: 2020
• Band/Heft Quelle: 15(2020) Artikel-Nummer 129, 13 Seiten
• ISSN Quelle: 1748-717X
• DOI: doi:10.1186/s13014-020-01571-x
• Datenträger: Online-Ressource
• Sprache: eng
• K10plus-PPN: 1736621971

Abstract

The targeting accuracy of proton therapy (PT) for moving soft-tissue tumours is expected to greatly improve by real-time magnetic resonance imaging (MRI) guidance. The integration of MRI and PT at the treatment isocenter would offer the opportunity of combining the unparalleled soft-tissue contrast and real-time imaging capabilities of MRI with the most conformal dose distribution and best dose steering capability provided by modern PT. However, hybrid systems for MR-integrated PT (MRiPT) have not been realized so far due to a number of hitherto open technological challenges. In recent years, various research groups have started addressing these challenges and exploring the technical feasibility and clinical potential of MRiPT. The aim of this contribution is to review the different aspects of MRiPT, to report on the status quo and to identify important future research topics.