heiBIB: Kool, Marcel

Kool, Marcel Dr.Universität HeidelbergHeidelberg

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Publikationen in heiBIB

Schwalbe, Edward C.: Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes : a multicenter cohort study / Edward C. Schwalbe, Janet C. Lindsey, Marina Danilenko, Rebecca M. Hill, Stephen Crosier, Sarra L. R… , January 2025. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 27(2025), 1, Seite 222-236
DOI: 10.1093/neuonc/noae178
Seiboldt, Till: Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours / Till Seiboldt, Constantia Zeiser, Duy Nguyen, Simay Celikyürekli, Sonja Herter, Sara Najafi, Alexand… , 28 June 2024. - 15 S. : Illustrationen
In: British journal of cancer, ISSN 1532-1827. 131(2024), 4, Seite 763-777
DOI: 10.1038/s41416-024-02740-5
Okonechnikov, Konstantin: Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations / Konstantin Okonechnikov, Daniel Schrimpf, Jan Koster, Philipp Sievers, Till Milde, Felix Sahm, David… , 07 June 2024. - 11 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 147(2024), Artikel-ID 95, Seite 1-11
DOI: 10.1007/s00401-024-02746-6
Gilbertson, Richard J.: The virtual child / Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, Henri… , April 04 2024. - 5 S. : Illustrationen
In: Cancer discovery, ISSN 2159-8290. 14(2024), 4 vom: Apr., Seite 663-668
DOI: 10.1158/2159-8290.CD-23-1500
Kolodziejczak, Anna: Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome / Anna S Kolodziejczak, Lea Guerrini-Rousseau, Julien Masliah Planchon, Jonas Ecker, Florian Selt, Mar… , December 2023. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 12 vom: Dez., Seite 2273-2286
DOI: 10.1093/neuonc/noad114
Mynarek, Martin: Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts / Martin Mynarek, Denise Obrecht, Martin Sill, Dominik Sturm, Katja Kloth-Stachnau, Florian Selt, Jona… , 2 December 2022. - 16 S. : Illustrationen, Diagramme
In: Acta neuropathologica, ISSN 1432-0533. 145(2023), 1, Seite 97-112
DOI: 10.1007/s00401-022-02522-4
Okonechnikov, Konstantin: 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma / Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin … , 21 April 2023. - 16 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 2300, Seite 1-16
DOI: 10.1038/s41467-023-38044-0
Okonechnikov, Konstantin: Mapping pediatric brain tumors to their origins in the developing cerebellum / Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, M… , October 2023. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 10 vom: Okt., Seite 1895-1909
DOI: 10.1093/neuonc/noad124
Nabbi, Arash: Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours / Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S.Y. … , 2023. - 24 S.
In: Genome medicine, ISSN 1756-994X. 15(2023), Artikel-ID 67, Seite 1-24
DOI: 10.1186/s13073-023-01219-x
Luo, Zaili: Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability / Zaili Luo, Dazhuan Xin, Yunfei Liao, Kalen Berry, Sean Ogurek, Feng Zhang, Liguo Zhang, Chuntao Zhao… , 10 February 2023. - 19 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 762, Seite 1-19
DOI: 10.1038/s41467-023-36400-8
Funke, Viktoria: Group-specific cellular metabolism in Medulloblastoma / Viktoria L.E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, … , 05 June 2023. - 16 S. : Illustrationen
In: Journal of translational medicine, ISSN 1479-5876. 21(2023), Artikel-ID 363, Seite 1-16
DOI: 10.1186/s12967-023-04211-6
Tauziède-Espariat, Arnault: CNS tumor with EP300 : :BCOR fusion: discussing its prevalence in adult population / Arnault Tauziède-Espariat, Emmanuelle Uro-Coste, Philipp Sievers, Yvan Nicaise, Cassandra Mariet, Au… , 13 February 2023. - 7 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 11(2023) vom: Feb., Artikel-ID 26, Seite 1-7
DOI: 10.1186/s40478-023-01523-y
Thatikonda, Venu: Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers / Venu Thatikonda, S.M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne N. Gröbner, Gregor W… , 26 January 2023. - 28 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 2 vom: Jan., Seite 276-289
DOI: 10.1038/s43018-022-00509-4
Bartl, Jasmin: The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors / Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picar… , 13 July 2022. - 15 S.
In: Nature Communications, ISSN 2041-1723. 13(2022) vom: Juli, Artikel-ID 4061, Seite 1-15
DOI: 10.1038/s41467-022-31574-z
Langenberg, Karin: Implementation of paediatric precision oncology into clinical practice : the individualized therapies for children with cancer program ‘iTHER’ / Karin P.S. Langenberg, Michael T. Meister, Jette J. Bakhuizen, Judith M. Boer, Natasha K.A. van Eijk… , 29 September 2022. - 15 S.
In: European journal of cancer, ISSN 1879-0852. 175(2022), Seite 311-325
DOI: 10.1016/j.ejca.2022.09.001
Juhnke, Björn-Ole: Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and highdose chemotherapy within the prospective P-HIT trial / B.-Ole Juhnke, Marco Gessi, Nicolas U. Gerber, Carsten Friedrich, Martin Mynarek, André O. von Buere… , January 2022. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 24(2022), 1, Seite 127-137
DOI: 10.1093/neuonc/noab100
Blümel, Lena: Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors / Lena Blümel, Nan Qin, Johannes Berlandi, Eunice Paisana, Rita Cascão, Carlos Custódia, David Pauck, … , 20 September 2022. - 13 S.
In: Cell death & disease, ISSN 2041-4889. 13(2022), 9, Artikel-ID 806, Seite 1-13
DOI: 10.1038/s41419-022-05243-4
Hasselblatt, Martin: SMARCB1-deficient and SMARCA4-deficient malignant brain tumors with complex copy number alterations and TP53 mutations may represent the first clinical manifestation of Li-Fraumeni syndrome / Martin Hasselblatt, MD, Christian Thomas, MD, Aniello Federico, PhD, Karolina Nemes, MD, Pascal D. J… , 2022. - 7 S.
In: The American journal of surgical pathology, ISSN 1532-0979. 46(2022), 9, Seite 1277-1283
DOI: 10.1097/PAS.0000000000001905
Delaidelli, Alberto: Clinically tractable outcome prediction of non-WNT/non-SHH medulloblastoma based on TPD52 IHC in a multicohort study / Alberto Delaidelli, Christopher Dunham, Mariarita Santi, Gian Luca Negri, Joanna Triscott, Olga Zhel… , January 05 2022. - 13 S.
In: Clinical cancer research, ISSN 1557-3265. 28(2022), 1, Seite 116-128
DOI: 10.1158/1078-0432.CCR-21-2057
Keller, Kaylee M.: Target actionability review : a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies / Kaylee M. Keller, Sonja Krausert, Apurva Gopisetty, Dan Luedtke, Jan Koster, Nil A. Schubert, Ana Ro… , 2022. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 162(2022) vom: Feb., Seite 107-117
DOI: 10.1016/j.ejca.2021.11.030
Miele, Evelina: Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth / Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi,… , February 2021. - 20 S. : Illustrationen
In: Molecular oncology, ISSN 1878-0261. 15(2021), 2 vom: Feb., Seite 523-542
DOI: 10.1002/1878-0261.12800
Simovic, Milena: Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model / Milena Simovic, Michiel Bolkestein, Mahmoud Moustafa, John K L Wong, Verena Körber, Sarah Benedetto,… , 28 May 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 12, Seite 2028-2041
DOI: 10.1093/neuonc/noab127
Williamson, Laura M.: Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury / Laura M. Williamson, Craig M. Rive, Daniela Di Francesco, Emma Titmuss, Hye-Jung E. Chun, Scott D. B… , 20 December 2021. - 12 S.
In: npj precision oncology, ISSN 2397-768X. 5(2021), Artikel-ID 103, Seite 1-12
DOI: 10.1038/s41698-021-00238-4
Adachi, Toma: Notch signaling between cerebellar granule cell progenitors / Toma Adachi, Satoshi Miyashita, Mariko Yamashita, Mana Shimoda, Konstantin Okonechnikov, Lukas Chave… , March 24, 2021. - 18 S.
In: eNeuro, ISSN 2373-2822. 8(2021), 3 vom: Mai/Juni, Seite 1-18
DOI: 10.1523/ENEURO.0468-20.2021
Panwalkar, Pooja: Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas / Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Siva Kumar Natarajan, Matthew… , 6 Oct 2021. - 13 S.
In: Science translational medicine, ISSN 1946-6242. 13(2021), 614, Artikel-ID eabc0497, Seite 1-13
DOI: 10.1126/scitranslmed.abc0497
Sievers, Philipp: Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors / Philipp Sievers, Sophie C. Henneken, Christina Blume, Martin Sill, Daniel Schrimpf, Damian Stichel, … , 05 August 2021. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 5, Seite 827-839
DOI: 10.1007/s00401-021-02356-6
Baroni, Lorena V.: Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q / Lorena V. Baroni, Lakshmikirupa Sundaresan, Ayala Heled, Hallie Coltin, Kristian W. Pajtler, Tong Li… , 13 February 2021. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 8, Seite 1360-1370
DOI: 10.1093/neuonc/noab034
Hoff, Katja von: Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities : results of an international, retrospective study / Katja von Hoff, Christine Haberler, Felix Schmitt-Hoffner, Elizabeth Schepke, Teresa de Rojas, Sandr… , 02 June 2021. - 15 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 9, Seite 1597-1611
DOI: 10.1093/neuonc/noab136
Zheng, Tuyu: Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas / Tuyu Zheng, David R. Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K. Maas… , April 20, 2021. - 18 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 9, Seite 2230-2247
DOI: 10.1158/2159-8290.CD-20-0963
Korshunov, Andrey: Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator / Andrey Korshunov, Konstantin Okonechnikov, Damian Stichel, Marina Ryzhova, Daniel Schrimpf, Felix Sa… , 16 February 2021. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 9, Seite 1576-1585
DOI: 10.1093/neuonc/noab031
Suwala, Abigail Kora: Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis / Abigail K. Suwala, Damian Stichel, Daniel Schrimpf, Matthias Kloor, Annika K. Wefers, Annekathrin Re… , 2021. - 16 S.
In: Acta neuropathologica, ISSN 1432-0533. 141(2021), 1, Seite 85-100
DOI: 10.1007/s00401-020-02243-6
Young, Matthew D.: Single cell derived mRNA signals across human kidney tumors / Matthew D. Young, Thomas J. Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez… , 23 June 2021. - 19 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 3896, Seite 1-19
DOI: 10.1038/s41467-021-23949-5
Thomas, Christian: The genetic landscape of choroid plexus tumors in children and adults / Christian Thomas, Patrick Soschinski, Melissa Zwaig, Spyridon Oikonomopoulos, Konstantin Okonechniko… , 2021. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 4 vom: Apr., Seite 650-660
DOI: 10.1093/neuonc/noaa267
Schmitt-Hoffner, Felix: FOXR2 stabilizes MYCN protein and identifies non-MYCN-amplified neuroblastoma patients with unfavorable outcome / Felix Schmitt-Hoffner, Sjoerd van Rijn, Umut H. Toprak, Monika Mauermann, Felix Rosemann, Anke Heit-… , June 10, 2021. - 12 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 29 vom: Okt., Seite 3217-3228
DOI: 10.1200/JCO.20.02540
Ecker, Jonas: Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma / Jonas Ecker, Venu Thatikonda, Gianluca Sigismondo, Florian Selt, Gintvile Valinciute, Ina Oehme, Car… , 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 2 vom: Feb., Seite 226-239
DOI: 10.1093/neuonc/noaa191
Kumar, Rahul: Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma / Rahul Kumar, PhD; Kyle S. Smith, PhD; Maximilian Deng, MD; Colt Terhune, BA; Giles W. Robinson, MD; … , January 27, 2021. - 18 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 7, Seite 807-821
DOI: 10.1200/JCO.20.01359
Kölsche, Christian: Sarcoma classification by DNA methylation profiling / Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam… , 21 January 2021. - 10 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 498, Seite 1-10
DOI: 10.1038/s41467-020-20603-4
Korshunov, Andrey: Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation / Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian… , 03 February 2021. - 12 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 9(2021), Artikel-ID 20, Seite 1-12
DOI: 10.1186/s40478-021-01118-5
Endersby, Raelene: Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma / Raelene Endersby, Jacqueline Whitehouse, Allison Pribnow, Mani Kuchibhotla, Hilary Hii, Brooke Carli… , 20 January 2021
In: Science translational medicine, ISSN 1946-6242. 13(2021), 577, Artikel-ID eaba7401, Seite 1-16
DOI: 10.1126/scitranslmed.aba7401
Rusert, Jessica M.: Functional precision medicine identifies new therapeutic candidates for medulloblastoma / Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, James Jensen, Alexandra Garancher, Lianne Q. … , October 12, 2020. - 15 S.
In: Cancer research, ISSN 1538-7445. 80(2020), 23, Seite 5393-5407
DOI: 10.1158/0008-5472.CAN-20-1655
Aichmüller, Christian Felix: Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response / Christian F Aichmüller, Murat Iskar, David TW Jones, Andrey Korshunov, Bernhard Radlwimmer, Marcel K… , 13 February 2020. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 9, Seite 1327-1338
DOI: 10.1093/neuonc/noaa035
Parisian, Alison: SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability / Alison D. Parisian, Tomoyuki Koga, Shunichiro Miki, Pascal D. Johann, Marcel Kool, John R. Crawford,… , September 10, 2020. - 14 S.
In: Genes & development, ISSN 1549-5477. 34(2020), 19/20, Seite 1316-1329
DOI: 10.1101/gad.339978.120
Mynarek, Martin: Nonmetastatic medulloblastoma of early childhood : results from the prospective clinical trial HIT-2000 and an extended validation cohort / Martin Mynarek, MD; Katja von Hoff, MD; Torsten Pietsch, MD; Holger Ottensmeier, PhD; Monika Warmuth… , April 24, 2020. - 13 S.
In: Journal of clinical oncology, ISSN 1527-7755. 38(2020), 18, Seite 2028-2040
DOI: 10.1200/JCO.19.03057
Gojo, Johannes: Single-cell RNA-seq reveals cellular hierarchies and impaired developmental trajectories in pediatric ependymoma / Johannes Gojo, Bernhard Englinger, Li Jiang, Jens M. Hübner, McKenzie L. Shaw, Olivia A. Hack, Sibyl… , July 13, 2020. - 25 S.
In: Cancer cell, ISSN 1878-3686. 38(2020), 1, Seite 44-59.e9
DOI: 10.1016/j.ccell.2020.06.004
Kutscher, Lena: Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation / Lena M. Kutscher, Konstantin Okonechnikov, Nadja V. Batora, Jessica Clark, Patricia B. G. Silva, Mik… , August 20, 2020. - 16 S.
In: Genes & development, ISSN 1549-5477. 34(2020), 17/18, Seite 1161-1176
DOI: 10.1101/gad.337584.120
Waszak, Sebastian Martin: Germline elongator mutations in Sonic Hedgehog medulloblastoma / Sebastian M. Waszak, Robinson Giles W, Brian L. Gudenas, Kyle S. Smith, Antoine Forget, Marija Kojic… , 01 April 2020. - 21 S.
In: Nature, ISSN 1476-4687. 580(2020), 7803, Seite 396-401
DOI: 10.1038/s41586-020-2164-5
Deng, Maximilian: Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC) - a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14 / M.Y. Deng, M. Sill, D. Sturm, D. Stichel, H. Witt, J. Ecker, A. Wittmann, J. Schittenhelm, M. Ebinge… , 2020
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 46(2020), 5, Seite 422-430
DOI: 10.1111/nan.12590
Pfaff, Elke: Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations / Elke Pfaff, Christian Aichmüller, Martin Sill, Damian Stichel, Matija Snuderl, Matthias A. Karajanni… , [2020]. - 15 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 2, Seite 243-257
DOI: 10.1007/s00401-019-02101-0
Ghasemi, David R.: MYCN amplification drives an aggressive form of spinal ependymoma / David R. Ghasemi, Martin Sill, Konstantin Okonechnikov, Andrey Korshunov, Stephen Yip, Peter W. Schu… , 14 August 2019. - 15 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 6, Seite 1075-1089
DOI: 10.1007/s00401-019-02056-2
Jaju, Alok: MRI features of histologically diagnosed supratentorial primitive neuroectodermal tumors and pineoblastomas in correlation with molecular diagnoses and outcomes : a report from the Children's Oncology Group ACNS0332 trial / A. Jaju, E.I. Hwang, M. Kool, D. Capper, L. Chavez, S. Brabetz, C. Billups, Y. Li, M. Fouladi, R.J. … , 1 Nov 2019. - 8 S.
In: American journal of neuroradiology, ISSN 1936-959X. 40(2019), 11, Seite 1796-1803
DOI: 10.3174/ajnr.A6253
Frühwald, Michael: Age and DNA methylation subgroup as potential independent risk factors for treatment stratification in children with atypical teratoid/rhabdoid tumors / Michael C. Frühwald, Martin Hasselblatt, Karolina Nemes, Susanne Bens, Mona Steinbügl, Pascal D. Joh… , 2020. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 7, Seite 1006-1017
DOI: 10.1093/neuonc/noz244
Ho, Ben: Molecular subgrouping of atypical teratoid/rhabdoid tumors : a reinvestigation and current consensus / Ben Ho, Pascal D. Johann, Yura Grabovska, Mamy Jean De Dieu Andrianteranagna, Fupan Yao, Michael Frü… , 2020. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 5, Seite 613-624
DOI: 10.1093/neuonc/noz235
Thomas, Christian: Desmoplastic myxoid tumor, SMARCB1-mutant : clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults / Christian Thomas, Annika Wefers, Susanne Bens, Karolina Nemes, Abbas Agaimy, Florian Oyen, Silke Vog… , [2020]. - 10 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 2, Seite 277-286
DOI: 10.1007/s00401-019-02094-w
Chun, Hye-Jung E.: Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration / Hye-Jung E. Chun, Pascal D. Johann, Katy Milne, Marc Zapatka, Annette Buellesbach, Naveed Ishaque, M… , 7 November, 2019. - 24 S.
In: Cell reports, ISSN 2211-1247. 29(2019), 8, Seite 2338-2354.e1-e7
DOI: 10.1016/j.celrep.2019.10.013
Jones, David T. W.: Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours / David T.W. Jones, Ana Banito, Thomas G.P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Til… , 12 July 2019. - 19 S.
In: Nature reviews, ISSN 1474-1768. 19(2019), 8, Seite 420-438
DOI: 10.1038/s41568-019-0169-x
Sharma, Tanvi: Second-generation molecular subgrouping of medulloblastoma : an international meta-analysis of Group 3 and Group 4 subtypes / Tanvi Sharma, Edward C. Schwalbe, Daniel Williamson, Martin Sill, Volker Hovestadt, Martin Mynarek, … , 10 May 2019. - 18 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 309-326
DOI: 10.1007/s00401-019-02020-0
Wirthschaft, Peter: RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas / Peter Wirthschaft, Julia Bode, Himanshu Soni, Fabio Dietrich, Thomas Krüwel, Bernd Fischer, Christia… , 2019. - 19 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 275-293
DOI: 10.1007/s00401-019-02021-z
Korshunov, Andrey: Molecular progression of SHH-activated medulloblastomas / Andrey Korshunov, Konstantin Okonechnikov, Felix Sahm, Marina Ryzhova, Damian Stichel, Philipp Sieve… , 27 April 2019. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 327-330
DOI: 10.1007/s00401-019-02022-y
Hübner, Jens-Martin: EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma / Jens-Martin Hübner, Torsten Müller, Dimitris N Papageorgiou, Monika Mauermann, Jeroen Krijgsveld, Ro… , 29 April 2019. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 21(2019), 7, Seite 878-889
DOI: 10.1093/neuonc/noz058
Benesch, Martin: Newly diagnosed metastatic intracranial ependymoma in children : frequency, molecular characteristics, treatment, and outcome in the prospective HIT series / Martin Benesch, Martin Mynarek, Hendrik Witt, Monika Warmuth‐Metz, Torsten Pietsch, Brigitte Bison, … , March 8, 2019. - 9 S.
In: The oncologist, ISSN 1549-490X. 24(2019), 9, Seite e921-e929
DOI: 10.1634/theoncologist.2018-0489
Huang, Miller: Engineering genetic predisposition in human neuroepithelial stem cells recapitulates medulloblastoma tumorigenesis / Miller Huang, Jignesh Tailor, Qiqi Zhen, Aaron H. Gillmor, Matthew L. Miller, Holger Weishaupt, Just… , 13 June 2019. - 22 S.
In: Cell stem cell, ISSN 1875-9777. 25(2019), 3, Seite 433-446.e7
DOI: 10.1016/j.stem.2019.05.013
Korshunov, Andrey: Integrated molecular characterization of IDH-mutant glioblastomas / A. Korshunov, B. Casalini, L. Chavez, T. Hielscher, M. Sill, M. Ryzhova, T. Sharma, D. Schrimpf, D. … , 2019. - 11 S.
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 45(2019), 2, Seite 108-118
DOI: 10.1111/nan.12523
Pagès, Mélanie: Diagnostics of pediatric supratentorial RELA ependymomas : integration of information from histopathology, genetics, DNA methylation and imaging / Mélanie Pagès; Kristian W. Pajtler; Stéphanie Puget; David Castel; Nathalie Boddaert; Arnault Tauziè… , 2019. - 11 S.
In: Brain pathology, ISSN 1750-3639. 29(2019), 3, Seite 325-335
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In: Cell, ISSN 1097-4172. 153(2013), 5 vom: Mai, Seite 1064-1079
DOI: 10.1016/j.cell.2013.04.055
Rieber, Nora: Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies / Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul Northcott, Barbara Hutter, Natalie J… , June 11, 2013. - 11 S.
In: PLOS ONE, ISSN 1932-6203. 8(2013), 6, Artikel-ID e66621, Seite 1-11
DOI: 10.1371/journal.pone.0066621
Remke, Marc: Somatostatin receptor subtype 2 (sst2) is a potential prognostic marker and a therapeutic target in medulloblastoma / Marc Remke · Esther Hering · Nicolas U. Gerber · Marcel Kool · Dominik Sturm · Christian H. Rickert … , 16 May 2013. - 10 S.
In: Child's nervous system, ISSN 1433-0350. 29(2013), 8, Seite 1253-1262
DOI: 10.1007/s00381-013-2142-4
Reuss, David: Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations / David E. Reuss, Rosario M. Piro, David T.W. Jones, Matthias Simon, Ralf Ketter, Marcel Kool, Albert … , 12 February 2013. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 351-358
DOI: 10.1007/s00401-013-1093-x
Remke, Marc: TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma / Marc Remke, Vijay Ramaswamy, John Peacock, David J.H. Shih, Christian Koelsche, Paul A. Northcott, N… , 31 October 2013. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 6, Seite 917-929
DOI: 10.1007/s00401-013-1198-2
Ramaswamy, Vijay: Recurrence patterns across medulloblastoma subgroups : an integrated clinical and molecular analysis / Vijay Ramaswamy, Marc Remke, Eric Bouffet, Claudia C Faria, Sebastien Perreault, Yoon-Jae Cho, David… , October 17, 2013. - 8 S.
In: The lancet, ISSN 1474-5488. 14(2013), 12 vom: Nov., Seite 1200-1207
DOI: 10.1016/S1470-2045(13)70449-2
Oehme, Ina: Histone deacetylase 10 promotes autophagy-mediated cell survival / Ina Oehme, Jan-Peter Linke, Barbara C. Böck, Till Milde, Marco Lodrini, Bettina Hartenstein, Inga Wi… , June 25, 2013. - 10 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 110(2013), 28, Seite E2592-E2601
DOI: 10.1073/pnas.1300113110
Hovestadt, Volker: Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays / Volker Hovestadt, Marc Remke, Marcel Kool, Torsten Pietsch, Paul A. Northcott, Roger Fischer, Floren… , 14 May 2013. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 6, Seite 913-916
DOI: 10.1007/s00401-013-1126-5
Lambert, Sally R.: Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma / Sally R. Lambert, Hendrik Witt, Volker Hovestadt, Manuela Zucknick, Marcel Kool, Danita M. Pearson, … , 10 May 2013. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 2 vom: Aug., Seite 291-301
DOI: 10.1007/s00401-013-1124-7
Alexandrov, Ludmil: Corrigendum : Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 9 October 2013. - 1 S.
In: Nature, ISSN 1476-4687. 502(2013), 7470, Seite 258-258
DOI: 10.1038/nature12666
Alexandrov, Ludmil: Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 14 August 2013. - 7 S.
In: Nature, ISSN 1476-4687. 500(2013), 7463, Seite 415-421
DOI: 10.1038/nature12477
Jones, David T. W.: The role of chromatin remodeling in medulloblastoma / David T.W. Jones; Paul A. Northcott; Marcel Kool; Stefan M. Pfister, 25 February 2013. - 7 S.
In: Brain pathology, ISSN 1750-3639. 23(2013), 2 vom: März, Seite 193-199
DOI: 10.1111/bpa.12019
Dykhuizen, Emily C.: BAF complexes facilitate decatenation of DNA by topoisomerase IIα / Emily C. Dykhuizen, Diana C. Hargreaves, Erik L. Miller, Kairong Cui, Andrey Korshunov, Marcel Kool,… , 22 May 2013. - 4 S.
In: Nature, ISSN 1476-4687. 497(2013), 7451, Seite 624-627
DOI: 10.1038/nature12146
Dubuc, Adrian M.: Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma / Adrian M. Dubuc, Marc Remke, Andrey Korshunov, Paul A. Northcott, Shing H. Zhan, Maria Mendez-Lago, … , 2013. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 373-384
DOI: 10.1007/s00401-012-1070-9
Bender, Sebastian: Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas / Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, David T.W. Jones, Marcel Kool, M… , October 31, 2013. - 13 S.
In: Cancer cell, ISSN 1878-3686. 24(2013), 5, Seite 660-672
DOI: 10.1016/j.ccr.2013.10.006
Oehme, Ina: Histone deacetylase 10 promotes autophagy-mediated cell survival / Ina Oehme, Jan-Peter Linke, Barbara C. Böck, Till Milde, Marco Lodrini, Bettina Hartenstein, Inga Wi… , 2013. - 10 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424. 110(2013), 28, Seite E2592-E2601
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 2012. - 6 S.
In: Nature, ISSN 0028-0836. 488(2012), 7409 vom: 20. Juni, Seite 100-105
Milde, Till: HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment / Till Milde, Marco Lodrini, Larissa Savelyeva, Andrey Korshunov, Marcel Kool, Lena M. Brueckner, Andr… , December 2012. - 14 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 110(2012), 3, Seite 335-348
DOI: 10.1007/s11060-012-0978-1
Milde, Till: Nestin expression identifies ependymoma patients with poor outcome / Till Milde, Thomas Hielscher, Hendrik Witt, Marcel Kool, Stephen C. Mack, Hedwig E. Deubzer, Ina Oeh… , 09 May 2012. - 13 S.
In: Brain pathology, ISSN 1750-3639. 22(2012), 6, Seite 848-860
DOI: 10.1111/j.1750-3639.2012.00600.x
Korshunov, Andrey: LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) / Andrey Korshunov, Marina Ryzhova, David T. W. Jones, Paul A. Northcott, Peter van Sluis, Richard Vol… , 16 November 2012. - 7 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 6, Seite 875-881
DOI: 10.1007/s00401-012-1068-3
Korshunov, Andrey: Biological and clinical heterogeneity of MYCN-amplified medulloblastoma / Andrey Korshunov, Marc Remke, Marcel Kool, Thomas Hielscher, Paul A. Northcott, Dan Williamson, Elke… , 2012. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 515-527
DOI: 10.1007/s00401-011-0918-8
Kool, Marcel: Molecular subgroups of medulloblastoma : an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas / Marcel Kool, Andrey Korshunov, Marc Remke, David T.W. Jones, Maria Schlanstein, Paul A. Northcott, Y… , 23 February 2012. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 473-484
DOI: 10.1007/s00401-012-0958-8
Liu, Xiao-Yang: Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations / Xiao-Yang Liu, Noha Gerges, Andrey Korshunov, Nesrin Sabha, Dong-Anh Khuong-Quang, Adam M. Fontebass… , 12 August 2012. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 5, Seite 615-625
DOI: 10.1007/s00401-012-1031-3
Bai, Alfa H. C.: MicroRNA-182 promotes leptomeningeal spread of non-Sonic Hedgehog-medulloblastoma / Alfa H. C. Bai, Till Milde, Marc Remke, Claudio G. Rolli, Thomas Hielscher, Yoon-Jae Cho, Marcel Koo… , 2012. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 529-538
DOI: 10.1007/s00401-011-0924-x
Northcott, Paul A.: Medulloblastomics : the end of the beginning / Paul A. Northcott, David T.W. Jones, Marcel Kool, Giles W. Robinson, Richard J. Gilbertson, Yoon-Jae… , 23 November 2012. - 17 S.
In: Nature reviews, ISSN 1474-1768. 12(2012), 12, Seite 818-834
DOI: 10.1038/nrc3410
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 25 July 2012. - 6 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 100-105
DOI: 10.1038/nature11284
Khuong-Quang, Dong-Anh: K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas / Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M. Fontebasso, Eri… , 3 June 2012. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 3, Seite 439-447
DOI: 10.1007/s00401-012-0998-0
Schwartzentruber, Jeremy: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma / Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T.W. Jones, Elke Pfaff, Karine Jacob… , 29 January 2012. - 6 S.
In: Nature, ISSN 1476-4687. 482(2012), 7384, Seite 226-231
DOI: 10.1038/nature10833
Grammel, Daniel: Sonic Hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem / Daniel Grammel, Monika Warmuth-Metz, André O. von Bueren, Marcel Kool, Torsten Pietsch, Hans A. Kret… , 21 February 2012. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 601-614
DOI: 10.1007/s00401-012-0961-0
Northcott, Paul A.: Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples / Paul A. Northcott, David J.H. Shih, Marc Remke, Yoon-Jae Cho, Marcel Kool, Cynthia Hawkins, Charles … , April 2012. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 615-626
DOI: 10.1007/s00401-011-0899-7
Sturm, Dominik: Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma / Dominik Sturm; Hendrik Witt ... David T. W. Jones; Carolin Konermann; Elke Pfaff ... Sebastian Bende… , October 15, 2012. - 13 S.
In: Cancer cell, ISSN 1878-3686. 22(2012), 4, Seite 425-437
DOI: 10.1016/j.ccr.2012.08.024
Vuurden, Dannis G. van: PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation / Dannis G. van Vuurden, Esther Hulleman, Olga L.M. Meijer, Laurine E. Wedekind, Marcel Kool, Hendrik … , December 15, 2011. - 13 S.
In: OncoTarget, ISSN 1949-2553. 2(2011), 12, Seite 984-996
DOI: 10.18632/oncotarget.362
Remke, Marc: FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma / Marc Remke, Thomas Hielscher, Andrey Korshunov, Paul A. Northcott, Sebastian Bender, Marcel Kool, Fr… , September 12, 2011. - 10 S.
In: Journal of clinical oncology, ISSN 1527-7755. 29(2011), 29, Seite 3852-3861
DOI: 10.1200/JCO.2011.36.2798
Taylor, Michael D.: Molecular subgroups of medulloblastoma : the current consensus / Michael D. Taylor, Paul A. Northcott, Andrey Korshunov, Marc Remke, Yoon-Jae Cho, Steven C. Clifford… , 2012. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 465-472
DOI: 10.1007/s00401-011-0922-z
Pfister, Stefan: Molecular diagnostics of CNS embryonal tumors / Stefan M. Pfister, Andrey Korshunov, Marcel Kool, Martin Hasselblatt, Charles Eberhart, Michael D. T… , 30 September 2010. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 120(2010), 5 vom: Sept., Seite 553-566
DOI: 10.1007/s00401-010-0751-5

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