heiBIB: Bartholomä, Cynthia C.

Bartholomä, Cynthia C. Dr.Universität HeidelbergHeidelberg

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englisch (30)

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Publikationen in heiBIB

Abdul-Razak, Hayder: Molecular evidence of genome editing in a mouse model of immunodeficiency / H.H. Abdul-Razak, C.J. Rocca, S.J. Howe, M.E. Alonso-Ferrero, J. Wang, R. Gabriel, C.C. Bartholomae,… , 29 May 2018. - 13 S.
In: Scientific reports, ISSN 2045-2322. 8(2018) Artikel-Nummer 8214, 13 Seiten
DOI: 10.1038/s41598-018-26439-9
Scholz, Simone: Lentiviral vector promoter is decisive for aberrant transcript formation / Simone J. Scholz, Raffaele Fronza, Cynthia C. Bartholomä, Daniela Cesana, Eugenio Montini, Christof … , August 18, 2017. - 11 S.
In: Human gene therapy, ISSN 1557-7422. 28(2017), 10, Seite 875-885
DOI: 10.1089/hum.2017.162
Negre, Olivier: Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease / Olivier Negre, Cynthia Bartholomae, Yves Beuzard, Marina Cavazzana, Lauryn Christiansen, Céline Cour… , 2015 Feb.. - 18 S.
In: Current gene therapy, ISSN 1875-5631. 15(2015), 1, Seite 64-81
DOI: 10.2174/1566523214666141127095336
Cantore, Alessio: Liver-directed lentiviral gene therapy in a dog model of hemophilia B / Alessio Cantore, Marco Ranzani, Cynthia C. Bartholomae, Monica Volpin, Patrizia Della Valle, Frances… , 4 March 2015. - 12 S.
In: Science translational medicine, ISSN 1946-6242. 7(2015,227) Artikel-Nummer 277ra28, 12 Seiten
DOI: 10.1126/scitranslmed.aaa1405
Alaee, Farhang: Biodistribution of LV-TSTA transduced rat bone marrow cells used for “ex-vivo” regional gene therapy for bone repair / Farhang Alaee, Cynthia Bartholomae, Osamu Sugiyama, Mandeep S. Virk, Hicham Drissi, Qian Wu, Manfred… , 2015. - 11 S.
In: Current gene therapy, ISSN 1875-5631. 15(2015), 5, Seite 481-491
DOI: 10.2174/1566523215666150812120229
Negre, Olivier: Preclinical evaluation of efficacy and safety of an improved lentiviral vector for the treatment of β-thalassemia and sickle cell disease / Olivier Negre, Cynthia Bartholomä, Yves Beuzard, Marina Cavazzana, Lauryn Christiansen, Céline Courn… , 2015. - 18 S.
In: Current gene therapy, ISSN 1875-5631. 15(2015), 1, Seite 64-81
DOI: 10.2174/1566523214666141127095336
Bartholomä, Cynthia C.: Integration-deficient lentiviral vectors expressing codon-optimized R338L human FIX restore normal hemostasis in hemophilia B mice / Thipparat Suwanmanee, Genlin Hu, Tong Gui, Cynthia C Bartholomae, Ina Kutschera, Christof von Kalle,… , 7 January 2014. - 8 S.
In: Molecular therapy, ISSN 1525-0024. 22(2014), 3, Seite 567-574
DOI: 10.1038/mt.2013.188
Gabriel, Richard: Linear amplification mediated PCR : localization of genetic elements and characterization of unknown flanking DNA / Richard Gabriel, Ina Kutschera, Cynthia C. Bartholomae, Christof von Kalle, Manfred Schmidt, 25 June 2014. - 1 Online-Ressource (1 Videodatei, 11:57 min) : farbig
In: JoVE, ISSN 1940-087X. (2014,88) Artikel-Nummer e51543, 8 Seiten
DOI: 10.3791/51543
Hovestadt, Volker: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing / Volker Hovestadt, David T.W. Jones, Simone Picelli, Wei Wang, Marcel Kool, Paul A. Northcott, Marc S… , 2014. - 5 S.
In: Nature, ISSN 1476-4687. 510(2014), 7506, Seite 537-541
DOI: 10.1038/nature13268
Northcott, Paul A.: Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma / Paul A. Northcott, Catherine Lee, Thomas Zichner, Adrian M. Stütz, Serap Erkek, Daisuke Kawauchi, Da… , 24 July 2014. - 7 S.
In: Nature, ISSN 1476-4687. 511(2014), 7510, Seite 428-434
DOI: 10.1038/nature13379
Stephan, Christoph: Impact of raltegravir on HIV-1 RNA and DNA forms following initiation of antiretroviral therapy in treatment-naive patients / Christoph Stephan, Hanna-Mari Baldauf, Joanne Barry,Frank A. Giordano, Cynthia C. Bartholomae, Annet… , 2014. - 10 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 69(2014), 10, Seite 2809-2818
DOI: 10.1093/jac/dku213
Kool, Marcel: Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition / Marcel Kool, David T.W. Jones, Natalie Jäger, Paul A. Northcott, Trevor J. Pugh, Volker Hovestadt, R… , 17 March 2014. - 13 S.
In: Cancer cell, ISSN 1878-3686. 25(2014), 3, Seite 393-405
DOI: 10.1016/j.ccr.2014.02.004
Cesana, Daniela: Uncovering and dissecting the genotoxicity of self-inactivating lentiviral vectors in vivo / Daniela Cesana, Marco Ranzani, Monica Volpin, Cynthia Bartholomae, Caroline Duros, Alexandre Artus, … , 2014. - 12 S.
In: Molecular therapy, ISSN 1525-0024. 22(2014), 4, Seite 774-785
DOI: 10.1038/mt.2014.3
Saeed, Muhammad: Comparison between several integrase-defective lentiviral vectors reveals increased integration of an HIV vector bearing a D167H mutant / Muhammad Qamar Saeed, Noelle Dufour, Cynthia Bartholmae, Urzula Sieranska, Malaika Knopf, Eloïse Thi… , 2014. - 12 S.
In: Molecular therapy, ISSN 2162-2531. 3(2014) Artikel-Nr.e213,12S
DOI: 10.1038/mtna.2014.65
Eißmann, Moritz: Overexpression of the anti-apoptotic protein AVEN contributes to increased malignancy in hematopoietic neoplasms / M. Eißmann, I.M. Melzer, S.B.M. Fernández, G. Michel, M. Hrabě de Angelis, G. Hoefler, P. Finkenwirt… , 2013. - 6 S.
In: Oncogene, ISSN 1476-5594. 32(2013), 20, Seite 2586-2591
DOI: 10.1038/onc.2012.263
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 2012. - 6 S.
In: Nature, ISSN 0028-0836. 488(2012), 7409 vom: 20. Juni, Seite 100-105
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 25 July 2012. - 6 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 100-105
DOI: 10.1038/nature11284
Gabriel, Richard: An unbiased genome-wide analysis of zinc-finger nuclease specificity / Richard Gabriel, Angelo Lombardo, Anne Arens, Jeffrey C. Miller, Pietro Genovese, Christine Kaeppel,… , 7 August 2011. - 9 S.
In: Nature biotechnology, ISSN 1546-1696. 29(2011), 9 vom: Sept., Seite 816-823
DOI: 10.1038/nbt.1948
Tolar, Jakub: Stem cell gene therapy for Fanconi anemia : report from the 1st International Fanconi anemia gene therapy working group meeting / Jakub Tolar, Jennifer E Adair, Michael Antoniou, Cynthia C Bartholomae, Pamela S Becker, Bruce R Bla… , 2011. - 6 S.
In: Molecular therapy, ISSN 1525-0024. 19(2011), 7 vom: Juli, Seite 1193-1198
DOI: 10.1038/mt.2011.78
Kang, Hyoung Jin: Retroviral gene therapy for X-linked chronic granulomatous disease : results from phase I/II trial / Hyoung Jin Kang, Cynthia C Bartholomae, Anna Paruzynski, Anne Arens, Sujeong Kim, Seung Shin Yu, You… , 30 August 2011. - 10 S.
In: Molecular therapy, ISSN 1525-0024. 19(2011), 11, Seite 2092-2101
DOI: 10.1038/mt.2011.166
Deichmann, Annette: Insertion sites in engrafted cells cluster within a limited repertoire of genomic areas after ´gammaretroviral vector gene therapy / Annette Deichmann, Martijn H Brugman, Cynthia C Bartholomae, Kerstin Schwarzwaelder, Monique MA Vers… , 2011. - 9 S.
In: Molecular therapy, ISSN 1525-0024. 19(2011), 11, Seite 2031-2039
DOI: 10.1038/mt.2011.178
Biffi, Alessandra: Lentiviral vector common integration sites in preclinical models and a clinical trial reflect a benign integration bias and not oncogenic selection / Alessandra Biffi, Cynthia C. Bartolomae, Daniela Cesana, Natalie Cartier, Patrik Aubourg, Marco Ranz… , May 19 2011. - 8 S.
In: Blood, ISSN 1528-0020. 117(2011), 20, Seite 5332-5339
DOI: 10.1182/blood-2010-09-306761
Biasco, Luca: Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell / Luca Biasco, Alessandro Ambrosi, Danilo Pellin, Cynthia Bartholomae, Immacolata Brigida, Maria Grazi… , 17 January 2011. - 13 S.
In: EMBO molecular medicine, ISSN 1757-4684. 3(2011), 2, Seite 89-101
DOI: 10.1002/emmm.201000108
Bartholomä, Cynthia C.: Lentiviral vector integration profiles differ in rodent postmitotic tissues / Cynthia C Bartholomae, Anne Arens, Kamaljit S Balaggan, Rafael J Yáñez-Muñoz, Eugenio Montini, Steve… , 2011. - 8 S.
In: Molecular therapy, ISSN 1525-0024. 19(2011), 4 vom: Apr., Seite 703-710
DOI: 10.1038/mt.2011.19
Deichmann, Annette: Insertion sites in encrafted cells cluster within a limited repertoire of genomic areas after gammaretroviral vector gene therapy / A. Deichmann ... C. C. Bartholomae ... R. Gabriel; H. Glimm; U. Abel ..., 2011. - 9 S.
In: Molecular therapy, ISSN 1525-0016. 19(2011), 11, Seite 2031-2039
Bartholomä, Cynthia C.: Lentiviral vector integration profiles differ in rodent postmitotic tissues / Cynthia C Bartholomae, Anne Arens, Kamaljit S Balaggan, Rafael J Yáñez-Muñoz, Eugenio Montini, Steve… , 2011. - 8 S.
In: Molecular therapy, ISSN 1525-0016. 19(2011), 4, Seite 703-710
Abel, Ulrich: Analyzing the number of common integration sites of viral vectors : new methods and computer programs / U. Abel; A. Deichmann; A. Nowrouzi; R. Gabriel; C. C. Bartholomae; H. Glimm; C. von Kalle; M. Schmid… , 2011. - 8 S.
In: PLOS ONE, ISSN 1932-6203. 6(2011,10) Artikel-Nr. e24247, 8 S.
DOI: 10.1371/journal.pone.0024247
Gama-Norton, Leonor: Retroviral vector performance in defined chromosomal loci of modular packaging cell lines / L. Gama-Norton, S. Herrmann, R. Schucht, A.S. Coroadinha, R. Löw, P.M. Alves, C.C. Bartholomae, M. S… , June 18, 2010. - 12 S.
In: Human gene therapy, ISSN 1557-7422. 21(2010), 8 vom: Aug., Seite 979-991
DOI: 10.1089/hum.2009.089
Paruzynski, Anna: Genome-wide high-throughput integrome analyses by nrLAM-PCR and next-generation sequencing / Anna Paruzynski, Anne Arens, Richard Gabriel, Cynthia C. Bartholomae, Simone Scholz, Wei Wang, Steph… , 08 July 2010. - 10 S.
In: Nature protocols, ISSN 1750-2799. 5(2010), 8, Seite 1379-1395
DOI: 10.1038/nprot.2010.87
Cattoglio, Claudia: High-definition mapping of retroviral integration sites defines the fate of allogeneic T cells after donor lymphocyte infusion / Claudia Cattoglio, Giulietta Maruggi, Cynthia Bartholomae, Nirav Malani, Danilo Pellin, Fabienne Coc… , December 22, 2010. - 14 S.
In: PLOS ONE, ISSN 1932-6203. 5(2010), 12, Artikel-ID e15688, Seite 1-14
DOI: 10.1371/journal.pone.0015688

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