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Verfasst von:Beijer-Klippel, Annelie [VerfasserIn]   i
 Schick, Anita [VerfasserIn]   i
 Myin-Germeys, Inez [VerfasserIn]   i
 Rauschenberg, Christian [VerfasserIn]   i
 Vaessen, Thomas [VerfasserIn]   i
 Reininghaus, Ulrich [VerfasserIn]   i
Titel:Modelling the temporal interplay between stress and affective disturbances in pathways to psychosis
Titelzusatz:an experience sampling study
Verf.angabe:Annelie Klippel, Anita Schick, Inez Myin-Germeys, Christian Rauschenberg, Thomas Vaessen and Ulrich Reininghaus
Jahr:2022
Umfang:10 S.
Fussnoten:"First published online: 8 March 2021".- S. 2776 ; Gesehen am 20.06.2024
Titel Quelle:Enthalten in: Psychological medicine
Ort Quelle:Cambridge : Cambridge University Press, 1970
Jahr Quelle:2022
Band/Heft Quelle:52(2022), 13, Seite 2776-2785
ISSN Quelle:1469-8978
Abstract:BackgroundOne putative psychological mechanism through which momentary stress impacts on psychosis in individuals with increased liability to the disorder is via affective disturbance. However, to date, this has not been systematically tested. We aimed to investigate whether (i) cross-sectional and temporal effects of momentary stress on psychotic experiences via affective disturbance, and (ii) the reverse pathway of psychotic experiences on stress via affective disturbance were modified by familial liability to psychosis.MethodsThe Experience Sampling Method was used in a pooled data set of six studies with three groups of 245 individuals with psychotic disorder, 165 unaffected first-degree relatives, and 244 healthy control individuals to index familial liability. Multilevel moderated mediation models were fitted to investigate indirect effects across groups cross-sectionally and multilevel cross-lagged panel models to investigate temporal effects in the proposed pathways across two measurement occasions.ResultsEvidence on indirect effects from cross-sectional models indicated that, in all three groups, effects of stress on psychotic experiences were mediated by negative affect and, vice versa, effects of psychotic experiences on stress were mediated by negative affect, with all indirect effects being weakest in relatives. Longitudinal modelling of data provided no evidence of temporal priority of stress in exerting its indirect effects on psychotic experiences via affective disturbance or, vice versa.ConclusionsOur findings tentatively suggest a rapid vicious cycle of stress impacting psychotic experiences via affective disturbances, which does, however, not seem to be consistently modified by familial liability to psychosis.
DOI:doi:10.1017/S0033291720004894
URL:kostenfrei: Volltext: https://doi.org/10.1017/S0033291720004894
 kostenfrei: Volltext: https://www.cambridge.org/core/journals/psychological-medicine/article/modelling-the-temporal-interplay-between-stress-a ...
 DOI: https://doi.org/10.1017/S0033291720004894
Datenträger:Online-Ressource
Sprache:eng
Sach-SW:affective disturbance
 Ecological Momentary Assessment
 first-degree
 minor daily stress
 psychosis
 psychotic experiences
 relatives
K10plus-PPN:1891956213
Verknüpfungen:→ Zeitschrift
 
 
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