heiBIB: Mikus, Gerd

Mikus, Gerd apl. Prof. Dr. med.Universität HeidelbergHeidelberg

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englisch (155)
deutsch (8)

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Publikationen in heiBIB

Krohmer, Evelyn: Influence of a short course of ritonavir used as booster in antiviral therapies against SARS-CoV-2 on the exposure of atorvastatin and rosuvastatin / Evelyn Krohmer, Brit Silja Rohr, Felicitas Stoll, Katja S. Gümüs, Mariano Bergamino, Gerd Mikus, Max… , 2025. - 11 S. : Illustrationen
In: Cardiovascular drugs and therapy, ISSN 1573-7241. 39(2025), Seite 325–335
DOI: 10.1007/s10557-023-07538-w
Saleh, Ayatallah: Understanding voriconazole metabolism : a middle-out physiologically-based pharmacokinetic modelling framework integrating in vitro and clinical insights / Ayatallah Saleh, Josefine Schulz, Jan-Frederik Schlender, Linda B.S. Aulin, Amrei-Pauline Konrad, Fr… , 30 October 2024. - 22 S. : Illustrationen
In: Clinical pharmacokinetics, ISSN 1179-1926. 63(2024), 11, Seite 1609-1630
DOI: 10.1007/s40262-024-01434-8
Hohmann, Nicolas: Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin / Nicolas Hohmann, Anna S. Friedrichs, Jürgen Burhenne, Antje Blank, Gerd Mikus, Walter E. Haefeli, August 2024. - 11 S. : Diagramme
In: Clinical and translational science, ISSN 1752-8062. 17(2024), 8 vom: Aug., Artikel-ID e70007, Seite 1-11
DOI: 10.1111/cts.70007
Rohr, Brit Silja: Time course of the interaction between oral short-term ritonavir therapy with three factor Xa inhibitors and the activity of CYP2D6, CYP2C19, and CYP3A4 in healthy volunteers / Brit S. Rohr, Evelyn Krohmer, Kathrin I. Foerster, Jürgen Burhenne, Martin Schulz, Antje Blank, Gerd… , 23 February 2024. - 13 S. : Illustrationen
In: Clinical pharmacokinetics, ISSN 1179-1926. 63(2024), 4, Seite 469-481
DOI: 10.1007/s40262-024-01350-x
Mikus, Gerd: ChatGPT does make up scientific references : should it be currently renamed CheatGPT? : Corresponence / Gerd Mikus, 10 September 2024. - 2 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 80(2024), 12, Seite 1995-1996
DOI: 10.1007/s00228-024-03758-7
McLaughlin, Anna Margarete: Nonlinear mixed-effects model of Z-endoxifen concentrations in Tamoxifen-treated patients from the CEPAM cohort / Anna M. Mc Laughlin, Thomas Helland, Fenja Klima, Stijn L.W. Koolen, Ron H.N. van Schaik, Ron H.J. M… , 2024. - 13 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 113(2024), Seite 1-13
DOI: 10.1002/cpt.3238
Stoll, Felicitas E.: Evaluation of hydroxychloroquine as a perpetrator on cytochrome P450 (CYP) 3A and CYP2D6 activity with microdosed probe drugs in healthy volunteers / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Johanna Weiss, Marleen J. Meyer-Tönnies, Katj… , January 2024. - 9 S. : Illustrationen
In: European journal of drug metabolism and pharmacokinetics, ISSN 2107-0180. 49(2024), 1, Seite 101-109
DOI: 10.1007/s13318-023-00872-2
Allgemeinmedizin : der Mentor für die Facharztprüfung und für die allgemeinmedizinische ambulante Versorgung / herausgegeben von Hans-Dieter Klimm, Frank Peters-Klimm ; begründet von Hans-Ulrich Comberg und Hans… . - 7., überarbeitete und erweiterte Auflage. -
Stuttgart: Thieme, 2023. - 1 Online-Ressource (853 Seiten) : 70 Illustrationen
DOI: 10.1055/b000000120
Leuven, Jason van: Framework for implementing individualised dosing of anti-cancer drugs in routine care : overcoming the logistical challenges / Jason van Leuven, Simon Evans, Ganessan Kichenadasse, Neeltje Steeghs, Billie Bonevski, Gerd Mikus a… , 2023. - 11 S. : Illustrationen
In: Cancers, ISSN 2072-6694. 15(2023), 13, Artikel-ID 3293, Seite 1-11
DOI: 10.3390/cancers15133293
Allgemeinmedizin : der Mentor für die Facharztprüfung und für die allgemeinmedizinische ambulante Versorgung / herausgegeben von Hans-Dieter Klimm, Frank Peters-Klimm ; begründet von Hans-Ulrich Comberg und Hans… . - 7., überarbeitete und erweiterte Auflage. -
Stuttgart ; New York: Georg Thieme Verlag, [2023]. - 853 Seiten : 42 Illustrationen, Diagramme, ISBN 978-3-13-243593-3
Zhu, Vanessa: Evaluation of the drug-drug interaction potential of the novel hepatitis B and D virus entry inhibitor bulevirtide at OATP1B in healthy volunteers / Vanessa Zhu, Jürgen Burhenne, Johanna Weiss, Mathias Haag, Ute Hofmann, Matthias Schwab, Stephan Urb… , 6 April 2023. - 13 S.
In: Frontiers in pharmacology, ISSN 1663-9812. 14(2023) vom: Apr., Artikel-ID 1128547, Seite 1-13
DOI: 10.3389/fphar.2023.1128547
Hermann, Simon: Pharmacokinetics of a microdosed cocktail of three direct oral anticoagulants in children with congenital heart defects : study protocol for a single-centre clinical trial (DOAC-Child) / Simon A. Hermann, Gerd Mikus, Kristine Chobanyan-Jürgens, Matthias Gorenflo, Victoria C. Ziesenitz, January 31, 2023. - 7 S.
In: BMJ paediatrics open, ISSN 2399-9772. 7(2023) vom: Jan., Artikel-ID e001662, Seite 1-7
DOI: 10.1136/bmjpo-2022-001662
Stoll, Felicitas E.: Effect of pantoprazole on the absorption of Hydroxychloroquinea A randomized drug-drug interaction trial in healthy adults / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Kathrin I. Foerster, Simon Hermann, Katja Güm… , 2022. - 6 S.
In: Clinical pharmacology in drug development, ISSN 2160-7648. 11(2022), 2, Seite 285-290
DOI: 10.1002/cpdd.999
Rohr, Brit Silja: Perpetrator characteristics of azole antifungal drugs on three oral factor Xa inhibitors administered as a microdosed cocktail / Brit Silja Rohr, Kathrin Isabelle Foerster, Antje Blank, Jürgen Burhenne, Mazyar Mahmoudi, Walter Em… , 2022. - 13 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 61(2022), 1, Seite 97-109
DOI: 10.1007/s40262-021-01051-9
Mikus, Gerd: Oral drugs against COVID-19 / Gerd Mikus, Kathrin I. Foerster, Theresa Terstegen, Cathrin Vogt, Andre Said, Martin Schulz, Walter … , APR 15 2022. - 10 S. : Illustrationen
In: Deutsches Ärzteblatt international, ISSN 1866-0452. 119(2022), 15, Seite 263-272
DOI: 10.3238/arztebl.m2022.0152
Dyk, Madelé van: Plasma concentration guided dosing of drugs used for the treatment of childhood leukaemias : protocol for a systematic review / Madelé van Dyk, Chelsea Boylan, Robin Michelet, Anna M. Mc Laughlin, Ganessan Kichenadasse, Nikki Ma… , 2022. - 5 S.
In: BMJ open, ISSN 2044-6055. 12(2022), 1, Artikel-ID e053308, Seite 1-5
DOI: 10.1136/bmjopen-2021-053308
Weiß, Johanna: Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound? / Johanna Weiss, Kathrin Isabelle Foerster, Maria Weber, Jürgen Burhenne, Gerd Mikus, Thorsten Lehr, W… , 2022. - 8 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 169(2022), Artikel-ID 106076, Seite 1-8
DOI: 10.1016/j.ejps.2021.106076
Schulz, Josefine: A versatile high-performance LC-MS/MS assay for the quantification of voriconazole and its N-oxide metabolite in small sample volumes of multiple human matrices for biomedical applications / Josefine Schulz, Robin Michelet, Jan F. Joseph, Markus Zeitlinger, Fabian Schumacher, Gerd Mikus, Ch… , 20 February 2022. - 10 S.
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 210(2022), Artikel-ID 114551, Seite 1-10
DOI: 10.1016/j.jpba.2021.114551
Schulz, Josefine: Towards the elucidation of the pharmacokinetics of voriconazole : a quantitative characterization of its metabolism / Josefine Schulz, Antonia Thomas, Ayatallah Saleh, Gerd Mikus, Charlotte Kloft and Robin Michelet, 22 February 2022. - 20 S.
In: Pharmaceutics, ISSN 1999-4923. 14(2022), 3 vom: März, Artikel-ID 477, Seite 1-20
DOI: 10.3390/pharmaceutics14030477
Kluwe, Franziska: Perspectives on model-informed precision dosing in the digital health era : challenges, opportunities, and recommendations / Franziska Kluwe, Robin Michelet, Anna Mueller-Schoell, Corinna Maier, Lena Klopp-Schulze, Madelé van… , 2021. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 109(2021), 1 vom: Jan., Seite 29-36
DOI: 10.1002/cpt.2049
McLaughlin, Anna Margarete: CYP2D6 phenotype explains reported yohimbine concentrations in four severe acute intoxications / Anna Mueller-Schoell, Robin Michelet, Ferdinand Weinelt, Charlotte Kloft, Gerd Mikus, 24 May 2021. - 4 S.
In: Archives of toxicology, ISSN 1432-0738. 95(2021), 8, Seite 2867-2870
DOI: 10.1007/s00204-021-03082-4
Grass, Jana: Absolute bioavailability of microdosed midazolam after buccal administration is dependent on buccal exposure time / Jana Grass, Peter Rose, Jürgen Burhenne, Antje Blank, Walter Emil Haefeli, and Gerd Mikus, 2021. - 8 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 61(2021), 4, Seite 472-479
DOI: 10.1002/jcph.1751
Mahmoudi, Mazyar: Application of microdosed intravenous omeprazole to determine hepatic CYP2C19 activity / Mazyar Mahmoudi, Kathrin I. Foerster, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, and Walter E. Haef… , 2021. - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 61(2021), 6, Seite 789-798
DOI: 10.1002/jcph.1789
Hohmann, Nicolas: Pharmacoenhancement of low crizotinib plasma concentrations in patients with anaplastic lymphoma kinase-positive non-small cell lung cancer using the CYP3A inhibitor cobicistat / Nicolas Hohmann, Farastuk Bozorgmehr, Petros Christopoulos, Gerd Mikus, Antje Blank, Jürgen Burhenne… , 2021. - 5 S.
In: Clinical and translational science, ISSN 1752-8062. 14(2021), 2, Seite 487-491
DOI: 10.1111/cts.12921
McLaughlin, Anna Margarete: Computational treatment simulations to assess the need for personalized tamoxifen dosing in breast cancer patients of different biogeographical groups / Anna Mueller-Schoell, Robin Michelet, Lena Klopp-Schulze, Madelé van Dyk, Thomas E. Mürdter, Matthia… , 18 May 2021. - 13 S.
In: Cancers, ISSN 2072-6694. 13(2021), 10, Artikel-ID 2432, Seite 1-13
DOI: 10.3390/cancers13102432
Mikus, Gerd: Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs / Gerd Mikus, Kathrin I. Foerster, Marlene Schaumaeker, Marie-Louise Lehmann, Jürgen Burhenne, Walter … , 2020. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 86(2020), 8, Seite 1632-1641
DOI: 10.1111/bcp.14277
Wiebe, Sabrina: Composite midazolam and 1′-OH midazolam population pharmacokinetic model for constitutive, inhibited and induced CYP3A activity / Sabrina T. Wiebe, Andreas D. Meid, Gerd Mikus, 08 August 2020. - 16 S.
In: Journal of pharmacokinetics and pharmacodynamics, ISSN 1573-8744. 47(2020), 6, Seite 527-542
DOI: 10.1007/s10928-020-09704-1
Rohr, Brit Silja: Proposal of a safe and effective study design for CYP3A-mediated drug-drug interactions / Brit Silja Rohr and Gerd Mikus, 2020. - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 60(2020), 10, Seite 1294-1303
DOI: 10.1002/jcph.1622
Vay, Manuela: Oral yohimbine as a new probe drug to predict CYP2D6 activity : results of a fixed-sequence phase I trial / Manuela Vay, Marleen Julia Meyer, Antje Blank, Gisela Skopp, Peter Rose, Mladen Vassilev Tzvetkov, G… , 15 February 2020. - 13 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 59(2020), 7, Seite 927-939
DOI: 10.1007/s40262-020-00862-6
Wiebe, Sabrina: Midazolam microdosing applied in early clinical development for drug-drug interaction assessment / Sabrina T. Wiebe, Andreas Huennemeyer, Werner Kadus, Markus Goettel, Alen Jambrecina, Armin Schultz,… , 2021. - 11 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 87(2021), 1, Seite 178-188
DOI: 10.1111/bcp.14389
Sauter, Max: New insights into the pharmacokinetics of vancomycin after oral and intravenous administration : an investigation in beagle dogs / Max Sauter, Philipp Uhl, Andreas D. Meid, Gerd Mikus, Jürgen Burhenne, Walter E. Haefeli, 20 March 2020. - 5 S.
In: Journal of pharmaceutical sciences, ISSN 1520-6017. 109(2020), 6, Seite 2090-2094
DOI: 10.1016/j.xphs.2020.03.012
Foerster, Kathrin: Drug-Drug interactions with direct oral anticoagulants / Kathrin I. Foerster, Simon Hermann, Gerd Mikus, Walter E. Haefeli, 11 March 2020. - 14 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 59(2020), 8, Seite 967-980
DOI: 10.1007/s40262-020-00879-x
Jedamzik, Julia: No alteration of Cyp3A4 activity after major hepatectomy in the early postoperative period : a prospective before-after study / J. Jedamzik, J. Mühlbacher, F. Fitschek, C. Schwarz, J. Burhenne, U. Asenbaum, K. Kaczirek, G. Mikus, 12 May 2020. - 5 S.
In: International journal of surgery, ISSN 1743-9159. 79(2020), Seite 131-135
DOI: 10.1016/j.ijsu.2020.05.010
Stoll, Felicitas E.: Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19) : A structured summary of a study protocol for a randomised controlled trial / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Kathrin I. Foerster, Simon Hermann, Katja Häu… , 29 June 2020. - 2 S.
In: Trials, ISSN 1468-6694. 21(2020), Artikel-ID 584, Seite 1-2
DOI: 10.1186/s13063-020-04476-y
Blank, Antje: Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial / Antje Blank, Kristin Fürle, Anja Jäschke, Gerd Mikus, Monika Lehmann, Johannes Hüsing, Kirsten Heiss… , 31 January 2020. - 15 S.
In: npj vaccines, ISSN 2059-0105. 5(2020), Artikel-ID 10, Seite 1-15
DOI: 10.1038/s41541-020-0160-2
Li, Xia: A physiologically based pharmacokinetic model of voriconazole integrating time-dependent inhibition of CYP3A4, genetic polymorphisms of CYP2C19 and predictions of drug-drug interactions / Xia Li, Sebastian Frechen, Daniel Moj, Thorsten Lehr, Max Taubert, Chih-hsuan Hsin, Gerd Mikus, Pert… , 2020. - 28 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 59(2020), 6, Seite 781-808
DOI: 10.1007/s40262-019-00856-z
Vay, Manuela: Quantification of microdosed oral yohimbine and its major metabolite in human plasma in the picogram range / Manuela Vay, Max Sauter, Gerd Mikus & Jürgen Burhenne. - Zweitveröffentlichung. -
London: Future Science, 2019. - 1 Online-Ressource (12 Seiten)
DOI: 10.11588/heidok.00028431
Gade, Christina: Midazolam pharmacokinetics in obese and non-obese children and adolescents / Christina Gade, Eva Sverrisdóttir, Kim Dalhoff, Jesper Sonne, Mia Østergaard Johansen, Hanne Rolighe… , 2020. - 12 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 59(2020), 5, Seite 643-654
DOI: 10.1007/s40262-019-00838-1
Vaughns, Janelle D.: Prophylactic use of enoxaparin in adolescents during bariatric surgery : a prospective clinical study / Janelle D. Vaughns, Victoria C. Ziesenitz, Elaine F. Williams, Evan P. Nadler, Gerd Mikus, Johannes … , 2020. - 6 S.
In: Obesity surgery, ISSN 1708-0428. 30(2020), 1, Seite 63-68
DOI: 10.1007/s11695-019-04135-5
Ziesenitz, Victoria C.: Methodological considerations on CYP2D6 phenoconversion due to drug-drug interaction / Victoria C. Ziesenitz and Gerd Mikus, 10 February 2019. - 1 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 105(2019), 5, Seite 1076
DOI: 10.1002/cpt.1336
Mikus, Gerd: Microdosed cocktail of three oral factor Xa inhibitors to evaluate drug-drug interactions with potential perpetrator drugs / Gerd Mikus, Kathrin I. Foerster, Marlene Schaumaeker, Marie-Louise Lehmann, Jürgen Burhenne, Walter … , 4 March 2019. - 9 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 58(2019), 9, Seite 1155-1163
DOI: 10.1007/s40262-019-00749-1
Vay, Manuela: Simultaneous quantification of the CYP2D6 substrate yohimbine, its metabolite 11-OH-yohimbine, and the CYP2D6 inhibitor paroxetine in human plasma / Manuela Vay, Gisela Skopp, Gerd Mikus and Jürgen Burhenne, 4 November 2019. - 8 S.
In: Analytical methods, ISSN 1759-9679. 11(2019), 47, Seite 5976-5983
DOI: 10.1039/C9AY01715A
Geist, Marcus Julian Peter: Minor contribution of cytochrome P450 3A activity on fentanyl exposure in palliative care cancer patients / Marcus J.P. Geist, Victoria C. Ziesenitz, Hubert J. Bardenheuer, Juergen Burhenne, Gisela Skopp & Ge… , 10 October 2019. - 6 S.
In: Scientific reports, ISSN 2045-2322. 9(2019) Artikel-Nummer 14635, 6 Seiten
DOI: 10.1038/s41598-019-51279-6
Geist, Marcus Julian Peter: Decreased Cytochrome P450 3A activity in palliative patients with haematological diseases : Potential impact on supportive drug therapies / Marcus J.P. Geist, Nelly Siller, Gerlinde Egerer, Hubert Bardenheuer, Juergen Burhenne, Gerd Mikus, 27 March 2019. - 6 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 125(2019), 2, Seite 117-122
DOI: 10.1111/bcpt.13232
Mikus, Gerd: Probes and cocktails for drug-drug interaction evaluation : the future is microdosing? / Gerd Mikus, 12 February 2019. - 3 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 105(2019), 6, Seite 1335-1337
DOI: 10.1002/cpt.1350
Geist, Marcus Julian Peter: Alteration of drug-metabolizing enzyme activity in palliative care patients : microdosed assessment of cytochrome P450 3A / Marcus Geist, Hubert Bardenheuer, Juergen Burhenne and Gerd Mikus, April 26, 2019. - 6 S.
In: Palliative medicine, ISSN 1477-030X. 33(2019), 7, Seite 850-855
DOI: 10.1177/0269216319843629
Hohmann, Nicolas: A follow-up report on potential drug interactions with clementines : two single case experiments show no effect on CYP3A-dependent midazolam clearance / Nicolas Hohmann, Gerd Mikus, Walter Emil Haefeli, Vedat Schwenger, Giuseppe Gattuso, Davide Barreca,… , 15 May 2019. - 5 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 133(2019), Seite 54-58
DOI: 10.1016/j.ejps.2019.03.013
Greenblatt, David J.: Ketoconazole and liver injury : a five-year update / David J. Greenblatt and Gerd Mikus, 01 January 2019. - 3 S.
In: Clinical pharmacology in drug development, ISSN 2160-7648. 8(2019), 1, Seite 6-8
DOI: 10.1002/cpdd.652
Kiene, Klara: Microdosed midazolam for the determination of cytochrome P450 3A activity : Development and clinical evaluation of a buccal film / Klara Kiene, Noriyuki Hayasi, Jürgen Burhenne, Ryo Uchitomi, Claudia Sünderhauf, Yasmin Schmid, Manu… , 16 May 2019. - 6 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 135(2019), Seite 77-82
DOI: 10.1016/j.ejps.2019.05.010
Vay, Manuela: Isotopically labelled paroxetine standard allows for definite structure elucidation of the paroxetine tandem mass spectrum / Manuela Vay, Marius Majewsky, Gerd Mikus, 2018 Aug 15. - 2 S.
In: Rapid communications in mass spectrometry, ISSN 1097-0231. 32(2018), 15, Seite 1311-1312
DOI: 10.1002/rcm.8178
Huppertz, Andrea: Rivaroxaban and macitentan can be coadministered without dose adjustment but the combination of rivaroxaban and St John's wort should be avoided / Andrea Huppertz, Lars Werntz, Andreas D. Meid, Kathrin I. Foerster, Jürgen Burhenne, David Czock, Ge… , 07 September 2018. - 11 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 84(2018), 12, Seite 2903-2913
DOI: 10.1111/bcp.13757
Geist, Marcus Julian Peter: In vivo CYP3A activity in palliative care patients : study protocol for a single arm prospective trial / Marcus J.P. Geist, Hubert J. Bardenheuer, Jürgen Burhenne, and Gerd Mikus, 1 May 2018. - 3 S.
In: Journal of palliative medicine, ISSN 1557-7740. 21(2018), 5, Seite 686-688
DOI: 10.1089/jpm.2017.0461
Gade, Christina: Higher chlorzoxazone clearance in obese children compared with nonobese peers / C. Gade, K. Dalhoff, T.S. Petersen, T. Riis, C. Schmeltz, E. Chabanova, H.R. Christensen, G. Mikus, … , 04 April 2018. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 84(2018), 8, Seite 1738-1747
DOI: 10.1111/bcp.13602
Geist, Marcus Julian Peter: Impact of patient education on plasma concentrations and effectiveness of posaconazole oral suspension under clinical conditions / Marcus J.P. Geist, Gerlinde Egerer, Gerd Mikus, Antje Blank, Nicolas Hohmann, Werner J. Heinz, Alexa… , 2019. - 6 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 124(2019), 1, Seite 56-61
DOI: 10.1111/bcpt.13093
Theile, Dirk: Methadone against cancer : Lost in translation / Dirk Theile and Gerd Mikus, 08 March 2018. - 9 S.
In: International journal of Cancer Studies & Research, ISSN 2167-9118. 143(2018), 8, Seite 1840-1848
DOI: 10.1002/ijc.31356
Gade, Christina: Obesity-induced CYP2E1 activity in children / Christina Gade, Kim Dalhoff, Tonny Petersen, Troels Riis, Camilla Schmeltz, Elizaveta Chabanova, Han… , 2019. - 2 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 85(2019), 2, Seite 458-459
DOI: 10.1111/bcp.13813
Vay, Manuela: No alteration of voriconazole concentration by plasmapheresis in a critically ill patient : letter to the editor / Manuela Vay, Kathrin I. Foerster, Mazyar Mahmoudi, Jessica Seeßle, Gerd Mikus, 2019. - 2 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 75(2019), 2, Seite 287-288
DOI: 10.1007/s00228-018-2582-6
Blank, Antje: The NTCP-inhibitor Myrcludex B : effects on bile acid disposition and tenofovir pharmacokinetics / A Blank, A Eidam, M Haag, N Hohmann, J Burhenne, M Schwab, SFJ van de Graaf, MR Meyer, HH Maurer, K … , 2018. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 103(2018), 2, Seite 341-348
DOI: 10.1002/cpt.744
Ziesenitz, Victoria C.: Pharmacokinetics of fentanyl and its derivatives in children : a comprehensive review / Victoria C. Ziesenitz, Janelle D. Vaughns, Gilbert Koch, Gerd Mikus, Johannes N. van den Anker, 2018. - 25 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 57(2018), 2, Seite 125-149
DOI: 10.1007/s40262-017-0569-6
Wolfert, Christina Lisa: Management von chronischem Schmerz mit retardiertem Tilidin : Lebensqualität und Bedeutung der Komedikation für den Tilidinmetabolismus / C. Wolfert, M. Merbach, G. Stammler, O. Emrich, A.M. Meid, J. Burhenne, A. Blank, G. Mikus, 8. Juni 2017. - 8 S.
In: Der Schmerz, ISSN 1432-2129. 31(2017), 5, Seite 516-523
DOI: 10.1007/s00482-017-0228-8
Mikus, Gerd: Semisimultaneous midazolam administration to evaluate the time course of CYP3A activation by a single oral dose of efavirenz / Gerd Mikus, Tilman Heinrich, Julia Bödigheimer, Claudia Röder, Anne-Kathrin Matthee, Johanna Weiss, … , July 2017. - 7 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 57(2017), 7, Seite 899-905
DOI: 10.1002/jcph.879
Mikus, Gerd: Role of CYP3A4 in kinase inhibitor metabolism and assessment of CYP3A4 activity / Gerd Mikus, Kathrin Isabelle Foerster, December 2017. - 8 S.
In: Translational cancer research, ISSN 2219-6803. 6(2017), S10, Seite S1592-S1599
DOI: 10.21037/tcr.2017.09.10
Vaughns, Janelle D.: Use of fentanyl in adolescents with clinically severe obesity undergoing bariatric surgery : a pilot study / Janelle D. Vaughns, Victoria C. Ziesenitz, Elaine F. Williams, Alvina Mushtaq, Ricarda Bachmann, Gis… , 25 February 2017. - 7 S.
In: Pediatric drugs, ISSN 1179-2019. 19(2017), 3, Seite 251-257
DOI: 10.1007/s40272-017-0216-6
Meid, Andreas: Combinations of QTc-prolonging drugs : towards disentangling pharmacokinetic and pharmacodynamic effects in their potentially additive nature / Andreas D. Meid, Irene Bighelli, Sarah Mächler, Gerd Mikus, Giuseppe Carrà, Mariasole Castellazzi, C… , August 28, 2017. - 14 S.
In: Therapeutic advances in psychopharmacology, ISSN 2045-1261. 7(2017), 12, Seite 251-264
DOI: 10.1177/2045125317721662
Meid, Andreas: Real-world complexity of atrial fibrillation treatment with oral anticoagulants : design and interpretation of pharmacoepidemiological studies / Andreas D. Meid, Sarah Mächler, Walter E. Haefeli, Gerd Mikus, 21 July 2017. - 4 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 83(2017), 10, Seite 2321-2324
DOI: 10.1111/bcp.13348
Hossain, Md. Amin: Inhibition of human cytochromes P450 in vitro by ritonavir and cobicistat / Md Amin Hossain, Timothy Tran, Tianmeng Chen, Gerd Mikus and David J. Greenblatt. - 8 S.
In: Journal of pharmacy and pharmacology, ISSN 2042-7158. 69(2017), 12, S. 1786-1793
DOI: 10.1111/jphp.12820
Hohmann, Nicolas: Autoinhibitory properties of the parent but not of the N-oxide metabolite contribute to infusion rate-dependent voriconazole pharmacokinetics / Nicolas Hohmann, Rebecca Kreuter, Antje Blank, Johanna Weiss, Jürgen Burhenne, Walter E. Haefeli and… . - 12 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 83(2017), 9, S. 1954-1965
DOI: 10.1111/bcp.13297
Burhenne, Jürgen: Intracellular vorinostat accumulation and its relationship to histone deacetylase activity in soft tissue sarcoma patients / Jürgen Burhenne, Lu Liu, Christoph E. Heilig, Andreas D. Meid, Margarete Leisen, Thomas Schmitt, Ber… , 13 June 2017. - 7 S.
In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 80(2017), 2, Seite 433-439
DOI: 10.1007/s00280-017-3357-y
Högl, Birgit: Acute and painful exacerbation of RLS and PLM induced by opioid interaction - withdrawal syndrome / Birgit Högl, Hanns Lohner, Gerd Mikus, Helmut Huff, 27 May 2017. - 2 S.
In: Sleep medicine, ISSN 1878-5506. 36(2017), Seite 186-187
DOI: 10.1016/j.sleep.2017.05.010
Breithaupt-Grögler, Kerstin: Who is a ‘healthy subject’? : consensus results on pivotal eligibility criteria for clinical trials / Kerstin Breithaupt-Groegler, Christoph Coch, Martin Coenen, Frank Donath, Katharina Erb-Zohar, Klaus… . - 8 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 73(2017), 4, S. 409-416
DOI: 10.1007/s00228-016-2189-8
Suzuki, Yosuke: Ultra-sensitive and selective quantification of endothelin-1 in human plasma using ultra-performance liquid chromatography coupled to tandem mass spectrometry / Yosuke Suzuki, Lukas Witt, Walter Mier, Gerd Mikus, Christoph Markert, Walter E. Haefeli, Jürgen Bur… . - 7 S.
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 142(2017), S. 84-90
DOI: 10.1016/j.jpba.2017.04.038
Algeelani, Sara: In vitro inhibition of human UGT isoforms by ritonavir and cobicistat / Sara Algeelani, Novera Alam, Md Amin Hossain, Gerd Mikus & David J. Greenblatt. - 6 S.
In: Xenobiotica, ISSN 1366-5928. (2017), S. 1-6
DOI: 10.1080/00498254.2017.1370655
Theile, Dirk: Clementine juice has the potential for drug interactions : in vitro comparison with grapefruit and mandarin juice / Dirk Theile, Nicolas Hohmann, Dominik Kiemel, Giuseppe Gattuso, Davide Barreca, Gerd Mikus, Walter E… , Januar 15, 2017. - 10 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 97(2017), Seite 247-256
DOI: 10.1016/j.ejps.2016.11.021
O'Brien, Tony: European Pain Federation position paper on appropriate opioid use in chronic pain management / T. O'Brien, L.L. Christrup, A.M. Drewes, M.T. Fallon, H.G. Kress, H.J. McQuay, G. Mikus, B.J. Morlio… . - 17 S.
In: European journal of pain, ISSN 1532-2149. 21(2017), 1, S. 3-19
DOI: 10.1002/ejp.970
Hohmann, Nicolas: CYP3A activity : towards dose adaptation to the individual / Nicolas Hohmann, Walter E. Haefeli, & Gerd Mikus, 26 March 2016. - 19 S.
In: Expert opinion on drug metabolism & toxicology, ISSN 1744-7607. 12(2016), 5, Seite 479-497
DOI: 10.1517/17425255.2016.1163337
Hohmann, Nicolas: Treatment with rilpivirine does not alter plasma concentrations of the CYP3A substrates tadalafil and midazolam in humans / Nicolas Hohmann, Raphael Reinhard, Sven Schnaidt, Lukas Witt, Alexandra Carls, Jürgen Burhenne, Gerd… , May 1, 2016. - 7 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 71(2016), 8, Seite 2241-2247
DOI: 10.1093/jac/dkw125
Hohmann, Nicolas: Dose-dependent bioavailability and CYP3A inhibition contribute to non-linear pharmacokinetics of voriconazole / Nicolas Hohmann, Franziska Kocheise, Alexandra Carls, Jürgen Burhenne, Johanna Weiss, Walter E. Haef… . - 11 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 55(2016), 12, S. 1535-1545
DOI: 10.1007/s40262-016-0416-1
Witt, Lukas: Ultrasensitive quantification of the CYP2E1 probe chlorzoxazone and its main metabolite 6-hydroxychlorzoxazone in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry after chlorzoxazone microdosing / Lukas Witt, Yosuke Suzuki, Nicolas Hohmann, Gerd Mikus, Walter E. Haefeli, Jürgen Burhenne. - 7 S.
In: Journal of chromatography, ISSN 1873-376X. 1027(2016), S. 207-213
DOI: 10.1016/j.jchromb.2016.05.049
Schmitt, Thomas: Vorinostat in refractory soft tissue sarcomas : results of a multi-centre phase II trial of the German Soft Tissue Sarcoma and Bone Tumour Working Group (AIO) / Thomas Schmitt, Regine Mayer-Steinacker, Frank Mayer, Viktor Grünwald, Jochen Schütte, Jörg T. Hartm… , September 2016. - 9 S.
In: European journal of cancer, ISSN 1879-0852. 64(2016), Seite 74-82
DOI: 10.1016/j.ejca.2016.05.018
Outeiro, Noémi: No increased risk of ketoconazole toxicity in drug-drug interaction studies / Noémi Outeiro, MDent, Nicolas Hohmann, MD, and Gerd Mikus, MD,MSc. - 9 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 56(2016), 10, S. 1203-1211
DOI: 10.1002/jcph.795
Blank, Antje: First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B / Antje Blank, Christoph Markert, Nicolas Hohmann, Alexandra Carls, Gerd Mikus, Thorsten Lehr, Alexand… . - 7 S.
In: Journal of hepatology, ISSN 1600-0641. 65(2016), 3, S. 483-489
DOI: 10.1016/j.jhep.2016.04.013
Hohmann, Nicolas: St. John’s wort treatment in women bears risks beyond pharmacokinetic drug interactions / Nicolas Hohmann, Anna Maus, Alexandra Carls, Walter E. Haefeli, Gerd Mikus, 2016. - 3 S.
In: Archives of toxicology, ISSN 1432-0738. 90(2016), 4, Seite 1013-1015
DOI: 10.1007/s00204-015-1532-7
Schmitz-Winnenthal, Friedrich Hubertus: Anti-angiogenic activity of VXM01, an oral T-cell vaccine against VEGF receptor 2, in patients with advanced pancreatic cancer : a randomized, placebo-controlled, phase 1 trial / Friedrich H. Schmitz-Winnenthal, Nicolas Hohmann, Andreas G. Niethammer, Tobias Friedrich, Heinz Lub… , 16 Mar 2015. - 13 S.
In: OncoImmunology, ISSN 2162-402X. 4(2015,4) Artikel-Nummer e1001217, 13 Seiten
DOI: 10.1080/2162402X.2014.1001217
Markert, Christoph: The effect of induction of CYP3A4 by St John's Wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype / Christoph Markert, Ida Maria Kastner, Regina Hellwig, Peter Kalafut, Yvonne Schweizer, Michael Marcu… , 2015. - 6 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 116(2015), 5, Seite 423-428
DOI: 10.1111/bcpt.12332
Ziesenitz, Victoria C.: Pharmacokinetic interaction of intravenous fentanyl with ketoconazole / Victoria C. Ziesenitz, MD, Sonja K. König, MD, Nina S. Mahlke, MD, Gisela Skopp, PhD, Walter E. Haef… . - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 55(2015), 6, S. 708-717
DOI: 10.1002/jcph.469
Hohmann, Nicolas: Use of microdose phenotyping to individualise dosing of patients / Nicolas Hohmann, Walter E. Haefeli, Gerd Mikus. - 8 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 54(2015), 9, S. 893-900
DOI: 10.1007/s40262-015-0278-y
Mikus, Gerd: Urine drug testing for oxycodone and its metabolites as a tool for drug-drug interactions? / Gerd Mikus. - 2 S.
In: Journal of analytical toxicology, ISSN 1945-2403. 39(2015), 1, S. 81-82
DOI: 10.1093/jat/bku111
Siller, Nelly: Normal CYP3A activity during arsenic trioxide therapy / Nelly Siller, Gerlinde Egerer, Tilman Bochtler, Nicolas Hohmann, Gerd Mikus, 16 April 2014. - 2 S.
In: Annals of hematology, ISSN 1432-0584. 93(2014), 11, Seite 1941-1942
DOI: 10.1007/s00277-014-2076-2
Markert, Christoph: Influence of St. John’s wort on the steadystate pharmacokinetics and metabolism of bosentan / Christoph Markert, Prisca Ngui, Regina Hellwig, Theresia Wirsching, Ida Maria Kastner, Klaus-Dieter … , 2014. - 9 S.
In: International journal of clinical pharmacology and therapeutics. 52(2014), 04, Seite 328-336
DOI: 10.5414/CP202048
Hohmann, Nicolas: Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans / Nicolas Hohmann, Franziska Kocheise, Alexandra Carls, Jürgen Burhenne, Walter E. Haefeli, Gerd Mikus, 2015. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 79(2015), 2, Seite 278-285
DOI: 10.1111/bcp.12502
Markert, Christoph: Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults / Christoph Markert, Theresia Wirsching, Regina Hellwig, Jürgen Burhenne, Johanna Weiss, Klaus-Dieter … , 2014. - 8 S.
In: International journal of clinical pharmacology and therapeutics. 52(2014), 11, Seite 957-964
DOI: 10.5414/CP202164
Mahlke, Nina Sophia: Quantitative low-volume assay for simultaneous determination of fentanyl, norfentanyl, and minor metabolites in human plasma and urine by liquid chromatography—tandem mass spectrometry (LC-MS/MS) / Nina Sophia Mahlke · Victoria Ziesenitz · Gerd Mikus · Gisela Skopp, 6 July 2014. - 8 S.
In: International journal of legal medicine, ISSN 1437-1596. 128(2014), 5, Seite 771-778
DOI: 10.1007/s00414-014-1040-y
Eichbaum, Christine: Pre-systemic elimination of tilidine : localization and consequences for the formation of the active metabolite nortilidine / Christine Eichbaum, Kristin Mathes, Jürgen Burhenne, Christoph Markert, Antje Blank and Gerd Mikus, 2015. - 5 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 116(2015), 2, Seite 129-133
DOI: 10.1111/bcpt.12328
Hohmann, Nicolas: Response to "Can CYP3A activity be evaluated for drug interaction using a nanogram dose of probe drug?" : Evaluation of CYP3A activity with microdoses of midazolam / N Hohmann, B Halama, N Siller, G Mikus, WE Haefeli. - 2 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 95(2014), 5, S. 490-491
DOI: 10.1038/clpt.2014.28
Hohmann, Nicolas: Effects and risks associated with novel psychoactive substances : mislabeling and sale as bath salts, spice, and research chemicals / Nicolas Hohmann, Gerd Mikus, David Czock. - 12 S.
In: Deutsches Ärzteblatt international, ISSN 1866-0452. 111(2014), 9, S. 139-147
DOI: 10.3238/arztebl.2014.0139
Schmitt, Thomas: Aprepitant, Granisetron, and Dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose Melphalan in autologous transplantation for multiple myeloma : results of a randomized, placebo-controlled phase III trial / Thomas Schmitt, Hartmut Goldschmidt, Kai Neben, Anja Freiberger, Johannes Hüsing, Martina Gronkowski… , October 20 2014. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 32(2014), 30, Seite 3413-3420
DOI: 10.1200/JCO.2013.55.0095
Dolton, Michael J.: Understanding variability with voriconazole using a population pharmacokinetic approach : implications for optimal dosing / Michael J. Dolton, Gerd Mikus, Johanna Weiss, John E. Ray and Andrew J. McLachlan. - 9 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 69(2014), 6, S. 1633-1641
DOI: 10.1093/jac/dku031
Carls, Alexandra: Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity / Alexandra Carls, Julia Jedamzik, Lukas Witt, Nicolas Hohmann, Juergen Burhenne, Gerd Mikus. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 78(2014), 6, S. 1433-1440
DOI: 10.1111/bcp.12497
Klimas, Romina: Morphine-6-glucuronide is responsible for the analgesic effect after morphine administration : a quantitative review of morphine, morphine-6-glucuronide, and morphine-3-glucuronide / R. Klimas, G. Mikus. - 10 S.
In: British journal of anaesthesia, ISSN 1471-6771. 113(2014), 6, S. 935-944
DOI: 10.1093/bja/aeu186
Theile, Dirk: Deceptive argumentation against diagnostic microdosing of anticancer drugs / Dirk Theile andGerd Mikus. - 2 S.
In: International journal of cancer, ISSN 1097-0215. 135(2014), 7, S. 1753-1754
DOI: 10.1002/ijc.28806
Markert, Christoph: CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers / C. Markert, J. Burhenne, J. Weiss, G. Mikus and W. E. Haefeli. - 2 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 95(2014), 3, S. 250-251
DOI: 10.1038/clpt.2013.188
Markert, Christoph: Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers / Christoph Markert, Yvonne Schweizer, Regina Hellwig, Theresia Wirsching, Klaus-Dieter Riedel, Juerge… , 2014. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 77(2014), 1, Seite 141-148
DOI: 10.1111/bcp.12177
Seidling, Hanna: What, if all alerts were specific : estimating the potential impact on drug interaction alert burden / Hanna M. Seidling ; Ulrike Klein ; Matthias Schaier ; David Czock ; Dirk Theile ; Markus G. Pruszydl… . - 7 S.
In: International journal of medical informatics, ISSN 1872-8243. 83(2014), 4, S. 285-291
DOI: 10.1016/j.ijmedinf.2013.12.006
Siller, Nelly: Prolonged sedation of lorazepam due to absent UGT2B4/2B7 glucuronidation / Nelly Siller ; Gerlinde Egerer ; Johanna Weiss ; Gerd Mikus. - 2 S.
In: Archives of toxicology, ISSN 1432-0738. 88(2014), 1, S. 179-180
DOI: 10.1007/s00204-013-1173-7
Stoll, Felicitas E.: Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity / Felicitas Stoll, Jürgen Burhenne, Berthold Lausecker, Johanna Weiss, Torben Thomsen, Walter Emil Hae… , 2013. - 6 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 53(2013), 11, Seite 1199-1204
DOI: 10.1002/jcph.161
Skopp, Gisela: An in vitro experiment on the interaction of charcoal or wheat bran with 11-nor-9-carboxy-Δ9-tetrahydrocannabinol and its glucuronide / Gisela Skopp, Gerd Mikus, 2013. - 5 S.
In: Analytical and bioanalytical chemistry, ISSN 1618-2650. 405(2013), 29, Seite 9449-9453
DOI: 10.1007/s00216-013-7381-4
Ziesenitz, Victoria C.: Fentanyl pharmacokinetics is not dependent on hepatic uptake by organic anion-transporting polypeptide 1B1 in human beings / Victoria C. Ziesenitz, Sonja K. König, Nina Mahlke, Ricarda Jantos, Gisela Skopp, Johanna Weiss, Wal… , 08 March 2013. - 6 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 113(2013), 1, Seite 43-48
DOI: 10.1111/bcpt.12066
Ziesenitz, Victoria C.: Cytochrome P450-3A phenotyping using Midazolam is not altered by OATP1B1 polymorphisms / V.C. Ziesenitz, J. Weiss, W.E. Haefeli, and G. Mikus, 28 February 2013. - 1 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 93(2013), 5, Seite 388
DOI: 10.1038/clpt.2013.46
Hof, Herbert: Candida-Infektionen im hohen Alter / H. Hof, G. Mikus, 2013. - 7 S.
In: Zeitschrift für Gerontologie und Geriatrie, ISSN 1435-1269. 46(2013), 1, Seite 64-70
DOI: 10.1007/s00391-011-0280-4
Markert, Christoph: Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1 / Christoph Markert, Regina Hellwig, Jürgen Burhenne, Michael Marcus Hoffmann, Johanna Weiss, Gerd Mik… , 9 June 2013. - 9 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 10, Seite 1785-1793
DOI: 10.1007/s00228-013-1529-1
Klimas, Romina: Contribution of oxycodone and its metabolites to the overall analgesic effect after oxycodone administration / Romina Klimas, Diana Witticke, Sarah El Fallah & Gerd Mikus, 14 Mar 2013. - 12 S.
In: Expert opinion on drug metabolism & toxicology, ISSN 1744-7607. 9(2013), 5, Seite 517-528
DOI: 10.1517/17425255.2013.779669
Halama, Birte: A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions / B Halama, N Hohmann, J Burhenne, J Weiss, G Mikus and WE Haefeli, 20 March 2013. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 93(2013), 6, Seite 564-571
DOI: 10.1038/clpt.2013.27
Geist, Marcus Julian Peter: Steady-state pharmacokinetics and metabolism of voriconazole in patients / Marcus J.P. Geist, Gerlinde Egerer, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss and Gerd Mik… , 13 June 2013. - 8 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 68(2013), 11, Seite 2592-2599
DOI: 10.1093/jac/dkt229
Eichbaum, Christine: Concentration effect relationship of CYP3A inhibition by ritonavir in humans / Christine Eichbaum, Marianna Cortese, Antje Blank, Jürgen Burhenne, Gerd Mikus, 9 June 2013. - 6 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 10, Seite 1795-1800
DOI: 10.1007/s00228-013-1530-8
Wustrow, Isabel Katharina Ruth: In vitro identification of the cytochrome P450 isozymes involved in the N-demethylation of the active opioid metabolite nortilidine to bisnortilidine / Isabel Wustrow, Klaus-Dieter Riedel, Gerd Mikus, Johanna Weiss, 15 February 2012. - 7 S.
In: Naunyn-Schmiedeberg's archives of pharmacology, ISSN 1432-1912. 385(2012), 6, Seite 633-639
DOI: 10.1007/s00210-012-0737-z
Niethammer, Andreas Gerhard: Double-blind, placebo-controlled first in human study to investigate an oral vaccine aimed to elicit an immune reaction against the VEGF-Receptor 2 in patients with stage IV and locally advanced pancreatic cancer / Andreas G. Niethammer, Heinz Lubenau, Gerd Mikus, Philipp Knebel, Nicolas Hohmann, Christine Leoward… , 20 August 2012. - 8 S.
In: BMC cancer, ISSN 1471-2407. 12(2012) Artikel-Nummer 361, 8 Seiten
DOI: 10.1186/1471-2407-12-361
Keubler, Anja: Drug interaction of efavirenz and midazolam : efavirenz activates the CYP3A-mediated midazolam 1′-Hydroxylation in vitro / Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus, Jürgen Burhenne, May 16, 2012. - 5 S.
In: Drug metabolism and disposition, ISSN 1521-009X. 40(2012), 6, Seite 1178-1182
DOI: 10.1124/dmd.111.043844
Grün, Barbara: Contribution of CYP2C19 and CYP3A4 to the formation of the active nortilidine from the prodrug tilidine / Barbara Grün, Ulrike Merkel, Klaus‐Dieter Riedel, Johanna Weiss & Gerd Mikus, 2 March 2012. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 74(2012), 5, Seite 854-863
DOI: 10.1111/j.1365-2125.2012.04261.x
Burhenne, Jürgen: Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1′-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry / Jürgen Burhenne, Birte Halama, Monika Maurer, Klaus-Dieter Riedel, Nicolas Hohmann, Gerd Mikus, Walt… , 15 January 2012. - 12 S.
In: Analytical and bioanalytical chemistry, ISSN 1618-2650. 402(2012), 7, Seite 2439-2450
DOI: 10.1007/s00216-011-5675-y
Fuchs, Ines Verena: Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity / Ines Fuchs, Verena Hafner-Blumenstiel, Christoph Markert, Jürgen Burhenne, Johanna Weiss, Walter Emi… . - 7 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 3, S. 507-513
DOI: 10.1007/s00228-012-1388-1
Burhenne, Jürgen: Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry / Jürgen Burhenne; Birte Halama; Monika Maurer; Klaus-Dieter Riedel; Nicolas Hohmann; Gerd Mikus; Wal… , 2012. - 12 S.
In: Analytical & bioanalytical chemistry, ISSN 1618-2642. 402(2012), 7, Seite 2439-2450
Hassan, Arwa: Modulators of very low voriconazole concentrations in routine therapeutic drug monitoring / Arwa Hassan, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss, Gerd Mikus, Walter E. Haefeli, Dav… , [February 2011]. - 8 S.
In: Therapeutic drug monitoring, ISSN 1536-3694. 33(2011), 1, Seite 86-93
DOI: 10.1097/FTD.0b013e31820530cd
Katzenmaier, Stephanie Katharina: Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using a limited sampling strategy / S Katzenmaier, C Markert, K-D Riedel, J Burhenne, WE Haefeli and G Mikus, 21 September 2011. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 90(2011), 5, Seite 666-673
DOI: 10.1038/clpt.2011.164
Rudofsky, Leonie: Daily honey consumption does not change CYP3A activity in humans / Leonie Fetzner, Jürgen Burhenne, PhD, Johanna Weiss, PhD, Michael Völker, Matthias Unger, PhD, Gerd … , 2011. - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 51(2011), 8, Seite 1223-1232
DOI: 10.1177/0091270010382022
Aklillu, Eleni: Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method / Eleni Aklillu, Sabina Mugusi, Eliford Ngaimisi, Michael Marcus Hoffmann, Sonja König, Victoria Ziese… , 01 June 2011. - 7 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 67(2011), 11, Artikel-ID 1139, Seite 1-7
DOI: 10.1007/s00228-011-1065-9
Sommerer, Claudia: Pharmacokinetic and pharmacodynamic analysis of enteric-coated mycophenolate sodium : limited sampling strategies and clinical outcome in renal transplant patients / Claudia Sommerer, Sandra Müller-Krebs, Matthias Schaier, Petra Glander, Klemens Budde, Vedat Schweng… , 11 March 2010. - 12 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 69(2010), 4, Seite 346-357
DOI: 10.1111/j.1365-2125.2009.03612.x
Hafner-Blumenstiel, Verena: Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration / Verena Hafner, David Czock, Jürgen Burhenne, Klaus-Dieter Riedel, Jürgen Bommer, Gerd Mikus, Christo… , 1 June 2010. - 7 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 54(2010), 6, Seite 2596-2602
DOI: 10.1128/aac.01540-09
Hafner-Blumenstiel, Verena: Effect of simultaneous induction and inhibition of CYP3A by St John's wort and ritonavir on CYP3A activity / V Hafner, M Jäger, A-K Matthée, R Ding, J Burhenne, WE Haefeli and G Mikus, 2010. - 6 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 87(2010), 2, Seite 191-196
DOI: 10.1038/clpt.2009.206
Hafner-Blumenstiel, Verena: Arzneimittelinteraktionen / V. Hafner, B. Grün, C. Markert, D. Czock, G. Mikus, W.E. Haefeli, 4. Februar 2010. - 12 S.
In: Der Internist, ISSN 1432-1289. 51(2010), 3, Seite 359-370
DOI: 10.1007/s00108-009-2553-1
Clemens, Katri Elina: Combined oral prolonged-release oxycodone and naloxone in opioid-induced bowel dysfunction : review of efficacy and safety data in the treatment of patients experiencing chronic pain / Katri Elina Clemens, Gerd Mikus, 2010. - 14 S.
In: Expert opinion on pharmacotherapy, ISSN 1744-7666. 11(2010), 2 vom: Feb., Seite 297-310
DOI: 10.1517/14656560903483222
Burhenne, Jürgen: No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment / Jürgen Burhenne, Anne-Kathrin Matthée, Ivana Pasáková, Claudia Röder, Tilman Heinrich, Walter Emil H… , 1 October 2010. - 7 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 54(2010), 10, Seite 4185-4191
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Katzenmaier, Stephanie Katharina: Proposal of a new limited sampling strategy to predict CYP3A activity using a partial AUC of midazolam / Stephanie Katzenmaier, Christoph Markert, Gerd Mikus, 3 August 2010. - 5 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 66(2010), 11, Seite 1137-1141
DOI: 10.1007/s00228-010-0878-2
Egerer, Gerlinde: The NK1 receptor antagonist aprepitant does not alter the pharmacokinetics of high-dose melphalan chemotherapy in patients with multiple myeloma / Gerlinde Egerer, Kathrin Eisenlohr, Martina Gronkowski, Juergen Burhenne, Klaus-Dieter Riedel & Gerd… , 30 August 2010. - 5 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 70(2010), 6 vom: Dez., Seite 903-907
DOI: 10.1111/j.1365-2125.2010.03792.x
Bountogo, Mamadou: Efficacy of methylene blue monotherapy in semi-immune adults with uncomplicated falciparum malaria : a controlled trial in Burkina Faso / Mamadou Bountogo, Augustin Zoungrana, Boubacar Coulibaly, Christina Klose, Ulrich Mansmann, Frank P.… , 10 May 2010. - 5 S.
In: Tropical medicine & international health, ISSN 1365-3156. 15(2010), 6, Seite 713-717
DOI: 10.1111/j.1365-3156.2010.02526.x
Dietz, Lisa: The urinary disposition of intravenously administered 11-nor-9-carboxy-delta-9-tetrahydrocannabinol in humans / Lisa Dietz, Anna Glaz-Sandberg, Hang Nguyen, Gisela Skopp, Gerd Mikus, Rolf Aderjan, 2007. - 5 S.
In: Therapeutic drug monitoring, ISSN 1536-3694. 29(2007), 3 vom: Juni, Seite 368-372
DOI: 10.1097/FTD.0b013e31805ba6fd
Derendorf, Hartmut: Ciclesonid : pharmakokinetische und pharmakodynamische Eigenschaften / Hartmut Derendorf, Melanie Hübner, Bernd Drewelow, Uwe Fuhr, Christoph H. Gleiter, Björn Lemmer, Ger… , 2007. - 6 S.
In: Arzneimitteltherapie, ISSN 0723-6913. 25(2007), 3, Seite 89-94
Oberwittler, Heike: Significant pharmacokinetic and pharmacodynamic interaction of warfarin with the NO-independent sGC activator HMR1766 / Heike Oberwittler, Andreas Hirschfeld‐Warneken, Roland Wesch, Hans Willerich, Lenore Teichert, Karl-… , 2007. - 8 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 47(2007), 1, Seite 70-77
DOI: 10.1177/0091270006294540
Kees, Frieder: Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers / Kees, Frieder ; Bucher, Michael ; Schweda, Frank ; Gschaidmeier, Harald ; Burhenne, Juergen ; Mikus,… , 2006. - 9 S.
In: Therapeutic drug monitoring, ISSN 1536-3694. 28(2006), 3, Seite 312-320
DOI: 10.1097/01.ftd.0000211804.89440.74
Busse, Dagmar: Cardiovascular effects of (R)- and (S)-verapamil and racemic verapamil in humans : a placebo-controlled study / Dagmar Busse, Silke Templin, Gerd Mikus, Matthias Schwab, Ute Hofmann, Michel Eichelbaum, Kari T. Ki… , 4 July 2006. - 7 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 62(2006), 8, Seite 613-619
DOI: 10.1007/s00228-006-0154-7
Geist, Marcus Julian Peter: Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype / Marcus J.P. Geist, Gerlinde Egerer, Jürgen Burhenne, Gerd Mikus, 2006. - 2 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 50(2006), 9, Seite 3227-3228
DOI: 10.1128/AAC.00551-06
Hesse, Christiane: Kinetics and dynamics of the peripheral neurokinin-1 receptor antagonist SLV317 in healthy individuals / Christiane Hesse, Steffen P. Luntz, Heike Siedler, Kristina Unnebrink, Gerd Mikus, Marianne de Bruij… , 24 January 2006. - 6 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 61(2006), 4, Seite 414-419
DOI: 10.1111/j.1365-2125.2006.02590.x
Bergner, Raoul: Fluconazole dosing in continuous veno-venous haemofiltration (CVVHF) : need for a high daily dose of 800 mg / Raoul Bergner, Martin Hoffmann, Klaus-Dieter Riedel, Gerd Mikus, Dirk M. Henrich, Walter E. Haefeli,… , 2006. - 5 S.
In: Nephrology, dialysis, transplantation, ISSN 1460-2385. 21(2006), 4, Seite 1019-1023
DOI: 10.1093/ndt/gfi284
Rengelshausen, Jens: Pharmacokinetics of a netilmicin loading dose on the first postnatal day in preterm neonates with very w gestational age / Jens Rengelshausen, Bernd Beedgen, Konstantina Tsamouranis, Gerd Mikus, Ingeborg Walter-Sack, Walter… , 25 July 2006. - 5 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 62(2006), 9, Seite 773-777
DOI: 10.1007/s00228-006-0153-8
Mikus, Gerd: Potent cytochrome P450 2C19 genotype-related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir / Gerd Mikus, Verena Schöwel, Magdalena Drzewinska, Jens Rengelshausen, Reinhard Ding, Klaus-Dieter Ri… , 19 August 2006. - 10 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 80(2006), 2, Seite 126-135
DOI: 10.1016/j.clpt.2006.04.004
Ehrhardt, Manuela: Monitoring of lopinavir and ritonavir in peripheral blood mononuclear cells, plasma, and ultrafiltrate using a selective and highly sensitive LC/MS/MS assay / Manuela Ehrhardt, Marion Möck, Walter E. Haefeli, Gerd Mikus, Jürgen Burhenne, 2007. - 10 S.
In: Journal of chromatography, ISSN 1873-376X. 850(2007), 1, Seite 249-258
DOI: 10.1016/j.jchromb.2006.11.037
Meissner, Peter: Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841] / Peter E. Meissner, Germain Mandi, Steffen Witte, Boubacar Coulibaly, Ulrich Mansmann, Jens Rengelsha… , 22 September 2005. - 9 S.
In: Malaria journal, ISSN 1475-2875. 4(2005), Artikel-ID 45
DOI: 10.1186/1475-2875-4-45
Mikus, Gerd: Influence of CYP2D6 genetics on opioid kinetics, metabolism and response / Gerd Mikus and Johanna Weiss, 1. März 2005. - 10 S.
In: Current pharmacogenomics, ISSN 1875-6204. 3(2005), 1, Seite 43-52
DOI: 10.2174/1570160053175018
Rengelshausen, Jens: Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics / Jens Rengelshausen, Maria Banfield, Klaus-Dieter Riedel, Jürgen Burhenne, Johanna Weiss, Torben Thom… , 25 July 2005. - 9 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 78(2005), 1, Seite 25-33
DOI: 10.1016/j.clpt.2005.01.024
Streit, Michael: Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m) / Michael Streit, Christoph Göggelmann, Christoph Dehnert, Jürgen Burhenne, Klaus-Dieter Riedel, Elmar… , 04 February 2005. - 8 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 61(2005), 1, Seite 39-46
DOI: 10.1007/s00228-004-0886-1
Bobbert, Monika: Integrierte Psychosomatik : Implementierung und Evaluation eines Unterrichtsmoduls für StudentInnen der Inneren Medizin / Monika Bobbert, Christoph Nikendei, Stephan Zipfel, Bernd Kraus, Hans-Christoph Friederich, Rainer F… , 2005. - 6 S.
In: GMS-Zeitschrift für medizinische Ausbildung, ISSN 1860-7446. 22(2005), 4, Seite 1-6
Ding, Reinhard: Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers / Reinhard Ding, Yorki Tayrouz, Klaus-Dieter Riedel, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, and W… , 01 July 2004. - 12 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 76(2004), 1, Seite 73-84
DOI: 10.1016/j.clpt.2004.02.008
Fröhlich, Margit: Association of the CYP3A5 A6986G (CYP3A5*3) polymorphism with saquinavir pharmacokinetics / Margit Fröhlich, Michael M Hoffmann, Jürgen Burhenne, Gerd Mikus, Johanna Weiss & Walter E Haefeli, 21 June 2004. - 2 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 58(2004), 4, Seite 443-444
DOI: 10.1111/j.1365-2125.2004.02159.x
Mikus, Gerd: Reduction of saquinavir exposure by coadministration of loperamide / Gerd Mikus, Laila Schmidt, Jürgen Burhenne, Reinhard Ding, Klaus-Dieter Riedel, Yorki Tayrouz, Johan… , 2004. - 10 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 43(2004), 14, Seite 1015-1024
DOI: 10.2165/00003088-200443140-00004
Riedel, Klaus-Dieter: Simultaneous determination of hypericin and hyperforin in human plasma with liquid chromatography-tandem mass spectrometry / Klaus-Dieter Riedel, Karin Rieger, Meret Martin-Facklam, Gerd Mikus, Walter E.Haefeli, Jürgen Burhen… , 5 November 2004. - 7 S.
In: Journal of chromatography, ISSN 1873-376X. 813(2004), 1-2, Seite 27-33
DOI: 10.1016/j.jchromb.2004.09.061
Rengelshausen, Jens: Pharmacokinetic interaction of chloroquine and methylene blue combination against malaria / Jens Rengelshausen, Jürgen Burhenne, Margit Fröhlich, Yorki Tayrouz, Shio Kumar Singh, Klaus-Dieter … , 13 October 2004. - 7 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 60(2004), 10, Seite 709-715
DOI: 10.1007/s00228-004-0818-0
Rengelshausen, Jens: Contribution of increased oral bioavailability and reduced nonglomerular renal clearance of digoxin to the digoxin-clarithromycin interaction / Jens Rengelshausen, Christoph Göggelmann, Jürgen Burhenne, Klaus-Dieter Riedel, Jochen Ludwig, Johan… , 2003. - 7 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 56(2003), 1 vom: Juli, Seite 32-38
DOI: 10.1046/j.1365-2125.2003.01824.x
Ketabi-Kiyanvash, Nahal: P-glycoprotein modulation by the designer drugs methylenedioxymethamphetamine, methylenedioxyethylamphetamine and paramethoxyamphetamine / Nahal Ketabi-Kiyanvash, Johanna Weiss, Walter Emil Haefeli & Gerd Mikus, 2003. - 6 S.
In: Addiction biology, ISSN 1369-1600. 8(2003), 4, Seite 413-418
DOI: 10.1080/13556210310001646475
Burhenne, Jürgen: Highly sensitive determination of saquinavir in biological samples using liquid chromatography-tandem mass spectrometry / Jürgen Burhenne, Klaus-Dieter Riedel, Meret Martin-Facklam, Gerd Mikus, Walter E. Haefeli, 2003. - 10 S.
In: Journal of chromatography, ISSN 1873-376X. 784(2003), 2, Seite 233-242
DOI: 10.1016/S1570-0232(02)00803-6
Tayrouz Haffar, Yorki Antoine: Pharmacokinetic and pharmaceutic interaction between digoxin and Cremophor RH40 / Yorki Tayrouz, Reinhard Ding, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss, Torsten Hoppe-Tic… , 17 May 2003. - 9 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 73(2003), 5, Seite 397-405
DOI: 10.1016/S0009-9236(03)00059-6
Mikus, Gerd: Polymorpher Metabolismus von Opioiden : Grundlagen und Klinische Konsequenzen / vorgelegt von Gerd Mikus, 2003. - Getr. Zählung : Ill., graph. Darst.
Tayrouz Haffar, Yorki Antoine: Ritonavir increases loperamide plasma concentrations without evidence for P-glycoprotein involvement / Yorki Tayrouz, Beate Ganssmann, Reinhard Ding, Andrea Klingmann, Rolf Aderjan, Jürgen Burhenne, Walt… , 05 November 2001. - 10 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 70(2001), 5, Seite 405-414
DOI: 10.1016/S0009-9236(01)35864-2
Mikus, Gerd: Die Anwendung eines mit stabilen Isotopen markierten Arzneimittels zur simultanen Bestimmung der relativen biologischen Verfügbarkeit einer Verapamil Retard / vorgelegt von Gerd Mikus, 1985. - 42 S. : graph. Darst.

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