
Ahadova, Aysel Dr. sc. hum.Universität HeidelbergHeidelberg
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Publications in heiBIB 
- Ahadova, Aysel: Reactivation of SOX17 program as immune-evasion mechanism in early colorectal cancer Development / Aysel Ahadova, Matthias Kloor, September 25, 2024. - 3 S.
In: The New England journal of medicine, ISSN 1533-4406. 391(2024), 13, Seite 1250-1252
DOI: 10.1056/NEJMcibr2406393
- Helderman, Noah: Emerge of colorectal cancer in Lynch syndrome despite colonoscopy surveillance : a challenge of hide and seek / Noah C. Helderman, Monique E. van Leerdam, Matthias Kloor, Aysel Ahadova, Maartje Nielsen, 21 March 2024. - 11 S.
In: Critical reviews in oncology, hematology, ISSN 1879-0461. 197(2024), Artikel-ID 104331, Seite 104331-1-104331-11
DOI: 10.1016/j.critrevonc.2024.104331
- Budczies, Jan: Tumour mutational burden : clinical utility, challenges and emerging improvements / Jan Budczies, Daniel Kazdal, Michael Menzel, Susanne Beck, Klaus Kluck, Christian Altbürger, Constan… , October 2024. - 18 S. : Illustrationen
In: Nature reviews, ISSN 1759-4782. 21(2024), 10 vom: Okt., Seite 725-742
DOI: 10.1038/s41571-024-00932-9
- Helderman, Noah: MLH1 Promotor Hypermethylation in Colorectal and Endometrial Carcinomas from Patients with Lynch Syndrome / Noah C. Helderman, Katarina D. Andini, Monique E. van Leerdam, Liselotte P. van Hest, Daniël R. Hoek… , February 2024. - 9 S. : Illustrationen
In: The journal of molecular diagnostics, ISSN 1943-7811. 26(2024), 2 vom: Feb., Seite 106-114
DOI: 10.1016/j.jmoldx.2023.10.005
- Bohaumilitzky, Lena: Liquid biopsy-based early tumor and minimal residual disease detection : new perspectives for cancer predisposition syndromes / Lena Bohaumilitzky, Johannes Gebert, Magnus von Knebel Doeberitz, Matthias Kloor, Aysel Ahadova, 2023-12-05. - 10 S.
In: Medizinische Genetik, ISSN 1863-5490. 35(2023), 4, Seite 259-268
DOI: 10.1515/medgen-2023-2049
- Møller, Pål: Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement / Pal Møller, Toni T. Seppälä, Aysel Ahadova, Emma J. Crosbie, Elke Holinski-Feder, Rodney Scott, Sask… , 11 October 2023. - 12 S. : Diagramme
In: Hereditary cancer in clinical practice, ISSN 1897-4287. 21(2023), Artikel-ID 19, Seite 1-12
DOI: 10.1186/s13053-023-00263-3
- Ahadova, Aysel: A “two-in-one hit” model of shortcut carcinogenesis in MLH1 lynch syndrome carriers / Aysel Ahadova, Albrecht Stenzinger, Toni Seppälä, Robert Hüneburg, Matthias Kloor, Hendrik Bläker, L… , 11 March 2023. - 8 S.
In: Gastroenterology, ISSN 1528-0012. 165(2023), 1, Seite 267-270, e1-e4
DOI: 10.1053/j.gastro.2023.03.007
- Sei, Shizuko: Lynch syndrome cancer vaccines : a roadmap for the development of precision immunoprevention strategies / Shizuko Sei, Aysel Ahadova, Derin B. Keskin, Lena Bohaumilitzky, Johannes Gebert, Magnus von Knebel … , 22 March 2023. - 17 S.
In: Frontiers in oncology, ISSN 2234-943X. 13(2023) vom: März, Artikel-ID 1147590, Seite 1-17
DOI: 10.3389/fonc.2023.1147590
- Witt, Johannes: A simple approach for detecting HLA-A*02 alleles in archival formalin-fixed paraffin-embedded tissue samples and an application example for studying cancer immunoediting / Johannes Witt, Saskia Haupt, Aysel Ahadova, Lena Bohaumilitzky, Vera Fuchs, Alexej Ballhausen, Morit… , January 2023. - 10 S. : Illustrationen
In: HLA, ISSN 2059-2310. 101(2023), 1 vom: Jan., Seite 24-33
DOI: 10.1111/tan.14846
- Andini, Katarina: PMS2-associated Lynch syndrome : past, present and future / Katarina D. Andini, Maartje Nielsen, Manon Suerink, Noah C. Helderman, Jan Jacob Koornstra, Aysel Ah… , 21 February 2023. - 12 S.
In: Frontiers in oncology, ISSN 2234-943X. 13(2023) vom: Feb., Artikel-ID 1127329, Seite 1-12
DOI: 10.3389/fonc.2023.1127329
- Møller, Pål: Colorectal cancer incidences in Lynch syndrome : a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium / Pål Møller, Toni Seppälä, James G. Dowty, Saskia Haupt, Mev Dominguez-Valentin, Lone Sunde, Inge Ber… , 01 October 2022. - 11 S. : Diagramme
In: Hereditary cancer in clinical practice, ISSN 1897-4287. 20(2022), Artikel-ID 36, Seite 1-11
DOI: 10.1186/s13053-022-00241-1
- Bohaumilitzky, Lena: The different immune profiles of normal colonic mucosa in cancer-free Lynch syndrome carriers and Lynch syndrome colorectal cancer patients / Lena Bohaumilitzky, Klaus Kluck, Robert Hüneburg, Richard Gallon, Jacob Nattermann, Martina Kirchner… , 21 February 2022. - 23 S.
In: Gastroenterology, ISSN 1528-0012. 162(2022), 3 vom: März, Seite 907-919.e10
DOI: 10.1053/j.gastro.2021.11.029
- Sina, Mohammad: Identification and management of Lynch syndrome in the Middle East and North African countries : outcome of a survey in 12 countries / Mohammad Sina, Zeinab Ghorbanoghli, Amal Abedrabbo, Fahd Al-Mulla, Rihab Ben Sghaier, Marie-Pierre B… , 2021. - 7 S.
In: Familial cancer, ISSN 1573-7292. 20(2021), 3, Seite 215-221
DOI: 10.1007/s10689-020-00211-3
- Sieber-Frank, Julia: Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells / Julia Sieber-Frank, Hans-Jürgen Stark, Simon Kalteis, Elena-Sophie Prigge, Richard Köhler, Carolin A… , 2021. - 16 S.
In: Cancer medicine, ISSN 2045-7634. 10(2021), 19, Seite 6807-6822
DOI: 10.1002/cam4.4212
- Ten Broeke, Sanne W.: The coding microsatellite mutation profile of PMS2-deficient colorectal cancer / Sanne W. Bajwa-ten Broeke, Alexej Ballhausen, Aysel Ahadova, Manon Suerink, Lena Bohaumilitzky, Flor… , 22 July 2021. - 6 S.
In: Experimental and molecular pathology, ISSN 1096-0945. 122(2021), Artikel-ID 104668, Seite 1-6
DOI: 10.1016/j.yexmp.2021.104668
- Ahadova, Aysel: Distinct mutational profile of lynch dyndrome colorectal cancers diagnosed under regular colonoscopy surveillance / Aysel Ahadova, Pauline Luise Pfuderer, Maarit Ahtiainen, Alexej Ballhausen, Lena Bohaumilitzky, Sven… , 1 June 2021. - 17 S.
In: Journal of Clinical Medicine, ISSN 2077-0383. 10(2021), 11, special issue, Artikel-ID 2458, Seite 1-17
DOI: 10.3390/jcm10112458
- Ahadova, Aysel: The “unnatural” history of colorectal cancer in Lynch syndrome : lessons from colonoscopy surveillance / Aysel Ahadova, Toni T. Seppälä, Christoph Engel, Richard Gallon, John Burn, Elke Holinski-Feder, Ver… , 2021. - 12 S.
In: International journal of cancer, ISSN 1097-0215. 148(2021), 4, Seite 800-811
DOI: 10.1002/ijc.33224
- Michalak, Malwina: Differential glycosite profiling : a versatile method to compare membrane glycoproteomes / Malwina Michalak, Martin Simon Kalteis, Aysel Ahadova, Matthias Kloor, Mark Kriegsmann, Katharina Kr… , 10 June 2021. - 16 S.
In: Molecules, ISSN 1420-3049. 26(2021), 12, Artikel-ID 3564, Seite 1-16
DOI: 10.3390/molecules26123564
- Haupt, Saskia: Mathematical modeling of multiple pathways in colorectal carcinogenesis using dynamical systems with Kronecker structure / Saskia Haupt, Alexander Zeilmann, Aysel Ahadova, Hendrik Bläker, Magnus von Knebel Doeberitz, Matthi… , May 18, 2021. - 31 S.
In: PLoS Computational Biology, ISSN 1553-7358. 17(2021), 5, Artikel-ID e1008970, Seite 1-31
DOI: 10.1371/journal.pcbi.1008970
- Gebert, Johannes: Recurrent frameshift neoantigen vaccine elicits protective immunity with reduced tumor burden and improved overall survival in a Lynch syndrome mouse model / Johannes Gebert, Ozkan Gelincik, Mine Oezcan-Wahlbrink, Jason D. Marshall, Alejandro Hernandez-Sanch… , 2 July 2021. - 28 S.
In: Gastroenterology, ISSN 1528-0012. 161(2021), 4 vom: Okt., Seite 1288-1302.e13
DOI: 10.1053/j.gastro.2021.06.073
- Busch, Elena: Beta-2-microglobulin mutations are linked to a distinct metastatic pattern and a favorable outcome in microsatellite-unstable stage IV gastrointestinal cancers / Elena Busch, Aysel Ahadova, Kosima Kosmalla, Lena Bohaumilitzky, Pauline L. Pfuderer, Alexej Ballhau… , 08 June 2021. - 7 S.
In: Frontiers in oncology, ISSN 2234-943X. 11(2021) vom: 8. Juni, Artikel-ID 669774
DOI: 10.3389/fonc.2021.669774
- Bläker, Hendrik: Age-dependent performance of BRAF mutation testing in Lynch syndrome diagnostics / Hendrik Bläker, Saskia Haupt, Monika Morak, Elke Holinski‐Feder, Alexander Arnold, David Horst, Juli… , 01 September 2020. - 10 S.
In: International journal of cancer, ISSN 1097-0215. 147(2020), 10, Seite 2801-2810
DOI: 10.1002/ijc.33273
- Arnold, Alexander: Correction to: The majority of β-catenin mutations in colorectal cancer is homozygous / Alexander Arnold, Moritz Tronser, Christine Sers, Aysel Ahadova, Volker Endris, Soulafa Mamlouk, Dav… , 26 November 2020. - 1 S.
In: BMC cancer, ISSN 1471-2407. 20(2020), Artikel-ID 1151, Seite 1
DOI: 10.1186/s12885-020-07645-z
- Arnold, Alexander: The majority of β-catenin mutations in colorectal cancer is homozygous / Alexander Arnold, Moritz Tronser, Christine Sers, Aysel Ahadova, Volker Endris, Soulafa Mamlouk, Dav… , 28 October 2020. - 10 S.
In: BMC cancer, ISSN 1471-2407. 20(2020), Artikel-ID 1038, Seite 1-10
DOI: 10.1186/s12885-020-07537-2
- Ballhausen, Alexej: The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution / Alexej Ballhausen, Moritz Jakob Przybilla, Michael Jendrusch, Saskia Haupt, Elisabeth Pfaffendorf, F… , 21 September 2020. - 13 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 11(2020), Artikel-ID 4740, Seite 1-13
DOI: 10.1038/s41467-020-18514-5
- Bohaumilitzky, Lena: Implications of hereditary origin on the immune phenotype of mismatch repair-deficient cancers : systematic literature review / Lena Bohaumilitzky, Magnus von Knebel Doeberitz, Matthias Kloor and Aysel Ahadova, 4 June 2020. - 20 S.
In: Journal of Clinical Medicine, ISSN 2077-0383. 9(2020), 6, Artikel-ID 1741, Seite 1-20
DOI: 10.3390/jcm9061741
- Engel, Christoph: Associations of pathogenic variants in MLH1, MSH2, and MSH6 with risk of colorectal adenomas and tumors and with somatic mutations in patients with Lynch syndrome / Christoph Engel, Aysel Ahadova, Toni T. Seppälä, Stefan Aretz, Marloes Bigirwamungu-Bargeman, Hendri… , 8 January 2020. - 8 S.
In: Gastroenterology, ISSN 1528-0012. 158(2020), 5, Seite 1326-1333
DOI: 10.1053/j.gastro.2019.12.032
- Pfuderer, Pauline Luise: High endothelial venules are associated with microsatellite instability, hereditary background and immune evasion in colorectal cancer / Pauline L. Pfuderer, Alexej Ballhausen, Florian Seidler, Hans-Jürgen Stark, Niels Grabe, Ian M. Fray… , 30 July 2019. - 10 S.
In: British journal of cancer, ISSN 1532-1827. 121(2019), 5, Seite 395-404
DOI: 10.1038/s41416-019-0514-6
- Dominguez-Valentin, Mev: Survival by colon cancer stage and screening interval in Lynch syndrome : a prospective Lynch syndrome database report / Mev Dominguez-Valentin, Toni T. Seppälä, Julian R. Sampson, Finlay Macrae, Ingrid Winship, D. Gareth… , 14 October 2019. - 6 S.
In: Hereditary cancer in clinical practice, ISSN 1897-4287. 17(2019), Artikel-ID 28, Seite 1-6
DOI: 10.1186/s13053-019-0127-3
- Haag, Georg Martin: Prognostic significance of microsatellite-instability in gastric and gastroesophageal junction cancer patients undergoing neoadjuvant chemotherapy / Georg Martin Haag, Elena Czink, Aysel Ahadova, Thomas Schmidt, Leila Sisic, Susanne Blank, Ulrike He… , 2019. - 8 S.
In: International journal of cancer, ISSN 1097-0215. 144(2019), 7, Seite 1697-1703
DOI: 10.1002/ijc.32030
- Seppälä, Toni T.: Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report / Toni T. Seppälä, Aysel Ahadova, Mev Dominguez-Valentin, Finlay Macrae, D. Gareth Evans, Christina Th… . -
London ; Berlin ; Heidelberg: BioMed Central ; Springer, 09 Mai 2019. - 1 Online-Ressource (8 Seiten)
DOI: 10.1186/s13053-019-0106-8
- Seppälä, Toni T.: Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report / Toni T. Seppälä, Aysel Ahadova, Mev Dominguez-Valentin, Finlay Macrae, D. Gareth Evans, Christina Th… , 28 February 2019. - 8 S.
In: Hereditary cancer in clinical practice, ISSN 1897-4287. 17(2019), Artikel-ID 8, Seite 1-8
DOI: 10.1186/s13053-019-0106-8
- Ahadova, Aysel: Three molecular pathways model colorectal carcinogenesis in Lynch syndrome / Aysel Ahadova, Richard Gallon, Johannes Gebert, Alexej Ballhausen, Volker Endris, Martina Kirchner, … , 9 Feb 2018. - 13 S.
In: Molecular cancer research, ISSN 1557-3125. 143(2018), 1, Seite 139-150
DOI: 10.1002/ijc.31300
- Ahadova, Aysel: CTNNB1-mutant colorectal carcinomas with immediate invasive growth : a model of interval cancers in Lynch syndrome / Aysel Ahadova, Magnus von Knebel Doeberitz, Hendrik Bläker, Matthias Kloor. - 8 S.
In: Familial cancer, ISSN 1573-7292. 15(2016), 4, S. 579-586
DOI: 10.1007/s10689-016-9899-z
- Ahadova, Aysel: Dose-dependent effect of 2-deoxy-D-glucose on glycoprotein mannosylation in cancer cells / Aysel Ahadova, Johannes Gebert, Magnus von Knebel Doeberitz, Juergen Kopitz, Matthias Kloor. - 9 S.
In: IUBMB life, ISSN 1521-6551. 67(2015), 3, S. 218-226
DOI: 10.1002/iub.1364
- Jesinghaus, Moritz: Distinctive spatiotemporal stability of somatic mutations in metastasized microsatellite-stable colorectal cancer : $hMoritz Jesinghaus, Thomas Wolf, Nicole Pfarr, Alexander Muckenhuber, Aysel Ahadova, Arne Warth, Benjamin Goeppert, Christine Sers, Matthias Kloor, Volker Endris, Albrecht Stenzinger, Wilko Weichert. - 8 S.
In: The American journal of surgical pathology, ISSN 1532-0979. 39(2015), 8, S. 1140-1147
DOI: 10.1097/PAS.0000000000000423
- Ahadova, Aysel: Mechanisms of action of 2-deoxy-D-glycose in cancer cells and evaluation of novel approaches of application / vorgelegt von Aysel Ahadova, 2015. - XI, 101 Bl. : Ill., graph. Darst.
- Maharramov, Abel M.: Preparation of 2-deoxy-D-glucose coated spio nanoparticles and characterization of their physical, chemical, and biological properties / AM Maharramov, MA Ramazanov, AI Ahadova, M Kloor, Juergen Kopitz, M Von Knebel Doeberitz, AL Shabano… , October-December 2014. - 9 S.
In: Digest journal of nanomaterials & biostructures (DJNB), ISSN 1842-3582. 9(2014), 4, Seite 1461-1469
- Kloor, Matthias: Clinical significance of microsatellite instability in colorectal cancer / Matthias Kloor, Laura Staffa, Aysel Ahadova, Magnus von Knebel Doeberitz. - 9 S.
In: Langenbeck's archives of surgery, ISSN 1435-2451. 399(2014), 1, S. 23-31
DOI: 10.1007/s00423-013-1112-3
- Capper, David: BRAF V600E-specific immunohistochemistry for the exclusion of Lynch syndrome in MSI-H colorectal cancer / David Capper, Anita Voigt, Gergana Bozukova, Aysel Ahadova, Philipp Kickingereder, Andreas von Deiml… , 30 March 2013. - 7 S.
In: International journal of cancer, ISSN 1097-0215. 133(2013), 7, Seite 1624-1630
DOI: 10.1002/ijc.28183
