
Wiedmann, Felix Tobias PD; Dr. med.Universität HeidelbergHeidelberg
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Publications in heiBIB 
- Babin-Ebell Gonçalves, Anna: A perfusion-independent high-throughput method to isolate liver sinusoidal endothelial cells / Anna Babin-Ebell Gonçalves, Yifang Mao, Tinja Baljkas, Felix Wiedmann, Larissa Eis, Franziska Pilz, … , 8. Januar 2025. - 10 S.
In: Communications biology, ISSN 2399-3642. 8(2025), 1, Artikel-ID 22, Seite 1-10
DOI: 10.1038/s42003-025-07458-5
- Wiedmann, Felix Tobias: SARS-CoV-2 ORF 3a-mediated currents are inhibited by antiarrhythmic drugs / Felix Wiedmann, Emika Boondej, Megan Stanifer, Amelie Paasche, Manuel Kraft, Merten Prüser, Timon Se… , October 2024. - 16 S. : Illustrationen
In: Europace, ISSN 1532-2092. 26(2024), 10, Artikel-ID euae252, Seite 1-16
DOI: 10.1093/europace/euae252
- Wiedmann, Felix Tobias: Novel drug therapies for atrial fibrillation / Felix Wiedmann, Constanze Schmidt, May 2024. - 2 S.
In: Nature reviews, ISSN 1759-5010. 21(2024), 5, Seite 275-276
DOI: 10.1038/s41569-024-01004-2
- Prüser, Merten: Comment on: ‘Physiological and pathophysiological roles of the KCNK3 potassium channel in the pulmonary circulation and the heart’ by Saint-Martin Willer et al. / Merten Prüser, Felix Wiedmann, Constanze Schmidt, 1 May 2024. - 2 S.
In: The journal of physiology, ISSN 1469-7793. 602(2024), 9 vom: Mai, Seite 2141-2142
DOI: 10.1113/JP286611
- Hegner, Philipp: Inhibition of the potassium channel TASK-1 in human atria to reduce arrhythmogenesis / Philipp Hegner, MD, Manuel Schuh, Felix Wiedmann, MD, Daniele Camboni, MD, Christof Schmid, MD, Lars… , September 2024. - 3 S. : Illustrationen
In: Heart rhythm, ISSN 1556-3871. 21(2024), 9 vom: Sept., Seite 1743-1745
DOI: 10.1016/j.hrthm.2024.03.1809
- Wiedmann, Felix Tobias: A porcine large animal model of radiofrequency ablation-induced left bundle branch block / Felix Wiedmann, Max Jamros, Valerie Herlt, Amelie Paasche, Manuel Kraft, Moritz Beck, Merten Prüser,… , 19 April 2024. - 14 S. : Illustrationen
In: Frontiers in physiology, ISSN 1664-042X. 15(2024) vom: Apr., Artikel-ID 1385277, Seite 1-14
DOI: 10.3389/fphys.2024.1385277
- Paasche, Amelie: Acute antiarrhythmic effects of SGLT2 inhibitors-dapagliflozin lowers the excitability of atrial cardiomyocytes / Amelie Paasche, Felix Wiedmann, Manuel Kraft, Fitzwilliam Seibertz, Valerie Herlt, Pablo L. Blochber… , 03 January 2024. - 20 S.
In: Basic research in cardiology, ISSN 1435-1803. 119(2024), 1, Seite 93-112
DOI: 10.1007/s00395-023-01022-0
- Wiedmann, Felix Tobias: Activation of neurokinin-III receptors modulates human atrial TASK-1 currents / Felix Wiedmann, Amelie Paasche, Jendrik Nietfeld, Manuel Kraft, Anna L. Meyer, Gregor Warnecke, Matt… , November 2023. - 11 S.
In: Journal of molecular and cellular cardiology, ISSN 1095-8584. 184(2023), Seite 26-36
DOI: 10.1016/j.yjmcc.2023.09.010
- Wiedmann, Felix Tobias: Single beta-blocker or combined amiodarone therapy in implantable cardioverter-defibrillator and cardiac resynchronization therapy - defibrillator patients : insights from the German DEVICE registry / Felix Wiedmann, Hüseyin Ince, Christoph Stellbrink, Thomas Kleemann, Lars Eckardt, Johannes Brachman… , 28 March 2023. - 9 S.
In: Heart rhythm, ISSN 1556-3871. 20(2023), 4 vom: März, Seite 501-509
DOI: 10.1016/j.hrthm.2022.12.009
- Wiedmann, Felix Tobias: Die Inhibition atrialer TASK-1 Kaliumkanäle als neuer Ansatz in der Vorhofflimmertherapie / vorgelegt von Dr. med. Felix Wiedmann. -
Heidelberg, 2022. - 1 Band (verschiedene Seitenzählungen) : Illustrationen, Diagramme
- Kraft, Manuel: Simultaneous quantification and pharmacokinetic characterization of doxapram and 2-ketodoxapram in porcine plasma and brain tissue / Manuel Kraft, Kathrin I. Foerster, Felix Wiedmann, Max Sauter, Amelie Paasche, Pablo L. Blochberger,… , 31 March 2022. - 13 S.
In: Pharmaceutics, ISSN 1999-4923. 14(2022), 4 vom: Apr., Artikel-ID 762, Seite 1-13
DOI: 10.3390/pharmaceutics14040762
- Wiedmann, Felix Tobias: MicroRNAs regulate TASK‐1 and are linked to myocardial dilatation in atrial fibrillation / Felix Wiedmann, MD; Manuel Kraft, MSc; Stefan Kallenberger, MD, PhD; Antonius Büscher, MD; Amelie P… , 18 Mar 2022. - 16 S.
In: Journal of the American Heart Association, ISSN 2047-9980. 11(2022), 7, Artikel-ID e023472, Seite 1-16
DOI: 10.1161/JAHA.121.023472
- Wiedmann, Felix Tobias: Two-pore-domain potassium (K2P-) channels : cardiac expression patterns and disease-specific remodelling processes / Felix Wiedmann, Norbert Frey and Constanze Schmidt, 27 October 2021. - 46 S.
In: Cells, ISSN 2073-4409. 10(2021), 11, special issue, Artikel-ID 2914, Seite 1-46
DOI: 10.3390/cells10112914
- Schmidt, Constanze: Prospective multicentric validation of a novel prediction model for paroxysmal atrial fibrillation / Constanze Schmidt, Sebastian Benda, Patricia Kraft, Felix Wiedmann, Sven Pleger, Antonius Büscher, D… , 2021. - 9 S.
In: Clinical research in cardiology, ISSN 1861-0692. 110(2021), 6, Seite 868-876
DOI: 10.1007/s00392-020-01773-z
- Darkow, Elisa: Small conductance Ca2+ -activated K+ (SK) channel mRNA expression in human atrial and ventricular tissue : comparison between donor, atrial fibrillation and heart failure tissue / Elisa Darkow, Thong T. Nguyen, Marina Stolina, Fabian A. Kari, Constanze Schmidt, Felix Wiedmann, Is… , 01 April 2021. - 16 S.
In: Frontiers in physiology, ISSN 1664-042X. 12(2021), Artikel-ID 650964, Seite 1-16
DOI: 10.3389/fphys.2021.650964
- Kraft, Manuel: Current drug treatment strategies for atrial fibrillation and TASK-1 inhibition as an emerging novel therapy option / Manuel Kraft, Antonius Büscher, Felix Wiedmann, Yannick L’hoste, Walter E. Haefeli, Norbert Frey, Hu… , 04 March 2021. - 21 S.
In: Frontiers in pharmacology, ISSN 1663-9812. 12(2021) vom: 4. März, Artikel-ID 638445
DOI: 10.3389/fphar.2021.638445
- Wiedmann, Felix Tobias: The experimental TASK-1 Potassium Channel Inhibitor A293 can be employed for rhythm control of persistent atrial fibrillation in a translational large animal model / Felix Wiedmann, Christoph Beyersdorf, Xiao-Bo Zhou, Manuel Kraft, Kathrin I. Foerster, Ibrahim El-Ba… , 21 January 2021. - 13 S.
In: Frontiers in physiology, ISSN 1664-042X. 11(2021) Artikel-Nummer 629421, 13 Seiten
DOI: 10.3389/fphys.2020.629421
- Wiedmann, Felix Tobias: Electrophysiological effects of non-vitamin K antagonist oral anticoagulants on atrial repolarizing potassium channels / Felix Wiedmann, Daniel Schlund, Manuel Kraft, Jendrik Nietfeld, Hugo A Katus, Constanze Schmidt, and… , 17 July 2020. - 10 S.
In: Europace, ISSN 1532-2092. 22(2020), 9, Seite 1409-1418
DOI: 10.1093/europace/euaa129
- Wiedmann, Felix Tobias: Mechanosensitive TREK-1 two-pore-domain potassium (K2P) channels in the cardiovascular system / Felix Wiedmann, Susanne Rinné, Birgit Donner, Niels Decher, Hugo A. Katus, Constanze Schmidt, 2021. - 10 S.
In: Progress in biophysics & molecular biology, ISSN 1873-1732. 159(2021), Seite 126-135
DOI: 10.1016/j.pbiomolbio.2020.05.007
- Wiedmann, Felix Tobias: Pharmacologic TWIK‐related acid‐sensitive K+ channel (TASK‐1) potassium channel Inhibitor A293 facilitates acute cardioversion of paroxysmal atrial fibrillation in a porcine large animal model / Felix Wiedmann, MD; Christoph Beyersdorf, BSc; Xiaobo Zhou, MD; Antonius Büscher, MD; Manuel Kraft, … , 9 May 2020
In: Journal of the American Heart Association, ISSN 2047-9980. 9(2020,10) Artikel-Nummer e015751, 16 Seiten
DOI: 10.1161/JAHA.119.015751
- Wiedmann, Felix Tobias: Identification of the A293 (AVE1231) binding site in the cardiac two-pore-domain potassium channel TASK-1 : a common low affinity attiarrhythmic drug binding site / Felix Wiedmann, Aytug K. Kiper, Mauricio Bedoya, Antonius Ratte, Susanne Rinné, Manuel Kraft, Maximi… , 19 April 2019. - 13 S.
In: Cellular physiology and biochemistry, ISSN 1421-9778. 52(2019), 5, Seite 1223-1235
DOI: 10.33594/000000083
- Wiedmann, Felix Tobias: N-glycosylation of TREK-1/hK2P2.1 : two-pore-domain potassium (K2P) channels / Felix Wiedmann, Daniel Schlund, Francisco Faustino, Manuel Kraft, Antonius Ratte, Dierk Thomas, Hugo… , 20 October 2019. - 18 S.
In: International journal of molecular sciences, ISSN 1422-0067. 20(2019,20) Artikel-Nummer 5193, 18 Seiten
DOI: 10.3390/ijms20205193
- Ratte, Antonius: Antiarrhythmic properties of ranolazine : inhibition of atrial fibrillation associated TASK-1 potassium channels / Antonius Ratte, Felix Wiedmann, Manuel Kraft, Hugo A. Katus and Constanze Schmidt, 26 November 2019. - 13 S.
In: Frontiers in pharmacology, ISSN 1663-9812. 10(2019) Artikel-Nummer 1367, 13 Seiten
DOI: 10.3389/fphar.2019.01367
- Schmidt, Constanze: Genetic ablation of TASK-1 (tandem of P domains in a weak inward rectifying K+ channel-related acid-sensitive K+ channel-1) (K2P3.1) K+ channels suppresses atrial fibrillation and prevents electrical remodeling / Constanze Schmidt, MD, Felix Wiedmann, MD, Christoph Beyersdorf, BS, Zhi-han Zhao, MSc, Ibrahim El-… , September 13, 2019. - 10 S.
In: Circulation, ISSN 1941-3084. 12(2019,1) Artikel-Nummer e007465, 10 Seiten
DOI: 10.1161/CIRCEP.119.007465
- Wiedmann, Felix Tobias: N-glycosylation-dependent regulation of hK2P17.1 currents / Felix Wiedmann, Daniel Schlund, Niels Voigt, Antonius Ratte, Manuel Kraft, Hugo A. Katus, Constanze … , 30 May 2019. - 12 S.
In: Molecular biology of the cell, ISSN 1939-4586. 30(2019), 12, Seite 1425-1436
DOI: 10.1091/mbc.E18-10-0687
- Schmidt, Constanze: New targets for old drugs : cardiac glycosides inhibit atrial-specific K2P3.1 (TASK-1) channels / Constanze Schmidt, Felix Wiedmann, Anne-Rike Gaubatz, Antonius Ratte, Hugo A. Katus and Dierk Thomas, June2018. - 10 S.
In: The journal of pharmacology and experimental therapeutics, ISSN 1521-0103. 365(2018), 3, Seite 614-623
DOI: 10.1124/jpet.118.247692
- Schmidt, Constanze: Reduced Na+ current in native cardiomyocytes of a Brugada Syndrome patient associated with β-2-syntrophin mutation / Constanze Schmidt, MD, Felix Wiedmann, MD, Ibrahim El-Battrawy, MD, Markus Fritz, MD, Antonius Ratte… , Nov 2018. - 3 S.
In: Circulation, ISSN 2574-8300. 11 (2018,11), Artikel-Nummer e002263, 3 Seiten
DOI: 10.1161/CIRCGEN.118.002263
- Wiedmann, Felix Tobias: Atrial fibrillation and heart failure-associated remodeling of two-pore-domain potassium (K2P) channels in murine disease models : focus on TASK-1 / Felix Wiedmann, Jan S. Schulte, Bruna Gomes, Maria-Patapia Zafeiriou, Antonius Ratte, Franziska Rath… , 07 June 2018. - 14 S.
In: Basic research in cardiology, ISSN 1435-1803. 113(2018), 4, Artikel-ID 27, Seite 1-14
DOI: 10.1007/s00395-018-0687-9
- Brandenburg, Sören: Axial tubule junctions activate atrial Ca2+ release across species / Sören Brandenburg, Jan Pawlowitz, Funsho E. Fakuade, Daniel Kownatzki-Danger, Tobias Kohl, Gyuzel Y.… , 08 October 2018. - 21 S.
In: Frontiers in physiology, ISSN 1664-042X. 9(2018) Artikel-Nummer 1227, 21 Seiten
DOI: 10.3389/fphys.2018.01227
- Claßen, Laura: Extracellular vesicles mediate intercellular communication : transfer of functionally active microRNAs by microvesicles into phagocytes / Laura Claßen, Lars-Oliver Tykocinski, Felix Wiedmann, Carolin Birr, Petra Schiller, Christine Tucher… , 30 June 2017. - 15 S.
In: European journal of immunology, ISSN 1521-4141. 47(2017), 9, Seite 1535-1549
DOI: 10.1002/eji.201646595
- Schmidt, Constanze: Stretch-activated two-pore-domain (K2P) potassium channels in the heart : focus on atrial fibrillation and heart failure / Constanze Schmidt, Felix Wiedmann, Stefan M. Kallenberger, Antonius Ratte, Jan S. Schulte, Beatrix S… , 16 May 2017. - 11 S.
In: Progress in biophysics & molecular biology, ISSN 1873-1732. 130(2017), Seite 233-243
DOI: 10.1016/j.pbiomolbio.2017.05.004
- Schmidt, Constanze: Inverse remodelling of K2P3.1 K+ channel expression and action potential duration in left ventricular dysfunction and atrial fibrillation : implications for patient-specific antiarrhythmic drug therapy / Constanze Schmidt, Felix Wiedmann, Xiao-Bo Zhou, Jordi Heijman, Niels Voigt, Antonius Ratte, Siegfri… , 05 January 2017. - 11 S.
In: European heart journal, ISSN 1522-9645. 38(2017), 22, Seite 1764-1774
DOI: 10.1093/eurheartj/ehw559
- Wiedmann, Felix Tobias: Therapeutic targeting of two-pore-domain potassium (K2P) channels in the cardiovascular system / Felix Wiedmann, Constanze Schmidt, Patrick Lugenbiel, Ingo Staudacher, Ann-Kathrin Rahm, Claudia Sey… , 18 March 2016. - 8 S.
In: Clinical science, ISSN 1470-8736. 130(2016), 9, Seite 643-650
DOI: 10.1042/CS20150533
- Hirschberg, Kristóf: Incidental finding of a giant intracardiac angioma infiltrating both ventricles in a 35-year-old woman : a case report / K. Hirschberg, F. Wiedmann, E. Zitron, P. Fortner, J.H. Riffel, E. Chorianopoulos, G. Gdynia, G. Mec… , 12 April 2016. - 5 S.
In: Journal of medical case reports, ISSN 1752-1947. 10(2016) Artikel-Nummer 94, 5 Seiten
DOI: 10.1186/s13256-016-0860-4
- Kallenberger, Stefan M.: A simple, non-invasive score to predict paroxysmal atrial fibrillation / Stefan M. Kallenberger, Christian Schmid, Felix Wiedmann, Derliz Mereles, Hugo A. Katus, Dierk Thoma… , September 28, 2016. - 16 S.
In: PLOS ONE, ISSN 1932-6203. 11(2016,9) Artikel-Nummer e0163621, 16 Seiten
DOI: 10.1371/journal.pone.0163621
- Schmidt, Constanze: Response to letter regarding article, “Upregulation of K2P3.1 K+ current causes action potential shortening in patients with chronic atrial fibrillation” / Constanze Schmidt, MD; Felix Wiedmann, MD; Niels Voigt, MD; Xiao-Bo Zhou, MD; Jordi Heijman, PhD; Si… , 15 Mar 2016. - 2 S.
In: Circulation, ISSN 1524-4539. 133(2016), 11, Seite e440-e441
DOI: 10.1161/CIRCULATIONAHA.115.020662
- Hirschberg, Kristóf: Incidental finding of a giant intracardiac angioma infiltrating both ventricles in a 35-year-old woman: a case report / K. Hirschberg, Felix Wiedmann, E. Zitron, P. Fortner, J.H. Riffel, E. Chorianopoulos, G. Gdynia, G. … . -
London: BioMed Central, 2016. - 1 Online-Ressource (5 Seiten)
- Schmidt, Constanze: Upregulation of K2P3.1 K+ current causes action potential shortening in patients with chronic atrial fibrillation / Constanze Schmidt, Felix Wiedmann, Niels Voigt, Xiao-Bo Zhou, Jordi Heijman, Siegfried Lang, Virgini… , 14 July 2015. - 11 S.
In: Circulation, ISSN 1524-4539. 132(2015), 2, Seite 82-92
DOI: 10.1161/CIRCULATIONAHA.114.012657
- Wiedmann, Felix Tobias: Charakterisierung kardialer Zwei-Porendomänen Kaliumkanäle / vorgelegt von Felix Tobias Wiedmann, 2014 [ersch.] 2015. - VI, 226 Bl. : Ill., graph. Darst.
- Schmidt, Constanze: Inhibition of cardiac two-pore-domain K+ (K-2p) channels : an emerging antiarrhythmic concept / Constanze Schmidt, Felix Wiedmann, Patrick A. Schweizer, Hugo A. Katus, Dierk Thomas. - 6 S.
In: European journal of pharmacology, ISSN 1879-0712. 738(2014), S. 250-255
DOI: 10.1016/j.ejphar.2014.05.056
- Schmidt, Constanze: Cloning, functional characterization, and remodeling of KSUB2P/SUB3.1 (TASK-1) potassium channels in a porcine model of atrial fibrillation and heart failure / Schmidt, C., Wiedmann, F., Langer, C., Tristram, F., Anand, P., Wenzel, W., Lugenbiel, P., Schweizer… , 2014. - 8 S.
In: Heart rhythm, ISSN 1556-3871. 11(2014), 10, Seite 1798-1805
DOI: 10.1016/j.hrthm.2014.06.020
- Rahm, Ann-Kathrin: Functional characterization of zebrafish K2P18.1 (TRESK) two-pore-domain K+ channels / Rahm, Ann-Kathrin; Wiedmann, Felix; Gierten, Jakob; Schmidt, Constanze; Schweizer, Patrick A.; Becke… , 2014. - 10 S.
In: Naunyn-Schmiedeberg's archives of pharmacology, ISSN 1432-1912. 387(2014), 3, Seite 291-300
DOI: 10.1007/s00210-013-0945-1
- Schmidt, Constanze: Cardiac expression and atrial fibrillation-associated remodeling of KSUB2P/SUB2.1 (TREK-1) KSUP+/SUP channels in a porcine model / Schmidt, Constanze ; Wiedmann, Felix ; Tristram, Frank ; Anand, Priya ; Wenzel, Wolfgang ; Lugenbiel… . - 9 S.
In: Life sciences, ISSN 1879-0631. 97(2014), 2, S. 107-115
DOI: 10.1016/j.lfs.2013.12.006
- Li, Jin: Anti-KCNQ1 K+ channel autoantibodies increase IKs current and are associated with QT interval shortening in dilated cardiomyopathy / Jin Li, Claudia Seyler, Felix Wiedmann, Constanze Schmidt, Patrick A. Schweizer, Rüdiger Becker, Hug… , 2013. - 8 S.
In: Cardiovascular research, ISSN 1755-3245. 98(2013), 3 vom: Juni, Seite 496-503
DOI: 10.1093/cvr/cvt046
- Schmidt, Constanze: Class I antiarrhythmic drugs inhibit human cardiac two-pore-domain K+ (K2P) channels / Constanze Schmidt, Felix Wiedmann, Patrick A. Schweizer, Rüdiger Becker, Hugo A. Katus, Dierk Thomas, 23 September 2013. - 12 S.
In: European journal of pharmacology, ISSN 1879-0712. 721(2013), 1/3, Seite 237-248
DOI: 10.1016/j.ejphar.2013.09.029
- Jehle, Julian: Mechanisms of zolpidem-induced long QT syndrome : acute inhibition of recombinant hERG K+ channels and action potential prolongation in human cardiomyocytes derived from induced pluripotent stem cells / J Jehle, E Ficker, X Wan, I Deschenes, J Kisselbach, F Wiedmann, I Staudacher, C Schmidt, PA Schweiz… , 2013. - 15 S.
In: British journal of pharmacology, ISSN 1476-5381. 168(2013), 5 vom: März, Seite 1215-1229
DOI: 10.1111/bph.12002
- Jehle, Julian: Regulation of apoptosis in HL-1 cardiomyocytes by phosphorylation of the receptor tyrosine kinase EphA2 and protection by lithocholic acid / J. Jehle, I. Staudacher, F. Wiedmann, P. A. Schweizer, R. Becker, H. A. Katus, D. Thomas. - 10 S.
In: British journal of pharmacology, ISSN 1476-5381. 167(2012), 7, S. 1563-1572
DOI: 10.1111/j.1476-5381.2012.02117.x
- Schmidt, Constanze: Novel electrophysiological properties of dronedarone : inhibition of human cardiac two-pore-domain potassium (K2P) channels / Constanze Schmidt, Felix Wiedmann, Patrick A. Schweizer, Rüdiger Becker, Hugo A. Katus, Dierk Thomas. - 14 S.
In: Naunyn-Schmiedeberg's archives of pharmacology, ISSN 1432-1912. 385(2012), 10, S. 1003-1016
DOI: 10.1007/s00210-012-0780-9
- Schmidt, Constanze: Kardiale Zwei-Porendomänen-Kaliumkanäle (K2P) : Physiologie, Pharmakologie und therapeutisches Potenzial / C. Schmidt, F. Wiedmann, P.A. Schweizer, H.A. Katus, D. Thomas, 2012. - 5 S.
In: Deutsche medizinische Wochenschrift, ISSN 1439-4413. 137(2012), 33, Seite 1654-1658
DOI: 10.1055/s-0032-1305216
