Characterization of Austrian severe asthma patients

• Verfasst von: Renner, Andreas [VerfasserIn]
• Verfasst von: Stoshikj, Slagjana [VerfasserIn]
• Verfasst von: Pohl, Wolfgang [VerfasserIn]
• Verfasst von: Bal, Christina [VerfasserIn]
• Verfasst von: Reisinger, Matthias [VerfasserIn]
• Verfasst von: Löffler-Ragg, Judith [VerfasserIn]
• Verfasst von: Zacharasiewicz, Angela [VerfasserIn]
• Verfasst von: Buhl, Roland [VerfasserIn]
• Verfasst von: Hamelmann, Eckard [VerfasserIn]
• Verfasst von: Taube, Christian [VerfasserIn]
• Verfasst von: Korn, Stephanie [VerfasserIn]
• Verfasst von: Idzko, Marco [VerfasserIn]
• Titel: Characterization of Austrian severe asthma patients
• Verf.angabe: Andreas Renner, Slagjana Stoshikj, Wolfgang Pohl, Christina Bal, Matthias Reisinger, Judith Löffler-Ragg, Angela Zacharasiewicz, Roland Buhl, Eckard Hamelmann, Christian Taube, Stephanie Korn, Marco Idzko
• E-Jahr: 2023
• Jahr: 10 October 2023
• Umfang: 8 S.
• Illustrationen: Diagramme
• Fussnoten: Gesehen am 18.03.2024
• Titel Quelle: Enthalten in: Respiratory medicine
• Ort Quelle: Burlington, Mass. : Harcourt, 1999
• Jahr Quelle: 2023
• Band/Heft Quelle: 219(2023) vom: Nov./Dez., Artikel-ID 107427, Seite 1-8
• ISSN Quelle: 1532-3064
• DOI: doi:10.1016/j.rmed.2023.107427
• Datenträger: Online-Ressource
• Sprache: eng
• Sach-SW: Asthma
• Sach-SW: Asthma control
• Sach-SW: Biologics
• Sach-SW: Registry data
• Sach-SW: Severe asthma
• Sach-SW: Type-2-inflammation
• K10plus-PPN: 1883657008

Abstract

Introduction - The Severe Asthma Registry, founded by German Asthma Net (GAN) in 2011, is a prospective registry recording clinical parameters from participating centers in Germany, Austria and Switzerland. This article presents the baseline characteristics of severe asthma patients from Austrian centers. - Methods - We analyzed the baseline visit data of all patients recruited to the GAN Severe Asthma Registry from participating Austrian centers. - Results - Baseline visit data were available for 214 Austrian severe asthma patients from 6 Austrian centers from 2013 to 2022. Mean age was 53.7 years. Mean BMI was 26.4 kg/m2. More than a third (37.4%) of all patients had daily daytime asthma symptoms at baseline and had to use their reliever medication at least once per day. Forty-one percent of patients were classified as uncontrolled according to GINA and 24.8% as partially controlled at baseline visit. The median annual exacerbation frequency was 3 in the previous 12 months. At the time of baseline visit, 23.4% of all patients had regular treatment with oral corticosteroids. Furthermore, 23.9% had received any severe asthma monoclonal antibody prior to the baseline visit. There were no notable differences in baseline characteristics between patients categorized by smoking history or measurable type 2 inflammation. - Conclusions - This study provides the first multi-center characterization of Austrian severe asthma patients. Patients in this cohort had better asthma control and less frequent exacerbations compared to most international registries.