
Grünewald, Thomas G. P. Habil.; Dr. phil.; Dr. med.Universität HeidelbergHeidelberg
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Co-Autoren (Uni Heidelberg)
- Kölsche, Christian (3)
- Kulozik, Andreas (3)
- Deimling, Andreas von (3)
- Jones, David T. W. (3)
- Westermann, Frank (3)
- Banito, Ana (3)
- Carreño-Gonzalez, Martha J. (3)
- Sill, Martin (2)
- Schirmacher, Peter (2)
- Mechtersheimer, Gunhild (2)
- Sturm, Dominik (2)
- Kriegsmann, Mark (2)
- Milde, Till (2)
- Korshunov, Andrey (2)
- Kool, Marcel (2)
- Schrimpf, Daniel (2)
- Stichel, Damian (2)
- Herrmann, Carl (2)
- Sharma, Ashwini Kumar (2)
- Kommoss, Felix (2)
- Quintero, Andrés (2)
- Imle, Roland (2)
- Fröhling, Stefan (2)
- Henrich, Kai-Oliver (2)
- Pajtler, Kristian Wilfried (1)
- Harnoß, Julian-Camill (1)
- Johann, Pascal-David (1)
- Sinn, Peter (1)
- Debus, Jürgen (1)
- Hell, Rüdiger (1)
- Hohenberger, Peter (1)
- Poschet, Gernot (1)
- Kommoss, Friedrich (1)
- (weitere Einträge vorhanden...)
Co-Autoren (extern)
- Picard, Daniel (3)
- Kirchner, Thomas (3)
- Orth, Martin Franz (3)
- Grossetête, Sandrine (3)
- Delattre, Olivier (3)
- Keller, Charles (2)
- Bestvater, Felix (2)
- Bendrin, Katja (2)
- Elkabets, Moshe (2)
- Kahlert, Ulf D. (2)
- Lambrechts, Diether (2)
- Fendt, Sarah-Maria (2)
- Moretti, Matteo (2)
- Metzler, Markus (2)
- Stühler, Kai (2)
- Strauch, Konstantin (2)
- Van Elsen, Joke (2)
- Vandekeere, Anke (2)
- Xue, Busheng (2)
- Prexler, Carolin (2)
- Burdach, Stefan E. G. (2)
- Reichert, Andreas (2)
- Wehweck, Fabienne S. (2)
- Amatruda, James F. (2)
- Toretsky, Jeffrey A. (2)
- Kovar, Heinrich (2)
- Planque, Mélanie (2)
- Alonso, Javier (2)
- Rotblat, Barak (2)
- Hruby, Laura (2)
- Grohar, Patrick J. (2)
- Watson, Sarah (2)
- Koster, Jan (1)
- (weitere Einträge vorhanden...)
Publikationen in heiBIB 
- Gegner, Hagen M.: A single-sample workflow for joint metabolomic and proteomic analysis of clinical specimens / Hagen M. Gegner, Thomas Naake, Karim Aljakouch, Aurelien Dugourd, Georg Kliewer, Torsten Müller, Dus… , 05 July 2024. - 17 S. : Illustrationen
In: Clinical proteomics, ISSN 1559-0275. 21(2024), Artikel-ID 49, Seite 1-17
DOI: 10.1186/s12014-024-09501-9
- Levy, Tal: mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism / Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn Snaebjörnsson, Ran Marciano… , 14 May 2024. - 20 S. : Diagramme
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 4083, Seite 1-20
DOI: 10.1038/s41467-024-48386-y
- Levy, Tal: mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism / Tal Levy, Kai Voeltzke, Laura Hruby, Khawla Alasad, Zuelal Bas, Marteinn Snaebjörnsson, Ran Marciano… , 14 May 2024. - 20 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 4083, Seite 1-20
DOI: 10.1038/s41467-024-48386-y
- Jin, Darui: Teacher-student collaborated multiple instance learning for pan-cancer PDL1 expression prediction from histopathology slides / Darui Jin, Shangying Liang, Artem Shmatko, Alexander Arnold, David Horst, Thomas G. P. Grünewald, Mo… , 09 April 2024. - 14 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 15(2024), 1, Artikel-ID 3063, Seite 1-14
DOI: 10.1038/s41467-024-46764-0
- Ohmura, Shunya: Optimizing ATR inhibition and Cisplatin Synergy in Ewing Sarcoma / Shunya Ohmura and Thomas G.P. Grünewald, 15 August 2024. - 3 S.
In: Clinical cancer research, ISSN 1557-3265. 30(2024), 16 vom: Aug., Seite 3358-3360
DOI: 10.1158/1078-0432.CCR-24-1047
- Wachtel, Marco: Functional classification of fusion proteins in sarcoma / Marco Wachtel, Didier Surdez, Thomas G.P. Grünewald and Beat W. Schäfer, 29 March 2024. - 27 S. : Illustrationen
In: Cancers, ISSN 2072-6694. 16(2024), 7, Artikel-ID 1355, Seite 1-27
DOI: 10.3390/cancers16071355
- Grünewald, Thomas G. P.: Translational aspects of epithelioid sarcoma : current consensus / Thomas G.P. Grünewald, Sophie Postel-Vinay, Robert T. Nakayama, Noah E. Berlow, Andrea Bolzicco, Vin… , 15 March 2024. - 14 S. : Illustrationen
In: Clinical cancer research, ISSN 1557-3265. 30(2024), 6 vom: März, Seite 1079-1092
DOI: 10.1158/1078-0432.CCR-23-2174
- Musa, Julian: The GIST of it all : management of gastrointestinal stromal tumors (GIST) from the first steps to tailored therapy : a bibliometric analysis / Julian Musa, Sarah M. Kochendoerfer, Franziska Willis, Christine Sauerteig, Jonathan M. Harnoss, Ing… , 14 March 2024. - 9 S. : Illustrationen
In: Langenbeck's archives of surgery, ISSN 1435-2451. 409(2024), Artikel-ID 95, Seite 1-9
DOI: 10.1007/s00423-024-03271-6
- Lee, Olivia W.: Targeted long-read sequencing of the Ewing sarcoma 6p25.1 susceptibility locus identifies germline-somatic interactions with EWSR1-FLI1 binding / Olivia W. Lee, Calvin Rodrigues, Shu-Hong Lin, Wen Luo, Kristine Jones, Derek W. Brown, Weiyin Zhou,… , 2 March 2023. - 15 S.
In: The American journal of human genetics, ISSN 1537-6605. 110(2023), 3 vom: März, Seite 427-441
DOI: 10.1016/j.ajhg.2023.01.017
- Ceranski, Katharina: Hypoxia and HIFs in Ewing sarcoma : new perspectives on a multi-facetted relationship / A. Katharina Ceranski, Martha J. Carreño-Gonzalez, Anna C. Ehlers, Maria Vittoria Colombo, Florencia… , 13 March 2023. - 15 S. : Diagramme
In: Molecular cancer, ISSN 1476-4598. 22(2023), Artikel-ID 49, Seite 1-15
DOI: 10.1186/s12943-023-01750-w
- Orth, Martin Franz: Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation / Martin F. Orth, Didier Surdez, Tobias Faehling, Anna C. Ehlers, Aruna Marchetto, Sandrine Grossetête… , December 6, 2022. - 28 S. : Illustrationen, Diagramme
In: Cell reports, ISSN 2211-1247. 41(2022), 10, Artikel-ID 111761, Seite 1-28
DOI: 10.1016/j.celrep.2022.111761
- Puerto-Camacho, Pilar: Endoglin and MMP14 contribute to ewing sarcoma spreading by modulation of cell-matrix interactions / Pilar Puerto-Camacho, Juan Díaz-Martín, Joaquín Olmedo-Pelayo, Alfonso Bolado-Carrancio, Carmen Salg… , 4 August 2022. - 19 S.
In: International journal of molecular sciences, ISSN 1422-0067. 23(2022), 15, Artikel-ID 8657, Seite 1-19
DOI: 10.3390/ijms23158657
- Rasmussen, Samuel: Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology / Samuel V. Rasmussen, Jia xiang Jin, Lissett R. Bickford, Andrew D. Woods, Felix Sahm, Kenneth A. Cra… , 15 July 2022. - 22 S.
In: Clinical and translational medicine, ISSN 2001-1326. 12(2022), 7 vom: Juli, Artikel-ID e961, Seite 1-22
DOI: 10.1002/ctm2.961
- Sipol, Alexandra: MondoA drives malignancy in B-ALL through enhanced adaptation to metabolic stress / Alexandra Sipol, Erik Hameister, Busheng Xue, Julia Hofstetter, Maxim Barenboim, Rupert Öllinger, Ga… , February 24, 2022. - 14 S.
In: Blood, ISSN 1528-0020. 139(2022), 8, Seite 1184-1197
DOI: 10.1182/blood.2020007932
- Cidre-Aranaz, Florencia: Small round cell sarcomas / Florencia Cidre-Aranaz, Sarah Watson, James F. Amatruda, Takuro Nakamura, Olivier Delattre, Enrique … , 06 October 2022. - 22 S.
In: Nature reviews, ISSN 2056-676X. 8(2022) vom: Okt., Artikel-ID 66, Seite 1-22
DOI: 10.1038/s41572-022-00393-3
- Hölting, Tilman: Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma / Tilman L.B. Hölting, Florencia Cidre-Aranaz, Dana Matzek, Bastian Popper, Severin J. Jacobi, Corneli… , 13 October 2022
In: Molecular cancer, ISSN 1476-4598. 21(2022), Artikel-ID 199, Seite 1-11
DOI: 10.1186/s12943-022-01641-6
- Shulman, David S.: An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma / David S. Shulman, Sarah B. Whittle, Didier Surdez, Kelly M. Bailey, Enrique de Álava, Jason T. Yuste… , 17 September 2022. - 11 S.
In: npj precision oncology, ISSN 2397-768X. 6(2022), Artikel-ID 65, Seite 1-11
DOI: 10.1038/s41698-022-00307-2
- Völtzke, Kai Philipp: EIF4EBP1 is transcriptionally upregulated by MYCN and associates with poor prognosis in neuroblastoma / Kai Voeltzke, Katerina Scharov, Cornelius Maximilian Funk, Alisa Kahler, Daniel Picard, Laura Hauffe… , 04 April 2022. - 12 S.
In: Cell death discovery, ISSN 2058-7716. 8(2022), Artikel-ID 157, Seite 1-12
DOI: 10.1038/s41420-022-00963-0
- Vibert, Julien: Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions / Julien Vibert, Olivier Saulnier, Céline Collin, Floriane Petit, Kyra J. E. Borgman, Jérômine Vigneau… , July 7, 2022. - 3 S.
In: Molecular cell, ISSN 1097-4164. 82(2022), 13, Seite 2458-2471
DOI: 10.1016/j.molcel.2022.04.019
- Berthold, Ruth: Fusion protein-driven IGF-IR/PI3K/AKT signals deregulate Hippo pathway promoting oncogenic cooperation of YAP1 and FUS-DDIT3 in myxoid liposarcoma / Ruth Berthold, Ilka Isfort, Cihan Erkut, Lorena Heinst, Inga Grünewald, Eva Wardelmann, Thomas Kindl… , 22 April 2022. - 12 S.
In: Oncogenesis, ISSN 2157-9024. 11(2022), 1, Artikel-ID 20, Seite 1-12
DOI: 10.1038/s41389-022-00394-7
- Deng, Qu: Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1 / Qu Deng, Ramakrishnan Natesan, Florencia Cidre-Aranaz, Shehbeel Arif, Ying Liu, Reyaz ur Rasool, Pei… , 14 June 2022. - 26 S.
In: Cell reports, ISSN 2211-1247. 39(2022), 11, Artikel-ID 110971, Seite 1-26
DOI: 10.1016/j.celrep.2022.110971
- Rossi, Matteo: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis / Matteo Rossi, Patricia Altea-Manzano, Margherita Demicco, Ginevra Doglioni, Laura Bornes, Marina Fuk… , 2022. - 7 S.
In: Nature, ISSN 1476-4687. 605(2022), 7911, Seite 747-753
DOI: 10.1038/s41586-022-04758-2
- Hruby, Laura: Eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) expression in glioblastoma is driven by ETS1- and MYBL2-dependent transcriptional activation / Laura Hauffe, Daniel Picard, Julian Musa, Marc Remke, Thomas G.P. Grünewald, Barak Rotblat, Guido Re… , 28 February 2022. - 11 S.
In: Cell death discovery, ISSN 2058-7716. 8(2022), 1, Seite 1-11
DOI: 10.1038/s41420-022-00883-z
- Cidre-Aranaz, Florencia: Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma / Florencia Cidre-Aranaz, Jing Li, Tilman L. B. Hölting, Martin F. Orth, Roland Imle, Stefanie Kutschm… , 02 January 2022. - 7 S.
In: Molecular cancer, ISSN 1476-4598. 21(2022), Artikel-ID 1, Seite 1-7
DOI: 10.1186/s12943-021-01470-z
- Grünewald, Thomas G. P.: Erratum zu: Integrative Molekularpathologie von Krebserkrankungen / Redaktion „Der Pathologe“, 2. März 2021. - 1 S.
In: Der Pathologe, ISSN 1432-1963. 42(2021), 2 vom: März, Seite 252
DOI: 10.1007/s00292-021-00928-7
- García-García, Laura: The transcription factor FEZF1, a direct target of EWSR1-FLI1 in Ewing sarcoma cells, regulates the expression of neural-specific genes / Laura García-García, Enrique Fernández-Tabanera, Saint T. Cervera, Raquel M. Melero-Fernández de Mer… , 12 November 2021. - 18 S.
In: Cancers, ISSN 2072-6694. 13(2021), 22, Artikel-ID 5668, Seite 1-18
DOI: 10.3390/cancers13225668
- Solé Ferré, Anna: Unraveling Ewing sarcoma tumorigenesis originating from patient-derived mesenchymal stem cells / Anna Sole, Sandrine Grossetête, Maxime Heintzé, Loelia Babin, Sakina Zaïdi, Patrick Revy, Benjamin R… , August 2, 2021. - 13 S.
In: Cancer research, ISSN 1538-7445. 81(2021), 19, Seite 4994-5006
DOI: 10.1158/0008-5472.CAN-20-3837
- Ohmura, Shunya: Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma / Shunya Ohmura, Aruna Marchetto, Martin F. Orth, Jing Li, Susanne Jabar, Andreas Ranft, Endrit Vinca,… , 27 July 2021. - 7 S.
In: Molecular cancer, ISSN 1476-4598. 20(2021), Artikel-ID 97, Seite 1-7
DOI: 10.1186/s12943-021-01393-9
- Li, Jing: Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer / Jing Li, Shunya Ohmura, Aruna Marchetto, Martin F. Orth, Roland Imle, Marlene Dallmayer, Julian Musa… , 16 September 2021. - 12 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 5356, Seite 1-12
DOI: 10.1038/s41467-021-25553-z
- Rinaldi, Gianmarco: In vivo evidence for serine biosynthesis-defined sensitivity of lung metastasis, but not of primary breast tumors, to mTORC1 inhibition / Gianmarco Rinaldi, Erica Pranzini, Joke Van Elsen, Dorien Broekaert, Cornelius M. Funk, Mélanie Plan… , 2021. - 19 S.
In: Molecular cell, ISSN 1097-4164. 81(2021), 2, Seite 386-397,e1-e7
DOI: 10.1016/j.molcel.2020.11.027
- Broadfield, Lindsay A.: Fat induces glucose metabolism in nontransformed liver cells and promotes liver tumorigenesis / Lindsay A. Broadfield, João André Gonçalves Duarte, Roberta Schmieder, Dorien Broekaert, Koen Veys, … , March 9, 2021. - 14 S.
In: Cancer research, ISSN 1538-7445. 81(2021), 8, Seite 1988-2001
DOI: 10.1158/0008-5472.CAN-20-1954
- Zöllner, Stefan K.: Ewing sarcoma : diagnosis, treatment, clinical challenges and future perspectives / Stefan K. Zöllner, James F. Amatruda, Sebastian Bauer, Stéphane Collaud, Enrique de Álava, Steven G.… , 14 April 2021. - 59 S.
In: Journal of Clinical Medicine, ISSN 2077-0383. 10(2021), 8, Artikel-ID 1685, Seite 1-59
DOI: 10.3390/jcm10081685
- Jansky, Selina: Single-cell transcriptomic analyses provide insights into the developmental origins of neuroblastoma / Selina Jansky, Ashwini Kumar Sharma, Verena Körber, Andrés Quintero, Umut H. Toprak, Elisa M. Wecht,… , 25 March 2021. - 11 S.
In: Nature genetics, ISSN 1546-1718. 53(2021), 5, Seite 683-693
DOI: 10.1038/s41588-021-00806-1
- Kölsche, Christian: Sarcoma classification by DNA methylation profiling / Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam… , 21 January 2021. - 10 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 498, Seite 1-10
DOI: 10.1038/s41467-020-20603-4
- Gartlgruber, Moritz: Super enhancers define regulatory subtypes and cell identity in neuroblastoma / Moritz Gartlgruber, Ashwini Kumar Sharma, Andrés Quintero, Daniel Dreidax, Selina Jansky, Young-Gyu … , 2021. - 15 S.
In: Nature cancer, ISSN 2662-1347. 2(2021), 1, Seite 114-128
DOI: 10.1038/s43018-020-00145-w
- Grünewald, Thomas G. P.: Integrative Molekularpathologie von Krebserkrankungen / Thomas G.P. Grünewald, 2. Dezember 2020. - 3 S.
In: Der Pathologe, ISSN 1432-1963. 41(2020), Suppl 2 vom: Dez., Seite S67-S69
DOI: 10.1007/s00292-020-00870-0
- Fahr, Lisa: Expression of the EWSR1-FLI1 fusion oncogene in pancreas cells drives pancreatic atrophy and lipomatosis / Lisa Fahr, Yoshiaki Sunami, Nadja Maeritz, Katja Steiger, Thomas G.P. Grünewald, Martin Gericke, Bo … , 2020. - 9 S. : Illustrationen, Diagramme
In: Pancreatology, ISSN 1424-3911. 20(2020), 8, Seite 1673-1681
DOI: 10.1016/j.pan.2020.10.033
- Marchetto, Aruna: Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma / Aruna Marchetto, Shunya Ohmura, Martin F. Orth, Maximilian M.L. Knott, Maria V. Colombo, Chiara Arri… , 15 May 2020. - 16 S.
In: Nature Communications, ISSN 2041-1723. 11(2020), Artikel-ID 2423, Seite 1-16
DOI: 10.1038/s41467-020-16244-2
- Grünewald, Thomas G. P.: Sarcoma treatment in the era of molecular medicine / Thomas G.P Grünewald, Marta Alonso, Sofia Avnet, Ana Banito, Stefan Burdach, Florencia Cidre-Aranaz,… , 13 October 2020. - 33 S.
In: EMBO molecular medicine, ISSN 1757-4684. 12(2020), 11, Artikel-ID e11131, Seite 1-33
DOI: 10.15252/emmm.201911131
- Lin, Shu-Hong: Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma / Shu-Hong Lin, Joshua N. Sampson, Thomas G.P. Grünewald, Didier Surdez, Stephanie Reynaud, Olivier Mi… , September 3, 2020. - 12 S.
In: PLOS ONE, ISSN 1932-6203. 15(2020,9) Artikel-Nummer e0237792, 12 Seiten
DOI: 10.1371/journal.pone.0237792
- Schober, Sebastian J.: MHC class i-restricted TCR-transgenic CD4+ T cells against STEAP1 mediate local tumor control of ewing sarcoma in vivo / Sebastian J. Schober, Melanie Thiede, Hendrik Gassmann, Carolin Prexler, Busheng Xue, David Schirmer… , 29 June 2020. - 16 S.
In: Cells, ISSN 2073-4409. 9(2020,7) Artikel-Nummer 1581, 16 Seiten
DOI: 10.3390/cells9071581
- Orth, Martin Franz: High specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG positive ewing sarcoma / Martin F. Orth, Tilman L.B. Hölting, Marlene Dallmayer, Fabienne S. Wehweck, Tanja Paul, Julian Musa… , 10 March 2020. - 17 S.
In: Cancers, ISSN 2072-6694. 12(2020,3) Artikel-Nummer 644, 17 Seiten
DOI: 10.3390/cancers12030644
- Triki, Mouna: mTOR signaling and SREBP activity increase FADS2 expression and can activate sapienate biosynthesis / Mouna Triki, Gianmarco Rinaldi, Melanie Planque, Dorien Broekaert, Alina M. Winkelkotte, Carina R. M… , June 23, 2020. - 16 S.
In: Cell reports, ISSN 2211-1247. 31(2020,12) Artikel-Nummer 107806, 16 Seiten
DOI: 10.1016/j.celrep.2020.107806
- Kommoss, Felix: DNA methylation-based profiling of uterine neoplasms : a novel tool to improve gynecologic cancer diagnostics / Felix K. F. Kommoss, Damian Stichel, Daniel Schrimpf, Mark Kriegsmann, Basile Tessier-Cloutier, Alin… , 2020. - 8 S.
In: Journal of cancer research and clinical oncology, ISSN 1432-1335. 146(2020), 1, Seite 97-104
DOI: 10.1007/s00432-019-03093-w
- Jones, David T. W.: Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours / David T.W. Jones, Ana Banito, Thomas G.P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Til… , 12 July 2019. - 19 S.
In: Nature reviews, ISSN 1474-1768. 19(2019), 8, Seite 420-438
DOI: 10.1038/s41568-019-0169-x
- Tränka, Christopher: Role of LIM and SH3 Protein 1 (LASP1) in the Metastatic Dissemination of Medulloblastoma / Christopher Traenka, Marc Remke, Andrey Korshunov, Sebastian Bender, Thomas Hielscher, Paul A. North… , October 13 2010. - 12 S.
In: Cancer research, ISSN 1538-7445. 70(2010), 20, Seite 8003-8014
DOI: 10.1158/0008-5472.CAN-10-0592
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