Offringa, Rienk Prof. Dr. med.Universität HeidelbergHeidelberg
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- Hackert, Thilo (3)
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Publications in heiBIB 
- Mowat, Jeffrey: Discovery of BAY-405 : an azaindole-based MAP4K1 inhibitor for the enhancement of T-Cell immunity against cancer / Jeffrey Mowat, Rafael Carretero, Gabriele Leder, Nuria Aiguabella Font, Roland Neuhaus, Sandra Bernd… , 2024. - 25 S. : Illustrationen, Diagramme
In: Journal of medicinal chemistry, ISSN 1520-4804. 67(2024), 19, Seite 17429-17453
DOI: 10.1021/acs.jmedchem.4c01325
- Salek, Mogjiborahman: optiPRM : a targeted immunopeptidomics LC-MS workflow with ultra-high sensitivity for the detection of mutation-derived tumor neoepitopes from limited input material / Mogjiborahman Salek, Jonas D. Förster, Jonas P. Becker, Marten Meyer, Pornpimol Charoentong, Yanhong… , 5 August 2024. - 16 S.
In: Molecular & cellular proteomics, ISSN 1535-9484. 23(2024), 9, Artikel-ID 100825, Seite 1-16
DOI: 10.1016/j.mcpro.2024.100825
- Tan, Chin Leng: Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy / C.L. Tan, K. Lindner, T. Boschert, Z. Meng, A. Rodriguez Ehrenfried, A. De Roia, G. Haltenhof, A. Fa… , 07 March 2024. - 9 S. : lllustrationen
In: Nature biotechnology, ISSN 1546-1696. (2024), Seite 1-9
DOI: 10.1038/s41587-024-02161-y
- Meng, Zibo: Transcriptome-based identification of tumor-reactive and bystander CD8+ T cell receptor clonotypes in human pancreatic cancer / Zibo Meng, Aaron Rodriguez Ehrenfried, Chin Leng Tan, Laura K. Steffens, Hannes Kehm, Stefan Zens, C… , Nov 2023. - 18 S. : Illustrationen
In: Science translational medicine, ISSN 1946-6242. 15(2023), 722 vom: Nov., Artikel-ID eadh9562, Seite 1-18
DOI: 10.1126/scitranslmed.adh9562
- Kober, Christina: Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964 : a selective small molecule inhibitor for cancer immunotherapy / Christina Kober, Julian Roewe, Norbert Schmees, Lars Roese, Ulrike Roehn, Benjamin Bader, Detlef Sto… , 14 November 2023. - 13 S. : Illustrationen
In: Journal for ImmunoTherapy of Cancer, ISSN 2051-1426. 11(2023), 11, Artikel-ID e007495, Seite 1-13
DOI: 10.1136/jitc-2023-007495
- Sun, Rui: ROTACs leverage signaling-incompetent R-spondin for targeted protein degradation / Rui Sun, Zibo Meng, Hyeyoon Lee, Rienk Offringa, and Christof Niehrs, 20 July 2023. - 23 S.
In: Cell chemical biology, ISSN 2451-9456. 30(2023), 7 vom: Juli, Seite 739-752.e8
DOI: 10.1016/j.chembiol.2023.05.010
- Steinfass, Tamara: Secretogranin II influences the assembly and function of MHC class I in melanoma / Tamara Steinfass, Juliane Poelchen, Qian Sun, Giovanni Mastrogiulio, Daniel Novak, Marlene Vierthale… , 11 March 2023. - 6 S.
In: Experimental hematology & oncology, ISSN 2162-3619. 12(2023), Artikel-ID 29, Seite 1-6
DOI: 10.1186/s40164-023-00387-1
- Sorrentino, Antonio: Salt-inducible kinase 3 protects tumor cells from cytotoxic T-cell attack by promoting TNF-induced NF-κB activation / Antonio Sorrentino, Ayse Nur Menevse, Tillmann Michels, Valentina Volpin, Franziska Christine Durst,… , May 23, 2022. - 18 S.
In: Journal for ImmunoTherapy of Cancer, ISSN 2051-1426. 10(2022), 5, Supplement, Artikel-ID e004258, Seite 1-18
DOI: 10.1136/jitc-2021-004258
- Pinkert, Jessica: T cell-mediated elimination of cancer cells by blocking CEACAM6-CEACAM1 interaction / Jessica Pinkert, Hans-Henning Boehm, Mark Trautwein, Wolf-Dietrich Doecke, Florian Wessel, Yingzi Ge… , 2022
In: OncoImmunology, ISSN 2162-402X. 11(2022), 1, Seite 2008110
DOI: 10.1080/2162402X.2021.2008110
- Baumann, Daniel: p38 MAPK signaling in M1 macrophages results in selective elimination of M2 macrophages by MEK inhibition / Daniel Baumann, Jennifer Drebant, Tanja Hägele, Luisa Burger, Clara Serger, Claudia Lauenstein, Prze… , 20 July 2021. - 9 S.
In: Journal for ImmunoTherapy of Cancer, ISSN 2051-1426. 9(2021), 7, Artikel-ID e002319, Seite 1-9
DOI: 10.1136/jitc-2020-002319
- Gengenbacher, Nicolas: Timed Ang2-targeted therapy identifies the Angiopoietin-tie pathway as key regulator of fatal lymphogenous metastasis / Nicolas Gengenbacher, Mahak Singhal, Carolin Mogler, Ling Hai, Laura Milde, Ashik Ahmed Abdul Pari, … , 2021. - 22 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 2, Seite 424-445
DOI: 10.1158/2159-8290.CD-20-0122
- Baumann, Daniel: Targeting immune-checkpoint inhibitor resistance mechanisms by MEK inhibitor and agonist anti-CD40 antibody combination therapy / Daniel Baumann and Rienk Offringa, October 2020. - 4 S. : Illustrationen
In: Cell stress, ISSN 2523-0204. 4(2020), 10 vom: Okt., Seite 248-251
DOI: 10.15698/cst2020.10.233
- Hartmann, Laura: Photon versus carbon ion irradiation : immunomodulatory effects exerted on murine tumor cell lines / Laura Hartmann, Philipp Schröter, Wolfram Osen, Daniel Baumann, Rienk Offringa, Mahmoud Moustafa, Ra… , 09 December 2020. - 13 S.
In: Scientific reports, ISSN 2045-2322. 10(2020), Artikel-ID 21517, Seite 1-13
DOI: 10.1038/s41598-020-78577-8
- Poschke, Isabel: The outcome of ex vivo TIL expansion is highly influenced by spatial heterogeneity of the tumor T-cell repertoire and differences in intrinsic in vitro growth capacity between T-cell clones / Isabel C. Poschke, Jessica C. Hassel, Aaron Rodriguez-Ehrenfried, Katharina A.M. Lindner, Ignacio He… , April 17, 2020. - 14 S.
In: Clinical cancer research, ISSN 1557-3265. 26(2020), 16, Seite 4289-4301
DOI: 10.1158/1078-0432.CCR-19-3845
- Schröter, Philipp: Radiation-induced alterations in immunogenicity of a murine pancreatic ductal adenocarcinoma cell line / Philipp Schröter, Laura Hartmann, Wolfram Osen, Daniel Baumann, Rienk Offringa, David Eisel, Jürgen … , 20 January 2020. - 10 S.
In: Scientific reports, ISSN 2045-2322. 10(2020) Artikel-Nummer 686, 10 Seiten
DOI: 10.1038/s41598-020-57456-2
- Meng, Zibo: The m6A-related mRNA signature predicts the prognosis of pancreatic cancer patients / Zibo Meng, Qingchen Yuan, Jingyuan Zhao, Bo Wang, Shoukang Li, Rienk Offringa, Xin Jin, and Heshui W… , 29 April 2020. - 11 S.
In: Molecular therapy, ISSN 2372-7705. 17(2020), Seite 460-470
DOI: 10.1016/j.omto.2020.04.011
- Baumann, Daniel: Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy / Daniel Baumann, Tanja Hägele, Julian Mochayedi, Jennifer Drebant, Caroline Vent, Sven Blobner, Julia… , 01 May 2020. - 18 S.
In: Nature Communications, ISSN 2041-1723. 11(2020) Artikel-Nummer 2176, 18 Seiten
DOI: 10.1038/s41467-020-15979-2
- Zurli, Vanessa: Phosphoproteomics of CD2 signaling reveals AMPK-dependent regulation of lytic granule polarization in cytotoxic T cells / Vanessa Zurli, Tommaso Montecchi, Raphael Heilig, Isabel Poschke, Michael Volkmar, Giuliana Wimmer, … , 12 May 2020. - ? S.
In: Science signaling, ISSN 1937-9145. 13(2020,631) Artikel-Nummer eaaz1965, ? Seiten
DOI: 10.1126/scisignal.aaz1965
- Sefrin, Julian Peter: Sensitization of tumors for attack by virus-specific CD8+ T-cells through antibody-mediated delivery of immunogenic T-cell epitopes / Julian P. Sefrin, Lars Hillringhaus, Olaf Mundigl, Karin Mann, Doris Ziegler-Landesberger, Heike Seu… , 21 August 2019. - 14 S.
In: Frontiers in immunology, ISSN 1664-3224. 10(2019, August) Artikel-Nummer 1962, 14 Seiten
DOI: 10.3389/fimmu.2019.01962
- Hackert, Thilo: Vorhabenbezeichnung: Verbundvorhaben: eMED PANC-STRAT: Ein integrativer Ansatz für eine personalisierte Behandlung des Pankreas-Karzinoms - Projekte Universitätsklinik Heidelberg : Abschlussbericht Universität Heidelberg : Berichtszeitraum: 01.11.2016-31.10.2018 / Zuwendungsempfänger: Ruprecht-Karls-Universität Heidelberg ; Autoren: Hackert, Thilo, Prof. Dr.; Str… . -
[Heidelberg]: Ruprecht-Karls-Universität Heidelberg, [2018?]. - 1 Online-Ressource (18 Seiten, 591,90 KB) : Illustrationen
DOI: 10.2314/KXP:1684165687
- Hackert, Thilo: Vorhabenbezeichnung: Verbundvorhaben: eMED PANC-STRAT: Ein integrativer Ansatz für eine personalisierte Behandlung des Pankreas-Karzinoms - Projekte Universitätsklinik Heidelberg : Abschlussbericht Universität Heidelberg : Berichtszeitraum: 01.11.2016-31.10.2018 / Zuwendungsempfänger: Ruprecht-Karls-Universität Heidelberg ; Autoren: Hackert, Thilo, Prof. Dr.; Str… . -
[Heidelberg]: Ruprecht-Karls-Universität Heidelberg, [2018?]. - 17 Blätter, 1 ungezähltes Blatt : Illustrationen
- Grees, Mareike: Optimized dendritic cell vaccination induces potent CD8 T cell responses and anti-tumor effects in transgenic mouse melanoma models / Mareike Grees, Adi Sharbi-Yunger, Christos Evangelou, Daniel Baumann, Gal Cafri, Esther Tzehoval, St… , 26 Mar 2018. - 14 S.
In: OncoImmunology, ISSN 2162-402X. 7(2018), 7, Artikel-ID e1445457, Seite 1-14
DOI: 10.1080/2162402X.2018.1445457
- Cabo, Mariona: Trial Watch : Immunostimulatory monoclonal antibodies for oncological indications / Mariona Cabo, Rienk Offringa, Laurence Zitvogel, Guido Kroemer, Aura Muntasell, Lorenzo Galluzzi
In: OncoImmunology, ISSN 2162-402X. 6(2017,12) Artikel-Nummer e1371896, 16 Seiten
DOI: 10.1080/2162402X.2017.1371896
- Poschke, Isabel: Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma / Isabel Poschke, Marta Faryna, Frank Bergmann, Michael Flossdorf, Claudia Lauenstein, Jennifer Hermes… , 29 Nov 2016. - 12 S.
In: OncoImmunology, ISSN 2162-402X. 5(2016,12), Artikel-Nummer e1240859, 12 Seiten
DOI: 10.1080/2162402X.2016.1240859
- Poschke, Isabel: Next-generation TCR sequencing : a tool to understand T-cell infiltration in human cancers / Isabel Poschke, Michael Flossdorf and Rienk Offringa, 21 October 2016. - 3 S.
In: The journal of pathology: clinical research, ISSN 2056-4538. 240(2016), 4, Seite 384-386
DOI: 10.1002/path.4800
- Khandelwal, Nisit: A high‐throughput RNAi screen for detection of immune‐checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes / Nisit Khandelwal, Marco Breinig, Tobias Speck, Tillmann Michels, Christiane Kreutzer, Antonio Sorren… , 17 February 2015. - 14 S.
In: EMBO molecular medicine, ISSN 1757-4684. 7(2015), 4, Seite 450-463
DOI: 10.15252/emmm.201404414
- Platten, Michael: Cancer immunotherapy : exploiting neoepitopes / Michael Platten, Rienk Offringa. - 2 S.
In: Cell research, ISSN 1748-7838. 25(2015), 8, S. 887-888
DOI: 10.1038/cr.2015.66
- Hartmann, Natalie: Prevailing role of contact guidance in intrastromal T-cell trapping in human pancreatic cancer / Natalie Hartmann, Nathalia A. Giese, Thomas Giese, Isabel Poschke, Rienk Offringa, Jens Werner, and … , April 24, 2014. - 12 S.
In: Clinical cancer research, ISSN 1557-3265. 20(2014), 13, Seite 3422-3433
DOI: 10.1158/1078-0432.CCR-13-2972
