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| Verfasst von: | Valent, Peter [VerfasserIn]  |
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| | Hartmann, Karin [VerfasserIn] |
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| | Bonadonna, Patrizia [VerfasserIn] |
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| | Gülen, Theo [VerfasserIn] |
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| | Brockow, Knut [VerfasserIn] |
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| | Alvarez-Twose, Ivan [VerfasserIn] |
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| | Hermine, Olivier [VerfasserIn] |
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| | Niedoszytko, Marek [VerfasserIn] |
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| | Carter, Melody C. [VerfasserIn] |
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| | Hoermann, Gregor [VerfasserIn] |
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| | Butterfield, Joseph H. [VerfasserIn] |
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| | Lyons, Jonathan J. [VerfasserIn] |
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| | Sperr, Wolfgang R. [VerfasserIn] |
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| | Greiner, Georg [VerfasserIn] |
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| | Sotlar, Karl [VerfasserIn] |
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| | Kluin-Nelemans, Hanneke C. [VerfasserIn] |
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| | Schwaab, Juliana [VerfasserIn] |
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| | Lange, Magdalena [VerfasserIn] |
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| | George, Tracy I. [VerfasserIn] |
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| | Siebenhaar, Frank [VerfasserIn] |
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| | Broesby-Olsen, Sigurd [VerfasserIn] |
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| | Jawhar, Mohamad [VerfasserIn] |
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| | Nedoszytko, Boguslaw [VerfasserIn] |
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| | Castells, Mariana [VerfasserIn] |
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| | Orfao, Alberto [VerfasserIn] |
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| | Gotlib, Jason [VerfasserIn] |
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| | Reiter, Andreas [VerfasserIn] |
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| | Horny, Hans-Peter [VerfasserIn] |
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| | Triggiani, Massimo [VerfasserIn] |
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| | Arock, Michel [VerfasserIn] |
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| | Metcalfe, Dean D. [VerfasserIn] |
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| | Akin, Cem [VerfasserIn] |
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| Titel: | Global classification of mast cell activation disorders: an ICD-10-CM-adjusted proposal of the ECNM-AIM consortium |
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| Titelzusatz: | clinical commentary review |
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| Verf.angabe: | Peter Valent, Karin Hartmann, Patrizia Bonadonna, Theo Gülen, Knut Brockow, Ivan Alvarez-Twose, Olivier Hermine, Marek Niedoszytko, Melody C. Carter, Gregor Hoermann, Joseph H. Butterfield, Jonathan J. Lyons, Wolfgang R. Sperr, Georg Greiner, Karl Sotlar, Hanneke C. Kluin-Nelemans, Juliana Schwaab, Magdalena Lange, Tracy I. George, Frank Siebenhaar, Sigurd Broesby-Olsen, Mohamad Jawhar, Boguslaw Nedoszytko, Mariana Castells, Alberto Orfao, Jason Gotlib, Andreas Reiter, Hans-Peter Horny, Massimo Triggiani, Michel Arock, Dean D. Metcalfe, and Cem Akin |
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| E-Jahr: | 2022 |
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| Jahr: | August 2022 |
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| Umfang: | 10 S. |
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| Fussnoten: | Online verfügbar: 5 May 2022, Artikelversion: 9 August 2022 ; Gesehen am 07.11.2023 |
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| Titel Quelle: | Enthalten in: The journal of allergy and clinical immunology. In practice |
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| Ort Quelle: | Amsterdam [u.a.] : Elsevier, 2013 |
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| Jahr Quelle: | 2022 |
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| Band/Heft Quelle: | 10(2022), 8 vom: Aug., Seite 1941-1950 |
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| ISSN Quelle: | 2213-2201 |
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| Abstract: | Mast cell activation (MCA) is common and occurs in a number of pathologic conditions, including IgE-dependent and independent allergic reactions, atopic disorders, autoimmune processes, and mastocytosis. In a subset of patients, no underlying disease and no known trigger of MCA are found. When the symptoms are severe, systemic, and recurrent, and accompanied by a diagnostic increase in the serum tryptase level or other mast cell mediators, an MCA syndrome (MCAS) may be diagnosed. In these patients, the symptoms typically respond to drugs suppressing MCA, mediator production in mast cells, or mediator effects. In each case, diagnostic consensus criteria must be fulfilled to diagnose MCAS. In other patients, MCA may be local, less severe, or less acute, or may be suspected but not confirmed, so that the diagnostic criteria of MCAS are not fulfilled. In these patients, it may be difficult to prove MCA, for example, by measuring multiple mast cell mediators or basophil activation, the latter as a surrogate of IgE-dependent hypersensitivity. However, validated diagnostic criteria for implicating suspected MCA behind such conditions are lacking, even if some of these conditions have recently been assigned to an International Classification of Diseases-10-Clinical Modification code (ICD-10-CM). In this article, we discuss diagnostic features and criteria and propose a ICD-10-CM-adjusted classification for disorders associated with MCA, herein referred to as MCA disorders (MCADs), with special emphasis on the delineation between confirmed MCAS, MCAD not fulfilling MCAS criteria, and suspected MCAD that is not present. In addition, we discuss the discrimination between overt MCAD and predisposing conditions, such as atopic states, mastocytosis, and hereditary alpha tryptasemia. |
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| DOI: | doi:10.1016/j.jaip.2022.05.007 |
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| URL: | Bitte beachten Sie: Dies ist ein Bibliographieeintrag. Ein Volltextzugriff für Mitglieder der Universität besteht hier nur, falls für die entsprechende Zeitschrift/den entsprechenden Sammelband ein Abonnement besteht oder es sich um einen OpenAccess-Titel handelt.
kostenfrei: Volltext: https://doi.org/10.1016/j.jaip.2022.05.007 |
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| | kostenfrei: Volltext: https://www.sciencedirect.com/science/article/pii/S2213219822004937 |
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| | DOI: https://doi.org/10.1016/j.jaip.2022.05.007 |
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| Datenträger: | Online-Ressource |
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| Sprache: | eng |
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| Sach-SW: | Diagnostic criteria |
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| | HαT |
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| | Mast cell activation |
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| | Mastocytosis |
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| | MCAS |
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| K10plus-PPN: | 1869490711 |
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| Verknüpfungen: | → Zeitschrift |
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Global classification of mast cell activation disorders: an ICD-10-CM-adjusted proposal of the ECNM-AIM consortium / Valent, Peter [VerfasserIn]; August 2022 (Online-Ressource)
