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| Verfasst von: | Jaramillo Segura, Sonia [VerfasserIn]  |
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| | Hennemann, Hannah Mai [VerfasserIn] |
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| | Horak, Peter [VerfasserIn] |
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| | Teleanu, Maria-Veronica [VerfasserIn] |
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| | Heilig, Christoph E. [VerfasserIn] |
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| | Hutter, Barbara [VerfasserIn] |
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| | Stenzinger, Albrecht [VerfasserIn] |
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| | Glimm, Hanno [VerfasserIn] |
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| | Goeppert, Benjamin [VerfasserIn] |
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| | Müller-Tidow, Carsten [VerfasserIn] |
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| | Fröhling, Stefan [VerfasserIn] |
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| | Schönland, Stefan [VerfasserIn] |
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| | Schlenk, Richard Friedrich [VerfasserIn] |
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| Titel: | Ruxolitinib is effective in the treatment of a patient with refractory T-ALL |
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| Verf.angabe: | Sonia Jaramillo, Hannah Hennemann, Peter Horak, Veronica Teleanu, Christoph E. Heilig, Barbara Hutter, Albrecht Stenzinger, Hanno Glimm, Benjamin Goeppert, Carsten Müller-Tidow, Stefan Fröhling, Stefan Schönland, Richard F. Schlenk |
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| Jahr: | 2021 |
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| Umfang: | 4 S. |
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| Fussnoten: | First published: 04 December 2020 ; Gesehen am 07.09.2021 |
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| Titel Quelle: | Enthalten in: eJHaem |
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| Ort Quelle: | Hoboken, NJ : Wiley, 2020 |
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| Jahr Quelle: | 2021 |
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| Band/Heft Quelle: | 2(2021), 1, Seite 139-142 |
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| ISSN Quelle: | 2688-6146 |
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| Abstract: | T-cell acute lymphoblastic leukemia (T-ALL) is a rare, aggressive T-cell malignancy. Chemotherapy alone cures only 25-45% of the cases, thus, novel treatment agents and strategies are urgently needed. We assessed the efficacy of ruxolitinib in a patient with a cutaneous relapse after allogeneic blood cell transplantation of a refractory T-ALL with a Janus kinase 3 (JAK3) mutation. In this case report, we were able to show the potential benefit of the JAK inhibitor ruxolitinib in JAK3-mutated refractory T-ALL and emphasize the importance of integrating molecular markers in current treatment decision making for patients with T-ALL. |
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| DOI: | doi:10.1002/jha2.143 |
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| URL: | kostenfrei: Volltext ; Verlag: https://doi.org/10.1002/jha2.143 |
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| | kostenfrei: Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/jha2.143 |
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| | DOI: https://doi.org/10.1002/jha2.143 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| K10plus-PPN: | 1769525068 |
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| Verknüpfungen: | → Zeitschrift |
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| Lokale URL UB: |  Zum Volltext |
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Ruxolitinib is effective in the treatment of a patient with refractory T-ALL / Jaramillo Segura, Sonia [VerfasserIn]; 2021 (Online-Ressource)
