
Uhl, Philipp Dr. rer. nat.Universität HeidelbergHeidelberg
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- Haefeli, Walter E. (11)
- Domhan, Cornelius (10)
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Publications in heiBIB 
- Hammer, Maximilian: Early silicone oil opacification in the absence of emulsification is caused by an increased level of silicone dioxide / Maximilian Hammer, Leoni Britz, Manuel Ben Böhmann, Lorenz Herbster, Marcel Muuss, Jonathan Herth, S… , March 2025. - 10 S.
In: Retina, ISSN 1539-2864. 45(2025), 3 vom: März, Seite 491-500
DOI: 10.1097/IAE.0000000000004324
- Werner, Julia: Conjugation of polycationic peptides extends the efficacy spectrum of β-lactam antibiotics / Julia Werner, Florian Umstätter, Manuel B. Böhmann, Hannah Müller, Barbro Beijer, Tobias Hertlein, L… , December 26, 2024. - 12 S. : Illustrationen
In: Advanced science, ISSN 2198-3844. 11(2024), 48, Artikel-ID 2411406, Seite 1-12
DOI: 10.1002/advs.202411406
- Hammer, Maximilian: Quantification of straylight induced by silicone oil adherent to intraocular lenses of different materials / Maximilian Hammer, Leoni Britz, Sonja Schickhardt, Ingo Lieberwirth, Donald Munro, Philipp Uhl, Alex… , 2024. - 7 S.
In: American journal of ophthalmology, ISSN 1879-1891. 262(2024) vom: Juni, Seite 192-198
DOI: 10.1016/j.ajo.2023.11.018
- Wohlfart, Sabrina: Exposure to silicone oil endotamponades induces VEGF antibody aggregation and loss of functionality / Sabrina Wohlfart, Jonathan Herth, Manuel Ben Böhmann, Giulia Pander, Lorenz Herbster, Walter Mier, G… , November 2024. - 9 S. : Illustrationen
In: Investigative ophthalmology & visual science, ISSN 1552-5783. 65(2024), 13 vom: Nov., Artikel-ID 56, Seite 1-9
DOI: 10.1167/iovs.65.13.56
- Werner, Julia: Oral delivery of the vancomycin derivative FU002 by a surface-modified liposomal nanocarrier / Julia Werner, Florian Umstätter, Tobias Hertlein, Eric Mühlberg, Barbro Beijer, Sabrina Wohlfart, St… , June 1, 2024. - 11 S. : Illustrationen
In: Advanced healthcare materials, ISSN 2192-2659. 13(2024), 14 vom: Juli, Artikel-ID 2303654, Seite 1-11
DOI: 10.1002/adhm.202303654
- Werner, Julia: Improved pharmacokinetics and enhanced efficacy of the vancomycin derivative FU002 using a liposomal nanocarrier / Julia Werner, MSc, Florian Umstätter, PhD, Tobias Hertlein, PhD, Barbro Beijer, PhD, Christian Kleis… , February 2024. - 8 S. : Illustrationen
In: Nanomedicine, ISSN 1549-9642. 56(2024) vom: Feb., Artikel-ID 102731, Seite 1-8
DOI: 10.1016/j.nano.2023.102731
- Hartl, Natascha Verena: ApoE-functionalization of nanoparticles for targeted brain delivery : a feasible method for polyplexes? / Natascha Hartl, Bettina Gabold, Philipp Uhl, Adrian Kromer, Ximian Xiao, Gert Fricker, Walter Mier, … , 12 December 2023. - 18 S.
In: Drug Delivery and Translational Research, ISSN 2190-3948. 14(2024), 6, Seite 1660-1677
DOI: 10.1007/s13346-023-01482-w
- Hartl, Natascha Verena: Overcoming the blood-brain barrier? : Prediction of blood-brain permeability of hydrophobically modified polyethylenimine polyplexes for siRNA delivery into the brain with in vitro and in vivo models / Natascha Hartl, Bettina Gabold, Friederike Adams, Philipp Uhl, Sabrina Oerter, Sabine Gätzner, Marco… , 15 July 2023. - 17 S.
In: Journal of controlled release, ISSN 1873-4995. 360(2023), Seite 613-629
DOI: 10.1016/j.jconrel.2023.07.019
- Hammer, Maximilian: Forward light scattering of first to third generation vitreous body replacement hydrogels after surgical application compared to conventional silicone oils and vitreous body / Maximilian Hammer, Jonathan Herth, Marcel Muuss, Sonja Schickhardt, Alexander Scheuerle, Ramin Khora… , 21 October 2023. - 13 S.
In: Gels, ISSN 2310-2861. 9(2023), 10, Artikel-ID 837, Seite 1-13
DOI: 10.3390/gels9100837
- Pander, Giulia: Antibody-drug conjugates : what drives their progress? / Giulia Pander, Philipp Uhl, Nikos Kühl, Uwe Haberkorn, Jan Anderl, Walter Mier, [October 2022]. - 10 S. : Illustrationen
In: Drug discovery today, ISSN 1878-5832. 27(2022), 10 vom: Okt., Artikel-ID 103311, Seite 1-10
DOI: 10.1016/j.drudis.2022.06.011
- Hammer, Maximilian: Intravitreal application : physicochemical properties of drugs dissolved in silicone oils of different density in comparison to the porcine vitreous body / Maximilian Hammer, Sonja K. Schickhardt, Patrick R. Merz, Ramin Khoramnia, Alexander F. Scheuerle, W… , 28 June 2022. - 11 S.
In: Pharmaceutics, ISSN 1999-4923. 14(2022), 7, Artikel-ID 1364, Seite 1-11
DOI: 10.3390/pharmaceutics14071364
- Umstätter, Florian: Impact of linker modification and PEGylation of vancomycin conjugates on structure-activity relationships and pharmacokinetics / Florian Umstätter, Julia Werner, Leah Zerlin, Eric Mühlberg, Christian Kleist, Karel D. Klika, Tobia… , 28 January 2022. - 14 S.
In: Pharmaceuticals, ISSN 1424-8247. 15(2022), 2, Artikel-ID 159, Seite 1-14
DOI: 10.3390/ph15020159
- Benzel, Julia: Investigating the central nervous system disposition of actinomycin D : implementation and evaluation of cerebral microdialysis and brain tissue measurements supported by UPLC-MS/MS quantification / Julia Benzel, Gzona Bajraktari-Sylejmani, Philipp Uhl, Abigail Davis, Sreenath Nair, Stefan M. Pfist… , 17 September 2021. - 16 S.
In: Pharmaceutics, ISSN 1999-4923. 13(2021), 9, special issue, Artikel-ID 1498, Seite 1-16
DOI: 10.3390/pharmaceutics13091498
- Uhl, Philipp: Overcoming the mucosal barrier : tetraether lipid-stabilized liposomal nanocarriers decorated with cell-penetrating peptides enable oral delivery of vancomycin / Philipp Uhl, Max Sauter, Tobias Hertlein, Dominik Witzigmann, Flavia Laffleur, Götz Hofhaus, Veronik… , 2021. - 12 S.
In: Advanced therapeutics, ISSN 2366-3987. 4(2021), 4, Artikel-ID 2000247, Seite 1-12
DOI: 10.1002/adtp.202000247
- Pratsinis, Anna: Virus-derived peptides for hepatic enzyme delivery / Anna Pratsinis, Philipp Uhl, Jan Stephan Bolten, Patrick Hauswirth, Susanne Heidi Schenk, Stephan Ur… , April 12, 2021. - 11 S.
In: Molecular pharmaceutics, ISSN 1543-8392. 18(2021), 5, Seite 2004-2014
DOI: 10.1021/acs.molpharmaceut.0c01222
- Sauter, Max: Application of triple quadrupole tandem mass spectrometry to the bioanalysis of collision-induced dissociation-resistant cyclic peptides : ultra-sensitive quantification of the somatostatin-analog pasireotide utilizing UHPLC-MS/MS / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 2021
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 194(2021) Artikel-Nummer 113728, 7 Seiten
DOI: 10.1016/j.jpba.2020.113728
- Storck, Philip: Fatty acid conjugation leads to length-dependent antimicrobial activity of a synthetic antibacterial peptide (Pep19-4LF) / Philip Storck, Florian Umstätter, Sabrina Wohlfart, Cornelius Domhan, Christian Kleist, Julia Werner… , 26 November 2020. - 12 S.
In: Antibiotics, ISSN 2079-6382. 9(2020), 12, Artikel-ID 844, Seite 1-12
DOI: 10.3390/antibiotics9120844
- Umstätter, Florian: Überwindung von Vancomycinresistenzen durch Modifikation mit polykationischen Peptiden / F. Umstätter, C. Domhan, T. Hertlein, K. Ohlsen, E. Mühlberg, C. Kleist, S. Zimmermann, B. Beijer, K… , 2020. - 1 S.
In: Angewandte Chemie, ISSN 1521-3757. 132(2020), 40, Seite 17478
DOI: 10.1002/ange.202007022
- Umstätter, Florian: Überwindung von Vancomycinresistenzen durch Modifikation mit polykationischen Peptiden / Florian Umstätter, Cornelius Domhan, Tobias Hertlein, Knut Ohlsen, Eric Mühlberg, Christian Kleist, … , 2020. - 5 S.
In: Angewandte Chemie, ISSN 1521-3757. 132(2020), 23, Seite 8908-8912
DOI: 10.1002/ange.202002727
- Umstätter, Florian: Vancomycin resistance is overcome by conjugation of polycationic peptides / F. Umstätter, C. Domhan, T. Hertlein, K. Ohlsen, E. Mühlberg, C. Kleist, S. Zimmermann, B. Beijer, K… , 2020. - 1 S.
In: Angewandte Chemie, ISSN 1521-3773. 59(2020), 40, Seite 17326
DOI: 10.1002/anie.202007022
- Umstätter, Florian: Vancomycin resistance is overcome by conjugation of polycationic peptides / Florian Umstätter, Cornelius Domhan, Tobias Hertlein, Knut Ohlsen, Eric Mühlberg, Christian Kleist, … , 2020. - 5 S.
In: Angewandte Chemie, ISSN 1521-3773. 59(2020), 23, Seite 8823-8827
DOI: 10.1002/anie.202002727
- Sauter, Max: New insights into the pharmacokinetics of vancomycin after oral and intravenous administration : an investigation in beagle dogs / Max Sauter, Philipp Uhl, Andreas D. Meid, Gerd Mikus, Jürgen Burhenne, Walter E. Haefeli, 20 March 2020. - 5 S.
In: Journal of pharmaceutical sciences, ISSN 1520-6017. 109(2020), 6, Seite 2090-2094
DOI: 10.1016/j.xphs.2020.03.012
- Sauter, Max: An underestimated factor : the extent of cross-reactions modifying APIs in surface-modified liposomal preparations caused by comprised activated lipids / Max Sauter, Jürgen Burhenne, Walter E. Haefeli and Philipp Uhl, 27 September 2020
In: Molecules, ISSN 1420-3049. 25(2020,19) Artikel-Nummer 4436, 11 Seiten
DOI: 10.3390/molecules25194436
- Mühlberg, Eric: Vancomycin-lipopeptide conjugates with high antimicrobial activity on vancomycin-resistant enterococci / Eric Mühlberg, Florian Umstätter, Cornelius Domhan, Tobias Hertlein, Knut Ohlsen, Andreas Krause, Ch… , 29 May 2020
In: Pharmaceuticals, ISSN 1424-8247. 13(2020,6) Artikel-Nummer 110, 14 Seiten
DOI: 10.3390/ph13060110
- Sauter, Max: Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 22 February 2020. - 7 S.
In: Journal of pharmaceutical analysis, ISSN 2214-0883. 10(2020), 3, Seite 233-239
DOI: 10.1016/j.jpha.2020.02.008
- Sauter, Max: Ultra-sensitive quantification of the therapeutic cyclic peptide bremelanotide utilizing UHPLC-MS/MS for evaluation of its oral plasma pharmacokinetics / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 27 March 2020. - 6 S.
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 186(2020) Artikel-Nummer 113276, 6 Seiten
DOI: 10.1016/j.jpba.2020.113276
- Sauter, Max: Post-extraction disulfide bond cleavage for MS/MS quantification of collision-induced dissociation-resistant cystine-cyclized peptides and its application to the ultra-sensitive UPLC-MS/MS bioanalysis of octreotide in plasma / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 10 April 2020. - 8 S.
In: Analytica chimica acta, ISSN 1873-4324. 1114(2020), Seite 42-49
DOI: 10.1016/j.aca.2020.04.016
- Schuster, Lukas: Reporter cell assay-based functional quantification of TNF-α-antagonists in serum : a proof-of-principle study for adalimumab / Lukas Schuster, Max Sauter, Philipp Uhl, Andreas Meid, Walter E. Haefeli, Johanna Weiss, Dirk Theile, 26 February 2020. - 5 S.
In: Analytical biochemistry, ISSN 1096-0309. 596(2020) Arikel-Nummer 113646, 5 Seiten
DOI: 10.1016/j.ab.2020.113646
- Uhl, Philipp: Coating of PLA-nanoparticles with cyclic, arginine-rich cell penetrating peptides enables oral delivery of liraglutide / P. Uhl, PhD, C.Grundmann, M. Sauter, PhD, P. Storck, A. Tursch, S. Özbek, Prof, PhD, K. Leotta, R. R… , 2020. - 10 S.
In: Nanomedicine, ISSN 1549-9642. 24(2020) Artikel-Nummer 102132, 10 Seiten
DOI: 10.1016/j.nano.2019.102132
- Sauter, Max: An ultrasensitive UPLC–MS/MS assay for the quantification of the therapeutic peptide liraglutide in plasma to assess the oral and nasal bioavailability in beagle dogs / Max Sauter, Philipp Uhl, Marius Majewsky, Margaux Fresnais, Walter E. Haefeli & Jürgen Burhenne. - Zweitveröffentlichung. -
London: Future Science, 2019. - 1 Online-Ressource (12 Seiten)
DOI: 10.11588/heidok.00028429
- Mühlberg, Eric: Renaissance of vancomycin : approaches for breaking antibiotic resistance in multidrug-resistant bacteria / Eric Mühlberg, Florian Umstätter, Christian Kleist, Cornelius Domhan, Walter Mier, and Philipp Uhl, 2020. - 6 S.
In: Canadian journal of microbiology, ISSN 1480-3275. 66(2020), 1, Seite 11-16
DOI: 10.1139/cjm-2019-0309
- Domhan, Cornelius: Replacement of L-amino acids by D-amino acids in the antimicrobial peptide ranalexin and its consequences for antimicrobial activity and biodistribution / Cornelius Domhan, Philipp Uhl, Christian Kleist, Stefan Zimmermann, Florian Umstätter, Karin Leotta,… , 17 August 2019
In: Molecules, ISSN 1420-3049. 24(2019,16) Artikel-Nummer 2987,12 Seiten
DOI: 10.3390/molecules24162987
- Sieber, Sandro: Zebrafish as a predictive screening model to assess macrophage clearance of liposomes in vivo / Sandro Sieber, Philip Grossen, Philipp Uhl, Pascal Detampel, Walter Mier, Dominik Witzigmann, Jörg H… , 17 January 2019. - 12 S.
In: Nanomedicine, ISSN 1549-9642. 17(2019), Seite 82-93
DOI: 10.1016/j.nano.2018.11.017
- Witzigmann, Dominik: Optimization-by-design of hepatotropic lipid nanoparticles targeting the sodium-taurocholate cotransporting polypeptide / Dominik Witzigmann, Philipp Uhl, Sandro Sieber, Christina Kaufman, Tomaz Einfalt, Katrin Schöneweis,… , 23 July 2019. - 28 S.
In: eLife, ISSN 2050-084X. 8(2019) Artikel-Nummer e42276, 28 Seiten
DOI: 10.7554/eLife.42276
- Sauter, Max: An ultrasensitive UPLC-MS/MS assay for the quantification of the therapeutic peptide liraglutide in plasma to assess the oral and nasal bioavailability in beagle dogs / Max Sauter, Philipp Uhl, Marius Majewsky, Margaux Fresnais, Walter E Haefeli and Jürgen Burhenne, 16 May 2019. - 12 S.
In: Bioanalysis, ISSN 1757-6199. 11(2019), 9, Seite 887-898
DOI: 10.4155/bio-2018-0322
- Sauter, Max: An ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasma / Max Sauter, Philipp Uhl, Kathrin I. Foerster, Isabelle Mohr, Rahel T. Höne, Uta Merle, Jürgen Burhen… , 27 June 2019. - 6 S.
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 174(2019), Seite 633-638
DOI: 10.1016/j.jpba.2019.06.015
- Kruse, Sebastian: Therapeutic vaccination using minimal HPV16 epitopes in a novel MHC-humanized murine HPV tumor model / Sebastian Kruse, Marleen Büchler, Philipp Uhl, Max Sauter, Philipp Scherer, Tammy C.T. Lan, Samantha… , 2019
In: OncoImmunology, ISSN 2162-402X. 8(2019,1) Artikel-Nummer e1524694, ? Seiten
DOI: 10.1080/2162402X.2018.1524694
- Domhan, Cornelius: A novel tool against multiresistant bacterial pathogens : lipopeptide modification of the natural antimicrobial peptide ranalexin for enhanced antimicrobial activity and improved pharmacokinetics / Cornelius Domhan, Philipp Uhl, Anna Meinhardt, Stefan Zimmermann, Christian Kleist, Thomas Lindner, … , 2018. - 11 S.
In: International journal of antimicrobial agents, ISSN 1872-7913. 52(2018), 1, Seite 52-62
DOI: 10.1016/j.ijantimicag.2018.03.023
- Uhl, Philipp: Oral delivery of vancomycin by tetraether lipid liposomes / Philipp Uhl, Silvia Pantze, Philip Storck, Johannes Parmentier, Dominik Witzigmann, Götz Hofhaus, Jö… , 14 July 2017. - 8 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 108(2017), Seite 111-118
DOI: 10.1016/j.ejps.2017.07.013
- Uhl, Philipp: Orale Verfügbarkeit von Peptidwirkstoffen mittels liposomalen Formulierungen / vorgelegt von Apotheker Philipp Jonathan Uhl. -
Heidelberg, 2017. - xx, 111 Seiten : Illustrationen, Diagramme
- Uhl, Philipp: A liposomal formulation for the oral application of the investigational hepatitis B drug Myrcludex B / P. Uhl, F. Helm, G. Hofhaus, S. Brings, C. Kaufman, Karin Leotta, S. Urban, U. Haberkorn, W. Mier, G… , 2 April 2016. - 8 S.
In: European journal of pharmaceutics and biopharmaceutics, ISSN 1873-3441. 103(2016), Seite 159-166
DOI: 10.1016/j.ejpb.2016.03.031
- Tremmel, Robin: Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes / Robin Tremmel, Philipp Uhl, Frieder Helm, Dominik Wupperfeld, Max Sauter, Walter Mier, Wolfgang Stre… , 20 August 2016. - 9 S.
In: International journal of pharmaceutics, ISSN 1873-3476. 512(2016), 1, Seite 87-95
DOI: 10.1016/j.ijpharm.2016.08.040
- Uhl, Philipp: Radionuclides in drug development / Philipp Uhl, Gert Fricker, Uwe Haberkorn and Walter Mier. - 11 S.
In: Drug discovery today, ISSN 1878-5832. 20(2015), 2, S. 198-208
DOI: 10.1016/j.drudis.2014.09.027
- Uhl, Philipp: Current status in the therapy of liver diseases / Philipp Uhl, Gert Fricker, Uwe Haberkorn and Walter Mier. - 13 S.
In: International journal of molecular sciences, ISSN 1422-0067. 15(2014), 5, S. 7500-7512
DOI: 10.3390/ijms15057500
