
Klein, Christian D. Dr. rer. nat.; Prof.Universität HeidelbergHeidelberg
Publikationsliste einschränken
Publikationsjahre
Publikationstypen
Sprache
Co-Autoren (Uni Heidelberg)
- Marschner, Aline (4)
- Sundermann, Tom R. (4)
- Scholz, Therese (3)
- Boldescu, Veaceslav (3)
- Dražić, Tonko (3)
- Rominger, Frank (2)
- Mendgen, Thomas (2)
- Heyl, Carina (2)
- Altmeyer, Markus (2)
- Özata, Başak (2)
- Jöst, Christian (2)
- Weigel, Lena (2)
- Helmchen, Günter (2)
- Richter, Michael (2)
- Hinkes, Stefan (2)
- Brügger, Britta (2)
- Vechi, Sergio (2)
- Behrouz, Somayeh (2)
- Pham, Truc Lam (2)
- Lang, Johannes (2)
- Werner, Marius (2)
- Heim, Thomas (2)
- Brinkhofer, Julian (2)
- Huber, Jonas (2)
- Thomas, Franziska (2)
- Fischl, Wolfgang (1)
- Bading, Hilmar (1)
- Mauceri, Daniela (1)
- Morgen, Michael (1)
- Kumar, Anil (1)
- Schreier, Verena Natalie (1)
- Seehafer, Kai (1)
- Hemstedt, Thekla Joana (1)
- (weitere Einträge vorhanden...)
Co-Autoren (extern)
- Mahawaththa, Mithun C. (1)
- Poręba, Marcin (1)
- Weng, Zhibing (1)
- Dokla, Eman M. E. (1)
- Shalaby, Menna-Allah W. (1)
- Seleem, Mohamed N. (1)
- Nasr, Maha (1)
- Milik, Sandra N. (1)
- Li, Daoyi (1)
- El-Baz, Karim (1)
- Al-Karaki, Rawan (1)
- Abutaleb, Nader S. (1)
- Chen, Wan-Na (1)
- Pilla, Kala Bharath (1)
- Otting, Gottfried (1)
- Graham, Bim (1)
- Zhang, Linlin (1)
- Lei, Jian (1)
- Hilgenfeld, Rolf (1)
- Hansen, Guido (1)
- Marzo, Vincenzo Di (1)
- Mahmoud, Amr H. (1)
- Abouzid, Khaled M. (1)
- Zlotos, Darius P. (1)
- Roux, Lionel (1)
- Niessing, Dierk (1)
- Janowski, Robert (1)
- Rabbito, Alessandro (1)
- Ligresti, Alessia (1)
- Di Marzo, Vincenzo (1)
- Abouzid, Khaled A. (1)
- Hacker, Christina N. (1)
- Gottscheber, Nicole (1)
- (weitere Einträge vorhanden...)
Publikationen in heiBIB 
- Lang, Johannes: Antiviral drug discovery with an optimized biochemical dengue protease assay : Improved predictive power for antiviral efficacy / Johannes Lang, Sudip Kumar Dutta, Mila M. Leuthold, Lisa Reichert, Nikos Kühl, Byron Martina, Christ… , February 2025. - 12 S. : Illustrationen
In: Antiviral research, ISSN 1872-9096. 234(2025) vom: Feb., Artikel-ID 106053, Seite 1-12
DOI: 10.1016/j.antiviral.2024.106053
- Werner, Marius: Peptide boronic acids by late-stage hydroboration on the solid phase [research data] / Marius Werner, Julian Brinkhofer, Leon Hammermüller, Thomas Heim, Truc Lam Pham, Jonas Huber, Christ… . -
Heidelberg: Universität, 2025-01-17. - 1 Online Ressource (5 Files)
DOI: 10.11588/data/G9NMGA
- Behnam, Mira A. M.: Alternate recognition by dengue protease : proteolytic and binding assays provide functional evidence beyond an induced-fit / Mira A.M. Behnam, Christian D. Klein, December 2024. - 13 S. : Illustrationen
In: Biochimie. 227(2024) vom: Dez., Seite 15-27
DOI: 10.1016/j.biochi.2024.06.002
- Werner, Marius: Peptide boronic acids by late-stage hydroboration on the solid phase / Marius Werner, Julian Brinkhofer, Leon Hammermüller, Thomas Heim, Truc Lam Pham, Jonas Huber, Christ… , May 2024. - 11 S. : Illustrationen
In: Advanced science, ISSN 2198-3844. 11(2024), 28 vom: Mai, Artikel-ID 2400640, Seite 1-11
DOI: 10.1002/advs.202400640
- Behnam, Mira A. M.: 2,2′-Bithiophene as sensor tag for ligand-protein binding assays based on Förster resonance energy transfer / Mira A.M. Behnam, Thomas Basché, Christian D.P. Klein, 1 December 2023. - 7 S.
In: Analytical biochemistry, ISSN 1096-0309. 682(2023), Artikel-ID 115335, Seite 1-7
DOI: 10.1016/j.ab.2023.115335
- Behrouz, Somayeh: N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors / Somayeh Behrouz, Nikos Kühl, Christian D. Klein, 7 March 2023. - 14 S.
In: European journal of medicinal chemistry, ISSN 1768-3254. 251(2023) vom: März, Artikel-ID 115227, Seite 1-14
DOI: 10.1016/j.ejmech.2023.115227
- Kühl, Nikos: Discovery of potent benzoxaborole inhibitors against SARS-CoV-2 main and dengue virus proteases / Nikos Kühl, Johannes Lang, Mila M. Leuthold, Christian D. Klein, 11 July 2022. - 14 S.
In: European journal of medicinal chemistry, ISSN 1768-3254. 240(2022), Artikel-ID 114585, Seite 1-14
DOI: 10.1016/j.ejmech.2022.114585
- Milik, Sandra: Insights into the design of inhibitors of the EGFR family with anticancer activity overcoming resistance : a case of optimizing thieno[2,3-d]pyrimidine-based EGFR inhibitors / Sandra N. Milik, Amal Kamal Abdel-Aziz, Morad M. El-Hendawy, Riham I. El-Gogary, Mona Kamal Saadeldi… , 2 March 2022. - 13 S.
In: Journal of molecular structure, ISSN 1872-8014. 1259(2022), Artikel-ID 132724, Seite 1-13
DOI: 10.1016/j.molstruc.2022.132724
- Behnam, Mira A. M.: On track to tackle dengue : History and future of NS4B ligands / Mira A.M. Behnam, Christian D. Klein, 8 December 2021. - 3 S.
In: Cell host and microbe, ISSN 1934-6069. 29(2021), 12, Seite 1735-1737
DOI: 10.1016/j.chom.2021.11.010
- Behrouz, Somayeh: A facile approach towards amidinophenylalanine derivatives as building blocks for the synthesis of non-natural peptides and peptidomimetics / Somayeh Behrouz, Nikos Kühl, Christian D. Klein, 22 August 2021. - 7 S.
In: Tetrahedron letters, ISSN 1873-3581. 81(2021), Artikel-ID 153342, Seite 1-7
DOI: 10.1016/j.tetlet.2021.153342
- Dražić, Tonko: The spectrum between substrates and inhibitors : Pinpointing the binding mode of dengue protease ligands with modulated basicity and hydrophobicity / Tonko Dražić, Nikos Kühl, Nicole Gottscheber, Christina N. Hacker, Christian D. Klein, 17 September 2021. - 16 S.
In: Bioorganic & medicinal chemistry, ISSN 1464-3391. 48(2021), Artikel-ID 116412, Seite 1-16
DOI: 10.1016/j.bmc.2021.116412
- Behnam, Mira A. M.: Inhibitor potency and assay conditions : a case study on SARS-CoV-2 main protease / Mira A.M. Behnam and Christian D. Klein, September 2, 2021. - 2 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 118(2021), 36, Artikel-ID e2106095118, Seite 1-2
DOI: 10.1073/pnas.2106095118
- Kühl, Nikos: Beyond basicity : discovery of nonbasic DENV-2 protease inhibitors with potent activity in cell culture / Nikos Kühl, Mila M. Leuthold, Mira A.M. Behnam, and Christian D. Klein, April 14, 2021. - 21 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 64(2021), 8, Seite 4567-4587
DOI: 10.1021/acs.jmedchem.0c02042
- Behnam, Mira A. M.: Conformational selection in the flaviviral NS2B-NS3 protease / Mira A.M. Behnam, Christian D.P. Klein, 23 April 2020. - 9 S.
In: Biochimie. 174(2020), Seite 117-125
DOI: 10.1016/j.biochi.2020.04.014
- Hinkes, Stefan: Diversity-oriented synthesis of peptide-boronic acids by a versatile building-block approach / Stefan P.A. Hinkes, Severin Kämmerer, and Christian D.P. Klein, 21 Aug 2020. - 6 S.
In: Chemical science, ISSN 2041-6539. 11(2020), 36, Seite 9898-9903
DOI: 10.1039/D0SC03999C
- Oosten, Luuk N. van: Machine learning in mass spectrometry : A MALDI-TOF MS approach to phenotypic antibacterial screening / Luuk N. van Oosten, Christian D. Klein, March 19, 2020. - 8 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 63(2020), 16, Seite 8849-8856
DOI: 10.1021/acs.jmedchem.0c00040
- Kühl, Nikos: A new class of Dengue and west Nile virus protease inhibitors with submicromolar activity in reporter gene DENV-2 protease and viral replication assays / Nikos Kühl, Dominik Graf, Josephine Bock, Mira A. M. Behnam, Mila-Mareen Leuthold, and Christian D. … , July 1, 2020. - 9 S. : Illustrationen
In: Journal of medicinal chemistry, ISSN 1520-4804. 63(2020), 15, Seite 8179-8197
DOI: 10.1021/acs.jmedchem.0c00413
- Mauceri, Daniela: Nasally delivered VEGFD mimetics mitigate stroke-induced dendrite loss and brain damage / Daniela Mauceri, Bettina Buchthal, Thekla J. Hemstedt, Ursula Weiss, Christian D. Klein, and Hilmar … , March 30, 2020. - 8 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 117(2020), 15, Seite 8616-8623
DOI: 10.1073/pnas.2001563117
- Dokla, Eman M. E.: Development of benzimidazole-based derivatives as antimicrobial agents and their synergistic effect with colistin against gram-negative bacteria / Eman M. E. Dokla, Nader S. Abutaleb, Sandra N. Milik, Daoyi Li, Karim El-Baz, Menna-Allah W. Shalaby… , [15 January 2020]. - 9 S. : Diagramme
In: European journal of medicinal chemistry, ISSN 1768-3254. 186(2020) Artikel-Nummer 111850, Seite 1-9
DOI: 10.1016/j.ejmech.2019.111850
- Dražić, Tonko: Peptide-β-lactam inhibitors of Dengue and West Nile virus NS2B-NS3 protease display two distinct binding modes / Tonko Dražić, Sara Kopf, James Corridan, Mila M. Leuthold, Branimir Bertoša, and Christian D. Klein, 2020. - 17 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 63(2020), 1, Seite 140-156
DOI: 10.1021/acs.jmedchem.9b00759
- Richter, Michael: Prodrug activation by a viral protease : evaluating combretastatin peptide hybrids to selectively target infected cells / Michael Richter, Mila M. Leuthold, Dominik Graf, Ralf Bartenschlager, Christian D. Klein, July 18, 2019. - 7 S.
In: ACS medicinal chemistry letters, ISSN 1948-5875. 10(2019), 8, Seite 1115-1121
DOI: 10.1021/acsmedchemlett.9b00058
- Hinkes, Stefan: Virtues of volatility : a facile transesterification approach to boronic acids / Stefan P.A. Hinkes, Christian D.P. Klein, April 23, 2019. - 5 S.
In: Organic letters, ISSN 1523-7052. 21(2019), 9, Seite 3048-3052
DOI: 10.1021/acs.orglett.9b00584
- Nitsche, Christoph: De Novo discovery of nonstandard macrocyclic peptides as noncompetitive inhibitors of the Zika Virus NS2B-NS3 protease / Christoph Nitsche, Toby Passioura, Paul Varava, Mithun C. Mahawaththa, Mila M. Leuthold, Christian D… , 4 January 2019. - 7 S.
In: ACS medicinal chemistry letters, ISSN 1948-5875. 10(2019), 2, Seite 168-174
DOI: 10.1021/acsmedchemlett.8b00535
- Richter, Michael: Synthesis, biological evaluation, and molecular docking of combretastatin and colchicine derivatives and their hCE1-activated prodrugs as antiviral agents / Michael Richter, Veaceslav Boldescu, Dominik Graf, Felix Streicher, Anatoli Dimoglo, Ralf Bartenschl… , 03 January 2019. - 15 S.
In: ChemMedChem, ISSN 1860-7187. 14(2019), 4, Seite 469-483
DOI: 10.1002/cmdc.201800641
- Sundermann, Tom R.: Synthesis and structure-activity relationships of small-molecular di-basic esters, amides and carbamates as flaviviral protease inhibitors / Tom R. Sundermann, Clarissa V. Benzin, Tonko Dražić, Christian D. Klein, 8 May 2019. - 8 S.
In: European journal of medicinal chemistry, ISSN 1768-3254. 176(2019), Seite 187-194
DOI: 10.1016/j.ejmech.2019.05.025
- Jakob, Alexander: Backbone modifications in peptidic inhibitors of flaviviral proteases / Alexander K.M.H. Jakob, Tom R. Sundermann, Christian D. Klein, August 2019. - 5 S.
In: Bioorganic & medicinal chemistry letters, ISSN 1464-3405. 29(2019), 15, Seite 1913-1917
DOI: 10.1016/j.bmcl.2019.05.054
- Monoclonal antibodies / special issue editor: Christian Klein. - First edition. -
Basel ; Beijing ; Wuhan ; Barcelona ; Belgrade: MDPI, 2018. - 1 Online-Ressource (viii, 224 Seiten) : Diagramme, ISBN 978-3-03842-876-3
- Klein, Christian D.: [Rezension von: Small molecule medicinal chemistry] / Prof. Christian Klein, Heidelberg University (Germany), 20 June 2017. - 1 S.
In: ChemMedChem, ISSN 1860-7187. 12(2017), 13, Seite 1101
DOI: 10.1002/cmdc.201700060
- Liang, Chen: Phenylglycine racemization in Fmoc-based solid-phase peptide synthesis : stereochemical stability is achieved by choice of reaction conditions / Chen Liang, Mira A.M. Behnam, Tom R. Sundermann, Christian D. Klein, 21 April 2017. - 5 S.
In: Tetrahedron letters, ISSN 1873-3581. 58(2017), 24, Seite 2325-2329
DOI: 10.1016/j.tetlet.2017.04.047
- Boldescu, Veaceslav: Broad-spectrum agents for flaviviral infections : dengue, Zika and beyond / Veaceslav Boldescu, Mira A.M. Behnam, Nikos Vasilakis, Christian D. Klein. - 22 S.
In: Nature reviews, ISSN 1474-1784. 16(2017), 8, S. 565-586
DOI: 10.1038/nrd.2017.33
- Mahawaththa, Mithun C.: Solution conformations of a linked construct of the Zika virus NS2B-NS3 protease / Mithun C. Mahawaththa, Benjamin J.G. Pearce, Monika Szabo, Bim Graham, Christian D. Klein, Christoph… , 21 March 2017. - 7 S.
In: Antiviral research, ISSN 1872-9096. 142(2017), Seite 141-147
DOI: 10.1016/j.antiviral.2017.03.011
- Nitsche, Christoph: Peptide-boronic acid inhibitors of flaviviral proteases : medicinal chemistry and structural biology / Christoph Nitsche, Linlin Zhang, Lena F. Weigel, Jonas Schilz, Dominik Graf, Ralf Bartenschlager, Ro… , January 12, 2017. - 6 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 60(2017), 1, Seite 511-516
DOI: 10.1021/acs.jmedchem.6b01021
- Osman, Noha: Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands : the structural elements controlling binding affinity, selectivity and functionality / Noha A. Osman, Alessia Ligresti, Christian D. Klein, Marco Allarà, Alessandro Rabbito, Vincenzo Di M… , 9 July 2016. - 16 S.
In: European journal of medicinal chemistry, ISSN 1768-3254. 122(2016), Seite 619-634
DOI: 10.1016/j.ejmech.2016.07.012
- Morgen, Michael: Spiroepoxytriazoles are fumagillin-like irreversible inhibitors of MetAP2 with potent cellular activity / Michael Morgen, Christian Jöst, Mona Malz, Robert Janowski, Dierk Niessing, Christian D. Klein, Niko… , 2016. - 11 S.
In: ACS chemical biology, ISSN 1554-8937. 11(2016), 4, Seite 1001-1011
DOI: 10.1021/acschembio.5b00755
- Lei, Jian: Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor / Jian Lei, Guido Hansen, Christoph Nitsche, Christian D. Klein, Linlin Zhang, Rolf Hilgenfeld, 14 July 2016. - 3 S.
In: Science, ISSN 1095-9203. 353(2016), 6298, Seite 503-505
DOI: 10.1126/science.aag2419
- Behnam, Mira A. M.: Solid phase synthesis of C-terminal boronic acid peptides / Mira A. M. Behnam, Tom R. Sundermann, and Christian D. Klein, April 22, 2016. - 4 S.
In: Organic letters, ISSN 1523-7052. 18(2016), 9, Seite 2016-2019
DOI: 10.1021/acs.orglett.6b00625
- Behnam, Mira A. M.: The medicinal chemistry of dengue virus / Mira A. M. Behnam, Christoph Nitsche, Veaceslav Boldescu, and Christian D. Klein, January 15, 2016. - 28 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 59(2016), 12, Seite 5622-5649
DOI: 10.1021/acs.jmedchem.5b01653
- Chen, Wan-Na: Sensitive NMR approach for determining the binding mode of tightly binding ligand molecules to protein targets / Wan-Na Chen, Christoph Nitsche, Kala Bharath Pilla, Bim Graham, Thomas Huber, Christian D. Klein and… , March 14, 2016. - 8 S.
In: Journal of the American Chemical Society, ISSN 1520-5126. 138(2016), 13, Seite 4539-4546
DOI: 10.1021/jacs.6b00416
- Calcagno, Sarah: N-Terminal methionine processing by the zinc-activated Plasmodium falciparum methionine aminopeptidase 1b / Sarah Calcagno & Christian D. Klein, 29 March 2016. - 12 S.
In: Applied microbiology and biotechnology, ISSN 1432-0614. 100(2016), 16, Seite 7091-7102
DOI: 10.1007/s00253-016-7470-3
- Weng, Zhibing: Identification of fused bicyclic derivatives of pyrrolidine and imidazolidinone as dengue virus-2 NS2B-NS3 protease inhibitors / Zhibing Weng, Xiaoxia Shao, Dominik Graf, Chunguang Wang, Christian D. Klein, Jing Wang, Guo-Chun Zh… . - 9 S.
In: European journal of medicinal chemistry, ISSN 1768-3254. 125(2017), S. 751-759
DOI: 10.1016/j.ejmech.2016.09.063
- Behnam, Mira A. M.: Discovery of nanomolar dengue and West Nile virus protease inhibitors containing a 4-benzyloxyphenylglycine residue / Mira A.M. Behnam, Dominik Graf, Ralf Bartenschlager, Darius P. Zlotos, and Christian D. Klein, November 12, 2015. - 17 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 58(2015), 23, Seite 9354-9370
DOI: 10.1021/acs.jmedchem.5b01441
- Weigel, Lena: Phenylalanine and phenylglycine analogues as arginine mimetics in dengue protease inhibitors / Lena F. Weigel, Christoph Nitsche, Dominik Graf, Ralf Bartenschlager, and Christian D. Klein, September 14, 2015. - 15 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 58(2015), 19, Seite 7719-7733
DOI: 10.1021/acs.jmedchem.5b00612
- Bastos Lima, Allan: Dual inhibitors of the dengue and West Nile virus NS2B-NS3 proteases : synthesis, biological evaluation and docking studies of novel peptide-hybrids / Allan Bastos Lima, Mira A.M. Behnam, Yasmin El Sherif, Christoph Nitsche, Sergio M. Vechi, Christian… , 15 July 2015. - 8 S.
In: Bioorganic & medicinal chemistry, ISSN 1464-3391. 23(2015), 17, Seite 5748-5755
DOI: 10.1016/j.bmc.2015.07.012
- Marschner, Aline: Metal promiscuity and metal-dependent substrate preferences of Trypanosoma brucei methionine aminopeptidase 1 / Aline Marschner, Christian D. Klein, 25 April 2015. - 9 S.
In: Biochimie. 115(2015), Seite 35-43
DOI: 10.1016/j.biochi.2015.04.012
- Altmeyer, Markus: Beta-aminoketones as prodrugs for selective irreversible inhibitors of type-1 methionine aminopeptidases / Markus Altmeyer, Eberhard Amtmann, Carina Heyl, Aline Marschner, Axel J. Scheidig, Christian D. Klei… , 23 September 2014. - 5 S.
In: Bioorganic & medicinal chemistry letters, ISSN 1464-3405. 24(2014), 22, Seite 5310-5314
DOI: 10.1016/j.bmcl.2014.09.047
- Behnam, Mira A. M.: C-Terminal residue optimization and fragment merging : discovery of a potent peptide-hybrid inhibitor of Dengue protease / Mira A. M. Behnam, Christoph Nitsche, Sérgio M. Vechi, Christian D. Klein, July 18, 2014. - 6 S. : Illustrationen
In: ACS medicinal chemistry letters, ISSN 1948-5875. 5(2014), 9, Seite 1037-1042
DOI: 10.1021/ml500245v
- Jöst, Christian: Promiscuity and selectivity in covalent enzyme inhibition : a systematic study of electrophilic fragments / Christian Jöst, Christoph Nitsche, Therese Scholz, Lionel Roux, and Christian D. Klein, August 22, 2014
In: Journal of medicinal chemistry, ISSN 1520-4804. 57(2014), 18, Seite 7590-7599$10
DOI: 10.1021/jm5006918
- Osman, Noha: Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligands / Noha A. Osman, Amr H. Mahmoud, Christian D. Klein, Marco Allarà, Vincenzo Di Marzo, Khaled M. Abouzi… , 31 July 2014. - 6 S.
In: MedChemComm, ISSN 2040-2511. 5(2014), 10, Seite 1571-1576
DOI: 10.1039/C4MD00232F
- Nitsche, Christoph: Biochemistry and medicinal chemistry of the dengue virus protease / Christoph Nitsche, Steven Holloway, Tanja Schirmeister, Christian D. Klein, September 30, 2014. - 34 S.
In: Chemical reviews, ISSN 1520-6890. 114(2014), 22, Seite 11348-11381
DOI: 10.1021/cr500233q
- Nitsche, Christoph: Fluorimetric and HPLC-based dengue virus protease assays using a FRET substrate / Christoph Nitsche and Christian D. Klein, 28 May 2013. - 16 S.
In: Antiviral methods and protocols. (2013), Seite 221-236
DOI: 10.1007/978-1-62703-484-5_18
- Scholz, Therese: Chemical, biochemical and microbiological properties of a brominated nitrovinylfuran with broad-spectrum antibacterial activity / Therese Scholz, Carina L. Heyl, Dan Bernardi, Stefan Zimmermann, Lars Kattner, Christian D. Klein, 2013. - 10 S.
In: Bioorganic & medicinal chemistry, ISSN 1464-3391. 21(2013), 3, Seite 795-804
DOI: 10.1016/j.bmc.2012.11.018
- Seehafer, Kai: Synthesis and biological properties of novel brefeldin a analogues / Kai Seehafer, Frank Rominger, Günter Helmchen, Markus Langhans, David G.Robinson, Başak Özata, Britt… . - 13 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 56(2013), 14, S. 5872-5884
DOI: 10.1021/jm400615g
- Nitsche, Christoph: Thiazolidinone-peptide hybrids as dengue virus protease inhibitors with antiviral activity in cell culture / Christoph Nitsche, Verena N. Schreier, Mira A. M. Behnam, Anil Kumar, Ralf Bartenschlager, and Chris… , 2013. - 15 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 56(2013), 21, Seite 8389-8403
DOI: 10.1021/jm400828u
- Mendgen, Thomas: Privileged scaffolds or promiscuous binders : a comparative study on rhodanines and related heterocycles in medicinal chemistry / Thomas Mendgen, Christian Steuer, and Christian D. Klein, 26 January 2012. - 11 S.
In: Journal of medicinal chemistry, ISSN 1520-4804. 55(2012), 2, Seite 743-753
DOI: 10.1021/jm201243p
- Nitsche, Christoph: Retro peptide-hybrids as selective inhibitors of the Dengue virus NS2B-NS3 protease / Christoph Nitsche, Mira A.M. Behnam, Christian Steuer, Christian D. Klein, 26 February 2012. - 8 S.
In: Antiviral research, ISSN 1872-9096. 94(2012), 1, Seite 72-79
DOI: 10.1016/j.antiviral.2012.02.008
- Nitsche, Christoph: Aqueous microwave-assisted one-pot synthesis of N-substituted rhodanines / Christoph Nitsche, Christian D. Klein. - 5 S.
In: Tetrahedron letters, ISSN 1873-3581. 53(2012), 39, S. 5197-5201
DOI: 10.1016/j.tetlet.2012.07.002
- Förster, Sebastian: Syntheses and biological properties of brefeldin analogues / Sebastian Förster, Elke Persch, Olena Tverskoy, Frank Rominger, Günter Helmchen, Christian Klein, Ba… , 2011. - 14 S.
In: European journal of organic chemistry, ISSN 1099-0690. 2011(2011), 5 vom: Feb., Seite 878-891
DOI: 10.1002/ejoc.201001297
- Steuer, Christian: Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture / Christian Steuer, Christian Gege, Wolfgang Fischl, Karl H. Heinonen, Ralf Bartenschlager, Christian … , 18 May 2011. - 8 S.
In: Bioorganic & medicinal chemistry, ISSN 1464-3391. 19(2011), 13, Seite 4067-4074
DOI: 10.1016/j.bmc.2011.05.015
- Nitsche, Christoph: Arylcyanoacrylamides as inhibitors of the Dengue and West Nile virus proteases / Christoph Nitsche, Christian Steuer, Christian D. Klein, 25 October 2011. - 10 S.
In: Bioorganic & medicinal chemistry, ISSN 1464-3391. 19(2011), 24, Seite 7318-7337
DOI: 10.1016/j.bmc.2011.10.061
- Poręba, Marcin: S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors / Marcin Poreba, Anna Gajda, Jan Picha, Jiri Jiracek, Aline Marschner, Christian D. Klein, Guy S. Salv… , 2012. - 7 S.
In: Biochimie. 94(2012), 3, Seite 704-710
DOI: 10.1016/j.biochi.2011.10.014
- Mendgen, Thomas: Structure-activity relationships of tulipalines, tuliposides, and related compounds as inhibitors of MurA / Thomas Mendgen, Therese Scholz, Christian D. Klein, 5 August 2010. - 6 S.
In: Bioorganic & medicinal chemistry letters, ISSN 1464-3405. 20(2010), 19, Seite 5757-5762
DOI: 10.1016/j.bmcl.2010.07.139
- Altmeyer, Markus: Subtype-selectivity of metal-dependent methionine aminopeptidase inhibitors / Markus A. Altmeyer, Aline Marschner, Rolf Schiffmann, Christian D. Klein, 27 May 2010. - 7 S.
In: Bioorganic & medicinal chemistry letters, ISSN 1464-3405. 20(2010), 14, Seite 4038-4044
DOI: 10.1016/j.bmcl.2010.05.093
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