heiBIB: Jones, David T. W.

Jones, David T. W. Dr.Universität HeidelbergHeidelberg

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Publications in heiBIB

Jessa, Selin: FOXR2 targets LHX6+/DLX+ neural lineages to drive central nervous system neuroblastoma / Selin Jessa, Antonella De Cola, Bhavyaa Chandarana, Michael McNicholas, Steven Hébert, Adam Ptack, D… , November 4, 2024. - 20 S. : Illustrationen
In: Cancer research, ISSN 1538-7445. 85(2025), 2, Seite 231-250
DOI: 10.1158/0008-5472.CAN-24-2248
Okonechnikov, Konstantin: Oncogene aberrations drive medulloblastoma progression, not initiation / Konstantin Okonechnikov, Piyush Joshi, Verena Körber, Anne Rademacher, Michele Bortolomeazzi, Jan-Ph… , 07 May 2025. - 34 S.
In: Nature, ISSN 1476-4687. 642(2025), 8069, Seite 1062-1072
DOI: 10.1038/s41586-025-08973-5
Tauziède-Espariat, Arnault: Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype / Arnault Tauziède-Espariat, Lea L. Friker, Gunther Nussbaumer, Brigitte Bison, Volodia Dangouloff-Ros… , 18 November 2024. - 11 S. : Illustrationen
In: Acta Neuropathologica Communications, ISSN 2051-5960. 12(2024), 1, Seite 1-11
DOI: 10.1186/s40478-024-01881-1
Sievers, Philipp: Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations / Philipp Sievers, Franck Bielle, Kirsten Göbel, Daniel Schrimpf, Lucia Nichelli, Bertrand Mathon, Rom… , 18 July 2024. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 148(2024), 1, Artikel-ID 7, Seite 1-5
DOI: 10.1007/s00401-024-02766-2
Kocher, Daniela: Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines / Daniela Kocher, Lei Cao, Romain Guiho, Melanie Langhammer, Yun-Lu Lai, Pauline Becker, Hiba Hamdi, D… , 17 April 2024. - 16 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 168(2024), 2 vom: Juni, Seite 317-332
DOI: 10.1007/s11060-024-04672-9
Müller, Sabine: Consensus framework for conducting phase I/II clinical trials for children, adolescents, and young adults with pediatric low-grade glioma : guidelines established by the International Pediatric Low-Grade Glioma Coalition Clinical Trial Working Group / Sabine Mueller, Jason Fangusaro, Arzu Onar Thomas, Thomas S Jacques, Pratiti Bandopadhayay, Peter de… , 2024
In: Neuro-Oncology, ISSN 1523-5866. 26(2024), 3 vom: März, Seite 407-416
DOI: 10.1093/neuonc/noad227
Obrecht-Sturm, Denise: Pineal anlage tumor : clinical and diagnostic features, and rationales for treatment / Denise Obrecht-Sturm, Elke Pfaff, Martin Mynarek, Brigitte Bison, Martina Rodehüser, Martina Becker,… , 22 January 2024. - 10 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 166(2024), 2 vom: Jan., Seite 359-368
DOI: 10.1007/s11060-023-04547-5
Trkova, Katerina: Clinical and molecular study of radiation-induced gliomas / Katerina Trkova, David Sumerauer, Adela Bubenikova, Lenka Krskova, Ales Vicha, Miroslav Koblizek, Jo… , 2024. - 9 S. : Illustrationen
In: Scientific reports, ISSN 2045-2322. 14(2024), Artikel-ID 3118, Seite 3118-1-3118-9
DOI: 10.1038/s41598-024-53434-0
Okonechnikov, Konstantin: Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations / Konstantin Okonechnikov, Daniel Schrimpf, Jan Koster, Philipp Sievers, Till Milde, Felix Sahm, David… , 07 June 2024. - 11 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 147(2024), Artikel-ID 95, Seite 1-11
DOI: 10.1007/s00401-024-02746-6
Zuckermann, Marc: Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy / Marc Zuckermann, Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Brandon Bianski, Jia Xie,… , 07 June 2024. - 19 S. : Illustrationen
In: Molecular cancer, ISSN 1476-4598. 23(2024), Artikel-ID 123, Seite 1-19
DOI: 10.1186/s12943-024-02027-6
Tilburg, Cornelis M. van: LOGGIC/FIREFLY-2 : a phase 3, randomized trial of tovorafenib vs. chemotherapy in pediatric and young adult patients with newly diagnosed low-grade glioma harboring an activating RAF alteration / Cornelis M. van Tilburg, Lindsay B. Kilburn, Sébastien Perreault, Rene Schmidt, Amedeo A. Azizi, Ofe… , 30 January 2024. - 11 S. : Illustrationen
In: BMC cancer, ISSN 1471-2407. 24(2024), Artikel-ID 147, Seite 1-11
DOI: 10.1186/s12885-024-11820-x
Daenekas, Bjarne: Conumee 2.0 : enhanced copy-number variation analysis from DNA methylation arrays for humans and mice / Bjarne Daenekas, Eilís Pérez, Fabio Boniolo, Sabina Stefan, Salvatore Benfatto, Martin Sill, Dominik… , February 2024. - 11 S. : Illustrationen
In: Bioinformatics, ISSN 1367-4811. 40(2024), 2 vom: Feb., Artikel-ID btae029, Seite 1-11
DOI: 10.1093/bioinformatics/btae029
Ghasemi, David R.: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage / David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna S… , 08 January 2024. - 20 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 269, Seite 1-20
DOI: 10.1038/s41467-023-44117-x
Heipertz, Anna-Elisa: Outcome of children and adolescents with relapsed/refractory/progressive malignancies treated with molecularly informed targeted drugs in the pediatric precision oncology registry INFORM / Anna-Elisa Heipertz, MD, Kristian W. Pajtler, MD, Elke Pfaff, MD, Kathrin Schramm, Dr. rer. nat., Mi… , June 26, 2023. - 12 S. : Illustrationen
In: JCO precision oncology, ISSN 2473-4284. (2023), 7, Artikel-ID e2300015, Seite 1-12
DOI: 10.1200/PO.23.00015
Kolodziejczak, Anna: Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome / Anna S Kolodziejczak, Lea Guerrini-Rousseau, Julien Masliah Planchon, Jonas Ecker, Florian Selt, Mar… , December 2023. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 12 vom: Dez., Seite 2273-2286
DOI: 10.1093/neuonc/noad114
White, Christine: Implementation of DNA methylation array profiling in pediatric central nervous system tumors : the AIM BRAIN project : an Australian and New Zealand children's haematology/oncology group study / Christine L. White, Kathryn M. Kinross, Molly K. Moore, Elnaz Rasouli, Robyn Strong, Janelle M. Jone… , October 2023. - 20 S. : Illustrationen
In: The journal of molecular diagnostics, ISSN 1943-7811. 25(2023), 10 vom: Okt., Seite 709-728
DOI: 10.1016/j.jmoldx.2023.06.013
Selt, Florian: Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T : evaluation of a modeling workflow / Florian Selt, Ahmed El Damaty, Martin U. Schuhmann, Romain Sigaud, Jonas Ecker, Philipp Sievers, Dan… , 24 November 2023. - 12 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 165(2023), 3 vom: Nov., Seite 467-478
DOI: 10.1007/s11060-023-04500-6
Mynarek, Martin: Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts / Martin Mynarek, Denise Obrecht, Martin Sill, Dominik Sturm, Katja Kloth-Stachnau, Florian Selt, Jona… , 2 December 2022. - 16 S. : Illustrationen, Diagramme
In: Acta neuropathologica, ISSN 1432-0533. 145(2023), 1, Seite 97-112
DOI: 10.1007/s00401-022-02522-4
Sigaud, Romain: MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas / Romain Sigaud, Thomas K. Albert, Caroline Hess, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Ca… , 27 July 2023. - 21 S.
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 4533, Seite 1-21
DOI: 10.1038/s41467-023-40235-8
Rahmanzade, Ramin: Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics / Ramin Rahmanzade, Elke Pfaff, Rouzbeh Banan, Philipp Sievers, Abigail K. Suwala, Felix Hinz, Henri B… , 30 September 2023. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 146(2023), 6, Seite 853-856
DOI: 10.1007/s00401-023-02638-1
Okonechnikov, Konstantin: Mapping pediatric brain tumors to their origins in the developing cerebellum / Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, M… , October 2023. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 10 vom: Okt., Seite 1895-1909
DOI: 10.1093/neuonc/noad124
Nabbi, Arash: Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours / Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S.Y. … , 2023. - 24 S.
In: Genome medicine, ISSN 1756-994X. 15(2023), Artikel-ID 67, Seite 1-24
DOI: 10.1186/s13073-023-01219-x
Moreno, Lucas: Combination early-phase trials of anticancer agents in children and adolescents / Lucas Moreno, Steven G. DuBois, Julia Glade Bender, Audrey Mauguen, Nick Bird, Vickie Buenger, Miche… , June 20, 2023. - 16 S.
In: Journal of clinical oncology, ISSN 1527-7755. 41(2023), 18 vom: Juni, Seite 3408-3422
DOI: 10.1200/JCO.22.02430
Kommoss, Felix: Genomic characterization of DICER1-associated neoplasms uncovers molecular classes / Felix K.F. Kommoss, Anne-Sophie Chong, Anne-Laure Chong, Elke Pfaff, David T. W. Jones, Laura S. Hie… , 2023. - 13 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 1677, Seite 1-13
DOI: 10.1038/s41467-023-37092-w
Funke, Viktoria: Group-specific cellular metabolism in Medulloblastoma / Viktoria L.E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, … , 05 June 2023. - 16 S. : Illustrationen
In: Journal of translational medicine, ISSN 1479-5876. 21(2023), Artikel-ID 363, Seite 1-16
DOI: 10.1186/s12967-023-04211-6
Sievers, Philipp: Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature / Philipp Sievers, Martin Sill, Daniel Schrimpf, Zied Abdullaev, Andrew M. Donson, Jessica A. Lake, De… , 2023. - 8 S. : Illustrationen
In: npj precision oncology, ISSN 2397-768X. 7(2023), Artikel-ID 30, Seite 1-8
DOI: 10.1038/s41698-023-00372-1
Ecker, Jonas: Corrigendum to ‘Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry’ [Eur J Cancer 180 (2023) 71-84] / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , May 2023. - 2 S.
In: European journal of cancer, ISSN 1879-0852. 184(2023) vom: Mai, Seite 200-201
DOI: 10.1016/j.ejca.2023.02.024
Thatikonda, Venu: Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers / Venu Thatikonda, S.M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne N. Gröbner, Gregor W… , 26 January 2023. - 28 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 2 vom: Jan., Seite 276-289
DOI: 10.1038/s43018-022-00509-4
Ecker, Jonas: Molecular diagnostics enables detection of actionable targets : the Pediatric Targeted Therapy 2.0 registry / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , February 2023. - 14 S. : Illustrationen
In: European journal of cancer, ISSN 1879-0852. 180(2023) vom: Feb., Seite 71-84
DOI: 10.1016/j.ejca.2022.11.015
Sturm, Dominik: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology / Dominik Sturm, David Capper, Felipe Andreiuolo, Marco Gessi, Christian Kölsche, Annekathrin Reinhard… , 16 March 2023. - 10 S.
In: Nature medicine, ISSN 1546-170X. 29(2023), 4, Seite 917-926
DOI: 10.1038/s41591-023-02255-1
Patel, Areeba: Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study : correspondence / Areeba Patel, Helin Dogan, Alexander Payne, Elena Krause, Philipp Sievers, Natalie Schoebe, Daniel S… , 31 March 2022. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 143(2022), 5, Seite 609-612
DOI: 10.1007/s00401-022-02415-6
Kardo, Helin: Single-cell DNA sequencing reveals order of mutational acquisition in TRAF7/AKT1 and TRAF7/KLF4 mutant meningiomas : correspondence / Helin Dogan, Christina Blume, Areeba Patel, Gerhard Jungwirth, Lisa Sogerer, Miriam Ratliff, Ralf Ke… , Oktober 2022. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 144(2022), 4, Seite 799-802
DOI: 10.1007/s00401-022-02485-6
Jurmeister, Philipp: DNA methylation-based classification of sinonasal tumors / Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Liliana H. Mo… , 28 November 2022. - 14 S.
In: Nature Communications, ISSN 2041-1723. 13(2022), Artikel-ID 7148, Seite 1-14
DOI: 10.1038/s41467-022-34815-3
Langenberg, Karin: Implementation of paediatric precision oncology into clinical practice : the individualized therapies for children with cancer program ‘iTHER’ / Karin P.S. Langenberg, Michael T. Meister, Jette J. Bakhuizen, Judith M. Boer, Natasha K.A. van Eijk… , 29 September 2022. - 15 S.
In: European journal of cancer, ISSN 1879-0852. 175(2022), Seite 311-325
DOI: 10.1016/j.ejca.2022.09.001
Peterziel, Heike: Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM / Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yann… , 27 December 2022. - 17 S.
In: npj precision oncology, ISSN 2397-768X. 6(2022), Artikel-ID 94, Seite 1-17
DOI: 10.1038/s41698-022-00335-y
Blattner-Johnson, Mirjam: Precision medicine in pediatric solid cancers / Mirjam Blattner-Johnson, David T.W. Jones, Elke Pfaff, September 2022. - 14 S.
In: Seminars in cancer biology, ISSN 1096-3650. 84(2022), Seite 214-227
DOI: 10.1016/j.semcancer.2021.06.008
Tsai, Jessica W.: FOXR2 Is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits / Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin … , September 02 2022. - 22 S.
In: Cancer research, ISSN 1538-7445. 82(2022), 17, Seite 2980-3001
DOI: 10.1158/0008-5472.CAN-22-0671
Ebrahimi, Azadeh: Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival / Azadeh Ebrahimi, Andrey Korshunov, Guido Reifenberger, David Capper, Joerg Felsberg, Elena Trisolini… , Jan 10 2022. - 10 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 10(2022), Artikel-ID 5, Seite 1-10
DOI: 10.1186/s40478-021-01308-1
Catanzaro, Giuseppina: MiR-1248 : a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression / Giuseppina Catanzaro, Zein Mersini Besharat, Andrea Carai, Natalie Jäger, Elena Splendiani, Carole C… , 17 June 2022. - 17 S.
In: Biomarker Research, ISSN 2050-7771. 10(2022), Artikel-ID 44, Seite 1-17
DOI: 10.1186/s40364-022-00389-x
Beck, Pengbo: The genomic landscape of pediatric renal cell carcinomas / Pengbo Beck, Barbara Selle, Lukas Madenach, David T.W. Jones, Christian Vokuhl, Apurva Gopisetty, Ar… , April 15, 2022. - 24 S.
In: iScience, ISSN 2589-0042. 25(2022), 4 vom: 15. Apr., Artikel-ID 104167, Seite 1-24
DOI: 10.1016/j.isci.2022.104167
Gatzweiler, Charlotte: Functional therapeutic target validation using pediatric zebrafish xenograft models / Charlotte Gatzweiler, Johannes Ridinger, Sonja Herter, Xenia F. Gerloff, Dina ElHarouni, Yannick Ber… , 8 February 2022. - 24 S.
In: Cancers, ISSN 2072-6694. 14(2022), 3, Artikel-ID 849, Seite 1-24
DOI: 10.3390/cancers14030849
Sievers, Philipp: GOPC : ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types / Philipp Sievers, Damian Stichel, Martin Sill, Daniel Schrimpf, Dominik Sturm, Florian Selt, Jonas Ec… , 18 September 2021. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 6, Seite 1065-1069
DOI: 10.1007/s00401-021-02369-1
Kölsche, Christian: Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature / Christian Koelsche, Jamal K. Benhamida, Felix K. F. Kommoss, Damian Stichel, David T. W. Jones, Stef… , December 2021. - 8 S.
In: Modern pathology, ISSN 1530-0285. 34(2021), 12 vom: Dez., Seite 2122-2129
DOI: 10.1038/s41379-021-00874-y
Suwala, Abigail Kora: Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1 / Abigail K. Suwala, Damian Stichel, Daniel Schrimpf, Sybren L.N. Maas, Martin Sill, Hildegard Dohmen,… , 19 April 2021. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 1, Seite 179-189
DOI: 10.1007/s00401-021-02302-6
Kommoss, Felix: Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract : evidence for a distinct DICER1-associated subgroup / Felix K.F. Kommoss, Damian Stichel, Jaume Mora, Manel Esteller, David T.W. Jones, Stefan M. Pfister,… , 12 April 2021. - 12 S.
In: Modern pathology, ISSN 1530-0285. 34(2021), 8, Seite 1558-1569
DOI: 10.1038/s41379-021-00804-y
Deng, Maximilian: Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B / Maximilian Y. Deng, Dominik Sturm, Elke Pfaff, Martin Sill, Damian Stichel, Gnana Prakash Balasubram… , 20 September 2021. - 11 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 5530, Seite 1-11
DOI: 10.1038/s41467-021-25708-y
Barenboim, Maxim: DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma / Maxim Barenboim, Michal Kovac, Baptiste Ameline, David T. W. Jones, Olaf Witt, Stefan Bielack, Stefa… , November 11, 2021. - 24 S.
In: PLoS Computational Biology, ISSN 1553-7358. 17(2021), 11, Artikel-ID e1009562, Seite 1-24
DOI: 10.1371/journal.pcbi.1009562
Sievers, Philipp: Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors / Philipp Sievers, Sophie C. Henneken, Christina Blume, Martin Sill, Daniel Schrimpf, Damian Stichel, … , 05 August 2021. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 5, Seite 827-839
DOI: 10.1007/s00401-021-02356-6
Zheng, Tuyu: Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas / Tuyu Zheng, David R. Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K. Maas… , April 20, 2021. - 18 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 9, Seite 2230-2247
DOI: 10.1158/2159-8290.CD-20-0963
Korshunov, Andrey: Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator / Andrey Korshunov, Konstantin Okonechnikov, Damian Stichel, Marina Ryzhova, Daniel Schrimpf, Felix Sa… , 16 February 2021. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 9, Seite 1576-1585
DOI: 10.1093/neuonc/noab031
Müller, Michael: Combining APR-246 and HDAC-inhibitors : a novel targeted treatment option for neuroblastoma / Michael Müller, Lisa Rösch, Sara Najafi, Charlotte Gatzweiler, Johannes Ridinger, Xenia F. Gerloff, … , 5 September 2021. - 23 S.
In: Cancers, ISSN 2072-6694. 13(2021), 17, Artikel-ID 4476, Seite 1-23
DOI: 10.3390/cancers13174476
Maas, Sybren L. N.: Integrated molecular-morphologic meningioma classification : a multicenter retrospective analysis, retrospectively and prospectively validated / Sybren L.N. Maas, Damian Stichel, Thomas Hielscher, Philipp Sievers, Anna S. Berghoff, Daniel Schrim… , October 7, 2021. - 14 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 34, Seite 3839-3852
DOI: 10.1200/JCO.21.00784
Suwala, Abigail Kora: Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis / Abigail K. Suwala, Damian Stichel, Daniel Schrimpf, Matthias Kloor, Annika K. Wefers, Annekathrin Re… , 2021. - 16 S.
In: Acta neuropathologica, ISSN 1432-0533. 141(2021), 1, Seite 85-100
DOI: 10.1007/s00401-020-02243-6
Tilburg, Cornelis M. van: The pediatric precision oncology INFORM registry : clinical outcome and benefit for patients with very high-evidence targets / Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler, Karin P. S. Langenberg, Petra Fiesel, Barb… , August 9, 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 11, Seite 2764-2779
DOI: 10.1158/2159-8290.CD-21-0094
Sievers, Philipp: A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR / Philipp Sievers, Martin Sill, Daniel Schrimpf, Damian Stichel, David E. Reuss, Dominik Sturm, Jürgen… , 2021. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 1, Seite 34-43
DOI: 10.1093/neuonc/noaa251
Sievers, Philipp: Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1 / Philipp Sievers, Martin Sill, Christina Blume, Arnault Tauziede-Espariat, Daniel Schrimpf, Damian St… , 2021. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 141(2021), 2, Seite 281-290
DOI: 10.1007/s00401-020-02247-2
Pfaff, Elke: NTRK alterations in pediatric high-risk malignancies identified through European clinical sequencing programs constitute promising drug targets / Elke Pfaff, Tiphaine Adam de Beaumais, Antonin Marchais, Cornelis M. van Tilburg, Mirjam Blattner-Jo… , February 26, 2021. - 5 S.
In: JCO precision oncology, ISSN 2473-4284. 5(2021), Seite 450-454
DOI: 10.1200/PO.20.00417
Kumar, Rahul: Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma / Rahul Kumar, PhD; Kyle S. Smith, PhD; Maximilian Deng, MD; Colt Terhune, BA; Giles W. Robinson, MD; … , January 27, 2021. - 18 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 7, Seite 807-821
DOI: 10.1200/JCO.20.01359
Kölsche, Christian: Sarcoma classification by DNA methylation profiling / Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam… , 21 January 2021. - 10 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 498, Seite 1-10
DOI: 10.1038/s41467-020-20603-4
Korshunov, Andrey: Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation / Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian… , 03 February 2021. - 12 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 9(2021), Artikel-ID 20, Seite 1-12
DOI: 10.1186/s40478-021-01118-5
Stainczyk, Sabine: Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome / Sabine A. Hartlieb, Lina Sieverling, Michal Nadler-Holly, Matthias Ziehm, Umut H. Toprak, Carl Herrm… , 24 February 2021. - 18 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 1269, Seite 1-18
DOI: 10.1038/s41467-021-21247-8
Haag, Daniel: H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model / Daniel Haag, Norman Mack, Patricia Benites Goncalves da Silva, Britta Statz, Jessica Clark, Koji Tan… , 4 February 2021. - 29 S.
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Hovestadt, Volker: Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays / Volker Hovestadt, Marc Remke, Marcel Kool, Torsten Pietsch, Paul A. Northcott, Roger Fischer, Floren… , 14 May 2013. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 6, Seite 913-916
DOI: 10.1007/s00401-013-1126-5
Lambert, Sally R.: Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma / Sally R. Lambert, Hendrik Witt, Volker Hovestadt, Manuela Zucknick, Marcel Kool, Danita M. Pearson, … , 10 May 2013. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 2 vom: Aug., Seite 291-301
DOI: 10.1007/s00401-013-1124-7
Jones, David T. W.: The role of chromatin remodeling in medulloblastoma / David T.W. Jones; Paul A. Northcott; Marcel Kool; Stefan M. Pfister, 25 February 2013. - 7 S.
In: Brain pathology, ISSN 1750-3639. 23(2013), 2 vom: März, Seite 193-199
DOI: 10.1111/bpa.12019
Dubuc, Adrian M.: Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma / Adrian M. Dubuc, Marc Remke, Andrey Korshunov, Paul A. Northcott, Shing H. Zhan, Maria Mendez-Lago, … , 2013. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 373-384
DOI: 10.1007/s00401-012-1070-9
Bender, Sebastian: Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas / Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, David T.W. Jones, Marcel Kool, M… , October 31, 2013. - 13 S.
In: Cancer cell, ISSN 1878-3686. 24(2013), 5, Seite 660-672
DOI: 10.1016/j.ccr.2013.10.006
Schweizer, Leonille: Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein / Leonille Schweizer · Christian Koelsche · Felix Sahm · Rosario M. Piro · David Capper · David E. Reu… , 2013. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 5, Seite 651-658
DOI: 10.1007/s00401-013-1117-6
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 2012. - 6 S.
In: Nature, ISSN 0028-0836. 488(2012), 7409 vom: 20. Juni, Seite 100-105
Pugh, Trevor: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations / Trevor J. Pugh, Shyamal Dilhan Weeraratne, Tenley C. Archer, Daniel A. Pomeranz Krummel, Daniel Aucl… , 22 July 2012. - 5 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 106-110
DOI: 10.1038/nature11329
Korshunov, Andrey: LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) / Andrey Korshunov, Marina Ryzhova, David T. W. Jones, Paul A. Northcott, Peter van Sluis, Richard Vol… , 16 November 2012. - 7 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 6, Seite 875-881
DOI: 10.1007/s00401-012-1068-3
Korshunov, Andrey: Biological and clinical heterogeneity of MYCN-amplified medulloblastoma / Andrey Korshunov, Marc Remke, Marcel Kool, Thomas Hielscher, Paul A. Northcott, Dan Williamson, Elke… , 2012. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 515-527
DOI: 10.1007/s00401-011-0918-8
Kool, Marcel: Molecular subgroups of medulloblastoma : an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas / Marcel Kool, Andrey Korshunov, Marc Remke, David T.W. Jones, Maria Schlanstein, Paul A. Northcott, Y… , 23 February 2012. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 473-484
DOI: 10.1007/s00401-012-0958-8
Liu, Xiao-Yang: Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations / Xiao-Yang Liu, Noha Gerges, Andrey Korshunov, Nesrin Sabha, Dong-Anh Khuong-Quang, Adam M. Fontebass… , 12 August 2012. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 5, Seite 615-625
DOI: 10.1007/s00401-012-1031-3
Northcott, Paul A.: Medulloblastomics : the end of the beginning / Paul A. Northcott, David T.W. Jones, Marcel Kool, Giles W. Robinson, Richard J. Gilbertson, Yoon-Jae… , 23 November 2012. - 17 S.
In: Nature reviews, ISSN 1474-1768. 12(2012), 12, Seite 818-834
DOI: 10.1038/nrc3410
Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 25 July 2012. - 6 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 100-105
DOI: 10.1038/nature11284
Khuong-Quang, Dong-Anh: K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas / Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M. Fontebasso, Eri… , 3 June 2012. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 3, Seite 439-447
DOI: 10.1007/s00401-012-0998-0
Schwartzentruber, Jeremy: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma / Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T.W. Jones, Elke Pfaff, Karine Jacob… , 29 January 2012. - 6 S.
In: Nature, ISSN 1476-4687. 482(2012), 7384, Seite 226-231
DOI: 10.1038/nature10833
Sturm, Dominik: Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma / Dominik Sturm; Hendrik Witt ... David T. W. Jones; Carolin Konermann; Elke Pfaff ... Sebastian Bende… , October 15, 2012. - 13 S.
In: Cancer cell, ISSN 1878-3686. 22(2012), 4, Seite 425-437
DOI: 10.1016/j.ccr.2012.08.024
Witt, Hendrik: Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma / Hendrik Witt, Stephen C. Mack, Marina Ryzhova, Sebastian Bender, Martin Sill, Ruth Isserlin, Axel Be… , August 15, 2011. - 15 S.
In: Cancer cell, ISSN 1878-3686. 20(2011), 2, Seite 143-157
DOI: 10.1016/j.ccr.2011.07.007
Gronych, Jan: An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice / Jan Gronych, Andrey Korshunov, Josephine Bageritz, Till Milde, Manfred Jugold, Dolores Hambardzumyan… , April 2011. - 5 S.
In: The journal of clinical investigation, ISSN 1558-8238. 121(2011), 4, Seite 1344-1348
DOI: 10.1172/JCI44656
Jacob, Karine: Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas / Karine Jacob, Dongh-Anh Quang-Khuong, David T.W. Jones, Hendrik Witt, Sally Lambert, Steffen Albrech… , July 17 2011. - 11 S.
In: Clinical cancer research, ISSN 1557-3265. 17(2011), 14, Seite 4650-4660
DOI: 10.1158/1078-0432.CCR-11-0127
Jones, David T. W.: MAPK pathway activation in pilocytic astrocytoma / David T.W. Jones, Jan Gronych, Peter Lichter, Olaf Witt, Stefan M. Pfister, 2012. - 13 S.
In: Cellular and molecular life sciences, ISSN 1420-9071. 69(2012), 11, Seite 1799-1811
DOI: 10.1007/s00018-011-0898-9

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