heiBIB: Okun, Jürgen G.

Okun, Jürgen G. Dr. phil. nat.Universität HeidelbergHeidelberg

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englisch (116)
deutsch (4)

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Publikationen in heiBIB

Saffari, Afshin: Identification of biochemical determinants for diagnosis and prediction of severity in 5q spinal muscular atrophy using 1H-nuclear magnetic resonance metabolic profiling in patient-derived biofluids / Afshin Saffari, Moritz Niesert, Claire Cannet, Astrid Blaschek, Andreas Hahn, Jessika Johannsen, Mus… , 12 November 2024. - 19 S. : Illustrationen
In: International journal of molecular sciences, ISSN 1422-0067. 25(2024), 22, Artikel-ID 12123, Seite 1-19
DOI: 10.3390/ijms252212123
Wu, Yuqin: Phosphoproteomics-directed manipulation reveals SEC22B as a hepatocellular signaling node governing metabolic actions of glucagon / Yuqin Wu, Ashish Foollee, Andrea Y. Chan, Susanne Hille, Jana Hauke, Matthew P. Challis, Jared L. Jo… , 27 September 2024. - 17 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 8390, Seite 1-17
DOI: 10.1038/s41467-024-52703-w
Reischl-Hajiabadi, Anna Theresa: Newborn screening for aromatic l-amino acid decarboxylase deficiency : strategies, results, and implication for prevalence calculations / Anna T. Reischl-Hajiabadi, Jürgen G. Okun, Dirk Kohlmüller, Georgi Manukjan, Sebastian Hegert, Jürge… , 31 January 2024. - 7 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 141(2024), 3, Artikel-ID 108148, Seite 108148-1-108148-7
DOI: 10.1016/j.ymgme.2024.108148
Guivala, Salmina J.: Interactions between the gut microbiome, associated metabolites and the manifestation and progression of heart failure with preserved ejection fraction in ZSF1 rats / Salmina J. Guivala, Konrad A. Bode, Jürgen G. Okun, Ece Kartal, Edzard Schwedhelm, Luca V. Pohl, Sar… , 14 August 2024. - 16 S. : Illustrationen
In: Cardiovascular diabetology, ISSN 1475-2840. 23(2024), Artikel-ID 299, Seite 1-16
DOI: 10.1186/s12933-024-02398-6
Posset, Roland: Severity-adjusted evaluation of liver transplantation on health outcomes in urea cycle disorders / Roland Posset, Sven F. Garbade, Florian Gleich, Svenja Scharre, Jürgen G. Okun, Andrea L. Gropman, S… , April 2024. - 12 S. : Illustrationen
In: Genetics in medicine, ISSN 1530-0366. 26(2024), 4 vom: Apr., Artikel-ID 101039, Seite 1-12
DOI: 10.1016/j.gim.2023.101039
Zaunseder, Elaine: Personalized metabolic whole-body models for newborns and infants predict growth and biomarkers of inherited metabolic diseases / Elaine Zaunseder, Ulrike Mütze, Jürgen G. Okun, Georg F. Hoffmann, Stefan Kölker, Vincent Heuveline,… , 6 August 2024. - 24 S. : Illustrationen
In: Cell metabolism, ISSN 1932-7420. 36(2024), 8 vom: Aug., Seite [1], 1882–1897, e1-e7
DOI: 10.1016/j.cmet.2024.05.006
Seidl, Marie: ASS1 deficiency is associated with impaired neuronal differentiation in zebrafish larvae / Marie J. Seidl, Svenja Scharre, Roland Posset, Ann-Catrin Druck, Friederike Epp, Jürgen G. Okun, Bia… , January 2024. - 11 S. : Illustrationen
In: Molecular genetics and metabolism, ISSN 1096-7206. 141(2024), 1 vom: Jan., Artikel-ID 108097, Seite 1-11
DOI: 10.1016/j.ymgme.2023.108097
Marty-Lombardi, Sebastián: Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain / Sebastián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Anna … , 05 March 2024. - 20 S.
In: Nature metabolism, ISSN 2522-5812. (2024), Seite 1-20
DOI: 10.1038/s42255-024-01001-2
Marty-Lombardi, Sebastián: Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data] / Sebstián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Anna A… . -
Heidelberg: Universität, 2024-01-26. - 1 Online-Ressource (2 Files)
DOI: 10.11588/data/AMDH7G
Janda, Joachim: High throughput newborn screening for Sickle cell disease - application of two-tiered testing with a qPCR-based primary screen / Joachim Janda, Sebastian Hegert, Jessica Bzdok, Rafael Tesorero, Ute Holtkamp, Siegfried Burggraf, E… , 2023. - 7 S. : Illustrationen
In: Klinische Pädiatrie, ISSN 0300-8630. (2023), Seite 1-7
DOI: 10.1055/a-2153-7789
Maier, Esther M.: Collaborative evaluation study on 18 candidate diseases for newborn screening in 1.77 million samples / Esther M. Maier, Ulrike Mütze, Nils Janzen, Ulrike Steuerwald, Uta Nennstiel, Birgit Odenwald, Elfri… , 2023. - 20 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. (2023), Seite 1-20
DOI: 10.1002/jimd.12671
Schnabel-Besson, Elena: Combined newborn screening allows comprehensive identification also of attenuated phenotypes for methylmalonic acidurias and homocystinuria / Elena Schnabel, Stefan Kölker, Florian Gleich, Patrik Feyh, Friederike Hörster, Dorothea Haas, Junmi… , 2023. - 15 S. : Illustrationen
In: Nutrients, ISSN 2072-6643. 15(2023), 15, Artikel-ID 3355, Seite 1-15
DOI: 10.3390/nu15153355
Himmelreich, Nastassja: Complex metabolic disharmony in PMM2-CDG paves the way to new therapeutic approaches / Nastassja Himmelreich, Frauke Kikul, Lucie Zdrazilova, Tomáš Honzik, Andreas Hecker, Gernot Poschet,… , 26 May 2023. - 10 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 139(2023), 3 vom: Juli, Artikel-ID 107610, Seite 1-10
DOI: 10.1016/j.ymgme.2023.107610
Tesorero, Rafael: A high-throughput newborn screening approach for SCID, SMA, and SCD combining multiplex qPCR and tandem mass spectrometry / Rafael Tesorero, Joachim Janda, Friederike Hörster, Patrik Feyh, Ulrike Mütze, Jana Hauke, Kathrin S… , March 10, 2023. - 16 S.
In: PLOS ONE, ISSN 1932-6203. 18(2023), 3 vom: März, Artikel-ID e0283024, Seite 1-16
DOI: 10.1371/journal.pone.0283024
Monostori, Péter: Identification of potential interferents of methylmalonic acid : a previously unrecognized pitfall in clinical diagnostics and newborn screening / Péter Monostori, Markus Godejohann, Joachim Janda, Zsolt Galla, Gábor Rácz, Glynis Klinke, Ildikó Sz… , 2023. - 9 S. : Diagramme
In: Clinical biochemistry, ISSN 1873-2933. 111(2023) vom: Jan., Seite 72-80
DOI: 10.1016/j.clinbiochem.2022.09.010
Cacicedo, Maximiliano L.: mRNA-based therapy proves superior to the standard of care for treating hereditary tyrosinemia 1 in a mouse model / Maximiliano L. Cacicedo, Christine Weinl-Tenbruck, Daniel Frank, Sebastian Wirsching, Beate K. Strau… , September 2022. - 15 S.
In: Molecular therapy, ISSN 2329-0501. 26(2022), Seite 294-308
DOI: 10.1016/j.omtm.2022.07.006
Rossmann, Julia: Validated UPLC-MS/MS method for the analysis of vitamin B6 pyridoxal 5́-phosphate, pyridoxal, pyridoxine, pyridoxamine, and pyridoxic acid in human cerebrospinal fluid / Julia Rossmann, Stine Christ, Sylvia Richter, Sven Friedrich Garbade, Georg Friedrich Hoffmann, Thom… , 14 October 2022. - 9 S.
In: Journal of chromatography, ISSN 1873-376X. 1212(2022), Artikel-ID 123503, Seite 1-9
DOI: 10.1016/j.jchromb.2022.123503
Sekar, Revathi: Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes / Revathi Sekar, Karsten Motzler, Yun Kwon, Aaron Novikoff, Julia Jülg, Bahar Najafi, Surui Wang, Anna… , 14 October 2022. - 28 S.
In: Cell metabolism, ISSN 1932-7420. 34(2022), 11, Seite 1824-1842, e1-e9
DOI: 10.1016/j.cmet.2022.09.022
Götz, Maren: Genotypic and phenotypic spectrum of cytosolic phosphoenolpyruvate carboxykinase deficiency / M. Goetz, J. Schröter, T. Dattner, H. Brennenstuhl, D. Lenza, T. Opladen, F. Hörster, J.G. Okun, G.F… , 19 July 2022. - 8 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 137(2022), 1, Seite 18-25
DOI: 10.1016/j.ymgme.2022.07.007
Sommerburg, Olaf: Final results of the southwest German pilot study on cystic fibrosis newborn screening : evaluation of an IRT/PAP protocol with IRT-dependent safety net / Olaf Sommerburg, Mirjam Stahl, Susanne Hämmerling, Gwendolyn Gramer, Martina U. Muckenthaler, Jürgen… , 2022. - 12 S.
In: Journal of cystic fibrosis, ISSN 1873-5010. 21(2022), 3 vom: Mai, Seite 422-433
DOI: 10.1016/j.jcf.2021.10.007
Sowah, Solomon A.: Calorie restriction improves metabolic state independently of gut microbiome composition : a randomized dietary intervention trial / Solomon A. Sowah, Alessio Milanese, Ruth Schübel, Jakob Wirbel, Ece Kartal, Theron S. Johnson, Frank… , 14 March 2022. - 21 S. : Illustrationen, Diagramme
In: Genome medicine, ISSN 1756-994X. 14(2022), Artikel-ID 30, Seite 1-21
DOI: 10.1186/s13073-022-01030-0
Saffari, Afshin: 1H-NMR-based metabolic profiling identifies non-invasive diagnostic and predictive urinary fingerprints in 5q spinal muscular atrophy / Afshin Saffari, Claire Cannet, Astrid Blaschek, Andreas Hahn, Georg F. Hoffmann, Jessika Johannsen, … , 20 October 2021. - 16 S.
In: Orphanet journal of rare diseases, ISSN 1750-1172. 16(2021), Artikel-ID 441, Seite 1-16
DOI: 10.1186/s13023-021-02075-x
Tunkl, Christine: Corrigendum / [C. Schneider, J.G. Okun, K.V. Schwarz, J. Hauke, M. Zorn, C. Nürnberg, M. Ungerer, P.A. Ringleb and… , 2021. - 2 S.
In: European journal of neurology, ISSN 1468-1331. 28(2021), 8, Seite 2812-2813
DOI: 10.1111/ene.14825
Haas, Dorothea: Differences of phenylalanine concentrations in dried blood spots and in plasma : erythrocytes as a neglected component for this observation / Dorothea Haas, Jana Hauke, Kathrin V. Schwarz, Lucia Consalvi, Friedrich K. Trefz, Nenad Blau, Georg… , 3 October 2021. - 10 S.
In: Metabolites, ISSN 2218-1989. 11(2021), 10, Artikel-ID 680, Seite 1-10
DOI: 10.3390/metabo11100680
Mütze, Ulrike: Health outcomes of infants with vitamin B12 deficiency identified by newborn screening and early treated / Ulrike Mütze, MD, Magdalena Walter, PhD, Mareike Keller, MSc, Gwendolyn Gramer, MD, Sven F. Garbade,… , 11 February 2021. - 7 S.
In: The journal of pediatrics, ISSN 1097-6833. 235(2021) vom: Aug., Seite 42-48
DOI: 10.1016/j.jpeds.2021.02.009
Okun, Jürgen G.: Liver alanine catabolism promotes skeletal muscle atrophy and hyperglycaemia in type 2 diabetes / Jürgen G. Okun, Patricia M. Rusu, Andrea Y. Chan, Yuqin Wu, Yann W. Yap, Thomas Sharkie, Jonas Schum… , 18 March 2021. - 16 S.
In: Nature metabolism, ISSN 2522-5812. 3(2021), 3 vom: März, Seite 394-409
DOI: 10.1038/s42255-021-00369-9
Sommerburg, Olaf: CFTR modulator therapy with lumacaftor/ivacaftor alters plasma concentrations of lipid-soluble vitamins A and E in patients with cystic fibrosis / Olaf Sommerburg, Susanne Hämmerling, S. Philipp Schneider, Jürgen Okun, Claus-Dieter Langhans, Patri… , 19 March 2021. - 15 S.
In: Antioxidants, ISSN 2076-3921. 10(2021), 3, Artikel-ID 483, Seite 1-15
DOI: 10.3390/antiox10030483
Heyse, Miriam: Trimethylamine-N-Oxide levels are similar in asymptomatic vs. symptomatic cerebrovascular atherosclerosis / Miriam Heyse, Christine Schneider, Peter Monostori, Kathrin V. Schwarz, Jana Hauke, Katharina Drüsch… , 19 March 2021. - 6 S.
In: Frontiers in neurology, ISSN 1664-2295. 12(2021) vom: März, Artikel-ID 617944
DOI: 10.3389/fneur.2021.617944
Tunkl, Christine: Trimethylamine-N-oxide is elevated in the acute phase after ischaemic stroke and decreases within the first days / C. Schneider, J.G. Okun, K.V. Schwarz, J. Hauke, M. Zorn, C. Nürnberg, M. Ungerer, P.A. Ringleb and … , 2020. - 8 S.
In: European journal of neurology, ISSN 1468-1331. 27(2020), 8, Seite 1596-1603
DOI: 10.1111/ene.14253
Zielonka, Matthias: From genotype to phenotype : early prediction of disease severity in argininosuccinic aciduria / Matthias Zielonka, Sven F. Garbade, Florian Gleich, Jürgen G. Okun, Sandesh C. S. Nagamani, Andrea L… , 15 January 2020. - 15 S.
In: Human mutation, ISSN 1098-1004. 41(2020), 5, Seite 946-960
DOI: 10.1002/humu.23983
Holle, Johannes: Serum indoxyl sulfate concentrations associate with progression of chronic kidney disease in children / Johannes Holle, Marietta Kirchner, Jürgen Okun, Aysun K. Bayazit, Lukasz Obrycki, Nur Canpolat, Ipek… , October 27, 2020. - 17 S.
In: PLOS ONE, ISSN 1932-6203. 15(2020), 10, Artikel-ID e0240446, Seite 1-17
DOI: 10.1371/journal.pone.0240446
Posset, Roland: Severity-adjusted evaluation of newborn screening on the metabolic disease course in individuals with cytosolic urea cycle disorders / Roland Posset, Stefan Kölker, Florian Gleich, Jürgen G. Okun, Andrea L. Gropman, Sandesh C.S. Nagama… , 7 November 2020. - 8 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 131(2020), 4, Seite 390-397
DOI: 10.1016/j.ymgme.2020.10.013
Brennenstuhl, Heiko: Semi-quantitative detection of a vanillactic acid/vanillylmandelic acid ratio in urine is a reliable diagnostic marker for aromatic L-amino acid decarboxylase deficiency / Heiko Brennenstuhl, Sven F. Garbade, Jürgen G. Okun, Patrik Feyh, Georg F. Hoffmann, Claus-Dieter La… , 07 July 2020. - 8 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 131(2020), 1/2, Seite 163-170
DOI: 10.1016/j.ymgme.2020.07.001
Darwisch, Warda: Cerebellar and hepatic alterations in ACBD5-deficient mice are associated with unexpected, distinct alterations in cellular lipid homeostasis / Warda Darwisch, Marino von Spangenberg, Jana Lehmann, Öznur Singin, Geralt Deubert, Sandra Kühl, Joh… , 26 November 2020. - 19 S.
In: Communications biology, ISSN 2399-3642. 3(2020), Artikel-ID 713, Seite 1-19
DOI: 10.1038/s42003-020-01442-x
Okun, Jürgen G.: Corrigendum to “Molecular regulation of urea cycle function by the liver glucocorticoid receptor” [Mol Metab 4 (10) (2015 Oct) 732-740] / Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Ann… , 5 September 2020. - 1 S.
In: Molecular metabolism, ISSN 2212-8778. 41(2020) vom: Nov., Artikel-ID 101068, Seite 1
DOI: 10.1016/j.molmet.2020.101068
Aidaros, Anas Al: Targeted metabolomic profiling of total fatty acids in human plasma by liquid chromatography-tandem mass spectrometry / Anas Al Aidaros, Charu Sharma, Claus-Dieter Langhans, Jürgen G. Okun, Georg F. Hoffmann, Majed Dasou… , 9 October 2020. - 15 S.
In: Metabolites, ISSN 2218-1989. 10(2020,10) Artikel-Nummer 400, 15 Seiten
DOI: 10.3390/metabo10100400
Probst, Joris: Chronic hyperammonemia causes a hypoglutamatergic and hyperGABAergic metabolic state associated with neurobehavioral abnormalities in zebrafish larvae / Joris Probst, Stefan Kölker, Jürgen G. Okun, Amrish Kumar, Eduard Gursky, Roland Posset, Georg F. Ho… , 25 April 2020. - 12 S.
In: Experimental neurology, ISSN 1090-2430. 331(2020) Artikel-Nummer 113330, 12 Seiten
DOI: 10.1016/j.expneurol.2020.113330
Klinke, Glynis: Targeted cerebrospinal fluid analysis for inborn errors of metabolism on an LC-MS/MS analysis platform / Glynis Klinke, Sylvia Richter, Péter Monostori, Brigitte Schmidt‐Mader, Angels García‐Cazorla, Rafae… , 13 January 2020. - 14 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 43(2020), 4, Seite 712-725
DOI: 10.1002/jimd.12213
Bezerra, Gustavo A.: Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism / Gustavo A. Bezerra, William R. Foster, Henry J. Bailey, Kevin G. Hicks, Sven W. Sauer, Bianca Dimitr… , 10 June 2020. - 14 S.
In: IUCrJ, ISSN 2052-2525. 7(2020), Seite 693-706
DOI: 10.1107/S205225252000696X
Brennenstuhl, Heiko: High throughput newborn screening for aromatic ʟ-amino-acid decarboxylase deficiency by analysis of concentrations of 3-O-methyldopa from dried blood spots / Heiko Brennenstuhl, Dirk Kohlmüller, Gwendolyn Gramer, Sven F. Garbade, Steffen Syrbe, Patrik Feyh, … , 2020. - 9 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 43(2020), 3, Seite 602-610
DOI: 10.1002/jimd.12208
Gramer, Gwendolyn: Newborn screening for vitamin B12 deficiency in Germany : strategies, results, and public health implications / Gwendolyn Gramer, MD, Junmin Fang-Hoffmann, MD, Patrik Feyh, Glynis Klinke, PhD, Peter Monostori, Ph… , 2020. - 12 S.
In: The journal of pediatrics, ISSN 1097-6833. 216(2020) Artikel-Nummer 165-172.e4, 12 Seiten
DOI: 10.1016/j.jpeds.2019.07.052
Holle, Johannes: Indoxyl sulfate associates with cardiovascular phenotype in children with chronic kidney disease / Johannes Holle, Uwe Querfeld, Marietta Kirchner, Alexandros Anninos, Jürgen Okun, Daniela Thurn-Vals… , 19 August 2019. - 12 S.
In: Pediatric nephrology, ISSN 1432-198X. 34(2019), 12, Seite 2571-2582
DOI: 10.1007/s00467-019-04331-6
Sonner, Jana K.: Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology / Jana K. Sonner, Melanie Keil, Maren Falk-Paulsen, Neha Mishra, Ateequr Rehman, Magdalena Kramer, Kat… , 25 October 2019. - 14 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Artikel-Nummer 4877, 14 Seiten
DOI: 10.1038/s41467-019-12776-4
Al-Dirbashi, Osama Y.: Assessment of methylcitrate and methylcitrate to citrate ratio in dried blood spots as biomarkers for inborn errors of propionate metabolism / Osama Y. Al-Dirbashi, Majid Alfadhel, Khalid Al-Thihli, Nahid Al Dhahouri, Claus-Dieter Langhans, Za… , 26 August 2019. - 7 S.
In: Scientific reports, ISSN 2045-2322. 9(2019) Artikel-Nummer 12366, 7 Seiten
DOI: 10.1038/s41598-019-48885-9
Keller, Rebecca: Newborn screening for homocystinurias : recent recommendations versus current practice / Rebecca Keller, Petr Chrastina, Markéta Pavlíková, Sofía Gouveia, Antonia Ribes, Stefan Kölker, Henk… , 11 February 2019. - 121 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 42(2019), 1, Seite 128-139
DOI: 10.1002/jimd.12034
Breuer, Maximilian: QDPR homologues in Danio rerio regulate melanin synthesis, early gliogenesis, and glutamine homeostasis / Maximilian Breuer, Luca Guglielmi, Matthias Zielonka, Verena Hemberger, Stefan Kölker, Jürgen G. Oku… , April 17, 2019. - 19 S.
In: PLOS ONE, ISSN 1932-6203. 14(2019,4) Artikel-Nummer e0215162, 19 Seiten
DOI: 10.1371/journal.pone.0215162
Monostori, Péter: Extended diagnosis of purine and pyrimidine disorders from urine : LC MS/MS assay development and clinical validation / Péter Monostori, Glynis Klinke, Jana Hauke, Sylvia Richter, Jörgen Bierau, Sven F. Garbade, Georg F.… , February 28, 2019. - 17 S.
In: PLOS ONE, ISSN 1932-6203. 14(2019,2) Artikel-Nummer e0212458, 17 Seiten
DOI: 10.1371/journal.pone.0212458
Zielonka, Matthias: Bioenergetic dysfunction in a zebrafish model of acute hyperammonemic decompensation / Matthias Zielonka, Joris Probst, Matthias Carl, Georg Friedrich Hoffmann, Stefan Kölker, Jürgen Günt… , 14 January 2019. - 9 S.
In: Experimental neurology, ISSN 1090-2430. 314(2019), Seite 91-99
DOI: 10.1016/j.expneurol.2019.01.008
Al Dhahouri, Nahid: Quantification of methylcitrate in dried urine spots by liquid chromatography tandem mass spectrometry for the diagnosis of propionic and methylmalonic acidemias / Nahid Al Dhahouri, Claus-Dieter Langhans, Zalikha Al Hammadi, Jürgen G. Okun, Georg F. Hoffmann, Fat… , 11 September 2018. - 5 S.
In: Clinica chimica acta, ISSN 1873-3492. 487(2018), Seite 41-45
DOI: 10.1016/j.cca.2018.09.017
Mendler, Michael: Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes / Michael Mendler, Stefan Kopf, Jan B. Groener, Christin Riedinger, Thomas H. Fleming, Peter P. Nawrot… , 2018. - 8 S.
In: Acta diabetologica, ISSN 1432-5233. 55(2018), 6, Seite 585-592
DOI: 10.1007/s00592-018-1130-2
Dimitrov, Bianca: Cutis laxa, exocrine pancreatic insufficiency and altered cellular metabolomics as additional symptoms in a new patient with ATP6AP1-CDG / Bianca Dimitrov, Nastassja Himmelreich, Agnes L. Hipgrave Ederveen, Christian Lüchtenborg, Jürgen G.… , 2018. - 11 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 123(2018), 3, Seite 364-374
DOI: 10.1016/j.ymgme.2018.01.008
Yu, Qiuliyang: Semisynthetic sensor proteins enable metabolic assays at the point of care / Qiuliyang Yu, Lin Xue, Julien Hiblot, Rudolf Griss, Sebastian Fabritz, Clothilde Roux, Pierre-Alain … , 14 Sep 2018. - 5 S.
In: Science, ISSN 1095-9203. 361(2018), 6407, Seite 1122-1126
DOI: 10.1126/science.aat7992
Iuso, Arcangela: Mutations in PPCS, encoding phosphopantothenoylcysteine synthetase, cause autosomal-recessive dilated cardiomyopathy / Arcangela Iuso, Marit Wiersma, Hans-Joachim Schüller, Ben Pode-Shakked, Dina Marek-Yagel, Mathias Gr… , May 10, 2018. - 13 S.
In: The American journal of human genetics, ISSN 1537-6605. 102(2018), 6, Seite 1018-1030
DOI: 10.1016/j.ajhg.2018.03.022
Riedinger, Christin: High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans / Christin Riedinger, Michael Mendler, Andrea Schlotterer, Thomas Fleming, Jürgen Okun, Hans-Peter Ham… , February 2, 2018. - 16 S.
In: The journal of biological chemistry, ISSN 1083-351X. 293(2018), 13, Seite 4845-4859
Himmelreich, Nastassja: Relationship between genotype, phenylalanine hydroxylase expression and in vitro activity and metabolic phenotype in phenylketonuria / Nastassja Himmelreich, Nan Shen, Jürgen G. Okun, Christian Thiel, Georg F. Hoffmann, Nenad Blau, 23 June 2018. - 10 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 125(2018), 1, Seite 86-95
DOI: 10.1016/j.ymgme.2018.06.011
Senyilmaz-Tiebe, Deniz: Dietary stearic acid regulates mitochondria in vivo in humans / Deniz Senyilmaz-Tiebe, Daniel H. Pfaff, Sam Virtue, Kathrin V. Schwarz, Thomas Fleming, Sandro Altam… , 07 August 2018. - 10 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 3129, 10 Seiten
DOI: 10.1038/s41467-018-05614-6
Gramer, Gwendolyn: High incidence of maternal vitamin B12 deficiency detected by newborn screening : first results from a study for the evaluation of 26 additional target disorders for the German newborn screening panel / Gwendolyn Gramer, Junmin Fang-Hoffmann, Patrik Feyh, Glynis Klinke, Peter Monostori, Jürgen G. Okun,… , 15 June 2018. - 12 S.
In: World journal of pediatrics, ISSN 1867-0687. 14(2018), 5, Seite 470-481
DOI: 10.1007/s12519-018-0159-1
Zielonka, Matthias: Pharmacologic rescue of hyperammonemia-induced toxicity in zebrafish by inhibition of ornithine aminotransferase / Matthias Zielonka, Maximilian Breuer, Jürgen Günther Okun, Matthias Carl, Georg Friedrich Hoffmann, … , September 10, 2018. - 24 S.
In: PLOS ONE, ISSN 1932-6203. 13(2018), 9, Artikel-ID e0203707
DOI: 10.1371/journal.pone.0203707
Meyburg, Jochen: Human heterologous liver cells transiently improve hyperammonemia and ureagenesis in individuals with severe urea cycle disorders / Jochen Meyburg, Thomas Opladen, Ute Spiekerkötter, Andrea Schlune, Jens-Peter Schenk, Jan Schmidt, J… , January 2018. - 10 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 41(2018), 1, Seite 81-90
DOI: 10.1007/s10545-017-0097-4
Bunse, Lukas: Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate / Lukas Bunse, Stefan Pusch, Theresa Bunse, Felix Sahm, Khwab Sanghvi, Mirco Friedrich, Dalia Alansary… , 09 July 2018. - 12 S.
In: Nature medicine, ISSN 1546-170X. 24(2018), Seite 1192-1203
DOI: 10.1038/s41591-018-0095-6
Jabs, Markus: Inhibition of endothelial notch signaling impairs fatty acid transport and leads to metabolic and vascular remodeling of the adult heart / Markus Jabs, Adam J. Rose, Lorenz H. Lehmann, Jacqueline Taylor, Iris Moll, Tjeerd P. Sijmonsma, Ste… , June 12, 2018. - 17 S.
In: Circulation, ISSN 1524-4539. 136(2018), 24, Seite 2592-2608
DOI: 10.1161/CIRCULATIONAHA.117.029733
Komatsuzaki, Shoko: Impairment of astrocytic glutaminolysis in glutaric aciduria type I / Shoko Komatsuzaki, Raga Deepthi Ediga, Jürgen G. Okun, Stefan Kölker, Sven W. Sauer. - 9 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 41(2018), 1, S. 91-99
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Sommerburg, Olaf: Neugeborenenscreening auf Mukoviszidose in Deutschland : Vergleich des neuen Screening-Protokolls mit einem Alternativprotokoll = / Olaf Sommerburg, Mirjam Stahl, Jutta Hammermann, Jürgen G. Okun, Andreas Kulozik, Georg Hoffmann, Ma… , 25. April 2017. - 8 S.
In: Klinische Pädiatrie, ISSN 1439-3824. 229(2017), 2, Seite 59-66
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Leibing, Thomas: Angiocrine Wnt signaling controls liver growth and metabolic maturation in mice / Thomas Leibing, Cyrill Géraud, Iris Augustin, Michael Boutros, Hellmut G. Augustin, Jürgen G. Okun, … , 2018. - 16 S.
In: Hepatology, ISSN 1527-3350. 68(2018), 2, Seite 707-722
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Tagliaferri, Laura: Newborn screening for severe combined immunodeficiency using a novel and simplified method to measure T-cell excision circles (TREC) / Laura Tagliaferri, Joachim B. Kunz, Margit Happich, Susanna Esposito, Thomas Bruckner, Daniel Hübsch… , 2017. - 5 S.
In: Clinical immunology, ISSN 1521-7035. 175(2017), Seite 51-55
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Stremmel, Wolfgang: Blood trimethylamine-N-oxide originates from microbiota mediated breakdown of phosphatidylcholine and absorption from small Intestine / Wolfgang Stremmel, Kathrin V. Schmidt, Vera Schuhmann, Frank Kratzer, Sven F. Garbade, Claus-Dieter … , January 27, 2017. - 9 S.
In: PLOS ONE, ISSN 1932-6203. 12(2017,1) Artikel-Nummer e0170742, 9 Seiten
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Gramer, Gwendolyn: Newborn screening for remethylation disorders and vitamin B<Subscript>12</Subscript> deficiency-evaluation of new strategies in cohorts from Qatar and Germany / Gwendolyn Gramer, Ghassan Abdoh, Tawfeg Ben-Omran, Noora Shahbeck, Rehab Ali, Laila Mahmoud, Junmin … . - 8 S.
In: World journal of pediatrics, ISSN 1867-0687. 13(2017), 2, S. 136-143
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Monostori, Péter: Simultaneous determination of 3-hydroxypropionic acid, methylmalonic acid and methylcitric acid in dried blood spots : Second-tier LC-MS/MS assay for newborn screening of propionic acidemia, methylmalonic acidemias and combined remethylation disorders / Péter Monostori, Glynis Klinke, Sylvia Richter, Ákos Baráth, Ralph Fingerhut, Matthias R. Baumgartne… , September 15, 2017. - 16 S.
In: PLOS ONE, ISSN 1932-6203. 12(2017,9) Artikel-Nummer e0184897, 16 Seiten
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Thewes, Verena: The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer / V. Thewes, R. Simon, M. Hlevnjak, M. Schlotter, P. Schroeter, K. Schmidt, Y. Wu, T. Anzeneder, W. Wa… , 20 March 2017. - 11 S.
In: Oncogene, ISSN 1476-5594. 36(2017), 29, Seite 4124-4134
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Weidler, Sophia: A product of immunoreactive trypsinogen and pancreatitis-associated protein as second-tier strategy in cystic fibrosis newborn screening / Sophia Weidler, Konrad H. Stopsack, Jutta Hammermann, Olaf Sommerburg, Marcus A. Mall, Georg F. Hoff… , 22 July 2016. - 7 S.
In: Journal of cystic fibrosis, ISSN 1873-5010. 15(2016), 6, Seite 752-758
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Frongia, Giovanni: Significance of the extent of intestinal resection on the outcome of a short-bowel syndrome in a porcine model / Giovanni Frongia, MD, Arash Nickkholgh, MD, Mohammad Reza Hafezi M, MD, Jalal Arvin, MD, Arash Saffa… , 2016. - 9 S.
In: Journal of investigative surgery, ISSN 1521-0553. 29(2016), 1, Seite 57-65
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Shen, Nan: Co-expression of phenylalanine hydroxylase variants and effects of interallelic complementation on in vitro enzyme activity and genotype-phenotype correlation / Nan Shen, Caroline Heintz, Christian Thiel, Jürgen G. Okun, Georg F. Hoffmann, Nenad Blau, 12 January 2016. - 8 S.
In: Molecular genetics and metabolism, ISSN 1096-7206. 117(2016), 3, Seite 328-335
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Fuhrmeister, Jessica: Fasting‐induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health / Jessica Fuhrmeister, Annika Zota, Tjeerd P. Sijmonsma, Oksana Seibert, Şahika Cıngır, Kathrin Schmid… , 3 May 2016. - 16 S.
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Bartosova, Maria: Increased storage and secretion of phosphatidylcholines by senescent human peritoneal mesothelial cells / Maria Bartosova, Andras Rudolf, Sebastian Pichl, Kathrin Schmidt, Jürgen G. Okun, Beate K. Straub, R… , August 2016. - 8 S.
In: Clinical and experimental nephrology, ISSN 1437-7799. 20(2016), 4, Seite 544-551
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Boy, Nikolas: Proposed recommendations for diagnosing and managing individuals with glutaric aciduria type I : second revision / Nikolas Boy, Chris Mühlhausen, Esther M. Maier, Jana Heringer, Birgit Assmann, Peter Burgard, Marjor… , 2017. - 27 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 40(2017), 1, Seite 75-101
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Staufner, Christian: Genetic cause and prevalence of hydroxyprolinemia / Christian Staufner, Tobias B. Haack, Patrik Feyh, Gwendolyn Gramer, Deepthi Ediga Raga, Caterina Ter… , 2 May 2016. - 8 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 39(2016), 5, Seite 625-632
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Balß, Jörg: Pretreatment d -2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia / J. Balss, C. Thiede, T. Bochtler, J.G. Okun, M. Saadati, A. Benner, S. Pusch, G. Ehninger, M. Schaic… , 2016. - 7 S.
In: Leukemia, ISSN 1476-5551. 30(2016), 4, Seite 782-788
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Pathil-Warth, Anita: Ursodeoxycholyl lysophosphatidylethanolamide modifies aberrant lipid profiles in NAFLD / Anita Pathil, Gerhard Liebisch, Jürgen G. Okun, Walee Chamulitrat, Gerd Schmitz and Wolfgang Stremme… , 24 June 2015. - 7 S.
In: European journal of clinical investigation, ISSN 1365-2362. 45(2015), 9, Seite 925-931
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Okun, Jürgen G.: Molecular regulation of urea cycle function by the liver glucocorticoid receptor / Jürgen G. Okun, Sean Conway, Kathrin V. Schmidt, Jonas Schumacher, Xiaoyue Wang, Roldan de Guia, Ann… , 30 July 2015. - 9 S.
In: Molecular metabolism, ISSN 2212-8778. 4(2015), 10, Seite 732-740
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Kunz, Joachim: Significant prevalence of sickle cell disease in Southwest Germany : results from a birth cohort study indicate the necessity for newborn screening / Joachim B. Kunz, Saida Awad, Margit Happich, Lena Muckenthaler, Martin Lindner, Gwendolyn Gramer, Jü… , 2016. - 6 S.
In: Annals of hematology, ISSN 1432-0584. 95(2016), 3, Seite 397-402
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Sauer, Sven: Multifactorial modulation of susceptibility to l-lysine in an animal model of glutaric aciduria type I / Sven W. Sauer, Silvana Opp, Shoko Komatsuzaki, Anna-Eva Blank, Michel Mittelbronn, Peter Burgard, D.… . - 10 S.
In: Biochimica et biophysica acta, ISSN 1879-260X. 1852(2015), 5, S. 768-777
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Posset, Roland: Understanding cerebral L-lysine metabolism : the role of L-pipecolate metabolism in Gcdh-deficient mice as a model for glutaric aciduria type I / Roland Posset, Silvana Opp, Eduard A. Struys, Alfred Völkl, Heribert Mohr, Georg F. Hoffmann, Stefan… , 2015. - 9 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 38(2015), 2, Seite 265-272
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Ruppert, Thomas: Molecular and biochemical alterations in tubular epithelial cells of patients with isolated methylmalonic aciduria / T. Ruppert, A. Schumann, H.J. Gröne, J.G. Okun, S. Kölker, M.A. Morath and S.W. Sauer. - 11 S.
In: Human molecular genetics, ISSN 1460-2083. 24(2015), 24, S. 7049-7059
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Tuncel, Ali Tunç: Maleic acid - but not structurally related methylmalonic acid : interrupts energy metabolism by impaired calcium homeostasis / Ali Tunç Tuncel ; Thorsten Ruppert ; Bei-Tzu Wang ; Jürgen Günther Okun ; Stefan Kölker ; Marina Ale…
In: PLOS ONE, ISSN 1932-6203. 10(2015,6) Artikel-Nr. e0128770, 19 S.
DOI: 10.1371/journal.pone.0128770
Dietrich, Sascha: High pre-transplant serum nitrate levels predict risk of acute steroid-refractory graft-versus-host disease in the absence of statin therapy / Sascha Dietrich, Jürgen G. Okun, Kathrin Schmidt, Christine S. Falk, Andreas H. Wagner, Suzan Karamu… , March 2014. - 7 S.
In: Haematologica, ISSN 1592-8721. 99(2014), 3, Seite 541-547
DOI: 10.3324/haematol.2013.090209
Vanlander, Arnaud Vincent: Possible pathogenic mechanism of propofol infusion syndrome Involves coenzyme q / Arnaud Vincent Vanlander, M.D., Juergen Guenther Okun, Ph.D., Annick de Jaeger, M.D., Joél Smet, B.A… , 2015. - 10 S.
In: Anesthesiology, ISSN 1528-1175. 122(2015), 2, Seite 343-352
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Rahman, Mahbubur: The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages / Mahbubur Rahman, Sajjad Muhammad, Mahtab A. Khan, Hui Chen, Dirk A. Ridder, Helge Müller-Fielitz, Ba…
In: Nature Communications, ISSN 2041-1723. 5(2014) Artikel-Nummer 3944, 11 Seiten
DOI: 10.1038/ncomms4944
Keil, Melanie: Dietary tryptophan is required for CNS infiltration of encephalitogenic T cells / Melanie Keil, Maren Paulsen, Jana Sonner, Florian Wanke, Iris Oezen, Theresa Schumacher, Jürgen G. O… , 15 October 2014. - 1 S.
In: Journal of neuroimmunology, ISSN 1872-8421. 275(2014,1/2) Artikel-Nr. 259, 1 Seite
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Haas, Dorothea: Diagnosis and therapeutic monitoring of inborn errors of creatine metabolism and transport using liquid chromatography-tandem mass spectrometry in urine, plasma and CSF / Dorothea Haas, Hongying Gan-Schreier, Claus-Dieter Langhans, Alexandros Anninos, Gisela Haege, Peter… , 15 March 2014. - 7 S.
In: Gene, ISSN 1879-0038. 538(2014), 1, Seite 188-194
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Bunse, Theresa: A vaccine targeting mutant IDH1 induces antitumour immunity / Theresa Schumacher, Lukas Bunse, Stefan Pusch, Felix Sahm, Benedikt Wiestler, Jasmin Quandt, Oliver … , 2014. - 17 S.
In: Nature, ISSN 1476-4687. 512(2014,7514) S. 324-327, [13] S.
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Tönjes, Martje: BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 / Martje Tönjes, Sebastian Barbus, Yoon Jung Park, Wei Wang, Magdalena Schlotter, Anders M. Lindroth, … , 23 June 2013. - 8 S.
In: Nature medicine, ISSN 1546-170X. 19(2013), 7, Seite 901-908
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Kölker, Stefan: Current concepts in organic acidurias : understanding intra- and extracerebral disease manifestation / Stefan Kölker, Peter Burgard, Sven W. Sauer, Jürgen G. Okun, 20 March 2013. - 10 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 36(2013), 4, Seite 635-644
DOI: 10.1007/s10545-013-9600-8
Vanlander, Arnaud Vincent: Inborn oxidative phosphorylation defect as risk factor for propofol infusion syndrome / A.V. Vanlander, P.G. Jorens, J. Smet, B. De Paepe, W. Verbrugghe, G.G. Van Den Eynden, F. Meire, P. … . - 6 S.
In: Acta anaesthesiologica Scandinavica, ISSN 1399-6576. 56(2012), 4, S. 520-525
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Balß, Jörg: Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate / Jörg Balss, Stefan Pusch, Ann-Christin Beck, Christel Herold-Mende, Alwin Krämer, Christian Thiede, … , 2 November 2012. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 6, Seite 883-891
DOI: 10.1007/s00401-012-1060-y
Haas, Dorothea: Differential diagnosis in patients with suspected bile acid synthesis defects / Dorothea Haas, Hongying Gan-Schreier, Claus-Dieter Langhans, Tilman Rohrer, Guido Engelmann, Maura H… , March 14, 2012. - 10 S.
In: World journal of gastroenterology, ISSN 2219-2840. 18(2012), 10, Seite 1067-1076
DOI: 10.3748/wjg.v18.i10.1067
Danhauser, Katharina: DHTKD1 mutations cause 2-Aminoadipic and 2-Oxoadipic aciduria / Katharina Danhauser, Sven W. Sauer, Tobias B. Haack, Thomas Wieland, Christian Staufner, Elisabeth G… , November 8, 2012. - 6 S.
In: The American journal of human genetics, ISSN 1537-6605. 91(2012), 6, Seite 1082-1087
DOI: 10.1016/j.ajhg.2012.10.006
Capper, David: 2‐Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size / Capper David, Simon Matthias, Langhans Claus‐Dieter, Okun Jürgen G., Tonn Jörg C., Weller Michael, D… , 1 August 2012. - 3 S.
In: International journal of cancer, ISSN 1097-0215. 131(2012), 3, Seite 766-768
DOI: 10.1002/ijc.26425
Schmelzer, Constance: Ubiquinol-induced gene expression signatures are translated into altered parameters of erythropoiesis and reduced low density lipoprotein cholesterol levels in humans / Constance Schmelzer, Petra Niklowitz, Jürgen G. Okun, Dorothea Haas, Thomas Menke, Frank Döring, 28 January 2011. - 7 S.
In: IUBMB life, ISSN 1521-6551. 63(2011), 1, Seite 42-48
DOI: 10.1002/iub.413
Sauer, Sven: Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type I / Sven W. Sauer, Silvana Opp, Georg F. Hoffmann, David M. Koeller, Jürgen G. Okun and Stefan Kölker, 2011. - 14 S.
In: Brain, ISSN 1460-2156. 134(2011), 1, Seite 157-170
DOI: 10.1093/brain/awq269
Sauer, Sven: Severe dysfunction of respiratory chain and cholesterol metabolism in Atp7b−/− mice as a model for Wilson disease / Sven W. Sauer, Uta Merle, Silvana Opp, Dorothea Haas, Georg F. Hoffmann, Wolfgang Stremmel, Jürgen G… , 2 September 2011. - 9 S.
In: Biochimica et biophysica acta, ISSN 1879-260X. 1812(2011), 12, Seite 1607-1615
DOI: 10.1016/j.bbadis.2011.08.011
Kölker, Stefan: Glutarazidurie Typ I : Von der interdisziplinären Forschung zur strukturierten Patientenversorgung / S. Kölker, S.W. Sauer, J.G. Okun, P. Burgard, G.F. Hoffmann, 31 August 2011. - 6 S.
In: Monatsschrift Kinderheilkunde, ISSN 1433-0474. 159(2011), 9, Seite 842-847
DOI: 10.1007/s00112-011-2443-1
Sahm, Felix: Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry / Felix Sahm, David Capper, Stefan Pusch, Jörg Balss, Arend Koch, Claus‐Dieter Langhans, Jürgen G. Oku… . - 6 S.
In: Brain pathology, ISSN 1750-3639. 22(2012), 1, S. 26-31
DOI: 10.1111/j.1750-3639.2011.00506.x
Strathmann, Julia: Xanthohumol-induced transient superoxide anion radical formation triggers cancer cells into apoptosis via a mitochondria-mediated mechanism / Julia Strathmann, Karin Klimo, Sven W. Sauer, Jürgen G. Okun, Jochen H.M. Prehn, and Clarissa Gerhäu… , 24 March 2010. - 13 S.
In: The FASEB journal, ISSN 1530-6860. 24(2010), 8 vom: Aug., Seite 2938-2950
DOI: 10.1096/fj.10-155846
Sauer, Sven: Erratum to: Long-term exposure of human proximal tubule cells to hydroxycobalamin[c-lactam] as a possible model to study renal disease in methylmalonic acidurias / S.W. Sauer, S. Opp, A. Haarmann, J.G. Okun, S. Kölker, M.A. Morath, 11 February 2010. - 1 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 33(2010), 1, Seite 93
DOI: 10.1007/s10545-010-9064-z
Sellner, Leopold: Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations / Leopold Sellner, David Capper, Jochen Meyer, Claus-Dieter Langhans, Christine-Maria Hartog, Heike Pf… , 26 July 2010. - 3 S.
In: European journal of haematology, ISSN 1600-0609. 85(2010), 5, Seite 457-459
DOI: 10.1111/j.1600-0609.2010.01505.x
Opladen, Thomas: Phenylalanine loading in pediatric patients with dopa-responsive dystonia : revised test protocol and pediatric cutoff values / Thomas Opladen, Jürgen G. Okun, Peter Burgard, Nenad Blau, Georg F. Hoffmann, 29 July 2010. - 7 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 33(2010), 6 vom: Dez., Seite 697-703
DOI: 10.1007/s10545-010-9164-9
Schmelzer, Constance: The reduced form of coenzyme Q10 mediates distinct effects on cholesterol metabolism at the transcriptional and metabolite level in SAMP1 mice / Constance Schmelzer, Jürgen G. Okun, Dorothea Haas, Keiichi Higuchi, Jinko Sawashita, Masayuki Mori … , 17 November 2010. - 7 S.
In: IUBMB life, ISSN 1521-6551. 62(2010), 11 vom: Nov., Seite 812-818
DOI: 10.1002/iub.388
Rauschenberger, Katharina: A non-enzymatic function of 17β-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival / Katharina Rauschenberger, Katja Schöler, Jörn Oliver Sass, Sven Sauer, Zdenka Djuric, Cordula Rumig,… , 4 February 2010. - 12 S.
In: EMBO molecular medicine, ISSN 1757-4684. 2(2010), 2 vom: Feb., Seite 51-62
DOI: 10.1002/emmm.200900055
Kamiński, Marcin: Mitochondrial reactive oxygen species control T cell activation by regulating IL-2 and IL-4 expression : mechanism of ciprofloxacin-mediated immunosuppression / Marcin M. Kamiński, Sven W. Sauer, Claus-Detlev Klemke, Dorothee Süss, Jürgen G. Okun, Peter H. Kram… , May 01 2010. - 15 S.
In: The journal of immunology, ISSN 1550-6606. 184(2010), 9 vom: Mai, Seite 4827-4841
DOI: 10.4049/jimmunol.0901662
Sauer, Sven: Glutaric aciduria type I and methylmalonic aciduria : simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus / Sven W. Sauer, Silvana Opp, Anne Mahringer, Marcin M. Kamiński, Christian Thiel, Jürgen G. Okun, Ger… , 2010. - 9 S.
In: Biochimica et biophysica acta, ISSN 1879-260X. 1802(2010), 6, Seite 552-560
DOI: 10.1016/j.bbadis.2010.03.003
Sauer, Sven: Long-term exposure of human proximal tubule cells to hydroxycobalamin[c-lactam] as a possible model to study renal disease in methylmalonic acidurias / S.W. Sauer, S. Opp, A. Haarmann, J.G. Okun, S. Kölker, M.A. Morath, 10 October 2009. - 8 S.
In: Journal of inherited metabolic disease, ISSN 1573-2665. 32(2009), 6, Seite 720-727
DOI: 10.1007/s10545-009-1197-6
Sauer, Sven: Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited ﬂux across the blood–brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deﬁciency / Sven W. Sauer, Jürgen G. Okun, Gert Fricker, Anne Mahringer, Ines Müller, Linda R. Crnic, Chris Mühl… , 2006. - 12 S.
In: Journal of neurochemistry, ISSN 1471-4159. 97(2006), 3, Seite 899-910
DOI: 10.1111/j.1471-4159.2006.03813.x
Okun, Jürgen G.: Bioenergetische Modelle zur Untersuchung der pathophysiologischen Bedeutung des mitochondrialen Energiestoffwechsels bei angeborenen Stoffwechselerkrankungen / vorgelegt von Jürgen G. Okun, 2005 [ersch.] 2006. - Getr. Zählung : Ill., graph. Darst.
Kölker, Stefan: Chronic treatment with glutaric acid induces partial tolerance to excitotoxicity in neuronal cultures from chick embryo telencephalons / Stefan Kölker, Jürgen G. Okun, Barbara Ahlemeyer, Angela T.S. Wyse, Friederike Hörster, Moacir Wajne… , 05 April 2002. - 7 S.
In: Journal of neuroscience research, ISSN 1097-4547. 68(2002), 4, Seite 424-431
DOI: 10.1002/jnr.10189
Okun, Jürgen G.: Neurodegeneration in methylmalonic aciduria involves inhibition of complex II and the tricarboxylic acid cycle, and synergistically acting excitotoxicity / Jürgen G. Okun, Friederike Hörster, Lilla M. Farkas, Patrik Feyh, Angela Hinz, Sven Sauer, Georg F. … , 14 February 2002. - 7 S.
In: The journal of biological chemistry, ISSN 1083-351X. 277(2002), 17, Seite 14674-14680
DOI: 10.1074/jbc.M200997200
Okun, Jürgen G.: A method for quantitative acylcarnitine profiling in human skin fibroblasts using unlabelled palmitic acid : diagnosis of fatty acid oxidation disorders and differentiation between biochemical phenotypes of MCAD deficiency / Jürgen G Okun, Stefan Kölker, Andreas Schulze, Dirk Kohlmüller, Katharina Olgemöller, Martin Lindner… , 19 September 2002. - 8 S.
In: Biochimica et biophysica acta, ISSN 1879-2618. 1584(2002), 2, Seite 91-98
DOI: 10.1016/S1388-1981(02)00296-2
Kölker, Stefan: Ca 2+ and Na + dependence of 3-hydroxyglutarate-induced excitotoxicity in primary neuronal cultures from chick embryo telencephalons / Stefan Kölker, Georg Köhr, Barbara Ahlemeyer, Jürgen G. Okun, Verena Pawlak, Friederike Hörster, Ert… , 2002. - 8 S.
In: Pediatric research, ISSN 1530-0447. 52(2002), 2, Seite 199-206
DOI: 10.1203/00006450-200208000-00011
Kölker, Stefan: NMDA receptor activation and respiratory chain complex V inhibition contribute to neurodegeneration in d-2-hydroxyglutaric aciduria / Stefan Kölker, Verena Pawlak, Barbara Ahlemeyer, Jürgen G. Okun, Friederike Hörster, Ertan Mayatepek… , 11 July 2002. - 8 S.
In: European journal of neuroscience, ISSN 1460-9568. 16(2002), 1, Seite 21-28
DOI: 10.1046/j.1460-9568.2002.02055.x
Okun, Jürgen G.: Isolierung und Charakterisierung von Komplex 1 (NADH:Ubichinon Oxidoreduktase) aus Rinderherzmitochondrien / von Jürgen G. Okun, 1999. - 88 Bl. : graph. Darst.

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