
Halama, Niels Dr. med.Universität HeidelbergHeidelberg
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Co-Autoren (Uni Heidelberg)
- Valous, Nektarios A. (10)
- Springfeld, Christoph (10)
- Kloor, Matthias (10)
- Kahlert, Christoph (10)
- Schirmacher, Peter (9)
- Brenner, Hermann (9)
- Lahrmann, Bernd (9)
- Suarez-Carmona, Meggy (9)
- Schmidt, Thomas (9)
- Hoffmeister, Michael (9)
- Chang-Claude, Jenny (8)
- Kather, Jakob Nikolas (8)
- Büchler, Markus W. (8)
- Schneider, Martin (8)
- Ahmed, Azaz (7)
- Benner, Axel (7)
- Beckhove, Philipp (7)
- Koch, Moritz (1970-2015) (7)
- Giese, Nathalia (6)
- Franz, Clemens (6)
- Hassel, Jessica C. (6)
- Lasitschka, Felix (6)
- Krisam, Johannes (5)
- Jansen, Lina (5)
- Klotz, Rosa (5)
- Berthel, Anna (5)
- Hackert, Thilo (5)
- Rahbari, Nuh Nabi (5)
- Haag, Georg Martin (5)
- Brand, Karsten (5)
- Schneeweiss, Andreas (4)
- Rojas-Moraleda, Rodrigo (4)
- Charoentong, Pornpimol (4)
- (weitere Einträge vorhanden...)
Co-Autoren (extern)
- Penault-Llorca, Frederique (2)
- Spille, Anna (2)
- Koch, Moritz Philipp (1)
- Mohr, Jutta (1)
- Blay, Jean-Yves (1)
- Kunz, Christina (1)
- Seibel, Tobias Julian (1)
- Bonertz, Andreas (1)
- Bläker, Hendrik (1)
- Seibold, Petra Beate (1)
- Faryna, Marta (1)
- Chan, Andrew T. (1)
- Floßdorf, Michael (1)
- Xydia, Maria (1)
- Miller, Matthias (1)
- Gardyan, Adriane (1)
- Figueiredo, Jane C. (1)
- Papageorgiou, Ismini E. (1)
- Lopez Perez, Ramon (1)
- Möhler, Markus (1)
- Mahalingam, Devalingam (1)
- Frankish, Jamie (1)
- Califano, Andrea (1)
- Hornuß, Daniel (1)
- Plaumann, Julian (1)
- Bonvalot, Sylvie (1)
- Weitz, Juergen (1)
- Pecqueux, Mathieu (1)
- Kahlert, Christoph (1)
- Baumann, Matthias (1)
- Mazzone, Massimiliano (1)
- Gallagher, William M. (1)
- Jiao, Xuanmao (1)
- (weitere Einträge vorhanden...)
Publikationen in heiBIB 
- Fellhofer-Hofer, Johanna: Chemokines as prognostic factor in colorectal cancer patients : a systematic review and meta-analysis / Johanna Fellhofer-Hofer, Clemens Franz, Johannes A. Vey, Christoph Kahlert, Eva Kalkum, Arianeb Mehr… , 15 May 2024. - 14 S. : Illustrationen
In: International journal of molecular sciences, ISSN 1422-0067. 25(2024), 10, Artikel-ID 5374, Seite 1-14
DOI: 10.3390/ijms25105374
- Wankhede, Durgesh: Clinical significance of combined tumour-infiltrating lymphocytes and microsatellite instability status in colorectal cancer : a systematic review and network meta-analysis / Durgesh Wankhede, Tanwei Yuan, Matthias Kloor, Niels Halama, Hermann Brenner, Michael Hoffmeister, 9 May 2024. - 11 S. : Illustrationen
In: The lancet, ISSN 2468-1156. 9(2024), 7 vom: Juli, Seite 609-619
DOI: 10.1016/S2468-1253(24)00091-8
- Jahangir, Chowdhury Arif: Image-based multiplex immune profiling of cancer tissues : translational implications : a report of the International Immuno-oncology Biomarker Working Group on Breast Cancer / Chowdhury Arif Jahangir, David B Page, Glenn Broeckx, Claudia A Gonzalez, Caoimbhe Burke, Clodagh Mu… , March 2024. - 18 S. : Illustrationen
In: The journal of pathology, ISSN 1096-9896. 262(2024), 3 vom: März, Seite 271-288
DOI: 10.1002/path.6238
- Halama, Niels: Das bisher kleinste Taschenmesser für die Medizin / Niels Halama, 2024. - 4 S. : Illustrationen
In: Heilkunst Reloaded. (2024), Seite 312-315
- Zhang, Xin-Wen: Analysis of an unselected patient cohort with advanced colorectal carcinoma from a maximum care center / Xin-Wen Zhang, Jutta Mohr, Niels Halama and Ronald Koschny, December 2023. - 8 S. : Illustrationen
In: Anticancer research, ISSN 1791-7530. 43(2023), 12, Seite 5589-5596
DOI: 10.21873/anticanres.16761
- Page, David: Spatial analyses of immune cell infiltration in cancer : current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer / David B Page, Glenn Broeckx, Chowdhury Arif Jahangir, Sara Verbandt, Rajarsi R Gupta, Jeppe Thagaard… , August 2023. - 19 S.
In: The journal of pathology, ISSN 1096-9896. 260(2023), 5 vom: Aug., Seite 514-532
DOI: 10.1002/path.6165
- Hamid, Rasha: The role and therapeutic targeting of CCR5 in breast cancer / Rasha Hamid, Mustafa Alaziz, Amanpreet S. Mahal, Anthony W. Ashton, Niels Halama, Dirk Jaeger, Xuanm… , 2023. - 19 S. : Illustrationen
In: Cells, ISSN 2073-4409. 12(2023), 18, Artikel-ID 2237, Seite 1-19
DOI: 10.3390/cells12182237
- Ahmed, Azaz: Sex differences in the systemic and local immune response of pancreatic cancer patients / Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäg… , 17 March 2023. - 14 S.
In: Cancers, ISSN 2072-6694. 15(2023), 6, Artikel-ID 1815, Seite 1-14
DOI: 10.3390/cancers15061815
- Zhang, Xin-Wen: Cytokine alterations during paraneoplastic neutrophilia and leukemoid reaction in patients with advanced melanoma / Xin-Wen Zhang, Alexander Wald, Martin Salzmann, Niels Halama, Jessica C. Hassel, February 2023. - 5 S. : Illustrationen
In: Cancer immunology immunotherapy, ISSN 1432-0851. 72(2023), 2, Seite 509-513
DOI: 10.1007/s00262-022-03249-7
- Denkinger, Claudia M.: Anti-SARS-CoV-2 antibody-containing plasma improves outcome in patients with hematologic or solid cancer and severe COVID-19 : a randomized clinical trial / Claudia M. Denkinger, Maike Janssen, Ulrike Schäkel, Julia Gall, Albrecht Leo, Patrick Stelmach, Ste… , 2023. - 12 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 1, Seite 96-107
DOI: 10.1038/s43018-022-00503-w
- Fuchs, Juri: Generating evidence for diagnosis and therapy of RarE LIVEr disease : the RELIVE Initiative for systematic reviews and meta-analyses / Juri Fuchs, Anastasia Murtha-Lemekhova, Jan Pfeiffenberger, Alexander Fichtner, Patrick Günther, Nie… , 03 November 2022. - 3 S.
In: Systematic Reviews, ISSN 2046-4053. 11(2022), Artikel-ID 235, Seite 1-3
DOI: 10.1186/s13643-022-02105-0
- Walle, Thomas: Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 / Thomas Walle, Joscha A. Kraske, Boyu Liao, Bénédicte Lenoir, Carmen Timke, Emilia von Bohlen und Hal… , 23 Mar 2022. - 19 S.
In: Science advances, ISSN 2375-2548. 8(2022), 12, Artikel-ID eabh4050, Seite 1-19
DOI: 10.1126/sciadv.abh4050
- Ahmed, Azaz: Immune features of the peritumoral stroma in pancreatic ductal adenocarcinoma / Azaz Ahmed, Rosa Klotz, Sophia Köhler, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Dirk Jäg… , 05 September 2022. - 14 S.
In: Frontiers in immunology, ISSN 1664-3224. 13(2022), Artikel-ID 947407, Seite 1-14
DOI: 10.3389/fimmu.2022.947407
- Walle, Thomas: Cytokine release syndrome-like serum responses after COVID-19 vaccination are frequent and clinically inapparent under cancer immunotherapy / Thomas Walle, Sunanjay Bajaj, Joscha A. Kraske, Thomas Rösner, Christiane S. Cussigh, Katharina A. K… , 17 June 2022. - 13 S.
In: Nature cancer, ISSN 2662-1347. 3(2022), 9, Seite 1039-1051
DOI: 10.1038/s43018-022-00398-7
- Haag, Georg Martin: Pembrolizumab and maraviroc in refractory mismatch repair proficient/microsatellite-stable metastatic colorectal cancer : the PICCASSO phase I trial / Georg Martin Haag, Christoph Springfeld, Barbara Grün, Leonidas Apostolidis, Stefanie Zschäbitz, Mar… , 12 April 2022. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 167(2022), Seite 112-122
DOI: 10.1016/j.ejca.2022.03.017
- Neufeldt, Christopher: SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB / Christopher J. Neufeldt, Berati Cerikan, Mirko Cortese, Jamie Frankish, Ji-Young Lee, Agnieszka Ploc… , 2022 Jan 12. - 15 S.
In: Communications biology, ISSN 2399-3642. 5(2022), Artikel-ID 45, Seite 1-15
DOI: 10.1038/s42003-021-02983-5
- Panayotacopoulou, Maria: Microglia activation in the midbrain of the human neonate : the effect of perinatal hypoxic-ischemic injury / Maria T. Panayotacopoulou, PhD, Ismini Papageorgiou, MD, PhD, Marianna Pagida, PhD, Alexandra E. Kat… , 29 January 2022. - 7 S.
In: Journal of neuropathology and experimental neurology, ISSN 1554-6578. 81(2022), 3, Seite 208-224
DOI: 10.1093/jnen/nlab135
- Ahmed, Azaz: Tertiary lymphoid structures and their association to immune phenotypes and circulatory IL2 levels in pancreatic ductal adenocarcinoma / Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Thilo Hackert, Christoph Springfeld, Inka Zör… , 31 Jan 2022. - 10 S.
In: OncoImmunology, ISSN 2162-402X. 11(2022), 1, Artikel-ID 2027148, Seite 1-10
DOI: 10.1080/2162402X.2022.2027148
- Hajda, Jacek: Phase 2 trial of oncolytic H-1 parvovirus therapy shows safety and signs of immune system activation in patients with metastatic pancreatic ductal adenocarcinoma / Jacek Hajda, Barbara Leuchs, Assia L. Angelova, Veronika Frehtman, Jean Rommelaere, Mieke Mertens, M… , August 23, 2021. - 11 S.
In: Clinical cancer research, ISSN 1557-3265. 27(2021), 20, Seite 5546-5556
DOI: 10.1158/1078-0432.CCR-21-1020
- Suarez-Carmona, Meggy: Combined inhibition of CXCL12 and PD-1 in MSS colorectal and pancreatic cancer : modulation of the microenvironment and clinical effects / Meggy Suarez-Carmona, Anja Williams, Jutta Schreiber, Nicolas Hohmann, Ulrike Pruefer, Jürgen Krauss… , 2021. - 13 S.
In: Journal for ImmunoTherapy of Cancer, ISSN 2051-1426. 9(2021), 10, Artikel-ID e002505, Seite 1-13
DOI: 10.1136/jitc-2021-002505
- Ahmed, Azaz: Peripheral blood and tissue assessment highlights differential tumor-circulatory gradients of IL2 and MIF with prognostic significance in resectable pancreatic ductal adenocarcinoma / Azaz Ahmed, Sophia Köhler, Rosa Klotz, Nathalia Giese, Felix Lasitschka, Thilo Hackert, Christoph Sp… , 10 Aug 2021. - 9 S.
In: OncoImmunology, ISSN 2162-402X. 10(2021), 1, Artikel-ID 1962135, Seite 1-9
DOI: 10.1080/2162402X.2021.1962135
- Klupp, Fee: Granulin : an invasive and survival-determining marker in colorectal cancer patients / Fee Klupp, Christoph Kahlert, Clemens Franz, Niels Halama, Nikolai Schleussner, Naita M. Wirsik, Arn… , 16 June 2021. - 11 S.
In: International journal of molecular sciences, ISSN 1422-0067. 22(2021), 12, Artikel-ID 6436, Seite 1-11
DOI: 10.3390/ijms22126436
- Boakye, Daniel: The association of vitamin D with survival in colorectal cancer patients depends on antioxidant capacity / Daniel Boakye, Lina Jansen, Ben Schöttker, Eugene H J M Jansen, Niels Halama, Haifa Maalmi, Xin Gào,… , June 2021. - 10 S.
In: The American journal of clinical nutrition, ISSN 1938-3207. 113(2021), 6 vom: Juni, Seite 1458-1467
DOI: 10.1093/ajcn/nqaa405
- Machiraju, Devayani: Soluble immune checkpoints and T-cell subsets in blood as biomarkers for resistance to immunotherapy in melanoma patients / Devayani Machiraju, Melanie Wiecken, Nina Lang, Ingrid Hülsmeyer, Jasmin Roth, Timo E. Schank, Rosa … , 25 May 2021. - 13 S.
In: OncoImmunology, ISSN 2162-402X. 10(2021), Artikel-ID 1926762, Seite 1-13
DOI: 10.1080/2162402X.2021.1926762
- Boakye, Daniel: Early discontinuation and dose reduction of adjuvant chemotherapy in stage III colon cancer patients / Daniel Boakye, Lina Jansen, Niels Halama, Jenny Chang-Claude, Michael Hoffmeister and Hermann Brenne… , April 22, 2021. - 18 S.
In: Therapeutic advances in medical oncology, ISSN 1758-8359. 13(2021) vom: Jan., Artikel-ID 17588359211006348, Seite 1-18
DOI: 10.1177/17588359211006348
- Xydia, Maria: Common clonal origin of conventional T cells and induced regulatory T cells in breast cancer patients / Maria Xydia, Raheleh Rahbari, Eliana Ruggiero, Iain Macaulay, Maxime Tarabichi, Robert Lohmayer, Ste… , 18 February 2021. - 18 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 1119, Seite 1-18
DOI: 10.1038/s41467-021-21297-y
- Klupp, Fee: Evaluation of the inflammatory markers CCL8, CXCL5, and LIF in patients with anastomotic leakage after colorectal cancer surgery / F. Klupp, S. Schuler, C. Kahlert, N. Halama, C. Franz, P. Mayer, T. Schmidt, A. Ulrich, 19 April 2020. - 10 S.
In: International journal of colorectal disease, ISSN 1432-1262. 35(2020), 7, Seite 1221-1230
DOI: 10.1007/s00384-020-03582-2
- Neumeyer, Sonja: Genetic variants in the regulatory T cell-related pathway and colorectal cancer prognosis / Sonja Neumeyer, Xinwei Hua, Petra Seibold, Lina Jansen, Axel Benner, Barbara Burwinkel, Niels Halama… , October 2, 2020. - 10 S.
In: Cancer epidemiology, biomarkers & prevention, ISSN 1538-7755. 29(2020), 12, Seite 2719-2728
DOI: 10.1158/1055-9965.EPI-20-0714
- Rojas-Moraleda, Rodrigo: Segmentation of biomedical images based on a computational topology framework / Rodrigo Rojas Moraleda, Wei Xiong, Nektarios A. Valous, Niels Halama, 2 December 2020. - 7 S.
In: Seminars in immunology, ISSN 1096-3618. 48(2020,1) Artikel-Nummer 101432, 7 Seiten
DOI: 10.1016/j.smim.2020.101432
- Ahmed, Azaz: Differential analyses of peripheral blood parameters in CCR5 inhibition-treated colorectal cancer patients reveal dynamic changes linked to clinical outcomes / Azaz Ahmed and Niels Halama, December 7, 2020. - 7 S.
In: Anticancer research, ISSN 1791-7530. 40(2020), 12, Seite 6933-6939
DOI: 10.21873/anticanres.14717
- Valous, Nektarios A.: Interrogating the microenvironmental landscape of tumors with computational image analysis approaches / Nektarios A. Valous, Rodrigo Rojas Moraleda, Dirk Jäger, Inka Zörnig, Niels Halama, 6 November 2020. - 12 S.
In: Seminars in immunology, ISSN 1096-3618. 48(2020) Artikel-Nummer 101411, 12 Seiten
DOI: 10.1016/j.smim.2020.101411
- Ahmed, Azaz: Tertiary lymphoid structures in colorectal cancer liver metastases : association with immunological and clinical parameters and chemotherapy response / Azaz Ahmed and Niels Halama, November 2020. - 7 S.
In: Anticancer research, ISSN 1791-7530. 40(2020), 11, Seite 6367-6373
DOI: 10.21873/anticanres.14657
- Janssen, Maike: A randomized open label phase-II clinical trial with or without infusion of plasma from subjects after convalescence of SARS-CoV-2 infection in high-risk patients with confirmed severe SARS-CoV-2 disease (RECOVER) : a structured summary of a study protocol for a randomised controlled trial / Maike Janssen, Ulrike Schäkel, Carine Djuka Fokou, Johannes Krisam, Jacek Stermann, Katharina Kriegs… , 06 October 2020. - 4 S.
In: Trials, ISSN 1468-6694. 21(2020), Artikel-ID 828, Seite 1-4
DOI: 10.1186/s13063-020-04735-y
- Halama, Niels: The Unmet Needs of the Diagnosis, Staging, and Treatment of Gastrointestinal Tumors / Niels Halama, and Uwe Haberkorn, 8 July 2020. - 10 S.
In: Seminars in nuclear medicine, ISSN 1558-4623. 50(2020), 5, Seite 389-398
DOI: 10.1053/j.semnuclmed.2020.06.003
- Jiao, Xuanmao: Recent advances targeting CCR5 for cancer and its role in immuno-oncology / Xuanmao Jiao, Omar Nawab, Tejal Patel, Andrew V. Kossenkov, Niels Halama, Dirk Jaeger, and Richard G… , July 10, 2019. - 7 S.
In: Cancer research, ISSN 1538-7445. 79(2019), 19, Seite 4801-4807
DOI: 10.1158/0008-5472.CAN-19-1167
- Klupp, Fee: E3 ubiquitin ligase Smurf2 : a prognostic factor in microsatellite stable colorectal cancer / Fee Klupp, Christina Giese, Niels Halama, Clemens Franz, Felix Lasitschka, Arne Warth, Thomas Schmid… , 22 February 2019. - 9 S.
In: Cancer management and research, ISSN 1179-1322. (2019), Seite 1795-1803
- Halama, Niels: Machine learning for tissue diagnostics in oncology : brave new world / Niels Halama, 09 August 2019. - 3 S.
In: British journal of cancer, ISSN 1532-1827. 121(2019), 6, Seite 431-433
DOI: 10.1038/s41416-019-0535-1
- Kather, Jakob Nikolas: Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer / Jakob Nikolas Kather, Alexander T. Pearson, Niels Halama, Dirk Jäger, Jeremias Krause, Sven H. Loose… , 3 June 2019. - 10 S.
In: Nature medicine, ISSN 1546-170X. 25(2019), 7, Seite 1054-1056,7
DOI: 10.1038/s41591-019-0462-y
- Kather, Jakob Nikolas: Harnessing the innate immune system and local immunological microenvironment to treat colorectal cancer / Jakob Nikolas Kather, Niels Halama, 02 April 2019. - 12 S.
In: British journal of cancer, ISSN 1532-1827. 120(2019), 9, Seite 871-882
DOI: 10.1038/s41416-019-0441-6
- Fremd, Carlo: Mismatch repair deficiency drives durable complete remission by targeting programmed death receptor 1 in a metastatic luminal breast cancer patient / Carlo Fremd, Mario Hlevnjak, Marc Zapatka, Inka Zoernig, Niels Halama, Nino Fejzibegovic, Verena The… , 2019. - 7 S.
In: Breast care, ISSN 1661-3805. 14(2019), 1, Seite 53-59
DOI: 10.1159/000492580
- Kather, Jakob Nikolas: Predicting survival from colorectal cancer histology slides using deep learning : a retrospective multicenter study / Jakob Nikolas Kather, Johannes Krisam, Pornpimol Charoentong, Tom Luedde, Esther Herpel, Cleo-Aron W… , January 24, 2019. - 22 S.
In: PLoS medicine, ISSN 1549-1676. 16(2019,1) Artikel-Nummer e1002730, 22 Seiten
DOI: 10.1371/journal.pmed.1002730
- Saeedi, Mohammed al: Neutralization of CD95 ligand protects the liver against ischemia-reperfusion injury and prevents acute liver failure / Mohammed Al-Saeedi, Niels Steinebrunner, Hassan Kudsi, Niels Halama, Carolin Mogler, Markus W. Büchl… , 26 January 2018. - 9 S.
In: Cell death & disease, ISSN 2041-4889. 9(2018,2) Artikel-Nummer 132, 9 Seiten
DOI: 10.1038/s41419-017-0150-0
- Plaumann, Julian: IL-10 inducible CD8+ regulatory T-cells are enriched in patients with multiple myeloma and impact the generation of antigen-specific T-cells / Julian Plaumann, Melanie Engelhardt, Mohamed H. S. Awwad, Hakim Echchannaoui, Eva Amman, Marc S. Raa… , 20 August 2018. - 13 S.
In: Cancer immunology immunotherapy, ISSN 1432-0851. 67(2018), 11, Seite 1695-1707
DOI: 10.1007/s00262-018-2230-0
- Michels, Judith: Multiplex bead-based measurement of humoral immune responses against tumor-associated antigens in stage II melanoma patients of the EORTC18961 trial / Judith Michels, Natalia Becker, Stefan Suciu, Iris Kaiser, Axel Benner, Zeynep Kosaloglu-Yalcin, San… , 12 February 2018. - 10 S.
In: OncoImmunology, ISSN 2162-402X. 7(2018,6) Artikel-Nummer e1428157, 10 Seiten
DOI: 10.1080/2162402X.2018.1428157
- Valous, Nektarios A.: Multilacunarity as a spatial multiscale multi-mass morphometric of change in the meso-architecture of plant parenchyma tissue / N.A. Valous, W. Xiong, N. Halama, I. Zörnig, D. Cantre, Z. Wang, B. Nicolai, P. Verboven, and R. Roj… , 20 September 2018. - 8 S.
In: Chaos, ISSN 1089-7682. 28(2018,9) Artikel-Nummer 093110, 8 Seiten
DOI: 10.1063/1.5047021
- Papageorgiou, Ismini E.: Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus / Ismini E. Papageorgiou, Nektarios A. Valous, Bernd Lahrmann, Hana Janova, Zin-Juan Klaft, Arend Koch… , 19 January 2018. - 14 S. : Illustrationen
In: Glia, ISSN 1098-1136. 66(2018), 5, Seite 920-933
DOI: 10.1002/glia.23292
- Kather, Jakob Nikolas: High-throughput screening of combinatorial immunotherapies with patient-specific in silico models of metastatic colorectal cancer / Jakob Nikolas Kather, Pornpimol Charoentong, Meggy Suarez-Carmona, Esther Herpel, Fee Klupp, Alexis … , July 2, 2018. - 9 S.
In: Cancer research, ISSN 1538-7445. 78(2018), 17, Seite 5155-5163
DOI: 10.1158/0008-5472.CAN-18-1126
- Kather, Jakob Nikolas: Genomics and emerging biomarkers for immunotherapy of colorectal cancer / Jakob Nikolas Kather, Niels Halama, Dirk Jaeger, 1 March 2018. - 9 S.
In: Seminars in cancer biology, ISSN 1096-3650. 52(2018), Seite 189-197
DOI: 10.1016/j.semcancer.2018.02.010
- Kather, Jakob Nikolas: Large-scale database mining reveals hidden trends and future directions for cancer immunotherapy / Jakob Nikolas Kather, Anna Sophie Berghoff, Dyke Ferber, Meggy Suarez-Carmona, Constantino Carlos Re… , 29 Mar 2018. - 8 S.
In: OncoImmunology, ISSN 2162-402X. 7(2018,7) Artikel-Nummer e1444412, 8 Seiten
DOI: 10.1080/2162402X.2018.1444412
- Haag, Georg Martin: Phase II trial of ipilimumab in melanoma patients with preexisting humoural immune response to NY-ESO-1 / G. M. Haag, I. Zoernig, J. C. Hassel, N. Halama, J. Dick, N. Lang, L. Podola, J. Funk, C. Ziegelmeie… , 5 January 2018. - 8 S.
In: European journal of cancer, ISSN 1879-0852. 90(2018), Seite 122-129
DOI: 10.1016/j.ejca.2017.12.001
- Halama, Niels: The next age of immunotherapy : optimisation, stratification and therapeutic synergies / Niels Halama, 2019. - 2 S.
In: British journal of cancer, ISSN 1532-1827. 120(2019), 1, Seite 1-2
DOI: 10.1038/s41416-018-0330-4
- Kather, Jakob Nikolas: Topography of cancer-associated immune cells in human solid tumors / Jakob Nikolas Kather, Meggy Suarez-Carmona, Pornpimol Charoentong, Cleo-Aron Weis, Daniela Hirsch, P… , 04 September 2018. - 19 S.
In: eLife, ISSN 2050-084X. 7(2018), Artikel-ID e36967
DOI: 10.7554/eLife.36967
- Halama, Niels: Charakterisierung der gewebeständigen immunologischen Tumormikroumgebung im metastasierten kolorektalen Karzinom / vorgelegt von Dr. med. Niels Halama. -
Heidelberg, 2017. - 1 Band (verschiedene Seitenzählungen) : Illustrationen, Diagramme
- Berthel, Anna: Detailed resolution analysis reveals spatial T cell heterogeneity in the invasive margin of colorectal cancer liver metastases associated with improved survival / Anna Berthel, Inka Zoernig, Nektarios A. Valous, Christoph Kahlert, Fee Klupp, Alexis Ulrich, Juerge… , 23 Feb 2017. - 11 S.
In: OncoImmunology, ISSN 2162-402X. 6(2017,3) Artikel-Nummer e1286436, 11 Seiten
DOI: 10.1080/2162402X.2017.1286436
- Hassel, Jessica C.: Tadalafil has biologic activity in human melanoma : results of a pilot trial with Tadalafil in patients with metastatic Melanoma (TaMe) / Jessica C. Hassel, Huanhuan Jiang, Carolin Bender, Julia Winkler, Alexandra Sevko, Ivan Shevchenko, … , 24 Aug 2017. - 10 S.
In: OncoImmunology, ISSN 2162-402X. 6(2017) Artikel-Nummer e1326440, 10 Seiten
DOI: 10.1080/2162402X.2017.1326440
- Kather, Jakob Nikolas: In silico modeling of immunotherapy and stroma-targeting therapies in human colorectal cancer / Jakob Nikolas Kather, Jan Poleszczuk, Meggy Suarez-Carmona, Johannes Krisam, Pornpimol Charoentong, … , September 18, 2017. - 11 S.
In: Cancer research, ISSN 1538-7445. 77(2017), 22, Seite 6442-6452
DOI: 10.1158/0008-5472.CAN-17-2006
- Hajda, Jacek: A non-controlled, single arm, open label, phase II study of intravenous and intratumoral administration of ParvOryx in patients with metastatic, inoperable pancreatic cancer: ParvOryx02 protocol / Jacek Hajda; Monika Lehmann; Ottheinz Krebs; Meinhard Kieser; Karsten Geletneky; Dirk Jäger; Michael… . -
London; Berlin; Heidelberg: BioMed Central; Springer, 2017. - 1 Online-Ressource
DOI: 10.1186/s12885-017-3604-y
- Rojas-Moraleda, Rodrigo: Robust detection and segmentation of cell nuclei in biomedical images based on a computational topology framework / Rodrigo Rojas-Moraleda, Wei Xiong, Niels Halama, Katja Breitkopf-Heinlein, Steven Dooley, Luis Salin… , 6 March 2017. - 14 S.
In: Medical image analysis, ISSN 1361-8423. 38(2017), Seite 90-103
DOI: 10.1016/j.media.2017.02.009
- Fricke, Fabia: TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells / Fabia Fricke; Jennifer Lee; Malwina Michalak; Uwe Warnken; Ingrid Haußer; Meggy Suarez-Carmona; Niel… . -
London: BioMed Central, 2017. - 1 Online-Ressource
DOI: 10.1186/s12964-017-0169-y
- Fricke, Fabia: TGFBR2-dependent alterations of exosomal cargo and functions in DNA mismatch repair-deficient HCT116 colorectal cancer cells / Fabia Fricke, Jennifer Lee, Malwina Michalak, Uwe Warnken, Ingrid Hausser, Meggy Suarez-Carmona, Nie… , 4 April 2017
In: Cell communication and signaling, ISSN 1478-811X. 15(2017) Artikel-Nummer 14, 14 Seiten
DOI: 10.1186/s12964-017-0169-y
- Poschke, Isabel: Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma / Isabel Poschke, Marta Faryna, Frank Bergmann, Michael Flossdorf, Claudia Lauenstein, Jennifer Hermes… , 29 Nov 2016. - 12 S.
In: OncoImmunology, ISSN 2162-402X. 5(2016,12), Artikel-Nummer e1240859, 12 Seiten
DOI: 10.1080/2162402X.2016.1240859
- Koşaloğlu, Zeynep: Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases / Zeynep Koşaloğlu, Inka Zörnig, Niels Halama, Iris Kaiser, Ivo Buchhalter, Niels Grabe, Roland Eils, … , 04 Nov 2016. - 11 S.
In: OncoImmunology, ISSN 2162-402X. 5(2016,11) Artikel-Nummer e1213931, 11 Seiten
DOI: 10.1080/2162402X.2016.1213931
- Jäger, Dirk: Immunotherapy of colorectal cancer / Dirk Jäger, Niels Halama, Inka Zörnig, Paula Klug, Jürgen Krauss, Georg-Martin Haag. -
Basel: Karger, 24 Okt. 2019. - 1 Online-Ressource (4 Seiten)
DOI: 10.11588/heidok.00027245
- Möhler, Markus: Immunotherapy in gastrointestinal cancer : Recent results, current studies and future perspectives / Markus Moehler, Maike Delic, Katrin Goepfert, Daniela Aust, Heike I. Grabsch, Niels Halama, Bernd He… , 31 March 2016. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 59(2016), Seite 160-170
DOI: 10.1016/j.ejca.2016.02.020
- Jäger, Dirk: Immunotherapy of colorectal cancer / Dirk Jäger, Niels Halama, Inka Zörnig, Paula Klug, Jürgen Krauss, Georg-Martin Haag, May 25, 2016. - 4 S.
In: Oncology research and treatment, ISSN 2296-5262. 39(2016), 6, Seite 347-350
DOI: 10.1159/000446713
- Valous, Nektarios A.: Spatial intratumoral heterogeneity of proliferation in immunohistochemical images of solid tumors / Nektarios A. Valous, Bernd Lahrmann, Niels Halama, Frank Bergmann, Dirk Jäger, Niels Grabe, 17 May 2016. - 12 S.
In: Medical physics, ISSN 2473-4209. 43(2016), 6, Seite 2936-2947
DOI: 10.1118/1.4949003
- Rusakiewicz, Sylvie: NKp30 isoforms and NKp30 ligands are predictive biomarkers of response to imatinib mesylate in metastatic GIST patients / Sylvie Rusakiewicz, Aurélie Perier, Michaela Semeraro, Jonathan M. Pitt, Elke Pogge von Strandmann, … , 2017. - 13 S.
In: OncoImmunology, ISSN 2162-402X. Artikel-Nummer e1137418, 13 Seiten
DOI: 10.1080/2162402X.2015.1137418
- Halama, Niels: CCR5 inhibition in colorectal cancer patients / Niels Halama, 29 June 2016. - 2 S.
In: Translational cancer research, ISSN 2219-6803. 5(2016), 2, Seite S366-S367
DOI: 10.21037/tcr.2016.07.42
- Mahalingam, Devalingam: Anti-oxidized macrophage migration inhibitory factor (oxMIF) antibody imalumab (BAX69) in advanced solid tumors : Final results of first-in-human phase 1 study / D. Mahalingam, M.R. Patel, J.C. Sachdev, L.L. Hart, N. Halama, R.K. Ramanathan, J. Sarantopoulos, X.… , 16 October 2016
In: Annals of oncology, ISSN 1569-8041. 27(2016,Supplement 6) Artikel-Nummer 365PD, 1 Seite
DOI: 10.1093/annonc/mdw368.08
- Koşaloğlu, Zeynep: In silico SNP analysis of the breast cancer antigen NY-BR-1 / Zeynep Kosaloglu, Julia Bitzer, Niels Halama, Zhiqin Huang, Marc Zapatka, Andreas Schneeweiss, Dirk … . -
London; Berlin; Heidelberg: BioMed Central, 18 November 2016. - 1 Online-Ressource (12 Seiten)
DOI: 10.1186/s12885-016-2924-7
- Klupp, Fee: Serum MMP7, MMP10 and MMP12 level as negative prognostic markers in colon cancer patients / Fee Klupp; Lena Neumann; Christoph Kahlert; Johannes Diers; Niels Halama; Clemens Franz; Thomas Schm… . -
London; Berlin; Heidelberg: BioMed Central; Springer, 18 July 2016. - 1 Online-Ressource
DOI: 10.1186/s12885-016-2515-7
- Halama, Niels: Tumoral immune cell exploitation in colorectal cancer metastases can be targeted effectively by anti-CCR5 therapy in cancer patients / Niels Halama, Inka Zoernig, Anna Berthel, Christoph Kahlert, Fee Klupp, Meggy Suarez-Carmona, Thomas… , April 11, 2016. - 15 S.
In: Cancer cell, ISSN 1878-3686. 29(2016), 4, Seite 587-601
DOI: 10.1016/j.ccell.2016.03.005
- Klupp, Fee: Expressional STAT3/STAT5 ratio is an independent prognostic marker in colon carcinoma / Fee Klupp, Johannes Diers, Christoph Kahlert, Lena Neumann, Niels Halama, Clemens Franz, Thomas Schm… , 13 March 2015. - 8 S.
In: Annals of surgical oncology, ISSN 1534-4681. 22(2015), 3, Seite 1548-1555
DOI: 10.1245/s10434-015-4485-4
- Reißfelder, Christoph: Corrigendum - Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis / Christoph Reissfelder, Slava Stamova, Christina Gossmann, Marion Braun, Andreas Bonertz, Ute Wallicz… , [March 2015]. - 1 S.
In: The journal of clinical investigation, ISSN 1558-8238. 125(2015), 3, Seite 1364
DOI: 10.1172/JCI81442
- Gardyan, Adriane: Identification of NY-BR-1-specific CD4+ T cell epitopes using HLA-transgenic mice / Adriane Gardyan, Wolfram Osen, Inka Zörnig, Lilli Podola, Maria Agarwal, Sebastian Aulmann, Eliana R… , 12 Nov 2014. - 10 S.
In: International journal of Cancer Studies & Research, ISSN 2167-9118. 136(2015), 11, Seite 2588-2597
DOI: 10.1002/ijc.29322
- Kiesgen, Stefan: An EGF receptor targeting Ranpirnase-diabody fusion protein mediates potent antitumour activity in vitro and in vivo : Stefan Kiesgen, Michaela A.E. Arndt, Christoph Körber, Ulrich Arnold, Tobias Weber, Niels Halama, Armin Keller, Benedikt Bötticher, Anne Schlegelmilch, Nora Liebers, Martin Cremer, Christel Herold-Mende, Gerhard Dyckhoff, Philippe A. Federspil, Alexandra D. Jensen, Dirk Jäger, Roland E. Kontermann, Walter Mier, Jürgen Krauss, 2015. - 10 S.
In: Cancer letters, ISSN 1872-7980. 357(2015), 1, Seite 364-373
DOI: 10.1016/j.canlet.2014.11.054
- Zörnig, Inka: Prognostic significance of spontaneous antibody responses against tumor-associated antigens in malignant melanoma patients / Inka Zörnig, Niels Halama, Justo Lorenzo Bermejo, Claudia Ziegelmeier, Elke Dickes, Alexander Migdol… , 1 January 2015. - 14 S.
In: International journal of cancer, ISSN 1097-0215. 136(2014), 1, Seite 138-151
DOI: 10.1002/ijc.28980
- Kahlert, Christoph: Prognostic impact of a compartment-specific angiogenic marker profile in patients with pancreatic cancer / Christoph Kahlert, Maria Fiala, Gabriel Musso, Niels Halama, Sophia Keim, Massimiliano Mazzone, Feli… , December 30, 2014. - 12 S.
In: OncoTarget, ISSN 1949-2553. 5(2014), 24, Seite 12978-12989
DOI: 10.18632/oncotarget.2651
- Kahlert, Christian: Tumour-site-dependent expression profile of angiogenic factors in tumour-associated stroma of primary colorectal cancer and metastases / C. Kahlert, M. Pecqueux, N. Halama, H. Dienemann, T. Muley, J. Pfannschmidt, F. Lasitschka, F. Klupp… , 2014. - 9 S.
In: British journal of cancer, ISSN 1532-1827. 110(2014), 2, Seite 441-449
DOI: 10.1038/bjc.2013.745
- Reißfelder, Christoph: Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis / Christoph Reissfelder ... Markus W. Büchler, Dirk Jäger, Niels Halama ..., 2014. - 13 S.
In: The journal of clinical investigation, ISSN 1558-8238. 124(2014), Seite ?
DOI: 10.1172/JCI74894
- Sherwood, Anna: Tumor-infiltrating lymphocytes in colorectal tumors display a diversity of T cell receptor sequences that differ from the T cells in adjacent mucosal tissue / Anna M. Sherwood, Ryan O. Emerson, Dominique Scherer, Nina Habermann, Katharina Buck, Jürgen Staffa,… , 2013. - 9 S.
In: Cancer immunology immunotherapy, ISSN 1432-0851. 62(2013), 9, Seite 1453-1461
DOI: 10.1007/s00262-013-1446-2
- Rusakiewicz, Sylvie: Immune infiltrates are prognostic factors in localized gastrointestinal stromal tumors / Sylvie Rusakiewicz, Michaela Semeraro, Matthieu Sarabi, Mélanie Desbois, Clara Locher, Rosa Mendez, … , April 16, 2013. - 12 S.
In: Cancer research, ISSN 1538-7445. 73(2013), 12 vom: Juni, Seite 3499-3510
DOI: 10.1158/0008-5472.CAN-13-0371
- Zörnig, Inka: Sequence mutations of the substrate binding pocket of stem cell factor and multidrug resistance protein ABCG2 in renal cell cancer : A possible link to treatment resistance / Inka Zoernig, Claudia Ziegelmeier, Bernd Lahrmann, Niels Grabe, Dirk Jäger, Niels Halama, March 5, 2013. - 4 S.
In: Oncology reports, ISSN 1791-2431. 29(2013), 5, Seite 1697-1700
DOI: 10.3892/or.2013.2324
- Klug, Felix: Low-dose irradiation programs macrophage differentiation to an iNOS+/M1 phenotype that orchestrates effective T cell immunotherapy / Felix Klug, Hridayesh Prakash, Peter E. Huber, Tobias Seibel, Noemi Bender, Niels Halama, Christina … , October 24, 2013. - 14 S.
In: Cancer cell, ISSN 1878-3686. 24(2013), 5, Seite 589-602
DOI: 10.1016/j.ccr.2013.09.014
- Halama, Niels: Hepatic metastases of colorectal cancer are rather homogeneous but differ from primary lesions in terms of immune cell infiltration / Niels Halama, Anna Spille, Tina Lerchl, Karsten Brand, Esther Herpel, Stefan Welte, Sophia Keim, Ber… , 01 Apr 2013. - 11 S.
In: OncoImmunology, ISSN 2162-402X. 2(2013,4) Artikel-Nummer e24116, 11 Seiten
DOI: 10.4161/onci.24116
- Großardt, Christian: Granulocyte-macrophage colony-stimulating factor-armed oncolytic measles virus is an effective therapeutic cancer vaccine / Christian Grossardt, Christine E. Engeland, Sascha Bossow, Niels Halama, Karim Zaoui, Mathias F. Leb… , 3 May 2013. - 11 S.
In: Human gene therapy, ISSN 1557-7422. 24(2013), 7, Seite 644-654
DOI: 10.1089/hum.2012.205
- Safferling, Kai: Wound healing revised : novel reepithelialization mechanism revealed by in vitro and in silico models / Kai Safferling, Thomas Sütterlin, Kathi Westphal, Claudia Ernst, Kai Breuhahn, Merlin James, Dirk Jä… , 2013. - 19 S.
In: The journal of cell biology, ISSN 1540-8140. 203(2013), 4, Seite 691-709
DOI: 10.1083/jcb.201212020
- Keim, Sophia: Sequential metastases of colorectal cancer : immunophenotypes and spatial distributions of infiltrating immune cells in relation to time and treatments / Sophia Keim, Inka Zoernig, Anna Spille, Bernd Lahrmann, Karsten Brand, Esther Herpel, Niels Grabe, D… , 24 Aug 2012. - 7 S.
In: OncoImmunology, ISSN 2162-402X. 1(2012), 5, Seite 593-599
DOI: 10.4161/onci.20179
- Kahlert, Christoph: Expression analysis of aldehyde dehydrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy / Christoph Kahlert, Eva Gaitzsch, Gunnar Steinert, Carolin Mogler, Esther Herpel, Michael Hoffmeister… , 10 August 2012. - 9 S.
In: Annals of surgical oncology, ISSN 1534-4681. 19(2012), 13, Seite 4193-4201
DOI: 10.1245/s10434-012-2518-9
- Jäger, Dirk: Predictive immunological markers in oncology / Dirk Jäger, Inka Seil and Niels Halama, 2012. - 3 S.
In: Frontiers in immunology, ISSN 1664-3224. 2(2012), Artikel-ID 86, Seite 1-3
DOI: 10.3389/fimmu.2011.00086
- Halama, Niels: The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic : the way ahead / Niels Halama, Inka Zoernig, Niels Grabe and Dirk Jaeger, 01 Jan 2012. - 5 S.
In: OncoImmunology, ISSN 2162-402X. 1(2012), 1, Seite 62-66
DOI: 10.4161/onci.1.1.18460
- Kahlert, Christoph: Expression analysis of aldehyde deyhdrogenase 1A1 (ALDH1A1) in colon and rectal cancer in association with prognosis and response to chemotherapy / Christoph Kahlert, Eva Gaitzsch, Gunnar Steinert, Carolin Mogler, Esther Herpel, Michael Hoffmeister… , 2012. - 9 S.
In: Annals of surgical oncology, ISSN 1068-9265. 19(2012), 13, Seite 4193-4201
- Podar, Klaus: The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment : therapeutic implications / Klaus Podar, Alexander Zimmerhackl, Mariateresa Fulciniti, Giovanni Tonon, Ursula Hainz, Yu-Tzu Tai,… , 19 September 2011. - 11 S.
In: British journal of haematology, ISSN 1365-2141. 155(2011), 4, Seite 438-448
DOI: 10.1111/j.1365-2141.2011.08864.x
- Halama, Niels: Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy / Niels Halama, Sara Michel, Matthias Kloor, Inka Zoernig, Axel Benner, Anna Spille, Thora Pommerencke… , September 1, 2011. - 8 S.
In: Cancer research, ISSN 1538-7445. 71(2011), 17, Seite 5670-5677
DOI: 10.1158/0008-5472.CAN-11-0268
- Halama, Niels: Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines / Niels Halama, Monika Braun, Christoph Kahlert, Anna Spille, Christian Quack, Nuh Rahbari, Moritz Koc… , February 15, 2011. - 12 S.
In: Clinical cancer research, ISSN 1557-3265. 17(2011), 4, Seite 678-689
DOI: 10.1158/1078-0432.CCR-10-2173
- Halama, Niels: Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines / N. Halama ... C. Kahlert ... N. Rahbari ... J. Weitz; M. Kloor; I. Zoernig; P. Schirmacher; K. Bran… , 2011. - 12 S.
In: Clinical cancer research, ISSN 1078-0432. 17(2011), 4, Seite 678-689
- Lahrmann, Bernd: Automatic tumor-stroma separation in fluorescence TMAs enables the quantitative high-throughput analysis of multiple cancer biomarkers / Lahrmann, B.; Halama, N.; Sinn, H. P.; Schirmacher, P. ... Grabe, N., 2011
In: PLOS ONE, ISSN 1932-6203. 6(2011,12), Artikel-Nr. e28048
DOI: 10.1371/journal.pone.0028048
- Halama, Niels: Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy / Halama, N. ... Kloor, M.; Zoernig, I. ... von Knebel, D. M.; Beckhove, P. ... Schirmacher, P.; Her… , 2011. - 8 S.
In: Cancer research, ISSN 0008-5472. 71(2011), 17, Seite 5670-5677
- Halama, Niels: Quantification of prognostic immune cell markers in colorectal cancer using whole slide imaging tumor maps / Niels Halama, Inka Zoernig, Anna Spille, Sara Michel, Matthias Kloor, Silke Grauling-Halama, Kathi W… , 01 Dec 2010. - 8 S.
In: Analytical and quantitative cytology and histology, ISSN 0884-6812. 32(2010), 6, Seite 333-340
- Gnjatic, Sacha: Seromic profiling of ovarian and pancreatic cancer / Sacha Gnjatic, Erika Ritter, Markus W. Büchler, Nathalia A. Giese, Benedikt Brors, Claudia Frei, Ann… , 2010 Mar 16. - 6 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 107(2010), 11, Seite 5088-5093
DOI: 10.1073/pnas.0914213107
- Lahrmann, Bernd: Robust gridding of TMAs after whole-slide imaging using template matching / Bernd Lahrmann, Niels Halama, Kathi Westphal, Claudia Ernst, Zeinab Elsawaf, Peter Sinn, Franz X. Bo… , 24 November 2010. - 8 S.
In: Cytometry, ISSN 1552-4930. 77A(2010), 12 vom: Nov., Seite 1169-1176
DOI: 10.1002/cyto.a.20949
- Halama, Niels: Kandidatengen- und Mutationsanalyse bei diabetischer Nephropathie / vorgelegt von Niels Halama, 2005. - 79 Bl. : Ill., graph. Darst.
- Halama, Niels: The Kruppel-like zinc-finger gene ZNF236 is alternatively spliced and excluded as susceptibility gene for diabetic nephropathy / Niels Halama, Annette Yard-Breedijk, Irfan Vardarli, Imren Akkoyun, Benito Yard, Bart Janssen, and F… , 2003. - 6 S.
In: Genomics, ISSN 1089-8646. 82(2003), 3, Seite 406-411
DOI: 10.1016/s0888-7543(03)00120-4
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