
Burhenne, Jürgen Dr. rer. nat.Universität HeidelbergHeidelberg
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- Fresnais, Margaux (19)
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Publications in heiBIB 
- Hose, Dirk: Correction: Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma / Dirk Hose, Seemun Ray, Sina Rößler, Ulrich Thormann, Reinhard Schnettler, Kim de Veirman, Thaqif El … , 24 January 2025. - 1 S.
In: Journal of hematology & oncology, ISSN 1756-8722. 18(2025), Artikel-ID 11, Seite 1
DOI: 10.1186/s13045-025-01663-9
- Krohmer, Evelyn: Influence of a short course of ritonavir used as booster in antiviral therapies against SARS-CoV-2 on the exposure of atorvastatin and rosuvastatin / Evelyn Krohmer, Brit Silja Rohr, Felicitas Stoll, Katja S. Gümüs, Mariano Bergamino, Gerd Mikus, Max… , 2025. - 11 S. : Illustrationen
In: Cardiovascular drugs and therapy, ISSN 1573-7241. 39(2025), Seite 325–335
DOI: 10.1007/s10557-023-07538-w
- Bajraktari-Sylejmani, Gzona: A highly sensitive UPLC-MS/MS method for the quantification of the organic cation transporters' mediated metformin uptake and its inhibition in cells / Gzona Bajraktari-Sylejmani, Cindy Bay, Lukas Gebauer, Jürgen Burhenne, Johanna Weiss and Max Sauter, 2024. - 14 S. : Diagramme
In: Molecules, ISSN 1420-3049. 29(2024), 21, Artikel-ID 5162, Seite [1]-14
DOI: 10.3390/molecules29215162
- Hohmann, Nicolas: Dose-dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin / Nicolas Hohmann, Anna S. Friedrichs, Jürgen Burhenne, Antje Blank, Gerd Mikus, Walter E. Haefeli, August 2024. - 11 S. : Diagramme
In: Clinical and translational science, ISSN 1752-8062. 17(2024), 8 vom: Aug., Artikel-ID e70007, Seite 1-11
DOI: 10.1111/cts.70007
- Hose, Dirk: Bortezomib-releasing silica-collagen xerogels for local treatment of osteolytic bone- and minimal residual disease in multiple myeloma / Dirk Hose, Seemun Ray, Sina Rößler, Ulrich Thormann, Reinhard Schnettler, Kim de Veirman, Thaqif El … , 18 December 2024. - 20 S. : Illustrationen
In: Journal of hematology & oncology, ISSN 1756-8722. 17(2024), Artikel-ID 128, Seite 1-20
DOI: 10.1186/s13045-024-01636-4
- Rohr, Brit Silja: Time course of the interaction between oral short-term ritonavir therapy with three factor Xa inhibitors and the activity of CYP2D6, CYP2C19, and CYP3A4 in healthy volunteers / Brit S. Rohr, Evelyn Krohmer, Kathrin I. Foerster, Jürgen Burhenne, Martin Schulz, Antje Blank, Gerd… , 23 February 2024. - 13 S. : Illustrationen
In: Clinical pharmacokinetics, ISSN 1179-1926. 63(2024), 4, Seite 469-481
DOI: 10.1007/s40262-024-01350-x
- Rose, Fabian: RNA is a pro-apoptotic target of cisplatin in cancer cell lines and C. elegans / Fabian Rose, Beate Köberle, Sebastian Honnen, Cindy Bay, Jürgen Burhenne, Johanna Weiss, Walter E. H… , 18 March 2024. - 10 S.
In: Biomedicine & pharmacotherapy, ISSN 1950-6007. 173(2024), Artikel-ID 116450, Seite 116450-1-116450-10
DOI: 10.1016/j.biopha.2024.116450
- Rigalli, Juan Pablo: Extracellular vesicles as surrogates for the regulation of the drug transporters ABCC2 (MRP2) and ABCG2 (BCRP) / Juan Pablo Rigalli, Anna Gagliardi, Klara Diester, Gzona Bajraktari-Sylejmani, Antje Blank, Jürgen B… , 8 April 2024. - 18 S.
In: International journal of molecular sciences, ISSN 1422-0067. 25(2024), 7, Artikel-ID 4118, Seite 1-18
DOI: 10.3390/ijms25074118
- Bajraktari-Sylejmani, Gzona: In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo-keto reductases / Gzona Bajraktari-Sylejmani, Julia Sophie Oster, Jürgen Burhenne, Walter Emil Haefeli, Max Sauter, Jo… , 4 January 2024. - 14 S. : Illustrationen
In: Archives of toxicology, ISSN 1432-0738. 98(2024), 3, Seite 807-820
DOI: 10.1007/s00204-023-03661-7
- Stoll, Felicitas E.: Evaluation of hydroxychloroquine as a perpetrator on cytochrome P450 (CYP) 3A and CYP2D6 activity with microdosed probe drugs in healthy volunteers / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Johanna Weiss, Marleen J. Meyer-Tönnies, Katj… , January 2024. - 9 S. : Illustrationen
In: European journal of drug metabolism and pharmacokinetics, ISSN 2107-0180. 49(2024), 1, Seite 101-109
DOI: 10.1007/s13318-023-00872-2
- Gümüs, Katja S.: Effect of tacrolimus formulation (prolonged-release vs immediate-release) on its susceptibility to drug-drug interactions with St. John's Wort / Katja S. Gümüs, Anna Teegelbekkers, Max Sauter, Andreas D. Meid, Jürgen Burhenne, Johanna Weiss, Ant… , 04 January 2024. - 10 S.
In: Clinical pharmacology in drug development, ISSN 2160-7648. 13(2024), Seite 1-10
DOI: 10.1002/cpdd.1364
- Longuespée, Rémi: Therapeutic drug monitoring of osimertinib in non-small cell lung cancer and short bowel syndrome : a case report / Rémi Longuespée, Julia Kunz, Margaux Fresnais, Kathrin I. Foerster, Jürgen Burhenne, Michael Thomas,… , January 2024. - 6 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 90(2024), 1, Seite 344-349
DOI: 10.1111/bcp.15924
- Zhou, Xu: Persister cell phenotypes contribute to poor patient outcomes after neoadjuvant chemotherapy in PDAC / Xu Zhou, Jingyu An, Roma Kurilov, Benedikt Brors, Kai Hu, Teresa Peccerella, Stephanie Roessler, Kat… , 7 September 2023. - 20 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 9, Seite 1362-1381
DOI: 10.1038/s43018-023-00628-6
- Fresnais, Margaux: Quantification of biologically active DNA alkylation in temozolomide-exposed glioblastoma cell lines by ultra-performance liquid chromatography-tandem mass spectrometry : method development and recommendations for validation / Margaux Fresnais, Ina Jung, Uli B. Klein, Dirk Theile, Siwen Liang, Walter E. Haefeli, Jürgen Burhen… , June 23, 2023. - 11 S.
In: ACS omega, ISSN 2470-1343. 8(2023), 26, Seite 23695-23705
DOI: 10.1021/acsomega.3c01818
- Fresnais, Margaux: Desorption kinetics evaluation for the development of validated desorption electrospray ionization-mass spectrometric assays for drug quantification in tissue sections / Margaux Fresnais, Siwen Liang, Deniz Seven, Nevena Prodanovic, Julia Sundheimer, Walter E. Haefeli, … , 9 May 2023. - 14 S. : Illustrationen
In: International journal of molecular sciences, ISSN 1422-0067. 24(2023), 10, Artikel-ID 8469, Seite 1-14
DOI: 10.3390/ijms24108469
- Zhu, Vanessa: Evaluation of the drug-drug interaction potential of the novel hepatitis B and D virus entry inhibitor bulevirtide at OATP1B in healthy volunteers / Vanessa Zhu, Jürgen Burhenne, Johanna Weiss, Mathias Haag, Ute Hofmann, Matthias Schwab, Stephan Urb… , 6 April 2023. - 13 S.
In: Frontiers in pharmacology, ISSN 1663-9812. 14(2023) vom: Apr., Artikel-ID 1128547, Seite 1-13
DOI: 10.3389/fphar.2023.1128547
- Bay, Cindy: Correction : Bay et al. functional characterization of the solute carrier LAT-1 (SLC7A5/SLC3A2) in human brain capillary endothelial cells with rapid UPLC-MS/MS quantification of intracellular isotopically labelled L-leucine. Int. J. Mol. Sci. 2022, 23, 3637 / Cindy Bay, Gzona Bajraktari-Sylejmani, Walter E. Haefeli, Jürgen Burhenne, Johanna Weiss and Max Sau… , 6 March 2023. - 1 S.
In: International journal of molecular sciences, ISSN 1422-0067. 24(2023), 5, Artikel-ID 5029, Seite 1
DOI: 10.3390/ijms24055029
- Fresnais, Margaux: Important requirements for desorption/ionization mass spectrometric measurements of temozolomide-induced 2′-deoxyguanosine methylations in DNA / Margaux Fresnais, Ina Jung, Uli B. Klein, Aubry K. Miller, Sevin Turcan, Walter E. Haefeli, Jürgen B… , 24 January 2023. - 15 S.
In: Cancers, ISSN 2072-6694. 15(2023), 3, Artikel-ID 716, Seite 1-15
DOI: 10.3390/cancers15030716
- Stoll, Felicitas E.: Effect of pantoprazole on the absorption of Hydroxychloroquinea A randomized drug-drug interaction trial in healthy adults / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Kathrin I. Foerster, Simon Hermann, Katja Güm… , 2022. - 6 S.
In: Clinical pharmacology in drug development, ISSN 2160-7648. 11(2022), 2, Seite 285-290
DOI: 10.1002/cpdd.999
- Stoll, Felicitas E.: Metabolic effect of blocking sodium-taurocholate co-transporting polypeptide in hypercholesterolemic humans with a twelve-week course of bulevirtide : n exploratory phase I clinical trial / Felicitas Stoll, Andrea Seidel-Glätzer, Ina Burghaus, Oliver Göring, Max Sauter, Peter Rose, Volker … , 14 December 2022. - 16 S.
In: International journal of molecular sciences, ISSN 1422-0067. 23(2022), 24, Artikel-ID 15924, Seite 1-16
DOI: 10.3390/ijms232415924
- Rohr, Brit Silja: Perpetrator characteristics of azole antifungal drugs on three oral factor Xa inhibitors administered as a microdosed cocktail / Brit Silja Rohr, Kathrin Isabelle Foerster, Antje Blank, Jürgen Burhenne, Mazyar Mahmoudi, Walter Em… , 2022. - 13 S.
In: Clinical pharmacokinetics, ISSN 1179-1926. 61(2022), 1, Seite 97-109
DOI: 10.1007/s40262-021-01051-9
- Bajraktari-Sylejmani, Gzona: Evaluation of PepT1 (SLC15A1) substrate characteristics of therapeutic cyclic peptides / Gzona Bajraktari-Sylejmani, Teresa von Linde, Jürgen Burhenne, Walter Emil Haefeli, Max Sauter, Joha… , 1 August 2022. - 11 S.
In: Pharmaceutics, ISSN 1999-4923. 14(2022), 8, Artikel-ID 1610, Seite 1-11
DOI: 10.3390/pharmaceutics14081610
- Fresnais, Margaux: Analytical performance evaluation of new DESI enhancements for targeted drug quantification in tissue sections / Margaux Fresnais, Siwen Liang, Marius Breitkopf, Joshua Raoul Lindner, Emmanuelle Claude, Steven Pri… , 1 June 2022. - 18 S.
In: Pharmaceuticals, ISSN 1424-8247. 15(2022), 6, special issue, Artikel-ID 694, Seite 1-18
DOI: 10.3390/ph15060694
- Weiß, Johanna: Does the circulating ketoconazole metabolite N-deacetyl ketoconazole contribute to the drug-drug interaction potential of the parent compound? / Johanna Weiss, Kathrin Isabelle Foerster, Maria Weber, Jürgen Burhenne, Gerd Mikus, Thorsten Lehr, W… , 2022. - 8 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 169(2022), Artikel-ID 106076, Seite 1-8
DOI: 10.1016/j.ejps.2021.106076
- Rizos, Timolaos: Low exposure to direct oral anticoagulants is associated with ischemic stroke and its severity / Timolaos Rizos, Andreas D. Meid, Andrea Huppertz, Chris Dumschat, Jan Purrucker, Kathrin I. Foerster… , January 31, 2022. - 17 S.
In: Journal of stroke, ISSN 2287-6405. 24(2022), 1 vom: Jan., Seite 88-97, 1-7
DOI: 10.5853/jos.2020.04952
- Kraft, Manuel: Simultaneous quantification and pharmacokinetic characterization of doxapram and 2-ketodoxapram in porcine plasma and brain tissue / Manuel Kraft, Kathrin I. Foerster, Felix Wiedmann, Max Sauter, Amelie Paasche, Pablo L. Blochberger,… , 31 March 2022. - 13 S.
In: Pharmaceutics, ISSN 1999-4923. 14(2022), 4 vom: Apr., Artikel-ID 762, Seite 1-13
DOI: 10.3390/pharmaceutics14040762
- Alborzinia, Hamed: MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis / Hamed Alborzinia, Andrés F. Flórez, Sina Kreth, Lena M. Brückner, Umut Yildiz, Moritz Gartlgruber, D… , 28 April 2022. - 15 S.
In: Nature cancer, ISSN 2662-1347. 3(2022), 4, Seite 471-485
DOI: 10.1038/s43018-022-00355-4
- Bay, Cindy: Functional characterization of the aolute carrier LAT-1 (SLC7A5/SLC2A3) in human brain capillary endothelial cells with rapid UPLC-MS/MS quantification of intracellular isotopically labelled L-Leucine / Cindy Bay, Gzona Bajraktari-Sylejmani, Walter E. Haefeli, Jürgen Burhenne, Johanna Weiss and Max Sau… , 26 March 2022. - 18 S.
In: International journal of molecular sciences, ISSN 1422-0067. 23(2022), 7, Artikel-ID 3637, Seite 1-18
DOI: 10.3390/ijms23073637
- Fresnais, Margaux: Important requirements for the selection of internal standards during the development of desorption/ionization assays for drug quantification in biological matrices : a practical example / Margaux Fresnais, Seda Karabulut, Yasmin Abou Zeed, Johannes Ungermann, Julia Benzel, Kristian W. Pa… , 21 January 2022. - 13 S.
In: Molecules, ISSN 1420-3049. 27(2022), 3, Artikel-ID 690, Seite 1-13
DOI: 10.3390/molecules27030690
- Fresnais, Margaux: Approaching sites of action of temozolomide for pharmacological and clinical studies in glioblastoma / Margaux Fresnais, Sevin Turcan, Dirk Theile, Johannes Ungermann, Yasmin Abou Zeed, Joshua Raoul Lind… , 2022. - 27 S.
In: Biomedicines, ISSN 2227-9059. 10(2022), 1, Artikel-ID 10010001, Seite 1-27
DOI: 10.3390/biomedicines10010001
- Aklillu, Eleni: Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients / Eleni Aklillu, Alimuddin Zumla, Abiy Habtewold, Wondwossen Amogne, Eyasu Makonnen, Getnet Yimer, Jür… , August 2021. - 15 S.
In: British journal of pharmacology, ISSN 1476-5381. 178(2021), 16 vom: Aug., Seite 3294-3308
DOI: 10.1111/bph.15309
- Sauter, Max: Intact plasma quantification of the large therapeutic lipopeptide bulevirtide / Max Sauter, Antje Blank, Felicitas Stoll, Natalie Lutz, Walter E. Haefeli, Jürgen Burhenne, 20 May 2021. - 10 S.
In: Analytical and bioanalytical chemistry, ISSN 1618-2650. 413(2021), 22, Seite 5645-5654
DOI: 10.1007/s00216-021-03384-7
- Huppertz, Andrea: Differential effect of a continental breakfast on tacrolimus formulations with different release characteristics / Andrea Huppertz, Johanna Bollmann, Rouven Behnisch, Thomas Bruckner, Markus Zorn, Jürgen Burhenne, W… , 2021. - 9 S. : Illustrationen
In: Clinical pharmacology in drug development, ISSN 2160-7648. 10(2021), 8, Seite 899-907
DOI: 10.1002/cpdd.924
- Fresnais, Margaux: Desorption/ionization-MS methods for drug quantification in biological matrices and their validation following regulatory guidance / Margaux Fresnais, Jürgen Burhenne, Walter E. Haefeli, and Rémi Longuespée, April 29, 2021. - 12 S.
In: Analytical chemistry, ISSN 1520-6882. 93(2021), 19, Seite 7152-7163
DOI: 10.1021/acs.analchem.1c00647
- Longuespée, Rémi: Approaching sites of action of drugs in clinical pharmacology : New analytical options and their challenges / Rémi Longuespée, Dirk Theile, Margaux Fresnais, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, 2021. - 17 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 87(2021), 3, Seite 858-874
DOI: 10.1111/bcp.14543
- Grass, Jana: Absolute bioavailability of microdosed midazolam after buccal administration is dependent on buccal exposure time / Jana Grass, Peter Rose, Jürgen Burhenne, Antje Blank, Walter Emil Haefeli, and Gerd Mikus, 2021. - 8 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 61(2021), 4, Seite 472-479
DOI: 10.1002/jcph.1751
- Wass, Maxi: A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy / Maxi Wass, Stefanie Göllner, Birgit Besenbeck, Richard F. Schlenk, Petra Mundmann, Joachim R. Göther… , 2021. - 11 S. : Diagramme, Illustrationen
In: Leukemia, ISSN 1476-5551. 35(2021), 3, Seite 701-711
DOI: 10.1038/s41375-020-0892-z
- Benzel, Julia: Investigating the central nervous system disposition of actinomycin D : implementation and evaluation of cerebral microdialysis and brain tissue measurements supported by UPLC-MS/MS quantification / Julia Benzel, Gzona Bajraktari-Sylejmani, Philipp Uhl, Abigail Davis, Sreenath Nair, Stefan M. Pfist… , 17 September 2021. - 16 S.
In: Pharmaceutics, ISSN 1999-4923. 13(2021), 9, special issue, Artikel-ID 1498, Seite 1-16
DOI: 10.3390/pharmaceutics13091498
- Mahmoudi, Mazyar: Application of microdosed intravenous omeprazole to determine hepatic CYP2C19 activity / Mazyar Mahmoudi, Kathrin I. Foerster, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, and Walter E. Haef… , 2021. - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 61(2021), 6, Seite 789-798
DOI: 10.1002/jcph.1789
- Linde, Teresa von: Rapid and sensitive quantification of intracellular glycyl-sarcosine for semi-high-throughput screening for inhibitors of PEPT-1 / Teresa von Linde, Gzona Bajraktari-Sylejmani, Walter E. Haefeli, Jürgen Burhenne, Johanna Weiss and … , 3 July 2021. - 12 S.
In: Pharmaceutics, ISSN 1999-4923. 13(2021), 7, Artikel-ID 1019, Seite 1-12
DOI: 10.3390/pharmaceutics13071019
- Hohmann, Nicolas: Pharmacoenhancement of low crizotinib plasma concentrations in patients with anaplastic lymphoma kinase-positive non-small cell lung cancer using the CYP3A inhibitor cobicistat / Nicolas Hohmann, Farastuk Bozorgmehr, Petros Christopoulos, Gerd Mikus, Antje Blank, Jürgen Burhenne… , 2021. - 5 S.
In: Clinical and translational science, ISSN 1752-8062. 14(2021), 2, Seite 487-491
DOI: 10.1111/cts.12921
- Sauter, Max: Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS / Max Sauter, Kathrin I. Foerster, Julia Benzel, Stefan Pfister, Kristian W. Pajtler, Walter E. Haefel… , 20 May 2021. - 6 S.
In: Journal of chromatography, ISSN 1873-376X. 1176(2021), Artikel-ID 122781, Seite 1-6
DOI: 10.1016/j.jchromb.2021.122781
- Fresnais, Margaux: Rapid MALDI-MS assays for drug quantification in biological matrices : lessons learned, new developments, and future perspectives / Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W. … , 26 February 2021. - 19 S.
In: Molecules, ISSN 1420-3049. 26(2021), 5, Artikel-ID 1281, Seite 1-19
DOI: 10.3390/molecules26051281
- Sauter, Max: Application of triple quadrupole tandem mass spectrometry to the bioanalysis of collision-induced dissociation-resistant cyclic peptides : ultra-sensitive quantification of the somatostatin-analog pasireotide utilizing UHPLC-MS/MS / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 2021
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 194(2021) Artikel-Nummer 113728, 7 Seiten
DOI: 10.1016/j.jpba.2020.113728
- Mikus, Gerd: Application of a microdosed cocktail of 3 oral factor Xa inhibitors to study drug-drug interactions with different perpetrator drugs / Gerd Mikus, Kathrin I. Foerster, Marlene Schaumaeker, Marie-Louise Lehmann, Jürgen Burhenne, Walter … , 2020. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 86(2020), 8, Seite 1632-1641
DOI: 10.1111/bcp.14277
- Sauter, Max: New insights into the pharmacokinetics of vancomycin after oral and intravenous administration : an investigation in beagle dogs / Max Sauter, Philipp Uhl, Andreas D. Meid, Gerd Mikus, Jürgen Burhenne, Walter E. Haefeli, 20 March 2020. - 5 S.
In: Journal of pharmaceutical sciences, ISSN 1520-6017. 109(2020), 6, Seite 2090-2094
DOI: 10.1016/j.xphs.2020.03.012
- Sauter, Max: An underestimated factor : the extent of cross-reactions modifying APIs in surface-modified liposomal preparations caused by comprised activated lipids / Max Sauter, Jürgen Burhenne, Walter E. Haefeli and Philipp Uhl, 27 September 2020
In: Molecules, ISSN 1420-3049. 25(2020,19) Artikel-Nummer 4436, 11 Seiten
DOI: 10.3390/molecules25194436
- Fresnais, Margaux: Development and validation of an LC-MS-based quantification assay for new therapeutic antibodies : application to a novel therapy against herpes simplex virus / Margaux Fresnais, Rémi Longuespée, Max Sauter, Torsten Schaller, Michaela Arndt, Jürgen Krauss, Antj… , September 16, 2020. - 11 S.
In: ACS omega, ISSN 2470-1343. 5(2020), 38, Seite 24329-24339
DOI: 10.1021/acsomega.0c02547
- Fresnais, Margaux: Rapid and sensitive quantification of osimertinib in human plasma using a fully validated MALDI-IM-MS/MS assay / Margaux Fresnais, André Roth, Kathrin I. Foerster, Dirk Jäger, Stefan M. Pfister, Walter E. Haefeli,… , 14 July 2020. - 18 S.
In: Cancers, ISSN 2072-6694. 12(2020,7) Artikel-Nummer 1897, 18 Seiten
DOI: 10.3390/cancers12071897
- Jedamzik, Julia: No alteration of Cyp3A4 activity after major hepatectomy in the early postoperative period : a prospective before-after study / J. Jedamzik, J. Mühlbacher, F. Fitschek, C. Schwarz, J. Burhenne, U. Asenbaum, K. Kaczirek, G. Mikus, 12 May 2020. - 5 S.
In: International journal of surgery, ISSN 1743-9159. 79(2020), Seite 131-135
DOI: 10.1016/j.ijsu.2020.05.010
- Sadik, Ahmed: IL4I1 is a metabolic immune checkpoint that activates the AHR and promotes tumor progression / Ahmed Sadik, Luis F. Somarribas Patterson, Selcen Öztürk, Soumya R. Mohapatra, Verena Panitz, Philip… , August 19, 2020. - 54 S.
In: Cell, ISSN 1097-4172. 182(2020), 5, Seite 1252-1270.e34
DOI: 10.1016/j.cell.2020.07.038
- Burhenne, Jürgen: Safety and activity of the combination of ceritinib and dasatinib in osteosarcoma / Olaf Beck, Claudia Paret, Alexandra Russo, Jürgen Burhenne, Margaux Fresnais, Kevin Steimel, Larissa… , 26 March 2020. - 15 S.
In: Cancers, ISSN 2072-6694. 12(2020,4) Artikel-Nummer 793, 15 Seiten
DOI: 10.3390/cancers12040793
- Sauter, Max: Ultra-sensitive bioanalysis of the therapeutic peptide exenatide for accurate pharmacokinetic analyses at effective plasma concentrations utilizing UPLC-MS/MS / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 22 February 2020. - 7 S.
In: Journal of pharmaceutical analysis, ISSN 2214-0883. 10(2020), 3, Seite 233-239
DOI: 10.1016/j.jpha.2020.02.008
- Stoll, Felicitas E.: Impact of pantoprazole on absorption and disposition of hydroxychloroquine, a drug used in Corona Virus Disease-19 (Covid-19) : A structured summary of a study protocol for a randomised controlled trial / Felicitas Stoll, Antje Blank, Gerd Mikus, David Czock, Kathrin I. Foerster, Simon Hermann, Katja Häu… , 29 June 2020. - 2 S.
In: Trials, ISSN 1468-6694. 21(2020), Artikel-ID 584, Seite 1-2
DOI: 10.1186/s13063-020-04476-y
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In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 186(2020) Artikel-Nummer 113276, 6 Seiten
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- Sauter, Max: Post-extraction disulfide bond cleavage for MS/MS quantification of collision-induced dissociation-resistant cystine-cyclized peptides and its application to the ultra-sensitive UPLC-MS/MS bioanalysis of octreotide in plasma / Max Sauter, Philipp Uhl, Jürgen Burhenne, Walter E. Haefeli, 10 April 2020. - 8 S.
In: Analytica chimica acta, ISSN 1873-4324. 1114(2020), Seite 42-49
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London: Future Science, 2019. - 1 Online-Ressource (12 Seiten)
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In: Clinical epigenetics, ISSN 1868-7083. 11(2019) Artikel-Nummer 188, 15 Seiten
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In: Clinical pharmacokinetics, ISSN 1179-1926. 59(2020), 5, Seite 643-654
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In: BMC pharmacology & toxicology, ISSN 2050-6511. 20(2019,1) Artikel-Nummer 53, 6 Seiten
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- Fresnais, Margaux: Advances in clinical pharmacology : rapid detection of small molecules in solid samples at atmospheric pressure using desorption electrospray ionization / Margaux Fresnais, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée, 2019. - 2 S.
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In: Analytical methods, ISSN 1759-9679. 11(2019), 47, Seite 5976-5983
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In: International journal of molecular sciences, ISSN 1422-0067. 20(2019,17) Artikel-Nummer 4267, Seite 1-19, 19 Seiten
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In: Scientific reports, ISSN 2045-2322. 9(2019) Artikel-Nummer 14635, 6 Seiten
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In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 125(2019), 2, Seite 117-122
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In: Bioanalysis, ISSN 1757-6199. 11(2019), 9, Seite 887-898
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In: Palliative medicine, ISSN 1477-030X. 33(2019), 7, Seite 850-855
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In: British journal of clinical pharmacology, ISSN 1365-2125. 85(2019), 7, Seite 1528-1537
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In: European journal of pharmaceutical sciences, ISSN 1879-0720. 135(2019), Seite 77-82
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In: Analytical chemistry, ISSN 1520-6882. 90(2018), 15, Seite 9395-9402
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- Paleari, Laura: High accumulation of metformin in colonic tissue of subjects with diabetes or the metabolic syndrome / Laura Paleari, Jürgen Burhenne, Johanna Weiss, Sebastian Foersch, Wilfried Roth, Andrea Parodi, Mich… , [2018]. - 3 S.
In: Gastroenterology, ISSN 1528-0012. 154(2018), 5, Seite 1543-1545
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In: British journal of clinical pharmacology, ISSN 1365-2125. 84(2018), 12, Seite 2903-2913
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In: Journal of palliative medicine, ISSN 1557-7740. 21(2018), 5, Seite 686-688
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In: British journal of clinical pharmacology, ISSN 1365-2125. 84(2018), 8, Seite 1738-1747
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In: Scientific reports, ISSN 2045-2322. 8(2018) Artikel-Nummer 16316, 12 Seiten
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In: Clinical infectious diseases, ISSN 1537-6591. 66(2018), 10, Seite 1644-1646
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In: European journal of clinical pharmacology, ISSN 1432-1041. 74(2018), 11, Seite 1405-1415
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In: British journal of clinical pharmacology, ISSN 1365-2125. 85(2019), 2, Seite 458-459
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- Schäfer, Julia: Elucidating the beneficial effects of melphalan, adriamycin, and corticoids in combination with bortezomib against multiple myeloma in vitro / Julia Schäfer, Jürgen Burhenne, Johanna Weiss, Dirk Theile, 2019. - 6 S.
In: Naunyn-Schmiedeberg's archives of pharmacology, ISSN 1432-1912. 392(2019), 4, Seite 461-466
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- Blank, Antje: The NTCP-inhibitor Myrcludex B : effects on bile acid disposition and tenofovir pharmacokinetics / A Blank, A Eidam, M Haag, N Hohmann, J Burhenne, M Schwab, SFJ van de Graaf, MR Meyer, HH Maurer, K … , 2018. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 103(2018), 2, Seite 341-348
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In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 143(2017), Seite 291-298
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In: Journal of clinical pharmacology, ISSN 1552-4604. 57(2017), 7, Seite 899-905
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In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 61(2017,8) Artikel-Nummer e00207-17, 13 Seiten
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- Schäfer, Julia: Cellular effect and efficacy of carfilzomib depends on cellular net concentration gradient / Julia Schäfer, Lukas Welti, Anja Seckinger, Jürgen Burhenne, Dirk Theile, Johanna Weiss, 12 May 2017. - 9 S.
In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 80(2017), 1, Seite 71-79
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In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 151(2018), Seite 151-158
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In: British journal of clinical pharmacology, ISSN 1365-2125. 83(2017), 9, S. 1954-1965
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- Harnoß, Jonathan M.: Prolyl hydroxylase inhibition enhances liver regeneration without induction of tumor growth / Jonathan M. Harnoss, MD, Lisa K. Platzer, Juergen Burhenne, PhD, Praveen Radhakrishnan, MSc, Jun Cai… , April 1, 2017. - 10 S.
In: Annals of surgery, ISSN 1528-1140. 265(2017), 4, Seite 782-791
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In: Clinical infectious diseases, ISSN 1537-6591. 65(2017), 6, Seite 1033-1036
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- Clemens, Jannick: Bortezomib, carfilzomib and ixazomib do not mediate relevant transporter‑based drug‑drug interactions / Jannick Clemens, Lukas Welti, Julia Schäfer, Anja Seckinger, Jürgen Burhenne, Dirk Theile and Johann… . - 8 S.
In: Oncology letters, ISSN 1792-1082. 14(2017), 3, S. 3185-3192
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In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 80(2017), 2, Seite 433-439
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In: Respiration, ISSN 1423-0356. 94(2017), 1, Seite 26-37
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In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 142(2017), S. 84-90
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- Bajraktari-Sylejmani, Gzona: Cyclic guanosine monophosphate modulates accumulation of phosphodiesterase 5 inhibitors in human platelets / Gzona Bajraktari, Jürgen Burhenne, Peter Bugert, Walter Emil Haefeli, Johanna Weiss, 1 December 2017. - 10 S.
In: Biochemical pharmacology, ISSN 1873-2968. 145(2017), Seite 54-63
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- Moj, Daniel: A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model of the histone deacetylase (HDAC) inhibitor vorinostat for pediatric and adult patients and its application for dose specification / Daniel Moj, Hannah Britz, Jürgen Burhenne, Clinton F. Stewart, Gerlinde Egerer, Walter E. Haefeli, T… . - 14 S.
In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 80(2017), 5, S. 1013–1026
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- Bajraktari-Sylejmani, Gzona: The phosphodiesterase inhibitors sildenafil and tadalafil accumulate inside platelets in the presence of cyclic guanosine monophosphate / Gzona Bajraktari, Jürgen Burhenne, Walter E. Haefeli and Johanna Weiss, 10 October 2017
In: BMC pharmacology & toxicology, ISSN 2050-6511. 18(2017, Supplement 1) Artikel-Nummer A32, 1 Seite
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- Nylén, Hanna: Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency : a prospective cohort study / Hanna Nylén, PhD, Abiy Habtewold, PhD, Eyasu Makonnen, PhD, Getnet Yimer, PhD, Leif Bertilsson, PhD,… , 2016 Aug 26
In: Medicine, ISSN 1536-5964. 95(2016,34) Artikel-Nummer e4631, 10 Seiten
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- Weinheimer, Manuel: The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers : an in vitro and in vivo comparison / Manuel Weinheimer, Gert Fricker, Jürgen Burhenne, Patricia Mylius, Rolf Schubert, 2017. - 10 S.
In: European journal of pharmaceutical sciences, ISSN 1879-0720. 108(2017), Seite 13-22
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- Habtewold, Abiy: Long-term effect of rifampicin-based Anti-TB regimen coadministration on the pharmacokinetic parameters of efavirenz and 8-Hydroxy-Efavirenz in ethiopian patients / Abiy Habtewold, PhD, Eleni Aklillu, PhD, Eyasu Makonnen, PhD, Wondwossen Amogne, MD, PhD, Getnet Yim… . - 12 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 56(2016), 12, S. 1538-1549
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- Dettmer, Susan: Proteasome inhibition correlates with intracellular bortezomib concentrations but not with antiproliferative effects after bolus treatment in myeloma cell lines / Susan Dettmer, Dirk Theile, Julia Schäfer, Anja Seckinger, Jürgen Burhenne, Johanna Weiss. - 11 S.
In: Naunyn-Schmiedeberg's archives of pharmacology, ISSN 1432-1912. 389(2016), 10, S. 1091-1101
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In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 130(2016), Supplement C, Seite 231-243
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In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 71(2016), 8, Seite 2241-2247
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In: Clinical pharmacokinetics, ISSN 1179-1926. 55(2016), 12, S. 1535-1545
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- Schmitt, Thomas: Vorinostat in refractory soft tissue sarcomas : results of a multi-centre phase II trial of the German Soft Tissue Sarcoma and Bone Tumour Working Group (AIO) / Thomas Schmitt, Regine Mayer-Steinacker, Frank Mayer, Viktor Grünwald, Jochen Schütte, Jörg T. Hartm… , September 2016. - 9 S.
In: European journal of cancer, ISSN 1879-0852. 64(2016), Seite 74-82
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- Habtewold, Abiy: Is there a need to increase the dose of efavirenz during concomitant rifampicin-based antituberculosis therapy in sub-Saharan Africa? : the HIV-TB pharmagene study / Abiy Habtewold, Eyasu Makonnen, Wondwossen Amogne, Getnet Yimer, Getachew Aderaye, Leif Bertilsson, … , 1 Apr 2015. - 17 S.
In: Pharmacogenomics, ISSN 1744-8042. 16(2015), 10, Seite 1047-1064
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In: Glia, ISSN 1098-1136. 63(2015), 10, Seite 1850-1859
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In: Analytical chemistry, ISSN 1520-6882. 87(2015), 24, Seite 12112-12120
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In: Cancer chemotherapy and pharmacology, ISSN 1432-0843. 75(2015), 2, Seite 281-291
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In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 69(2014), 12, Seite 3311-3319
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- Markert, Christoph: Influence of St. John’s wort on the steadystate pharmacokinetics and metabolism of bosentan / Christoph Markert, Prisca Ngui, Regina Hellwig, Theresia Wirsching, Ida Maria Kastner, Klaus-Dieter … , 2014. - 9 S.
In: International journal of clinical pharmacology and therapeutics. 52(2014), 04, Seite 328-336
DOI: 10.5414/CP202048
- Hohmann, Nicolas: Midazolam microdose to determine systemic and pre-systemic metabolic CYP3A activity in humans / Nicolas Hohmann, Franziska Kocheise, Alexandra Carls, Jürgen Burhenne, Walter E. Haefeli, Gerd Mikus, 2015. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 79(2015), 2, Seite 278-285
DOI: 10.1111/bcp.12502
- Markert, Christoph: Lack of a clinically significant interaction of grapefruit juice with ambrisentan and bosentan in healthy adults / Christoph Markert, Theresia Wirsching, Regina Hellwig, Jürgen Burhenne, Johanna Weiss, Klaus-Dieter … , 2014. - 8 S.
In: International journal of clinical pharmacology and therapeutics. 52(2014), 11, Seite 957-964
DOI: 10.5414/CP202164
- Liu, Lu: Quantification of vorinostat and its main metabolites in plasma and intracellular vorinostat in PBMCs by liquid chromatography coupled to tandem mass spectrometry and its relation to histone deacetylase activity in human blood / Lu Liu, Jan-Christoph Detering, Till Milde, Walter Emil Haefeli, Olaf Witt, Jürgen Burhenne, 18 February 2014. - 10 S.
In: Journal of chromatography, ISSN 1873-376X. 964(2014), Seite 212-221
DOI: 10.1016/j.jchromb.2014.02.014
- Dettmer, Susan: Fetal calf sera can distort cell-based luminescent proteasome assays through heat-resistant chymotrypsin-like activity / Susan Dettmer, Dirk Theile, Anja Seckinger, Jürgen Burhenne, Johanna Weiss, 2015. - 3 S.
In: Analytical biochemistry, ISSN 1096-0309. 471(2015), Seite 23-25
DOI: 10.1016/j.ab.2014.10.019
- Eichbaum, Christine: Pre-systemic elimination of tilidine : localization and consequences for the formation of the active metabolite nortilidine / Christine Eichbaum, Kristin Mathes, Jürgen Burhenne, Christoph Markert, Antje Blank and Gerd Mikus, 2015. - 5 S.
In: Basic & clinical pharmacology & toxicology, ISSN 1742-7843. 116(2015), 2, Seite 129-133
DOI: 10.1111/bcpt.12328
- Clemens, Jannick: Stability of the proteasome inhibitor bortezomib in cell based assays determined by ultra-high performance liquid chromatography coupled to tandem mass spectrometry / Jannick Clemens, Magdalena Longo, Anja Seckinger, Dirk Hose, Walter Emil Haefeli, Johanna Weiss, Jür… , 6 June 2014. - 11 S.
In: Journal of chromatography, ISSN 1873-3778. 1345(2014), Seite 128-138
DOI: 10.1016/j.chroma.2014.04.024
- Schmitt, Thomas: Aprepitant, Granisetron, and Dexamethasone for prevention of chemotherapy-induced nausea and vomiting after high-dose Melphalan in autologous transplantation for multiple myeloma : results of a randomized, placebo-controlled phase III trial / Thomas Schmitt, Hartmut Goldschmidt, Kai Neben, Anja Freiberger, Johannes Hüsing, Martina Gronkowski… , October 20 2014. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 32(2014), 30, Seite 3413-3420
DOI: 10.1200/JCO.2013.55.0095
- Carls, Alexandra: Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity / Alexandra Carls, Julia Jedamzik, Lukas Witt, Nicolas Hohmann, Juergen Burhenne, Gerd Mikus. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 78(2014), 6, S. 1433-1440
DOI: 10.1111/bcp.12497
- Markert, Christoph: CYP2C9 polymorphism is not a major determinant of bosentan exposure in healthy volunteers / C. Markert, J. Burhenne, J. Weiss, G. Mikus and W. E. Haefeli. - 2 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 95(2014), 3, S. 250-251
DOI: 10.1038/clpt.2013.188
- Markert, Christoph: Clarithromycin substantially increases steady-state bosentan exposure in healthy volunteers / Christoph Markert, Yvonne Schweizer, Regina Hellwig, Theresia Wirsching, Klaus-Dieter Riedel, Juerge… , 2014. - 8 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 77(2014), 1, Seite 141-148
DOI: 10.1111/bcp.12177
- Carls, Alexandra: Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease : two case reports / Carls, Alexandra; Winter, Julia; Enderle, Yeliz; Burhenne, Jürgen; Gorenflo, Matthias; Haefeli, Walt… , 2014. - 5 S.
In: Journal of medical case reports, ISSN 1752-1947. 8(2014), Seite 1-5
DOI: 10.1186/1752-1947-8-171
- Albarmawi, Albader: CYP3A activity in severe liver cirrhosis correlates with Child-Pugh and model for end-stage liver disease (MELD) scores / Albarmawi, Albader; Czock, David; Gauss, Annika; Ehehalt, Robert; Bermejo, Justo Lorenzo; Burhenne, … , 2014. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 77(2014), 1, Seite 160-169
DOI: 10.1111/bcp.12182
- Stoll, Felicitas E.: Reduced exposure variability of the CYP3A substrate simvastatin by dose individualization to CYP3A activity / Felicitas Stoll, Jürgen Burhenne, Berthold Lausecker, Johanna Weiss, Torben Thomsen, Walter Emil Hae… , 2013. - 6 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 53(2013), 11, Seite 1199-1204
DOI: 10.1002/jcph.161
- Ngaimisi, Eliford: Importance of ethnicity, CYP2B6 and ABCB1 genotype for efavirenz pharmacokinetics and treatment outcomes : a parallel-group prospective cohort study in two sub-Saharan Africa populations / Eliford Ngaimisi, Abiy Habtewold, Omary Minzi, Eyasu Makonnen, Sabina Mugusi, Wondwossen Amogne, Get… , July 5, 2013. - 13 S.
In: PLOS ONE, ISSN 1932-6203. 8(2013), 7, Artikel-ID e67946, Seite 1-13
DOI: 10.1371/journal.pone.0067946
- Zembruski, Nadine Cécile Luise: Liposomal sphingomyelin influences the cellular lipid profile of human lymphoblastic leukemia cells without effect on P-glycoprotein activity / Nadine C.L. Zembruski, Chi D.L. Nguyen, Dirk Theile, Ramadan M.M. Ali, Melanie Herzog, Götz Hofhaus,… , 19 February 2013. - 15 S.
In: Molecular pharmaceutics, ISSN 1543-8392. 10(2013), 3, Seite 1020-1034
DOI: 10.1021/mp300485j
- Markert, Christoph: Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1 / Christoph Markert, Regina Hellwig, Jürgen Burhenne, Michael Marcus Hoffmann, Johanna Weiss, Gerd Mik… , 9 June 2013. - 9 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 10, Seite 1785-1793
DOI: 10.1007/s00228-013-1529-1
- Halama, Birte: A nanogram dose of the CYP3A probe substrate midazolam to evaluate drug interactions / B Halama, N Hohmann, J Burhenne, J Weiss, G Mikus and WE Haefeli, 20 March 2013. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 93(2013), 6, Seite 564-571
DOI: 10.1038/clpt.2013.27
- Geist, Marcus Julian Peter: Steady-state pharmacokinetics and metabolism of voriconazole in patients / Marcus J.P. Geist, Gerlinde Egerer, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss and Gerd Mik… , 13 June 2013. - 8 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 68(2013), 11, Seite 2592-2599
DOI: 10.1093/jac/dkt229
- Grün, Barbara: Trimethoprim-metformin interaction and its genetic modulation by OCT2 and MATE1 transporters / Barbara Grün, Michael K. Kiessling, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss, Geraldine R… , 11 January 2013. - 10 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 76(2013), 5, Seite 787-796
DOI: 10.1111/bcp.12079
- Eichbaum, Christine: Concentration effect relationship of CYP3A inhibition by ritonavir in humans / Christine Eichbaum, Marianna Cortese, Antje Blank, Jürgen Burhenne, Gerd Mikus, 9 June 2013. - 6 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 10, Seite 1795-1800
DOI: 10.1007/s00228-013-1530-8
- Weiß, Johanna: Influence of sildenafil and tadalafil on the enzyme- and transporter-inducing effects of bosentan and ambrisentan in LS180 cells / Johanna Weiss, Dirk Theile, Adriana Spalwisz, Jürgen Burhenne, Klaus-Dieter Riedel, Walter Emil Haef… , 2013. - 9 S.
In: Biochemical pharmacology, ISSN 1873-2968. 85(2013), 2, Seite 265-273
DOI: 10.1016/j.bcp.2012.11.020
- Habtewold, Abiy: Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients / A Habtewold, W Amogne, E Makonnen, G Yimer, H Nylén, K-D Riedel, G Aderaye, L Bertilsson, J Burhenne… , 2013. - 6 S.
In: The pharmacogenomics journal, ISSN 1473-1150. 13(2013), 6, Seite 484-489
DOI: 10.1038/tpj.2012.46
- Mugusi, Sabina: Liver enzyme abnormalities and associated risk factors in HIV patients on Efavirenz-Based HAART with or without tuberculosis co-infection in Tanzania / Sabina Mugusi, Eliford Ngaimisi, Mohamed Janabi, Omary Minzi, Muhammad Bakari, Klaus-Dieter Riedel, … , July 11, 2012. - 9 S.
In: PLOS ONE, ISSN 1932-6203. 7(2012,7), Artikel-Nr. e40180, 9 Seiten
DOI: 10.1371/journal.pone.0040180
- Keubler, Anja: Drug interaction of efavirenz and midazolam : efavirenz activates the CYP3A-mediated midazolam 1′-Hydroxylation in vitro / Anja Keubler, Johanna Weiss, Walter E. Haefeli, Gerd Mikus, Jürgen Burhenne, May 16, 2012. - 5 S.
In: Drug metabolism and disposition, ISSN 1521-009X. 40(2012), 6, Seite 1178-1182
DOI: 10.1124/dmd.111.043844
- Burhenne, Jürgen: Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1′-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry / Jürgen Burhenne, Birte Halama, Monika Maurer, Klaus-Dieter Riedel, Nicolas Hohmann, Gerd Mikus, Walt… , 15 January 2012. - 12 S.
In: Analytical and bioanalytical chemistry, ISSN 1618-2650. 402(2012), 7, Seite 2439-2450
DOI: 10.1007/s00216-011-5675-y
- Burhenne, Jürgen: Evaluation of the influence of formulation, food intake and species on voriconazole plasma concentration in birds / J. Burhenne and A. Scope, 2012. - 6 S.
In: Veterinary medicine Austria. 99(2012), Seite 157-162
- Fuchs, Ines Verena: Effect of the CYP3A inhibitor ketoconazole on the PXR-mediated induction of CYP3A activity / Ines Fuchs, Verena Hafner-Blumenstiel, Christoph Markert, Jürgen Burhenne, Johanna Weiss, Walter Emi… . - 7 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 69(2013), 3, S. 507-513
DOI: 10.1007/s00228-012-1388-1
- Ali, Ramadan Mahmoud Mohamed: Quantification of retinoid concentrations in human serum and brain tumor tissues / Ramadan Ali, Benito Campos, Gerhard Dyckhoff, Walter E. Haefeli, Christel Herold-Mende, Jürgen Burhe… . - 10 S.
In: Analytica chimica acta, ISSN 1873-4324. 725(2012), S. 57-66
DOI: 10.1016/j.aca.2012.03.003
- Theile, Dirk: Cellular pharmacokinetic/pharmacodynamic relationship of platinum cytostatics in head and neck squamous cell carcinoma evaluated by liquid chromatography coupled to tandem mass spectrometry / Dirk Theile, Jan-Christoph Detering, Christel Herold-Mende, Gerhard Dyckhoff, Walter E. Haefeli, Joh… . - 8 S.
In: The journal of pharmacology and experimental therapeutics, ISSN 1521-0103. 341(2012), 1, S. 51-58
DOI: 10.1124/jpet.111.189621
- Burhenne, Jürgen: Quantification of femtomolar concentrations of the CYP3A substrate midazolam and its main metabolite 1'-hydroxymidazolam in human plasma using ultra performance liquid chromatography coupled to tandem mass spectrometry / Jürgen Burhenne; Birte Halama; Monika Maurer; Klaus-Dieter Riedel; Nicolas Hohmann; Gerd Mikus; Wal… , 2012. - 12 S.
In: Analytical & bioanalytical chemistry, ISSN 1618-2642. 402(2012), 7, Seite 2439-2450
- Yin, Jun: Sildenafil preserves lung endothelial function and prevents pulmonary vascular remodeling in a rat model of diastolic heart failure / Jun Yin, Marian Kukucka, Julia Hoffmann, Anja Sterner-Kock, Juergen Burhenne, Walter E. Haefeli, Her… , 7 Jan 2011. - 9 S.
In: Circulation, ISSN 1941-3297. 4(2011), 2, Seite 198-206
DOI: 10.1161/CIRCHEARTFAILURE.110.957050
- Yimer, Getnet: Pharmacogenetic & pharmacokinetic biomarker for efavirenz based ARV and rifampicin based anti-TB drug induced liver injury in TB-HIV infected patients / Getnet Yimer, Nobuhisa Ueda, Abiy Habtewold, Wondwossen Amogne, Akira Suda, Klaus-Dieter Riedel, Jür… , December 6, 2011. - 9 S.
In: PLOS ONE, ISSN 1932-6203. 6(2011), 12, Artikel-ID e27810, Seite 1-9
DOI: 10.1371/journal.pone.0027810
- Ngaimisi, Eliford: Effect of rifampicin and CYP2B6 genotype on long-term efavirenz autoinduction and plasma exposure in HIV patients with or without tuberculosis / E Ngaimisi, S Mugusi, O Minzi, P Sasi, K-D Riedel, A Suda, N Ueda, M Janabi, F Mugusi, WE Haefeli, L… , 03 August 2011. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 90(2011), 3 vom: Sept., Seite 406-413
DOI: 10.1038/clpt.2011.129
- Motorin, Yuri: Expanding the chemical scope of RNA : methyltransferases to site-specific alkynylation of RNA for click labeling / Yuri Motorin, Jürgen Burhenne, Roman Teimer, Kaloian Koynov, Sophie Willnow, Elmar Weinhold and Mark… , 2011. - 10 S.
In: Nucleic acids research, ISSN 1362-4962. 39(2011), 5, Seite 1943-1952
DOI: 10.1093/nar/gkq825
- Hassan, Arwa: Modulators of very low voriconazole concentrations in routine therapeutic drug monitoring / Arwa Hassan, Jürgen Burhenne, Klaus-Dieter Riedel, Johanna Weiss, Gerd Mikus, Walter E. Haefeli, Dav… , [February 2011]. - 8 S.
In: Therapeutic drug monitoring, ISSN 1536-3694. 33(2011), 1, Seite 86-93
DOI: 10.1097/FTD.0b013e31820530cd
- Kaiser, Stefanie: A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA / Stefanie Kellner, Salifu Seidu-Larry, Jürgen Burhenne, Yuri Motorin and Mark Helm, 6 June 2011. - 13 S.
In: Nucleic acids research, ISSN 1362-4962. 39(2011), 16, Seite 7348-7360
DOI: 10.1093/nar/gkr449
- Habtewold, Abiy: Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients / Abiy Habtewold, Wondwossen Amogne, Eyasu Makonnen, Getnet Yimer, Klaus-Dieter Riedel, Nobuhisa Ueda,… , October 2011. - 12 S.
In: The journal of antimicrobial chemotherapy, ISSN 1460-2091. 66(2011), 10, Seite 2350-2361
DOI: 10.1093/jac/dkr304
- Katzenmaier, Stephanie Katharina: Determining the time course of CYP3A inhibition by potent reversible and irreversible CYP3A inhibitors using a limited sampling strategy / S Katzenmaier, C Markert, K-D Riedel, J Burhenne, WE Haefeli and G Mikus, 21 September 2011. - 8 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 90(2011), 5, Seite 666-673
DOI: 10.1038/clpt.2011.164
- Campos, Benito: Aberrant expression of retinoic acid signaling molecules influences patient survival in astrocytic gliomas / Benito Campos, Franz-Simon Centner, Justo Lorenzo Bermejo, Ramadan Ali, Katharina Dorsch, Feng Wan, … , 20 April 2011. - 12 S.
In: The American journal of pathology, ISSN 1525-2191. 178(2011), 5, Seite 1953-1964
DOI: 10.1016/j.ajpath.2011.01.051
- Rudofsky, Leonie: Daily honey consumption does not change CYP3A activity in humans / Leonie Fetzner, Jürgen Burhenne, PhD, Johanna Weiss, PhD, Michael Völker, Matthias Unger, PhD, Gerd … , 2011. - 10 S.
In: Journal of clinical pharmacology, ISSN 1552-4604. 51(2011), 8, Seite 1223-1232
DOI: 10.1177/0091270010382022
- Yimer, Getnet: High plasma efavirenz level and CYP2B6*6 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia : a prospective cohort study / G. Yimer, W. Amogne, A. Habtewold, E. Makonnen, N. Ueda, A. Suda, A. Worku, W.E. Haefeli, J. Burhenn… . - 8 S.
In: The pharmacogenomics journal, ISSN 1473-1150. 12(2012), 6, S. 499-506
DOI: 10.1038/tpj.2011.34
- Hafner-Blumenstiel, Verena: Pharmacokinetics of sulfobutylether-beta-cyclodextrin and voriconazole in patients with end-stage renal failure during treatment with two hemodialysis systems and hemodiafiltration / Verena Hafner, David Czock, Jürgen Burhenne, Klaus-Dieter Riedel, Jürgen Bommer, Gerd Mikus, Christo… , 1 June 2010. - 7 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 54(2010), 6, Seite 2596-2602
DOI: 10.1128/aac.01540-09
- Hafner-Blumenstiel, Verena: Effect of simultaneous induction and inhibition of CYP3A by St John's wort and ritonavir on CYP3A activity / V Hafner, M Jäger, A-K Matthée, R Ding, J Burhenne, WE Haefeli and G Mikus, 2010. - 6 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 87(2010), 2, Seite 191-196
DOI: 10.1038/clpt.2009.206
- Burkhardt, Olaf: Sulphobutylether-β-cyclodextrin accumulation in critically ill patients with acute kidney injury treated with intravenous voriconazole under extended daily dialysis / Olaf Burkhardt, Simone Thon, Jürgen Burhenne, Tobias Welte, Jan T. Kielstein, 8 April 2010. - 2 S.
In: International journal of antimicrobial agents, ISSN 1872-7913. 36(2010), 1 vom: Juli, Seite 93-94
DOI: 10.1016/j.ijantimicag.2010.02.017
- Burhenne, Jürgen: No evidence for induction of ABC transporters in peripheral blood mononuclear cells in humans after 14 days of efavirenz treatment / Jürgen Burhenne, Anne-Kathrin Matthée, Ivana Pasáková, Claudia Röder, Tilman Heinrich, Walter Emil H… , 1 October 2010. - 7 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 54(2010), 10, Seite 4185-4191
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- Kaiser, Stefanie: Detection of RNA modifications / Stefanie Kellner, Jürgen Burhenne and Mark Helm, 01 Mar 2010. - 11 S.
In: RNA biology, ISSN 1555-8584. 7(2010), 2 vom: März/Apr., Seite 237-247
DOI: 10.4161/rna.7.2.11468
- Egerer, Gerlinde: The NK1 receptor antagonist aprepitant does not alter the pharmacokinetics of high-dose melphalan chemotherapy in patients with multiple myeloma / Gerlinde Egerer, Kathrin Eisenlohr, Martina Gronkowski, Juergen Burhenne, Klaus-Dieter Riedel & Gerd… , 30 August 2010. - 5 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 70(2010), 6 vom: Dez., Seite 903-907
DOI: 10.1111/j.1365-2125.2010.03792.x
- Bountogo, Mamadou: Efficacy of methylene blue monotherapy in semi-immune adults with uncomplicated falciparum malaria : a controlled trial in Burkina Faso / Mamadou Bountogo, Augustin Zoungrana, Boubacar Coulibaly, Christina Klose, Ulrich Mansmann, Frank P.… , 10 May 2010. - 5 S.
In: Tropical medicine & international health, ISSN 1365-3156. 15(2010), 6, Seite 713-717
DOI: 10.1111/j.1365-3156.2010.02526.x
- Josephson, Filip: CYP3A5 genotype has an impact on the metabolism of the HIV protease inhibitor saquinavir / F. Josephson, A. Allqvist, M. Janabi, J. Sayi, E. Aklillu, M. Jande, M. Mahindi, J. Burhenne, Y. Bot… , 28 February 2007. - 5 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 81(2007), 5, Seite 708-712
DOI: 10.1038/sj.clpt.6100117
- Kees, Frieder: Comparative bioavailability of the microemulsion formulation of cyclosporine (Neoral) with a generic dispersion formulation (Cicloral) in young healthy male volunteers / Kees, Frieder ; Bucher, Michael ; Schweda, Frank ; Gschaidmeier, Harald ; Burhenne, Juergen ; Mikus,… , 2006. - 9 S.
In: Therapeutic drug monitoring, ISSN 1536-3694. 28(2006), 3, Seite 312-320
DOI: 10.1097/01.ftd.0000211804.89440.74
- Geist, Marcus Julian Peter: Safety of voriconazole in a patient with CYP2C9*2/CYP2C9*2 genotype / Marcus J.P. Geist, Gerlinde Egerer, Jürgen Burhenne, Gerd Mikus, 2006. - 2 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 50(2006), 9, Seite 3227-3228
DOI: 10.1128/AAC.00551-06
- Mikus, Gerd: Potent cytochrome P450 2C19 genotype-related interaction between voriconazole and the cytochrome P450 3A4 inhibitor ritonavir / Gerd Mikus, Verena Schöwel, Magdalena Drzewinska, Jens Rengelshausen, Reinhard Ding, Klaus-Dieter Ri… , 19 August 2006. - 10 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 80(2006), 2, Seite 126-135
DOI: 10.1016/j.clpt.2006.04.004
- Ehrhardt, Manuela: Monitoring of lopinavir and ritonavir in peripheral blood mononuclear cells, plasma, and ultrafiltrate using a selective and highly sensitive LC/MS/MS assay / Manuela Ehrhardt, Marion Möck, Walter E. Haefeli, Gerd Mikus, Jürgen Burhenne, 2007. - 10 S.
In: Journal of chromatography, ISSN 1873-376X. 850(2007), 1, Seite 249-258
DOI: 10.1016/j.jchromb.2006.11.037
- Meissner, Peter: Safety of the methylene blue plus chloroquine combination in the treatment of uncomplicated falciparum malaria in young children of Burkina Faso [ISRCTN27290841] / Peter E. Meissner, Germain Mandi, Steffen Witte, Boubacar Coulibaly, Ulrich Mansmann, Jens Rengelsha… , 22 September 2005. - 9 S.
In: Malaria journal, ISSN 1475-2875. 4(2005), Artikel-ID 45
DOI: 10.1186/1475-2875-4-45
- Rengelshausen, Jens: Opposite effects of short-term and long-term St John's wort intake on voriconazole pharmacokinetics / Jens Rengelshausen, Maria Banfield, Klaus-Dieter Riedel, Jürgen Burhenne, Johanna Weiss, Torben Thom… , 25 July 2005. - 9 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 78(2005), 1, Seite 25-33
DOI: 10.1016/j.clpt.2005.01.024
- Streit, Michael: Cytochrome P450 enzyme-mediated drug metabolism at exposure to acute hypoxia (corresponding to an altitude of 4,500 m) / Michael Streit, Christoph Göggelmann, Christoph Dehnert, Jürgen Burhenne, Klaus-Dieter Riedel, Elmar… , 04 February 2005. - 8 S.
In: European journal of clinical pharmacology, ISSN 1432-1041. 61(2005), 1, Seite 39-46
DOI: 10.1007/s00228-004-0886-1
- Akoachere, Monique B.: In vitro assessment of methylene blue on chloroquine-sensitive and -resistant plasmodium falciparum strains reveals synergistic action with artemisinins / Monique Akoachere, Kathrin Buchholz, Elisabeth Fischer, Jürgen Burhenne, Walter E. Haefeli, R. Heine… , Nov. 2005. - 6 S.
In: Antimicrobial agents and chemotherapy, ISSN 1098-6596. 49(2005), 11, Seite 4592-4597
DOI: 10.1128/AAC.49.11.4592-4597.2005
- Borwitzky, Holger: Analysis of methylene blue in human urine by capillary electrophoresis / Holger Borwitzky, Walter E. Haefeli, Jürgen Burhenne, 22 September 2005. - 8 S.
In: Journal of chromatography, ISSN 1873-376X. 826(2005), 1/2, Seite 244-251
DOI: 10.1016/j.jchromb.2005.09.013
- Hesse, Christiane: Fluvoxamine affects sildenafil kinetics and dynamics / Christiane Hesse, Heike Siedler, Jürgen Burhenne, Klaus-Dieter Riedel, Walter E. Haefeli, December 2005. - 4 S.
In: Journal of clinical psychopharmacology, ISSN 1533-712X. 25(2005), 6, Seite 589-592
DOI: 10.1097/01.jcp.0000186866.82665.29
- Fröhlich, Margit: Oral contraception does not alter single dose saquinavir pharmacokinetics in women / Margit Fröhlich, Jürgen Burhenne, Meret Martin-Facklam, Johanna Weiss, Michael Von Wolff, Thomas Str… , 03 February 2004. - 9 S.
In: British journal of clinical pharmacology, ISSN 1365-2125. 57(2004), 3, Seite 244-252
DOI: 10.1111/j.1365-2125.2003.01983.x
- Ehrhardt, Manuela: Influence of lipid lowering fibrates on P-glycoprotein activity in vitro / Manuela Ehrhardt, Heike Lindenmaier, Juergen Burhenne, Walter Emil Haefeli, Johanna Weiss, 2004. - 8 S.
In: Biochemical pharmacology, ISSN 1873-2968. 67(2004), 2, Seite 285-292
DOI: 10.1016/j.bcp.2003.09.008
- Ding, Reinhard: Substantial pharmacokinetic interaction between digoxin and ritonavir in healthy volunteers / Reinhard Ding, Yorki Tayrouz, Klaus-Dieter Riedel, Jürgen Burhenne, Johanna Weiss, Gerd Mikus, and W… , 01 July 2004. - 12 S.
In: Clinical pharmacology & therapeutics, ISSN 1532-6535. 76(2004), 1, Seite 73-84
DOI: 10.1016/j.clpt.2004.02.008
- Alkan, Yoav: Voriconazole-induced QT interval prolongation and ventricular tachycardia : a non-concentration-dependent adverse effect / Y. Alkan, W.E. Haefeli, J. Burhenne, J. Stein, I. Yaniv, and I. Shalit, 15 September 2004. - 4 S.
In: Clinical infectious diseases, ISSN 1537-6591. 39(2004), 6, Seite e49-e52
DOI: 10.1086/423275
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In: British journal of clinical pharmacology, ISSN 1365-2125. 58(2004), 4, Seite 437-441
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