
Jäger, Natalie Dr. rer. nat.Universität HeidelbergHeidelberg
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Co-Autoren (Uni Heidelberg)
- Lichter, Peter (8)
- Sahm, Felix (7)
- Hutter, Barbara (7)
- Pajtler, Kristian Wilfried (6)
- Sill, Martin (6)
- Korshunov, Andrey (6)
- Jones, Barbara Christine (6)
- Sturm, Dominik (5)
- Pfaff, Elke (5)
- Herold-Mende, Christel (4)
- Kulozik, Andreas (4)
- Tilburg, Cornelis M. van (4)
- Westermann, Frank (4)
- Sharma, Tanvi (4)
- Korbel, Jan Oliver (4)
- Johann, Pascal-David (3)
- Kalle, Christof von (3)
- Witt, Hendrik (3)
- Şeker-Cin, Huriye (3)
- Rausch, Tobias (3)
- Brors, Benedikt (3)
- Kopp-Schneider, Annette (3)
- Schmidt, Manfred (1967-2022) (3)
- Zapatka, Marc (3)
- Remke, Marc (3)
- Kölsche, Christian (2)
- Grund, Kerstin (2)
- Rippe, Karsten (2)
- Pleier, Sabrina Valesca (2)
- Mallm, Jan-Philipp (2)
- Hartmann, Christian (2)
- Unterberg, Andreas (2)
- Bender, Sebastian (2)
- (weitere Einträge vorhanden...)
Co-Autoren (extern)
- Mynarek, Martin (2)
- Kerl, Kornelius (2)
- Alexandrov, Ludmil (2)
- Locatelli, Franco (1)
- Simon, Matthias (1)
- Schwab, Matthias (1)
- Schweinitz, Dietrich von (1)
- Koster, Jan (1)
- Rich, Jeremy (1)
- Schleiermacher, Gudrun (1)
- Aguet, François (1)
- Schneider, Dominik T. (1)
- Schmid, Irene (1)
- Pietschmann, Klaus (1)
- Sommer, Clemens (1)
- Taylor, Michael D. (1)
- Gajjar, Amar (1)
- Mawrin, Christian (1)
- Bailey, Simon (1)
- Tsai, Jessica W. (1)
- Graf, Monika (1)
- Rutkowski, Stefan (1)
- Pugh, Trevor (1)
- Okonechnikov, Konstantin (1)
- Catanzaro, Giuseppina (1)
- Giangaspero, Felice (1)
- Ferretti, Elisabetta (1)
- Vokuhl, Christian (1)
- Wei, Xin (1)
- Bandopadhayay, Pratiti (1)
- Walter, Carolin (1)
- Varlet, Pascale (1)
- Kramm, Christof M. (1)
- (weitere Einträge vorhanden...)
Publikationen in heiBIB 
- Okonechnikov, Konstantin: Oncogene aberrations drive medulloblastoma progression, not initiation / Konstantin Okonechnikov, Piyush Joshi, Verena Körber, Anne Rademacher, Michele Bortolomeazzi, Jan-Ph… , 07 May 2025. - 34 S.
In: Nature, ISSN 1476-4687. (2025), Seite 1-11, [1-13]
DOI: 10.1038/s41586-025-08973-5
- Heipertz, Anna-Elisa: Outcome of children and adolescents with relapsed/refractory/progressive malignancies treated with molecularly informed targeted drugs in the pediatric precision oncology registry INFORM / Anna-Elisa Heipertz, MD, Kristian W. Pajtler, MD, Elke Pfaff, MD, Kathrin Schramm, Dr. rer. nat., Mi… , June 26, 2023. - 12 S. : Illustrationen
In: JCO precision oncology, ISSN 2473-4284. (2023), 7, Artikel-ID e2300015, Seite 1-12
DOI: 10.1200/PO.23.00015
- Okonechnikov, Konstantin: 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma / Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin … , 21 April 2023. - 16 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 2300, Seite 1-16
DOI: 10.1038/s41467-023-38044-0
- Okonechnikov, Konstantin: Mapping pediatric brain tumors to their origins in the developing cerebellum / Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, M… , October 2023. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 10 vom: Okt., Seite 1895-1909
DOI: 10.1093/neuonc/noad124
- Funke, Viktoria: Group-specific cellular metabolism in Medulloblastoma / Viktoria L.E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, … , 05 June 2023. - 16 S. : Illustrationen
In: Journal of translational medicine, ISSN 1479-5876. 21(2023), Artikel-ID 363, Seite 1-16
DOI: 10.1186/s12967-023-04211-6
- Ulrich, Elias: Revana : a comprehensive tool for regulatory variant analysis and visualization of cancer genomes / Elias Ulrich, Stefan M. Pfister and Natalie Jäger, January 2023. - 3 S.
In: Bioinformatics, ISSN 1367-4811. 39(2023), 1, Artikel-ID btac831, Seite 1-3
DOI: 10.1093/bioinformatics/btac831
- Thatikonda, Venu: Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers / Venu Thatikonda, S.M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne N. Gröbner, Gregor W… , 26 January 2023. - 28 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 2 vom: Jan., Seite 276-289
DOI: 10.1038/s43018-022-00509-4
- Sturm, Dominik: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology / Dominik Sturm, David Capper, Felipe Andreiuolo, Marco Gessi, Christian Kölsche, Annekathrin Reinhard… , 16 March 2023. - 10 S.
In: Nature medicine, ISSN 1546-170X. 29(2023), 4, Seite 917-926
DOI: 10.1038/s41591-023-02255-1
- Tsai, Jessica W.: FOXR2 Is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits / Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin … , September 02 2022. - 22 S.
In: Cancer research, ISSN 1538-7445. 82(2022), 17, Seite 2980-3001
DOI: 10.1158/0008-5472.CAN-22-0671
- Catanzaro, Giuseppina: MiR-1248 : a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression / Giuseppina Catanzaro, Zein Mersini Besharat, Andrea Carai, Natalie Jäger, Elena Splendiani, Carole C… , 17 June 2022. - 17 S.
In: Biomarker Research, ISSN 2050-7771. 10(2022), Artikel-ID 44, Seite 1-17
DOI: 10.1186/s40364-022-00389-x
- Keller, Kaylee M.: Target actionability review : a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies / Kaylee M. Keller, Sonja Krausert, Apurva Gopisetty, Dan Luedtke, Jan Koster, Nil A. Schubert, Ana Ro… , 2022. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 162(2022) vom: Feb., Seite 107-117
DOI: 10.1016/j.ejca.2021.11.030
- Beck, Pengbo: The genomic landscape of pediatric renal cell carcinomas / Pengbo Beck, Barbara Selle, Lukas Madenach, David T.W. Jones, Christian Vokuhl, Apurva Gopisetty, Ar… , April 15, 2022. - 24 S.
In: iScience, ISSN 2589-0042. 25(2022), 4 vom: 15. Apr., Artikel-ID 104167, Seite 1-24
DOI: 10.1016/j.isci.2022.104167
- Daub, Joséphine: A systematic analysis of genetic interactions and their underlying biology in childhood cancer / Josephine T. Daub, Saman Amini, Denise J.E. Kersjes, Xiaotu Ma, Natalie Jäger, Jinghui Zhang, Stefan… , 06 October 2021. - 12 S.
In: Communications biology, ISSN 2399-3642. 4(2021), Artikel-ID 1139, Seite 1-12
DOI: 10.1038/s42003-021-02647-4
- Tilburg, Cornelis M. van: The pediatric precision oncology INFORM registry : clinical outcome and benefit for patients with very high-evidence targets / Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler, Karin P. S. Langenberg, Petra Fiesel, Barb… , August 9, 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 11, Seite 2764-2779
DOI: 10.1158/2159-8290.CD-21-0094
- Albert, Thomas: An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma / Thomas K. Albert, Marta Interlandi, Martin Sill, Monika Graf, Natalia Moreno, Kerstin Menck, Astrid … , 2021. - 13 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 4 vom: Apr., Seite 586-598
DOI: 10.1093/neuonc/noaa254
- Ecker, Jonas: Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma / Jonas Ecker, Venu Thatikonda, Gianluca Sigismondo, Florian Selt, Gintvile Valinciute, Ina Oehme, Car… , 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 2 vom: Feb., Seite 226-239
DOI: 10.1093/neuonc/noaa191
- Haag, Daniel: H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model / Daniel Haag, Norman Mack, Patricia Benites Goncalves da Silva, Britta Statz, Jessica Clark, Koji Tan… , 4 February 2021. - 29 S.
In: Cancer cell, ISSN 1878-3686. 39(2021), 3, Seite 407-422.e13
DOI: 10.1016/j.ccell.2021.01.005
- Tilburg, Cornelis M. van: INFORM2 NivEnt : the first trial of the INFORM2 biomarker driven phase I/II trial series : the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies / Cornelis M. van Tilburg, Ruth Witt, Melanie Heiss, Kristian W. Pajtler, Christoph Plass, Isabel Posc… , 05 June 2020. - 12 S.
In: BMC cancer, ISSN 1471-2407. 20(2020) vom: Juni, Artikel-ID 523, Seite 1-12
DOI: 10.1186/s12885-020-07008-8
- Mynarek, Martin: Nonmetastatic medulloblastoma of early childhood : results from the prospective clinical trial HIT-2000 and an extended validation cohort / Martin Mynarek, MD; Katja von Hoff, MD; Torsten Pietsch, MD; Holger Ottensmeier, PhD; Monika Warmuth… , April 24, 2020. - 13 S.
In: Journal of clinical oncology, ISSN 1527-7755. 38(2020), 18, Seite 2028-2040
DOI: 10.1200/JCO.19.03057
- Waszak, Sebastian Martin: Germline elongator mutations in Sonic Hedgehog medulloblastoma / Sebastian M. Waszak, Robinson Giles W, Brian L. Gudenas, Kyle S. Smith, Antoine Forget, Marija Kojic… , 01 April 2020. - 21 S.
In: Nature, ISSN 1476-4687. 580(2020), 7803, Seite 396-401
DOI: 10.1038/s41586-020-2164-5
- Begemann, Matthias: Germline GPR161 mutations predispose to pediatric medulloblastoma / Matthias Begemann, PhD; Sebastian M. Waszak, PhD; Giles W. Robinson, MD; Natalie Jäger, PhD; Tanvi… , October 14, 2019. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 38(2019), 1, Seite 43-50
DOI: 10.1200/JCO.19.00577
- Jones, David T. W.: Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours / David T.W. Jones, Ana Banito, Thomas G.P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Til… , 12 July 2019. - 19 S.
In: Nature reviews, ISSN 1474-1768. 19(2019), 8, Seite 420-438
DOI: 10.1038/s41568-019-0169-x
- Sharma, Tanvi: Second-generation molecular subgrouping of medulloblastoma : an international meta-analysis of Group 3 and Group 4 subtypes / Tanvi Sharma, Edward C. Schwalbe, Daniel Williamson, Martin Sill, Volker Hovestadt, Martin Mynarek, … , 10 May 2019. - 18 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 309-326
DOI: 10.1007/s00401-019-02020-0
- Johann, Pascal-David: RF_Purify : a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression / Pascal David Johann, Natalie Jäger, Stefan M. Pfister and Martin Sill, 16 August 2019. - 9 S.
In: BMC bioinformatics, ISSN 1471-2105. 20(2019) Artikel-Nummer 428, 9 Seiten
DOI: 10.1186/s12859-019-3014-z
- Mack, Stephen C.: Epigenomic alterations define lethal CIMP-positive ependymomas of infancy / S.C. Mack, H. Witt, R.M. Piro, L. Gu, S. Zuyderduyn, A.M. Stütz, X. Wang, M. Gallo, L. Garzia, K. Za… , 19 February 2014. - 9 S.
In: Nature, ISSN 1476-4687. 506(2014), 7489, Seite 445-453
DOI: 10.1038/nature13108
- Jäger, Natalie: Computational analysis of cancer genome sequencing data : the genetic landscape of pediatric brain tumors and X-chromosome hypermutation / [presented by Natalie Jäger], 2014. - XI, 131 S. : Ill., graph. Darst.
- Rieber, Nora: Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies / Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul Northcott, Barbara Hutter, Natalie J… , June 11, 2013. - 11 S.
In: PLOS ONE, ISSN 1932-6203. 8(2013), 6, Artikel-ID e66621, Seite 1-11
DOI: 10.1371/journal.pone.0066621
- Reuss, David: Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations / David E. Reuss, Rosario M. Piro, David T.W. Jones, Matthias Simon, Ralf Ketter, Marcel Kool, Albert … , 12 February 2013. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 351-358
DOI: 10.1007/s00401-013-1093-x
- Weischenfeldt, Joachim: Integrative genomic analyses reveal an androgen-driven somatic alteration landscape in early-onset prostate cancer / Joachim Weischenfeldt, Ronald Simon, Lars Feuerbach, Karin Schlangen, Dieter Weichenhan, Sarah Minne… , February 11, 2013. - 12 S.
In: Cancer cell, ISSN 1878-3686. 23(2013), 2, Seite 159-170
DOI: 10.1016/j.ccr.2013.01.002
- Alexandrov, Ludmil: Corrigendum : Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 9 October 2013. - 1 S.
In: Nature, ISSN 1476-4687. 502(2013), 7470, Seite 258-258
DOI: 10.1038/nature12666
- Alexandrov, Ludmil: Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 14 August 2013. - 7 S.
In: Nature, ISSN 1476-4687. 500(2013), 7463, Seite 415-421
DOI: 10.1038/nature12477
- Jäger, Natalie: Hypermutation of the inactive X chromosome is a frequent event in cancer / Natalie Jäger ... Jan-Philipp Mallm ... Andrey Korshunov... Hendrik Witt ... Karsten Rippe ... Stefa… , 2013. - 15 S.
In: Cell, ISSN 1097-4172. 155(2013), Seite 1-15
DOI: 10.1016/j.cell.2013.09.042
- Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 2012. - 6 S.
In: Nature, ISSN 0028-0836. 488(2012), 7409 vom: 20. Juni, Seite 100-105
- Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 25 July 2012. - 6 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 100-105
DOI: 10.1038/nature11284
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