Tilburg, Cornelis M. van MD, PhDUniversität HeidelbergHeidelberg
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Publications in heiBIB 
- Filippidou, Maria: Soft tissue undifferentiated sarcoma carrying a novel Onecut1::Nutm1 fusion : letter to the editor / Maria Filippidou, Stavros Glentis, Efthymia Rigatou, Philipp Sievers, Florian Selt, Efthymios Dimitr… , January 2025. - 4 S. : Illustrationen
In: Pediatric blood & cancer, ISSN 1545-5017. 72(2025), 1 vom: Jan., Artikel-ID e31427, Seite 1-4
DOI: 10.1002/pbc.31427
- O’Hare, Patricia: Resistance, rebound, and recurrence regrowth patterns in pediatric low-grade glioma treated by MAPK inhibition : a modified Delphi approach to build international consensus-based definitions : international pediatric low-grade glioma coalition / Patricia O’Hare, Tabitha Cooney, Peter de Blank, David H. Gutmann, Mark Kieran, Till Milde, Jason Fa… , August 2024. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 26(2024), 8 vom: Aug., Seite 1357-1366
DOI: 10.1093/neuonc/noae074
- Wallin, Sofia: Implementing data on targeted therapy from the INFORM registry platform for children with relapsed cancer in Sweden / Sofia Wallin, Ingrid Øra, Gabriela Prochazka, Johanna Sandgren, Caroline Björklund, Gustaf Ljungman,… , 31 January 2024. - 11 S.
In: Frontiers in oncology, ISSN 2234-943X. 14(2024), Artikel-ID 1340099, Seite 1-11
DOI: 10.3389/fonc.2024.1340099
- Tilburg, Cornelis M. van: LOGGIC/FIREFLY-2 : a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration / Cornelis M. van Tilburg, Lindsay B. Kilburn, Sébastien Perreault, Rene Schmidt, Amedeo A. Azizi, Ofe… , 30 January 2024. - 11 S. : Illustrationen
In: BMC cancer, ISSN 1471-2407. 24(2024), Artikel-ID 147, Seite 1-11
DOI: 10.1186/s12885-024-11820-x
- Heipertz, Anna-Elisa: Outcome of children and adolescents with relapsed/refractory/progressive malignancies treated with molecularly informed targeted drugs in the pediatric precision oncology registry INFORM / Anna-Elisa Heipertz, MD, Kristian W. Pajtler, MD, Elke Pfaff, MD, Kathrin Schramm, Dr. rer. nat., Mi… , June 26, 2023. - 12 S. : Illustrationen
In: JCO precision oncology, ISSN 2473-4284. (2023), 7, Artikel-ID e2300015, Seite 1-12
DOI: 10.1200/PO.23.00015
- Kolodziejczak, Anna: Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome / Anna S Kolodziejczak, Lea Guerrini-Rousseau, Julien Masliah Planchon, Jonas Ecker, Florian Selt, Mar… , December 2023. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 12 vom: Dez., Seite 2273-2286
DOI: 10.1093/neuonc/noad114
- Vollmer, Johanna: Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells / Johanna Vollmer, Jonas Ecker, Thomas Hielscher, Gintvile Valinciute, Johannes Ridinger, Nora Jamalad… , 3 October 2023. - 16 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 164(2023), 3, Seite 617-632
DOI: 10.1007/s11060-023-04445-w
- Sigaud, Romain: MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas / Romain Sigaud, Thomas K. Albert, Caroline Hess, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Ca… , 27 July 2023. - 21 S.
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 4533, Seite 1-21
DOI: 10.1038/s41467-023-40235-8
- Ecker, Jonas: Corrigendum to ‘Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry’ [Eur J Cancer 180 (2023) 71-84] / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , May 2023. - 2 S.
In: European journal of cancer, ISSN 1879-0852. 184(2023) vom: Mai, Seite 200-201
DOI: 10.1016/j.ejca.2023.02.024
- Ecker, Jonas: Molecular diagnostics enables detection of actionable targets : the Pediatric Targeted Therapy 2.0 registry / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , February 2023. - 14 S. : Illustrationen
In: European journal of cancer, ISSN 1879-0852. 180(2023) vom: Feb., Seite 71-84
DOI: 10.1016/j.ejca.2022.11.015
- Tilburg, Cornelis M. van: Pediatric precision oncology in translation : from diagnostic platforms to clinical trails / vorgelegt von Dr. Cornelis M. van Tilburg. -
Heidelberg, 2022. - 1 Band (verschiedene Seitenzählungen) : Illustrationen, Diagramme
- Langenberg, Karin: Implementation of paediatric precision oncology into clinical practice : the individualized therapies for children with cancer program ‘iTHER’ / Karin P.S. Langenberg, Michael T. Meister, Jette J. Bakhuizen, Judith M. Boer, Natasha K.A. van Eijk… , 29 September 2022. - 15 S.
In: European journal of cancer, ISSN 1879-0852. 175(2022), Seite 311-325
DOI: 10.1016/j.ejca.2022.09.001
- Peterziel, Heike: Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM / Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yann… , 27 December 2022. - 17 S.
In: npj precision oncology, ISSN 2397-768X. 6(2022), Artikel-ID 94, Seite 1-17
DOI: 10.1038/s41698-022-00335-y
- Deng, Maximilian: Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B / Maximilian Y. Deng, Dominik Sturm, Elke Pfaff, Martin Sill, Damian Stichel, Gnana Prakash Balasubram… , 20 September 2021. - 11 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 5530, Seite 1-11
DOI: 10.1038/s41467-021-25708-y
- Kummar, Shivaani: Quality of life in adult and pediatric patients with tropomyosin receptor kinase fusion cancer receiving larotrectinib / Shivaani Kummar, Jordan Berlin, Leo Mascarenhas, Cornelis M. van Tilburg, Birgit Geoerger, Ulrik N. … , 2 April 2021. - 14 S.
In: Current problems in cancer, ISSN 1535-6345. 45(2021), 6 vom: Dez., Artikel-ID 100734, Seite 1-14
DOI: 10.1016/j.currproblcancer.2021.100734
- Tilburg, Cornelis M. van: The pediatric precision oncology INFORM registry : clinical outcome and benefit for patients with very high-evidence targets / Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler, Karin P. S. Langenberg, Petra Fiesel, Barb… , August 9, 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 11, Seite 2764-2779
DOI: 10.1158/2159-8290.CD-21-0094
- Stenzinger, Albrecht: Diagnostik und Therapie von Tumoren mit NTRK-Genfusionen / Albrecht Stenzinger, Cornelis M. van Tilburg, Ghazaleh Tabatabai, Florian Länger, Norbert Graf, Fran… , 2021. - 13 S.
In: Der Pathologe, ISSN 1432-1963. 42(2021), 1, Seite 103-115
DOI: 10.1007/s00292-020-00864-y
- Ecker, Jonas: Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma / Jonas Ecker, Venu Thatikonda, Gianluca Sigismondo, Florian Selt, Gintvile Valinciute, Ina Oehme, Car… , 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 2 vom: Feb., Seite 226-239
DOI: 10.1093/neuonc/noaa191
- Pfaff, Elke: NTRK alterations in pediatric high-risk malignancies identified through European clinical sequencing programs constitute promising drug targets / Elke Pfaff, Tiphaine Adam de Beaumais, Antonin Marchais, Cornelis M. van Tilburg, Mirjam Blattner-Jo… , February 26, 2021. - 5 S.
In: JCO precision oncology, ISSN 2473-4284. 5(2021), Seite 450-454
DOI: 10.1200/PO.20.00417
- Selt, Florian: Response to trametinib treatment in progressive pediatric low-grade glioma patients / Florian Selt, Cornelis M. van Tilburg, Brigitte Bison, Philipp Sievers, Inga Harting, Jonas Ecker, K… , 7 October 2020. - 12 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 149(2020) vom: Sept., Seite 499-510
DOI: 10.1007/s11060-020-03640-3
- Tilburg, Cornelis M. van: INFORM2 NivEnt : the first trial of the INFORM2 biomarker driven phase I/II trial series : the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies / Cornelis M. van Tilburg, Ruth Witt, Melanie Heiss, Kristian W. Pajtler, Christoph Plass, Isabel Posc… , 05 June 2020. - 12 S.
In: BMC cancer, ISSN 1471-2407. 20(2020) vom: Juni, Artikel-ID 523, Seite 1-12
DOI: 10.1186/s12885-020-07008-8
- Italiano, Antoine: Larotrectinib versus prior therapies in tropomyosin receptor kinase fusion cancer : an intra-patient comparative analysis / Antoine Italiano, Shivani Nanda, Andrew Briggs, Jesus Garcia-Foncillas, Ulrik Lassen, Gilles Vassal,… , 4 November 2020
In: Cancers, ISSN 2072-6694. 12(2020,11) Artikel-Nummer 3246, 10 Seiten
DOI: 10.3390/cancers12113246
- Pearson, Andrew D. J.: ACCELERATE and European Medicines Agency Paediatric Strategy Forum for medicinal product development of checkpoint inhibitors for use in combination therapy in paediatric patients / Andrew D.J. Pearson, Claudia Rossig, Giovanni Lesa, Scott J. Diede, Susan Weiner, John Anderson, Jul… , March 2020. - 15 S.
In: European journal of cancer, ISSN 1879-0852. 127(2020), Seite 52-66
DOI: 10.1016/j.ejca.2019.12.029
- Usta, Diren: A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells / Diren Usta, Romain Sigaud, Juliane L. Buhl, Florian Selt, Viktoria Marquardt, David Pauck, Jennifer … , May 25, 2020. - 14 S.
In: Molecular cancer therapeutics, ISSN 1538-8514. 19(2020), 8, Seite 1737-1750
DOI: 10.1158/1535-7163.MCT-19-1021
- Hong, David S.: Larotrectinib in patients with TRK fusion-positive solid tumours : a pooled analysis of three phase 1/2 clinical trials / David S Hong, Steven G DuBois, Shivaani Kummar, Anna F Farago, Catherine M Albert, Kristoffer S Rohr… , [April 2020]. - 10 S. : Diagramme
In: The lancet, ISSN 1474-5488. 21(2020), 4, Seite 531-540
DOI: 10.1016/S1470-2045(19)30856-3
- Tilburg, Cornelis M. van: Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia / Cornelis M. van Tilburg, Till Milde, Ruth Witt, Jonas Ecker, Thomas Hielscher, Angelika Seitz, Jens-… , 10 December 2019. - 15 S.
In: Clinical epigenetics, ISSN 1868-7083. 11(2019) Artikel-Nummer 188, 15 Seiten
DOI: 10.1186/s13148-019-0775-1
- Gnekow, Astrid K.: SIOP-E-BTG and GPOH guidelines for diagnosis and treatment of children and adolescents with low grade glioma / Astrid K. Gnekow, Daniela Kandels, Cornelis van Tilburg, Amedeo A. Azizi, Enrico Opocher, Tore Stokl… , 2019 May 20. - 29 S.
In: Klinische Pädiatrie, ISSN 1439-3824. 231(2019), 03, Seite 107-135
DOI: 10.1055/a-0889-8256
- Saffari, Afshin: Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study / Afshin Saffari, Ines Brösse, Adelheid Wiemer-Kruel, Bernd Wilken, Paula Kreuzaler, Andreas Hahn, Mat… , 03 May 2019. - 13 S.
In: Orphanet journal of rare diseases, ISSN 1750-1172. 14(2019), Artikel-ID 96, Seite 1-13
DOI: 10.1186/s13023-019-1077-6
- Pfaff, Elke: Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine : the INFORM study experience / Elke Pfaff, Ahmed El Damaty, Gnana Prakash Balasubramanian, Mirjam Blattner-Johnson, Barbara C. Wors… , 22 April 2019. - 9 S.
In: European journal of cancer, ISSN 1879-0852. 114(2019), Seite 27-35
DOI: 10.1016/j.ejca.2019.03.019
- Saffari, Afshin: Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age : a multicenter retrospective study / Afshin Saffari, Ines Brösse, Adelheid Wiemer-Kruel, Bernd Wilken, Paula Kreuzaler, Andreas Hahn, Mat… . -
London: BioMed Central, 2019. - 1 Online-Ressource
- Buhl, Juliane: The senescence-associated secretory phenotype mediates oncogene-induced senescence in pediatric pilocytic astrocytoma / Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Rid… , 15 March 2019. - 16 S.
In: Clinical cancer research, ISSN 1557-3265. 25(2019), 6, Seite 1851-1866
DOI: 10.1158/1078-0432.CCR-18-1965
- Gröbner, Susanne: Author correction: The landscape of genomic alterations across childhood cancers / Susanne N. Gröbner, Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vas… , 06 June 2018. - 1 S.
In: Nature, ISSN 1476-4687. 559(2018), 7714, Seite E10-E10
DOI: 10.1038/s41586-018-0167-2
- Bächli, Heidi: Molecular diagnostics in pediatric brain tumors : impact on diagnosis and clinical decision-making - a selected case series / Heidi Bächli, Jonas Ecker, Cornelis van Tilburg, Dominik Sturm, Florian Selt, Felix Sahm, Christian … , 11. Juli 2018. - 9 S.
In: Klinische Pädiatrie, ISSN 1439-3824. 230(2018), 06, Seite 305-313
DOI: 10.1055/a-0637-9653
- Gröbner, Susanne: The landscape of genomic alterations across childhood cancers, 28.02.2018. - 7 S.
In: Nature, ISSN 1476-4687. 555(2018), Seite 321-327
DOI: 10.1038/nature25480
- Tilburg, Cornelis M. van: Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib / Cornelis M. van Tilburg, Florian Selt, Felix Sahm, Heidi Bächli, Stefan M. Pfister, Olaf Witt, Till … , 2018. - 4 S.
In: Pediatric blood & cancer, ISSN 1545-5017. 65(2018), 3, Artikel-ID e26893, Seite 1-4
DOI: 10.1002/pbc.26893
- Jones, Barbara Christine: Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study / Barbara C. Worst, Cornelis M. van Tilburg, Gnana Prakash Balasubramanian, Petra Fiesel, Ruth Witt, A… , 29 July 2016. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 65(2016), Seite 91-101
DOI: 10.1016/j.ejca.2016.06.009
- Selt, Florian: Pediatric targeted therapy : clinical feasibility of personalized diagnostics in children with relapsed and progressive tumors / Florian Selt, Alica Deiß, Andrey Korshunov, David Capper, Hendrik Witt, Cornelis M. van Tilburg, Dav… , 7 October 2015. - 11 S.
In: Brain pathology, ISSN 1750-3639. 26(2016), 4, Seite 506-516
DOI: 10.1111/bpa.12326
- Bender, Sebastian: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma / Sebastian Bender, Jan Gronych, Hans-Jörg Warnatz, Barbara Hutter, Susanne Gröbner, Marina Ryzhova, E… , 17 October 2016. - 9 S.
In: Nature medicine, ISSN 1546-170X. 22(2016), 11, Seite 1314-1322
DOI: 10.1038/nm.4204
