Raffel, Simon PD Dr. med.Universität HeidelbergHeidelberg
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Publications in heiBIB 
- Lenk, Lennart: The IL-7R antagonist lusvertikimab reduces leukemic burden in xenograft ALL via antibody-dependent cellular phagocytosis / Lennart Lenk, Irène Baccelli, Anna Laqua, Julia Heymann, Claas Reimer, Anna Dietterle, Dorothee Wint… , June 27 2024. - 14 S. : Illustrationen
In: Blood, ISSN 1528-0020. 143(2024), 26, Seite 2735-2748
DOI: 10.1182/blood.2023021088
- Stelljes, Matthias: Inotuzumab ozogamicin as induction therapy for patients older than 55 years with Philadelphia chromosome-negative B-precursor ALL / Matthias Stelljes (MD), Simon Raffel (MD), Nael Alakel (MD), Ralph Wäsch (MD), Mustafa Kondakci (MD)… , January 2024. - 10 S. : Diagramme
In: Journal of clinical oncology, ISSN 1527-7755. 42(2024), 3 vom: Jan., Seite 273-282
DOI: 10.1200/JCO.23.00546
- Sedloev, David: Proteasome inhibition enhances the anti-leukemic efficacy of chimeric antigen receptor (CAR) expressing NK cells against acute myeloid leukemia / David Sedloev, Qian Chen, Julia M. Unglaub, Nicola Schanda, Yao Hao, Eleni Besiridou, Brigitte Neube… , 16 September 2024. - 22 S. : Illustrationen
In: Journal of hematology & oncology, ISSN 1756-8722. 17(2024), Artikel-ID 85, Seite 1-22
DOI: 10.1186/s13045-024-01604-y
- Neumann, Martin: Molecular subgroups of T-cell acute lymphoblastic leukemia in adults treated according to pediatric-based GMALL protocols / Martin Neumann, Thomas Beder, Lorenz Bastian, Sonja Hänzelmann, Miriam Bultmann, Nadine Wolgast, Ali… , 14 May 2024. - 10 S. : Diagramme
In: Leukemia, ISSN 1476-5551. 38(2024), 6, Seite 1213-1222
DOI: 10.1038/s41375-024-02264-0
- Weidenauer, Katharina: The ribosomal protein S6 kinase alpha-1 (RPS6KA1) induces resistance to venetoclax/azacitidine in acute myeloid leukemia / Katharina Weidenauer, Christina Schmidt, Christian Rohde, Cornelius Pauli, Maximilian F. Blank, Dani… , 6 July 2023. - 15 S. : Illustrationen
In: Leukemia, ISSN 1476-5551. 37(2023), 8 vom: Aug., Seite 1611-1625
DOI: 10.1038/s41375-023-01951-8
- Waclawiczek, Alexander: Combinatorial BCL2 family expression in acute myeloid leukemia stem cells predicts clinical response to Azacitidine/Venetoclax / Alexander Waclawiczek, Aino-Maija Leppä, Simon Renders, Karolin Stumpf, Cecilia Reyneri, Barbara Bet… , June 02 2023. - 20 S. : Illustrationen
In: Cancer discovery, ISSN 2159-8290. 13(2023), 6, Seite 1408-1427
DOI: 10.1158/2159-8290.CD-22-0939
- Gökbuget, Nicola: General condition and comorbidity of long-term survivors of adult acute lymphoblastic leukemia / Nicola Gökbuget, Kristina Ihrig, Michael Stadler, Matthias Stelljes, Ahmet Elmaagacli, Michael Starc… , July, 2023. - 10 S. : Illustrationen
In: Haematologica, ISSN 1592-8721. 108(2023), 7 vom: Juli, Seite 1758-1767
DOI: 10.3324/haematol.2022.281820
- Beneyto Calabuig, Sergi: Clonally resolved single-cell multi-omics identifies routes of cellular differentiation in acute myeloid leukemia / Sergi Beneyto-Calabuig, Anne Kathrin Merbach, Jonas-Alexander Kniffka, Magdalena Antes, Chelsea Szu-… , 4 May 2023. - 25 S. : Diagramme, Illustrationen
In: Cell stem cell, ISSN 1875-9777. 30(2023), 5 vom: Mai, Seite 706-721.e8
DOI: 10.1016/j.stem.2023.04.001
- Zhou, Fengbiao: A dynamic rRNA ribomethylome drives stemness in acute myeloid leukemia / Fengbiao Zhou, Nesrine Aroua, Yi Liu, Christian Rohde, Jingdong Cheng, Anna-Katharina Wirth, Daria F… , February 06 2023. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 13(2023), 2 vom: Feb., Seite 332-347
DOI: 10.1158/2159-8290.CD-22-0210
- Janssen, Maike: Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1 / Maike Janssen, Christina Schmidt, Peter-Martin Bruch, Maximilian F. Blank, Christian Rohde, Alexande… , December 15, 2022. - 17 S. : Illustrationen, Diagramme
In: Blood, ISSN 1528-0020. 140(2022), 24, Seite 2594-2610
DOI: 10.1182/blood.2021014241
- Raffel, Simon: Cellular hierarchies predict drug response in acute myeloid leukemia / Simon Raffel, Lars Velten, and Simon Haas, September 12, 2022. - 3 S.
In: Cancer cell, ISSN 1878-3686. 40(2022), 9, Seite 917-919
DOI: 10.1016/j.ccell.2022.08.019
- Kotrová, Michaela: Prognostic value of low-level MRD in adult acute lymphoblastic leukemia detected by low- and high-throughput methods / Michaela Kotrová, Johannes Koopmann, Heiko Trautmann, Nael Alakel, Joachim Beck, Kathrin Nachtkamp, … , May 16, 2022. - 5 S.
In: Blood advances, ISSN 2473-9537. 6(2022), 10, Seite 3006-3010
DOI: 10.1182/bloodadvances.2021006727
- Hernández-Malmierca, Pablo: Antigen presentation safeguards the integrity of the hematopoietic stem cell pool / Pablo Hernández-Malmierca, Dominik Vonficht, Alexandra Schnell, Hannah J. Uckelmann, Alina Bollhagen… , 5 May 2022. - 26 S.
In: Cell stem cell, ISSN 1875-9777. 29(2022), 5, Seite 760-775.e10
DOI: 10.1016/j.stem.2022.04.007
- Poisa-Beiro, Laura: Glucose metabolism and aging of hematopoietic stem and progenitor cells / Laura Poisa-Beiro, Jonathan J.M. Landry, Simon Raffel, Motomu Tanaka, Judith Zaugg, Anne-Claude Gavi… , 11 March 2022. - 16 S.
In: International journal of molecular sciences, ISSN 1422-0067. 23(2022), 6, Artikel-ID 3028, Seite 1-16
DOI: 10.3390/ijms23063028
- Saeed, Borhan R.: Analysis of nonleukemic cellular subcompartments reconstructs clonal evolution of acute myeloid leukemia and identifies therapy-resistant preleukemic clones / Borhan R. Saeed, Linda Manta, Simon Raffel, Paul Theodor Pyl, Eike C. Buss, Wenwen Wang, Volker Ecks… , 2021. - 14 S.
In: International journal of cancer, ISSN 1097-0215. 148(2021), 11, Seite 2825-2838
DOI: 10.1002/ijc.33461
- Triana, Sergio: Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states / Sergio Triana, Dominik Vonficht, Lea Jopp-Saile, Simon Raffel, Raphael Lutz, Daniel Leonce, Magdalen… , 22 November 2021. - 13 S.
In: Nature immunology, ISSN 1529-2916. 22(2021), 12, Seite 1577-1589
DOI: 10.1038/s41590-021-01059-0
- Velten, Lars: Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics / Lars Velten, Benjamin A. Story, Pablo Hernández-Malmierca, Simon Raffel, Daniel R. Leonce, Jennifer … , 01 March 2021. - 13 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 1366, Seite 1-13
DOI: 10.1038/s41467-021-21650-1
- Raffel, Simon: Molekulare und funktionelle Charakterisierung von Leukämiestammzellen und gesunden hämatopoetischen Stammzellen / vorgelegt von Dr. med. Simon Raffel. -
Heidelberg, 2020. - 1 Band (verschiedene Seitenzählungen) : Illustrationen, Diagramme
- Raffel, Simon: Quantitative proteomics reveals specific metabolic features of acute myeloid leukemia stem cells / Simon Raffel, Daniel Klimmeck, Mattia Falcone, Aykut Demir, Alireza Pouya, Petra Zeisberger, Christo… , June 18, 2020. - 13 S.
In: Blood, ISSN 1528-0020. 136(2020), 13, Seite 1507-1519
DOI: 10.1182/blood.2019003654
- Poisa-Beiro, Laura: Glycogen accumulation, central carbon metabolism, and aging of hematopoietic stem and progenitor cells / Laura Poisa-Beiro, Judith Thoma, Jonathan Landry, Sven Sauer, Akihisa Yamamoto, Volker Eckstein, Nat… , 14 July 2020
In: Scientific reports, ISSN 2045-2322. 10(2020) Artikel-Nummer 11597, 11 Seiten
DOI: 10.1038/s41598-020-68396-2
- Paczulla, Anna Maria: Publisher Correction : Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion / Anna M. Paczulla, Kathrin Rothfelder, Simon Raffel, Martina Konantz, Julia Steinbacher, Hui Wang, Cl… , 01 August 2019. - 1 S.
In: Nature, ISSN 1476-4687. 572(2019), 7770, Seite E19
DOI: 10.1038/s41586-019-1475-x
- Paczulla, Anna Maria: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion / Anna M. Paczulla, Kathrin Rothfelder, Simon Raffel, Martina Konantz, Julia Steinbacher, Hui Wang, Cl… , 17 July 2019. - 6 S.
In: Nature, ISSN 1476-4687. 572(2019), 7768, Seite 254–259
DOI: 10.1038/s41586-019-1410-1
- Raffel, Simon: Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut -like DNA hypermethylation / Simon Raffel, Mattia Falcone, Niclas Kneisel, Jenny Hansson, Wei Wang, Christoph Lutz, Lars Bullinge… , 01 August 2018. - 1 S.
In: Nature, ISSN 1476-4687. 560(2018), 7718, Seite E28
DOI: 10.1038/s41586-018-0403-9
- Blume, Rachel: The molecular signature of AML with increased ALDH activity suggests a stem cell origin / Rachel Blume, Eugen Rempel, Linda Manta, Borhan R. Saeed, Wenwen Wang, Simon Raffel, Olga Ermakova, … , 16 Jan 2018. - 10 S.
In: Leukemia and lymphoma, ISSN 1029-2403. 59(2018), 9, Seite 2201-2210
DOI: 10.1080/10428194.2017.1422862
- Velten, Lars: Human haematopoietic stem cell lineage commitment is a continuous process / Lars Velten, Simon F. Haas, Simon Raffel, Sandra Blaszkiewicz, Saiful Islam, Bianca P. Hennig, Chris… , 20 March 2017. - 11 S. : Illustrationen
In: Nature cell biology, ISSN 1476-4679. 19(2017), 4, Seite 271-281
DOI: 10.1038/ncb3493
- Raffel, Simon: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation / Simon Raffel, Mattia Falcone, Niclas Kneisel, Jenny Hansson, Wei Wang, Christoph Lutz, Lars Bullinge… , 16 November 2017. - 5 S.
In: Nature, ISSN 1476-4687. 551(2017), 7680, Seite 384-388
DOI: 10.1038/nature24294
- Hoang, Thanh Van: The rarity of ALDH+ cells is the key to separation of normal versus leukemia stem cells by ALDH activity in AML patients / Van T. Hoang, Eike C. Buss, Wenwen Wang, Isabel Hoffmann, Simon Raffel, Abraham Zepeda‐Moreno, Natal… , 2015. - 12 S.
In: International journal of cancer, ISSN 1097-0215. 137(2015), 3, Seite 525-536
DOI: 10.1002/ijc.29410
- Stockklausner, Clemens: A novel autosomal recessive TERT T1129P mutation in a dyskeratosis congenita family leads to cellular senescence and loss of CD34+ hematopoietic stem cells not reversible by mTOR-inhibition / Clemens Stockklausner, Simon Raffel, Julia Klermund, Obul Reddy Bandapalli, Fabian Beier, Tim H. Brü… , 11 June 2015. - 17 S.
In: Aging, ISSN 1945-4589. 7(2015), 11, Seite 911-927
- Raffel, Simon: The role of the B cell antigen receptor in c-MYC-transformed B lymphoma cells / vorgelegt von Simon Raffel, 2011. - 108 Bl. : Ill., graph. Darst.
