heiBIB: Heilig, Christoph E.

Heilig, Christoph E. Dr. med.Universität HeidelbergHeidelberg

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englisch (31)
deutsch (1)

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Publikationen in heiBIB

Scherr, Anna-Lena: Etiology-independent activation of the LTβ-LTβR-RELB axis drives aggressiveness and predicts poor prognosis in HCC / Anna-Lena Scherr, Luisa Nader, Kaiyu Xu, Christin Elssner, Dirk A. Ridder, Federico Nichetti, Manuel… , August 2024. - 17 S. : Illustrationen
In: Hepatology, ISSN 1527-3350. 80(2024), 2, Seite 278-294
DOI: 10.1097/HEP.0000000000000657
Ellermann, Julia: Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions / Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Caraz… , 02 January 2024. - 17 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 51, Seite 1-17
DOI: 10.1038/s41467-023-44360-2
Lauinger, Manuel: BRAFΔβ3-αC in-frame deletion mutants differ in their dimerization propensity, HSP90 dependence, and druggability / Manuel Lauinger, Daniel Christen, Rhena F. U. Klar, Carole Roubaty, Christoph E. Heilig, Michael Stu… , 2023. - 22 S. : Illustrationen
In: Science advances, ISSN 2375-2548. 9(2023), 35, Artikel-ID eade7486, Seite 1-22
DOI: 10.1126/sciadv.ade7486
Horak, Peter: Assigning evidence to actionability : an introduction to variant interpretation in precision cancer medicine / Peter Horak, Jonas Leichsenring, Hannah Goldschmid, Simon Kreutzfeldt, Daniel Kazdal, Veronica Telea… , June 2022. - 11 S.
In: Genes, chromosomes & cancer, ISSN 1098-2264. 61(2022), 6, 6, Seite 303-313
DOI: 10.1002/gcc.22987
Jahn, Arne: Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers / A. Jahn, A. Rump, T.J. Widmann, C. Heining, P. Horak, B. Hutter, N. Paramasivam, S. Uhrig, L. Gieldo… , 18 August 2022. - 14 S.
In: Annals of oncology, ISSN 1569-8041. 33(2022), 11, Seite 1186-1199
DOI: 10.1016/j.annonc.2022.07.008
Heilig, Christoph E.: Gene expression-based prediction of pazopanib efficacy in sarcoma / Christoph E. Heilig, Andreas Laßmann, Sadaf S. Mughal, Andreas Mock, Sebastian Pirmann, Veronica Tel… , 25 June 2022. - 12 S.
In: European journal of cancer, ISSN 1879-0852. 172(2022), Seite 107-118
DOI: 10.1016/j.ejca.2022.05.025
Möhrmann, Lino: Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity / Lino Möhrmann, Maximilian Werner, Małgorzata Oleś, Andreas Mock, Sebastian Uhrig, Arne Jahn, Simon K… , 02 August 2022. - 15 S.
In: Nature Communications, ISSN 2041-1723. 13(2022), Artikel-ID 4485, Seite 1-15
DOI: 10.1038/s41467-022-31866-4
Sobol, Benjamin: Specific targeting of antiapoptotic Bcl-2 proteins as a radiosensitizing approach in solid tumors / Benjamin Sobol, Osama Azzam Nieto, Emily Lara Eberlein, Anna-Lena Scherr, Lars Ismail, Annika Kessle… , 16 July 2022. - 13 S.
In: International journal of molecular sciences, ISSN 1422-0067. 23(2022), 14, Artikel-ID 7850, Seite 1-13
DOI: 10.3390/ijms23147850
Hübschmann, Daniel: Analysis of mutational signatures with yet another package for signature analysis / Daniel Hübschmann, Lea Jopp-Saile, Carolin Andresen, Stephen Krämer, Zuguang Gu, Christoph E. Heilig… , May 2021. - 18 S.
In: Genes, chromosomes & cancer, ISSN 1098-2264. 60(2021), 5, special issue vom: Mai, Seite 314-331
DOI: 10.1002/gcc.22918
Kölsche, Christian: Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature / Christian Koelsche, Jamal K. Benhamida, Felix K. F. Kommoss, Damian Stichel, David T. W. Jones, Stef… , December 2021. - 8 S.
In: Modern pathology, ISSN 1530-0285. 34(2021), 12 vom: Dez., Seite 2122-2129
DOI: 10.1038/s41379-021-00874-y
Heilig, Christoph E.: Rationale and design of the CRAFT (Continuous ReAssessment with Flexible ExTension in Rare Malignancies) multicenter phase II trial / C.E. Heilig, P. Horak, S. Kreutzfeldt, V. Teleanu, A. Mock, M. Renner, I.A. Bhatti, B. Hutter, J. Hü… , 20 November 2021. - 5 S.
In: ESMO open, ISSN 2059-7029. 6(2021), 6, Artikel-ID 100310, Seite 1-5
DOI: 10.1016/j.esmoop.2021.100310
Jaramillo Segura, Sonia: Ruxolitinib is effective in the treatment of a patient with refractory T-ALL / Sonia Jaramillo, Hannah Hennemann, Peter Horak, Veronica Teleanu, Christoph E. Heilig, Barbara Hutte… , 2021. - 4 S.
In: eJHaem, ISSN 2688-6146. 2(2021), 1, Seite 139-142
DOI: 10.1002/jha2.143
Horak, Peter: Comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers / Peter Horak, Christoph Heining, Simon Kreutzfeldt, Barbara Hutter, Andreas Mock, Jennifer Hullein, M… , June 10, 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 11, Seite 2780-2795
DOI: 10.1158/2159-8290.CD-21-0126
Kölsche, Christian: Sarcoma classification by DNA methylation profiling / Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam… , 21 January 2021. - 10 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 498, Seite 1-10
DOI: 10.1038/s41467-020-20603-4
McConnell, Lauren: Detection of structural variants in circulating cell-free DNA from sarcoma patients using next generation sequencing / Lauren Mc Connell, Jana Gazdova, Katja Beck, Shambhavi Srivastava, Louise Harewood, JP Stewart, Dani… , 3 December 2020. - 9 S.
In: Cancer research, ISSN 1538-7445. 12(2020), 12, Artikel-ID 3627, Seite 1-9
DOI: 10.3390/cancers12123627
Heilig, Christoph E.: Haematopoietic stem cell transplantation in adult soft-tissue sarcoma : an analysis from the European Society for Blood and Marrow Transplantation / Christoph E. Heilig, Manuela Badoglio, Myriam Labopin, Stefan Fröhling, Simona Secondino, Jürgen Hei… , 23 October 2020. - 8 S.
In: ESMO open, ISSN 2059-7029. 5(2020), 5, Artikel-ID e000860, Seite 1-8
DOI: 10.1136/esmoopen-2020-000860
Kommoss, Felix: Endometrial stromal sarcomas with BCOR‐rearrangement harbor MDM2 amplifications / Felix KF Kommoss, Kenneth TE Chang, Damian Stichel, Ana Banito, David TW Jones, Christoph E. Heilig,… , 30 April 2020. - 7 S.
In: The journal of pathology: clinical research, ISSN 2056-4538. 6(2020), 3, Seite 178-184
DOI: 10.1002/cjp2.165
Scherr, Anna-Lena: Identification of BCL-XL as highly active survival factor and promising therapeutic target in colorectal cancer / Anna-Lena Scherr, Andreas Mock, Georg Gdynia, Nathalie Schmitt, Christoph E. Heilig, Felix Korell, P… , 17 October 2020. - 16 S.
In: Cell death & disease, ISSN 2041-4889. 11(2020), 10, Seite 1-16
DOI: 10.1038/s41419-020-03092-7
Voronina, Natalia: The landscape of chromothripsis across adult cancer types / Natalia Voronina, John K.L. Wong, Daniel Hübschmann, Mario Hlevnjak, Sebastian Uhrig, Christoph E. H… , 08 May 2020. - 13 S.
In: Nature Communications, ISSN 2041-1723. 11(2020) Artikel-Nummer 2320, 13 Seiten
DOI: 10.1038/s41467-020-16134-7
Mock, Andreas: Community-driven development of a modified progression-free survival ratio for precision oncology / Andreas Mock, Christoph E Heilig, Simon Kreutzfeldt, Daniel Huebschmann, Christoph Heining, Evelin S… , November 13, 2019. - 6 S. : Diagramme
In: ESMO open, ISSN 2059-7029. 4(2019) Artikel-Nummer e00058, 6 Seiten
DOI: 10.1136/esmoopen-2019-000583
Leichsenring, Jonas: Variant classification in precision oncology / Jonas Leichsenring, Peter Horak, Simon Kreutzfeldt, Christoph Heining, Petros Christopoulos, Anna-Le… , 22 April 2019. - 15 S.
In: International journal of cancer, ISSN 1097-0215. 145(2019), 11, Seite 2996-3010
DOI: 10.1002/ijc.32358
Gröschel, Stefan: Defective homologous recombination DNA repair as therapeutic target in advanced chordoma / Stefan Gröschel, Daniel Hübschmann, Francesco Raimondi, Peter Horak, Gregor Warsow, Martina Fröhlich… , 09 April, 2019. - 9 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Artikel-Nummer 1635, 9 Seiten
DOI: 10.1038/s41467-019-09633-9
Chudasama, Priya: Integrative genomic and transcriptomic analysis of leiomyosarcoma / Priya Chudasama, Sadaf S. Mughal, Mathijs A. Sanders, Daniel Hübschmann, Inn Chung, Katharina I. Dee… , 10 January 2018. - 15 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 144, 15 Seiten
DOI: 10.1038/s41467-017-02602-0
Bochtler, Tilmann: Marker chromosomes can arise from chromothripsis and predict adverse prognosis in acute myeloid leukemia / Tilmann Bochtler, Martin Granzow, Friedrich Stölzel, Christina Kunz, Brigitte Mohr, Mutlu Kartal-Kae… , January 24, 2017. - 10 S.
In: Blood, ISSN 1528-0020. 129(2017), 10, Seite 1333-1342
DOI: 10.1182/blood-2016-09-738161
Burhenne, Jürgen: Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients / Jürgen Burhenne, Lu Liu, Christoph E. Heilig, Andreas D. Meid, Margarete Leisen, Thomas Schmitt, Ber… , 13 June 2017. - 7 S.
In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 80(2017), 2, Seite 433-439
DOI: 10.1007/s00280-017-3357-y
Kriegsmann, Katharina: Successful collection of peripheral blood stem cells upon VIDE chemomobilization in sarcoma patients / Katharina Kriegsmann, Christoph Heilig, Martin Cremer, Philipp Novotny, Mark Kriegsmann, Thomas Bruc… , 2017. - 6 S.
In: European journal of haematology, ISSN 1600-0609. 99(2017), 5, Seite 459-464
DOI: 10.1111/ejh.12960
Kriegsmann, Katharina: Bone marrow harvesting of allogeneic donors in an outpatient setting : a single-center experience / Katharina Lisenko, Peter Stadtherr, Thomas Bruckner, Petra Pavel, Christoph E. Heilig, Anita Schmitt… , 2016. - 5 S.
In: Biology of blood and marrow transplantation, ISSN 1523-6536. 22(2016), 3, Seite 470-474
DOI: 10.1016/j.bbmt.2015.10.025
Schmitt, Thomas: Vorinostat in refractory soft tissue sarcomas : results of a multi-centre phase II trial of the German Soft Tissue Sarcoma and Bone Tumour Working Group (AIO) / Thomas Schmitt, Regine Mayer-Steinacker, Frank Mayer, Viktor Grünwald, Jochen Schütte, Jörg T. Hartm… , September 2016. - 9 S.
In: European journal of cancer, ISSN 1879-0852. 64(2016), Seite 74-82
DOI: 10.1016/j.ejca.2016.05.018
Balß, Jörg: Pretreatment d -2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia / J. Balss, C. Thiede, T. Bochtler, J.G. Okun, M. Saadati, A. Benner, S. Pusch, G. Ehninger, M. Schaic… , 2016. - 7 S.
In: Leukemia, ISSN 1476-5551. 30(2016), 4, Seite 782-788
DOI: 10.1038/leu.2015.317
Bochtler, Tilmann: Clonal heterogeneity as detected by metaphase karyotyping is an indicator of poor prognosis in acute myeloid leukemia / Tilmann Bochtler, Friedrich Stölzel, Christoph E. Heilig, Christina Kunz, Brigitte Mohr, Anna Jauch,… , September 23, 2013. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 31(2013), 31, Seite 3898-3905
DOI: 10.1200/JCO.2013.50.7921
Heilig, Christoph E.: Chromosomal instability correlates with poor outcome in patients with myelodysplastic syndromes irrespectively of the cytogenetic risk group / Christoph E. Heilig, Harald Löffler, Ulrich Mahlknecht, Johannes W.G. Janssen, Anthony D. Ho, Anna J… , [April 2010]. - 8 S. : Illustrationen
In: Journal of cellular and molecular medicine, ISSN 1582-4934. 14(2010), 4 vom: Apr., Seite 895-902
DOI: 10.1111/j.1582-4934.2009.00905.x
Heilig, Christoph E.: Über chromosomale Instabilität myeloischer Neoplasien / vorgelegt von Christoph Emanuel Heilig, 2009 [ersch.] 2010. - V, 187 Bl. : Ill., graph. Darst.

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