
Opitz, Christiane Dr. med.Universität HeidelbergHeidelberg
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Co-Autoren (Uni Heidelberg)
- Sahm, Katharina (6)
- Ott, Martina (5)
- Holfelder, Pauline (5)
- Poschet, Gernot (4)
- Panitz, Verena (4)
- Trump, Saskia (4)
- Bendszus, Martin (3)
- Berberich, Anne (3)
- Rauschenbach, Katharina (3)
- Sonner, Jana K. (3)
- Keßler, Tobias (3)
- Adam, Isabell (3)
- Prentzell, Mirja Tamara (3)
- Tykocinski, Lars-Oliver (3)
- Vollmuth, Philipp (2)
- Bunse, Lukas (2)
- Bunse, Theresa (2)
- Oezen, Iris (2)
- Niesler, Beate (2)
- Röth, Ralph (2)
- Radlwimmer, Bernhard (2)
- Tretter, Theresa (2)
- Lorenz, Hanns-Martin (2)
- Becker, Simon (2)
- Friedrich, Mirco (2)
- Deumelandt, Katrin (2)
- Plass, Christoph (2)
- Weichenhan, Dieter (2)
- Mohapatra, Soumya Ranjan (2)
- Sanghvi, Khwab (2)
- Kaul, Nathalie-Christin (2)
- Winkler, Frank (2)
- Hopf, Carsten (2)
- (weitere Einträge vorhanden...)
Co-Autoren (extern)
- Lucarelli, Philippe (1)
- Esser, Charlotte (1)
- Schulz-Knappe, Peter (1)
- Rabe, Jan-Hinrich (1)
- Seddigh, Pegah (1)
- Schramm, Alexander (1)
- Dewi, Dyah (1)
- Sers, Christine (1)
- Stupp, Roger (1)
- Hölzel, Michael (1)
- Berdel, Bianca (1)
- Falk, Christine Susanne (1)
- Dietze, Jørn (1)
- Tucher, Christine (1)
- Mohapatra, Soumya R. (1)
- Adam, Isabell (1)
- Schäuble, Sascha (1)
- Reuter, Friederike (1)
- Hopf, Carsten (1)
- Hahn, Udo (1)
- Faessler, Erik (1)
- Lercher, Alexander (1)
- Bergthaler, Andreas (1)
- Schuler, Martin (1)
- Zhu, Jingjing (1)
- Kudo, Takumi (1)
- Figlia, Gianluca (1)
- Viczenczova, Csilla (1)
- Popa, Alexandra M. (1)
- Kosack, Lindsay (1)
- Klavins, Kristaps (1)
- Agerer, Benedikt (1)
- Weller, Michael (1)
- (weitere Einträge vorhanden...)
Publikationen in heiBIB 
- Yanqui-Rivera, Francisco: Glutarate tunes T cell fate / Francisco Yanqui-Rivera & Christiane A. Opitz, 21 August 2023. - 3 S.
In: Nature metabolism, ISSN 2522-5812. 5(2023), 10, Seite 1649-1651
DOI: 10.1038/s42255-023-00878-9
- Opitz, Christiane: The complex biology of aryl hydrocarbon receptor activation in cancer and beyond / Christiane A. Opitz, Pauline Holfelder, Mirja Tamara Prentzell, Saskia Trump, 9 September 2023. - 18 S.
In: Biochemical pharmacology, ISSN 1873-2968. 216(2023), Artikel-ID 115798, Seite 1-18
DOI: 10.1016/j.bcp.2023.115798
- Solvay, Marie: Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes / Marie Solvay, Pauline Holfelder, Simon Klaessens, Luc Pilotte, Vincent Stroobant, Juliette Lamy, Ste… , 2023. - 15 S.
In: Journal for ImmunoTherapy of Cancer, ISSN 2051-1426. 11(2023), 6, Artikel-ID e006728, Seite 1-15
DOI: 10.1136/jitc-2023-006728
- Abu Sammour, Denis: Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging / Denis Abu Sammour, James L. Cairns, Tobias Boskamp, Christian Marsching, Tobias Kessler, Carina Rama… , 01 April 2023. - 15 S.
In: Nature Communications, ISSN 2041-1723. 14(2023) vom: Apr., Artikel-ID 1823, Seite 1-15
DOI: 10.1038/s41467-023-37394-z
- Fülöp, Annabelle: Device-controlled microcondensation for spatially confined on-tissue digests in MALDI imaging of N-glycans / Annabelle Fülöp, Christian Marsching, Frederik Barka, Yasemin Ucal, Pauline Pfänder, Christiane A. O… , 3 November 2022. - 11 S.
In: Pharmaceuticals, ISSN 1424-8247. 15(2022), 11, special issue, Artikel-ID 1356, Seite 1-11
DOI: 10.3390/ph15111356
- Henneberg, Alessa L.: Making liver cancer cells go ARGh! / Alessa L. Henneberg & Christiane A. Opitz, 12 October 2022. - 2 S.
In: The EMBO journal, ISSN 1460-2075. 41(2022), 21, Artikel-ID e112415, Seite 1-2
DOI: 10.15252/embj.2022112415
- Prentzell, Mirja Tamara: cDC1 to cDC2: "Everything I do, Ido1 it for you" / Mirja Tamara Prentzell and Christiane A. Opitz, 14 June 2022. - 4 S.
In: Immunity, ISSN 1097-4180. 55(2022), 6, Seite 967-970
DOI: 10.1016/j.immuni.2022.05.015
- Bakr, Ali: ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition / Ali Bakr, Joschka Hey, Gianluca Sigismondo, Chun-Shan Liu, Ahmed Sadik, Ashish Goyal, Alice Cross, R… , 28 October 2021. - 24 S.
In: Nucleic acids research, ISSN 1362-4962. 49(2021), 20, Seite 11666-11689
DOI: 10.1093/nar/gkab964
- Rehbein, Ulrike: The TSC complex-mTORC1 axis : from lysosomes to stress granules and back / Ulrike Rehbein, Mirja Tamara Prentzell, Marti Cadena Sandoval, Alexander Martin Heberle, Elizabeth P… , 29 October 2021. - 8 S.
In: Frontiers in cell and developmental biology, ISSN 2296-634X. 9(2021), Artikel-ID 751892, Seite 1-8
DOI: 10.3389/fcell.2021.751892
- Panitz, Verena: Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma / Verena Panitz, Saša Končarević, Ahmed Sadik, Dennis Friedel, Tobias Bausbacher, Saskia Trump, Vadim … , 2021.09.03. - 17 S.
In: Theranostics, ISSN 1838-7640. 11(2021), 19, Seite 9217-9233
DOI: 10.7150/thno.60679
- Platten, Michael: Tryptophan metabolism in brain tumors : IDO and beyond / Michael Platten, Mirco Friedrich, Derek A Wainwright, Verena Panitz and Christiane A Opitz, June 2021. - 10 S.
In: Current opinion in immunology, ISSN 1879-0372. 70(2021), Seite 57-66
DOI: 10.1016/j.coi.2021.03.005
- Opitz, Christiane: From anti-aging drugs to cancer therapy : is there a potential for sirtuin activators in gliomas? / Christiane A. Opitz and Sevin Turcan, 2021. - 3 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 1 vom: Jan., Seite 3-5
DOI: 10.1093/neuonc/noaa234
- Prentzell, Mirja Tamara: G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling / Mirja Tamara Prentzell, Ulrike Rehbein, Marti Cadena Sandoval, Ann-Sofie De Meulemeester, Ralf Baume… , 25 January 2021. - 20 S.
In: Cell, ISSN 1097-4172. 184(2021,3), Seite 655-674, e1-e19, 47 Seiten
DOI: 10.1016/j.cell.2020.12.024
- Mohapatra, Soumya Ranjan: Hypoxia routes tryptophan homeostasis towards increased tryptamine production / Soumya R. Mohapatra, Ahmed Sadik, Suraj Sharma, Gernot Poschet, Hagen M. Gegner, Tobias V. Lanz, Phi… , 19 February 2021. - 13 S.
In: Frontiers in immunology, ISSN 1664-3224. 12(2021), Artikel-ID 590532, Seite 1-13
DOI: 10.3389/fimmu.2021.590532
- Keßler, Tobias: Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes / Tobias Kessler, Anne Berberich, Ahmed Sadik, Felix Sahm, Thierry Gorlia, Christoph Meisner, Dirk C. … , 2020. - 13 S.
In: Cancer medicine, ISSN 2045-7634. 9(2020), 22, Seite 8373-8385
DOI: 10.1002/cam4.3447
- Nothdurft, Silke: Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis / Silke Nothdurft, Clotilde Thumser-Henner, Frank Breitenbücher, Ross A. Okimoto, Madeleine Dorsch, Ch… , 19 November 2020. - 12 S.
In: Oncogenesis, ISSN 2157-9024. 9(2020), 11, Seite 1-12
DOI: 10.1038/s41389-020-00286-8
- Lercher, Alexander: Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis / Alexander Lercher, Alexandra M. Popa, Csilla Viczenczova, Lindsay Kosack, Kristaps Klavins, Benedikt… , October 12, 2020. - 22 S.
In: PLoS pathogens, ISSN 1553-7374. 16(2020,10) Artikel-Nummer e1008973, 22 Seiten
DOI: 10.1371/journal.ppat.1008973
- Aslan, Katrin: Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas / Katrin Aslan, Verena Turco, Jens Blobner, Jana K. Sonner, Anna Rita Liuzzi, Nicolás Gonzalo Núñez, D… , 18 February 2020. - 14 S.
In: Nature Communications, ISSN 2041-1723. 11(2020) Artikel-Nummer 931, 14 Seiten
DOI: 10.1038/s41467-020-14642-0
- Kudo, Takumi: Constitutive expression of the immunosuppressive tryptophan dioxygenase TDO2 in glioblastoma is driven by the transcription factor C/EBPβ / Takumi Kudo, Mirja T. Prentzell, Soumya R. Mohapatra, Felix Sahm, Zhongliang Zhao, Ingrid Grummt, Wo… , 14 May 2020. - 9 S.
In: Frontiers in immunology, ISSN 1664-3224. 11(2020) Artikel-Nummer 657, 9 Seiten
DOI: 10.3389/fimmu.2020.00657
- Sadik, Ahmed: IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression / Ahmed Sadik, Luis F. Somarribas Patterson, Selcen Öztürk, Soumya R. Mohapatra, Verena Panitz, Philip… , August 19, 2020. - 54 S.
In: Cell, ISSN 1097-4172. 182(2020), 5, Seite 1252-1270.e34
DOI: 10.1016/j.cell.2020.07.038
- Heberle, Alexander Martin: The PI3K and MAPK/p38 pathways control stress granule assembly in a hierarchical manner / Alexander Martin Heberle, Patricia Razquin Navas, Miriam Langelaar-Makkinje, Katharina Kasack, Ahmed… , 2019
In: Life science alliance, ISSN 2575-1077. Volume 2 (2019), number 2, article e201800257, Seite 1-22, 22 Seiten
DOI: 10.26508/lsa.201800257
- Kaul, Nathalie-Christin: Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism / Nathalie-Christin Kaul, Soumya R. Mohapatra, Isabell Adam, Christine Tucher, Theresa Tretter, Christ… , 2020. - 11 S.
In: Rheumatology, ISSN 1462-0332. 59(2020), 5, Seite 1148-1158
DOI: 10.1093/rheumatology/kez587
- Mohapatra, Soumya Ranjan: Hypoxia inducible factor 1α inhibits the expression of immunosuppressive tryptophan-2,3-dioxygenase in glioblastoma / Soumya R. Mohapatra, Ahmed Sadik, Lars-Oliver Tykocinski, Jørn Dietze, Gernot Poschet, Ines Heiland … , 04 December 2019. - 13 S.
In: Frontiers in immunology, ISSN 1664-3224. 10(2019) Artikel-Nummer 2762, 13 Seiten
DOI: 10.3389/fimmu.2019.02762
- Platten, Michael: Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond / Michael Platten, Ellen A.A. Nollen, Ute F. Röhrig, Francesca Fallarino and Christiane A. Opitz, 13 February 2019. - 23 S.
In: Nature reviews, ISSN 1474-1784. 18(2019), 5, Seite 379-401
DOI: 10.1038/s41573-019-0016-5
- Opitz, Christiane: The therapeutic potential of targeting tryptophan catabolism in cancer / Christiane A. Opitz, Luis F. Somarribas Patterson, Soumya R. Mohapatra, Dyah L. Dewi, Ahmed Sadik, M… , 2020. - 15 S.
In: British journal of cancer, ISSN 1532-1827. 122(2020), 1, Seite 30-44
DOI: 10.1038/s41416-019-0664-6
- Sonner, Jana K.: Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology / Jana K. Sonner, Melanie Keil, Maren Falk-Paulsen, Neha Mishra, Ateequr Rehman, Magdalena Kramer, Kat… , 25 October 2019. - 14 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Artikel-Nummer 4877, 14 Seiten
DOI: 10.1038/s41467-019-12776-4
- Rabe, Jan-Hinrich: Fourier transform infrared microscopy enables guidance of automated mass spectrometry imaging to predefined tissue morphologies / Jan-Hinrich Rabe, Denis A. Sammour, Sandra Schulz, Bogdan Munteanu, Martina Ott, Katharina Ochs, Pet… , 10 January 2018. - 11 S.
In: Scientific reports, ISSN 2045-2322. 8(2018) Artikel-Nummer 313, 11 Seiten
DOI: 10.1038/s41598-017-18477-6
- Adam, Isabell: Upregulation of tryptophanyl-tRNA synthethase adapts human cancer cells to nutritional stress caused by tryptophan degradation / Isabell Adam, Dyah L. Dewi, Joram Mooiweer, Ahmed Sadik, Soumya R. Mohapatra, Bianca Berdel, Melanie… , 05 Sep 2018. - 14 S.
In: OncoImmunology, ISSN 2162-402X. 7(2018,12) Artikel-Nummer e1486353, 14 Seiten
DOI: 10.1080/2162402X.2018.1486353
- Keßler, Tobias: Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation / Tobias Kessler, Felix Sahm, Ahmed Sadik, Damian Stichel, Anne Hertenstein, Guido Reifenberger, Angel… , 2018. - 13 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 3, Seite 367-379
DOI: 10.1093/neuonc/nox160
- Tykocinski, Lars-Oliver: Synovial fibroblasts selectively suppress Th1 cell responses through IDO1-mediated tryptophan catabolism / Lars-Oliver Tykocinski, Anna M. Lauffer, Antonia Bohnen, Nathalie-Christin Kaul, Stefan Krienke, The… , 6 March 2017. - 9 S.
In: The journal of immunology, ISSN 1550-6606. 198(2017), 8, Seite 3109-3117
DOI: 10.4049/jimmunol.1600600
- Dewi, Dyah: Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer / Dyah L. Dewi, Soumya R. Mohapatra, Saioa Blanco Cabañes, Isabell Adam, Luis F. Somarribas Patterson,… , 07 Feb 2017. - 12 S.
In: OncoImmunology, ISSN 2162-402X. 6(2017,2) Artikel-Nummer e1274477, 12 Seiten
DOI: 10.1080/2162402X.2016.1274477
- Lanz, Tobias: Suppression of Th1 differentiation by tryptophan supplementation in vivo / Tobias V. Lanz, Simon Becker, Soumya R. Mohapatra, Christiane A. Opitz, Wolfgang Wick, Michael Platt… , 18 April 2017. - 7 S.
In: Amino acids, ISSN 1438-2199. 49(2017), 7, Seite 1169-1175
DOI: 10.1007/s00726-017-2415-4
- Seddigh, Pegah: Quantitative analysis of proteome modulations in alveolar epithelial type II cells in response to pulmonary aspergillus fumigatus infection / Pegah Seddigh, Thilo Bracht, Válerie Molinier-Frenkel, Flavia Castellano, Olaf Kniemeyer, Marc Schus… . - 15 S.
In: Molecular & cellular proteomics, ISSN 1535-9484. 16(2017), 12, S. 2184-2198
DOI: 10.1074/mcp.RA117.000072
- Lanz, Tobias: Tryptophan-2,3-Dioxygenase (TDO) deficiency is associated with subclinical neuroprotection in a mouse model of multiple sclerosis / Tobias V. Lanz, Sarah K. Williams, Aleksandar Stojic, Simeon Iwantscheff, Jana K. Sonner, Carl Grabi… , 24 January 2017
In: Scientific reports, ISSN 2045-2322. 7(2017) Artikel-Nummer 41271, 13 Seiten
DOI: 10.1038/srep41271
- Sonner, Jana K.: The stress kinase GCN2 does not mediate suppression of antitumor T cell responses by tryptophan catabolism in experimental melanomas / Jana K. Sonner, Katrin Deumelandt, Martina Ott, Carina M. Thomé, Katharina J. Rauschenbach, Sandra S… , 29 Nov 2016. - 11 S.
In: OncoImmunology, ISSN 2162-402X. 5(2016,12) Artikel-Nummer e1240858, 11 Seiten
DOI: 10.1080/2162402X.2016.1240858
- Sahm, Katharina: Tryptophan-2,3-dioxygenase is regulated by prostaglandin E2 in malignant glioma via a positive signaling loop involving prostaglandin E receptor-4 / Katharina Ochs, Martina Ott, Katharina J. Rauschenbach, Katrin Deumelandt, Felix Sahm, Christiane A.… , 2016. - 13 S.
In: Journal of neurochemistry, ISSN 1471-4159. 136(2016), 6, Seite 1142-1154
DOI: 10.1111/jnc.13503
- Ott, Martina: Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway / Martina Ott, Ulrike M. Litzenburger, Katharina J. Rauschenbach, Lukas Bunse, Katharina Ochs, Felix S… , January 2015. - 13 S.
In: Glia, ISSN 1098-1136. 63(2015), 1, Seite 78-90
DOI: 10.1002/glia.22734
- Platten, Michael: Microenvironmental clues for glioma immunotherapy / Michael Platten, Katharina Ochs, Dieter Lemke, Christiane Opitz, Wolfgang Wick
In: Current neurology and neuroscience reports, ISSN 1534-6293. 14(2014,4) Artikel-Nummer 440, 10 Seiten
DOI: 10.1007/s11910-014-0440-1
- Litzenburger, Ulrike: Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR / Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Ma… , 20 January 2014. - 14 S.
In: OncoTarget, ISSN 1949-2553. 5(2014), 4, Seite 1038-1051
DOI: 10.18632/oncotarget.1637
- Sahm, Felix: The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress / Felix Sahm, Iris Oezen, Christiane A. Opitz, Bernhard Radlwimmer, Andreas von Deimling, Tilman Ahren… , April 2, 2013. - 10 S.
In: Cancer research, ISSN 1538-7445. 73(2013), 11 vom: Juni, Seite 3225-3234
DOI: 10.1158/0008-5472.CAN-12-3831
- Sahm, Katharina: Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma / Katharina Ochs, Felix Sahm, Christiane A. Opitz, Tobias V. Lanz, Iris Oezen, Pierre-Olivier Couraud,… , 20 September 2013. - 11 S.
In: Journal of neuroimmunology, ISSN 1872-8421. 265(2013), 1/2, Seite 106-116
DOI: 10.1016/j.jneuroim.2013.09.011
- Lanz, Tobias: Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis / Tobias V. Lanz, Simon Becker, Matthias Osswald, Stefan Bittner, Michael K. Schuhmann, Christiane A. … , August 19, 2013. - 6 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 110(2013), 36 vom: Sept., Seite 14735-14740
DOI: 10.1073/pnas.1302569110
- Platten, Michael: The aryl hydrocarbon receptor as a promoter of malignant glioma / Michael Platten, Christiane Opitz, Wolfgang Wick. - 2 S.
In: Cell cycle, ISSN 1551-4005. 11(2012), 4, S. 643-644
DOI: 10.4161/cc.11.4.19357
- Opitz, Christiane: An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor / Christiane A. Opitz, Ulrike M. Litzenburger, Felix Sahm, Martina Ott, Isabel Tritschler, Saskia Trum… , 05 October 2011. - 7 S.
In: Nature, ISSN 1476-4687. 478(2011), 7368, Seite 197-203
DOI: 10.1038/nature10491
- Opitz, Christiane: The Indoleamine-2,3-Dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells / Christiane A. Opitz, Ulrike M. Litzenburger, Uta Opitz, Felix Sahm, Katharina Ochs, Christian Lutz, … , May 20, 2011. - 11 S.
In: PLOS ONE, ISSN 1932-6203. 6(2011), 5 vom: Mai, Artikel-ID e19823, Seite 1-11
DOI: 10.1371/journal.pone.0019823
- Berberich, Anne: Suppression of human CD4+ T cell activation by 3,4-dimethoxycinnamonyl-anthranilic acid (tranilast) is mediated by CXCL9 and CXCL10 / Anne Hertenstein, Theresa Schumacher, Ulrike Litzenburger, Christiane A. Opitz, Christine S. Falk, T… , [15 September 2011]. - 10 S. : Illustrationen
In: Biochemical pharmacology, ISSN 1873-2968. 82(2011), 6 vom: Sept., Seite 632-641
DOI: 10.1016/j.bcp.2011.06.013
- Lanz, Tobias: Mouse mesenchymal stem cells suppress antigen-specific TH cell immunity independent of indoleamine 2,3-dioxygenase 1 (IDO1) / Tobias V. Lanz, Christiane A. Opitz, Peggy P. Ho, Ankur Agrawal, Christian Lutz, Michael Weller, And… , May 2010. - 12 S.
In: Stem Cells and Development, ISSN 1557-8534. 19(2010), 5 vom: Mai, Seite 657-668
DOI: 10.1089/scd.2009.0385
- Platten, Michael: Painful neuropathy due to intraneural leukemic spread in a patient with acute myeloid leukemia / M. Platten, C.A. Opitz, P. Kohlhof, U. Hegenbart, A.D. Ho, and W. Wick, Heidelberg, Germany, August 13, 2007. - 1 S. : Illustrationen
In: Neurology, ISSN 1526-632X. 69(2007), 7, Seite 707
DOI: 10.1212/01.wnl.0000275547.39894.a6
- Opitz, Christiane: Die Verkürzungsdynamik der Titinfeder in Myofibrillen des Humanherzens / vorgelegt von Christiane Agnes Opitz, 2006. - 84 Bl. : Ill., graph. Darst.
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