heiBIB: Fleming, Thomas

Fleming, Thomas Dr. sc. hum.Universität HeidelbergHeidelberg

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Publikationen in heiBIB

Chen, Ying: Sex differences in the development of experimental diabetic retinopathy / Ying Chen, Andrea Schlotterer, Jihong Lin, Nadine Dietrich, Thomas Fleming, Stefanie Lanzinger, Rein… , 01 October 2024. - 11 S. : Illustrationen
In: Scientific reports, ISSN 2045-2322. 14(2024), Artikel-ID 22812, Seite 1-11
DOI: 10.1038/s41598-024-73279-x
Rauchhaupt, Ekaterina von: Glucose load following prolonged fasting increases oxidative stress-linked response in individuals with diabetic complications / Ekaterina von Rauchhaupt, Claus Rodemer, Elisabeth Kliemank, Ruben Bulkescher, Marta Campos, Stefan … , [June 21 2024]. - 9 S.
In: Diabetes care, ISSN 1935-5548. 47(2024), 9, Seite 1584-1592
DOI: 10.2337/dc24-0209
Rhein, Sina: The reactive pyruvate metabolite dimethylglyoxal mediates neurological consequences of diabetes / Sina Rhein, Riccardo Costalunga, Julica Inderhees, Tammo Gürtzgen, Teresa Christina Faupel, Zaib Sha… , 10 July 2024. - 20 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 5745, Seite 1-20
DOI: 10.1038/s41467-024-50089-3
Peter, Andreas: Accumulation of non-pathological liver fat is associated with the loss of glyoxalase I activity in humans / Andreas Peter, Erwin Schleicher, Elisabeth Kliemank, Julia Szendroedi, Alfred Königsrainer, Hans-Ulr… , 7 April 2024. - 13 S.
In: Metabolites, ISSN 2218-1989. 14(2024), 4, Artikel-ID 209, Seite 209-1-209-13
DOI: 10.3390/metabo14040209
Harrer, Philip: Phenotypic and genome-wide studies on dicarbonyls : major associations to glomerular filtration rate and gamma-glutamyltransferase activity / Philip Harrer, Julica Inderhees, Chen Zhao, Barbara Schormair, Erik Tilch, Christian Gieger, Annette… , March 2024. - 11 S. : Illustrationen
In: EBioMedicine, ISSN 2352-3964. 101(2024) vom: März, Artikel-ID 105007, Seite 1-11
DOI: 10.1016/j.ebiom.2024.105007
Brings, Sebastian: Non-cross-linking advanced glycation end products affect prohormone processing / Sebastian Brings, Walter Mier, Barbro Beijer, Elisabeth Kliemank, Stephan Herzig, Julia Szendroedi, … , January 2024. - 12 S. : Illustrationen
In: The biochemical journal, ISSN 0006-2936. 481(2024), 1 vom: Jan., Seite 33-44
DOI: 10.1042/BCJ20230321
Marty-Lombardi, Sebastián: Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain / Sebastián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Anna … , 05 March 2024. - 20 S.
In: Nature metabolism, ISSN 2522-5812. (2024), Seite 1-20
DOI: 10.1038/s42255-024-01001-2
Qian, Xin: Impaired Detoxification of Trans, Trans-2,4-Decadienal, an Oxidation Product from Omega-6 Fatty Acids, Alters Insulin Signaling, Gluconeogenesis and Promotes Microvascular Disease / Xin Qian, Stephan Klatt, Katrin Bennewitz, David Philipp Wohlfart, Bowen Lou, Ye Meng, Michael Buett… , January 26, 2024. - 17 S. : Illustrationen
In: Advanced science, ISSN 2198-3844. 11(2024), 4, Artikel-ID 2302325, Seite 1-17
DOI: 10.1002/advs.202302325
Marty-Lombardi, Sebastián: Neuron-astrocyte metabolic coupling facilitates spinal plasticity and maintenance of inflammatory pain [data] / Sebstián Marty-Lombardi, Shiying Lu, Wojciech Ambroziak, Katrin Schrenk-Siemens, Jialin Wang, Anna A… . -
Heidelberg: Universität, 2024-01-26. - 1 Online-Ressource (2 Files)
DOI: 10.11588/data/AMDH7G
Özer, Kübra: The effect of GLP-1 receptor agonist lixisenatide on experimental diabetic retinopathy / Kuebra Oezer, Matthias Kolibabka, Johann Gassenhuber, Nadine Dietrich, Thomas Fleming, Andrea Schlot… , November 2023. - 15 S. : Illustrationen
In: Acta diabetologica, ISSN 1432-5233. 60(2023), 11 vom: Nov., Seite 1551-1565
DOI: 10.1007/s00592-023-02135-7
Taylor, Jacqueline: Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia / Jacqueline Taylor, Leonie Uhl, Iris Moll, Sana Safatul Hasan, Lena Wiedmann, Jakob Morgenstern, Bene… , 25 September 2023. - 38 S. : Illustrationen
In: Nature cancer, ISSN 2662-1347. 4(2023), 11, Seite 1544-1560
DOI: 10.1038/s43018-023-00622-y
Rhein, Sina: Glyoxal in hyperglycaemic ischemic stroke - a cohort study / Sina Rhein, Julica Inderhees, Oliver Herrmann, Alaa Othman, Kimberly Begemann, Thomas Fleming, Peter… , 2023. - 9 S. : Illustrationen
In: Cardiovascular diabetology, ISSN 1475-2840. 22(2023), Artikel-ID 173, Seite 1-9
DOI: 10.1186/s12933-023-01892-7
Tabler, Christoph Tobias: Loss of glyoxalase 2 alters the glucose metabolism in zebrafish / Christoph Tobias Tabler, Elisabeth Lodd, Katrin Bennewitz, Chiara Simone Middel, Vanessa Erben, Hann… , 2023. - 15 S.
In: Redox Biology, ISSN 2213-2317. 59(2023) vom: Feb., Artikel-ID 102576, Seite 1-15
DOI: 10.1016/j.redox.2022.102576
Weis, Eva-Maria: Ketone body oxidation increases cardiac endothelial cell proliferation / Eva‐Maria Weis, Patrycja Puchalska, Alisa B Nelson, Jacqueline Taylor, Iris Moll, Sana S Hasan, Matt… , Apr 2022. - 18 S.
In: EMBO molecular medicine, ISSN 1757-4684. 14(2022), 4 vom: Apr., Artikel-ID e14753, Seite 1-18
DOI: 10.15252/emmm.202114753
Hemmersbach, Lars: Synthesis and biological evaluation of water-soluble esterase-activated CO-releasing molecules targeting mitochondria / Lars Hemmersbach, Yannick Schreiner, Xinmiao Zhang, Finn Dicke, Leon Hünemeyer, Jörg-Martin Neudörfl… , September 6, 2022. - 9 S.
In: Chemistry - a European journal, ISSN 1521-3765. 28(2022), 50 vom: Sept., Artikel-ID 202201670, Seite 1-9
DOI: 10.1002/chem.202201670
Kender, Zoltán: Diabetic neuropathy is a generalized phenomenon with impact on hand functional performance and quality of life / Zoltan Kender, Jan B. Groener, Johann M.E. Jende, Felix T. Kurz, Thomas Fleming, Alba Sulaj, Sigrid … , October 2022. - 11 S.
In: European journal of neurology, ISSN 1468-1331. 29(2022), 10 vom: Okt., Seite 3081-3091
DOI: 10.1111/ene.15446
Al-Saoudi, Elaf: Advanced glycation end-products are associated with diabetic neuropathy in young adults with type 1 diabetes / Elaf Al-Saoudi, Marie M. B. Christensen, Peter Nawroth, Thomas Fleming, Eva E. Hommel, Marit E. Jørg… , 11 October 2022. - 13 S.
In: Frontiers in endocrinology, ISSN 1664-2392. 13(2022), Artikel-ID 891442, Seite 1-13
DOI: 10.3389/fendo.2022.891442
Gegner, Hagen M.: Deep metabolic profiling assessment of tissue extraction protocols for three model organisms / Hagen M. Gegner, Nils Mechtel, Elena Heidenreich, Angela Wirth, Fabiola Garcia Cortizo, Katrin Benne… , 25 April 2022. - 11 S.
In: Frontiers in Chemistry, ISSN 2296-2646. 10(2022) vom: Apr., Artikel-ID 869732, Seite 1-11
DOI: 10.3389/fchem.2022.869732
Gancheva, Sofiya: Impaired hepatic mitochondrial capacity in nonalcoholic steatohepatitis associated with Type 2 diabetes / Sofiya Gancheva, Sabine Kahl, Dominik Pesta, Lucia Mastrototaro, Bedair Dewidar, Klaus Strassburger,… , February 03 2022. - 10 S.
In: Diabetes care, ISSN 1935-5548. 45(2022), 4, Seite 928-937
DOI: 10.2337/dc21-1758
Garcia Cortizo, Fabiola: The activity of glyoxylase 1 is regulated by glucose-responsive phosphorylation on Tyr136 / Fabiola Garcia Cortizo, Daniel Pfaff, Angela Wirth, Andrea Schlotterer, Rebekka Medert, Jakob Morgen… , 2022. - 11 S.
In: Molecular metabolism, ISSN 2212-8778. 55(2022) vom: Jan., Artikel-ID 101406, Seite 1-11
DOI: 10.1016/j.molmet.2021.101406
Murillo, Katharina: Protective effects of transient glucose exposure in adult C. elegans / Katharina Murillo, Azat Samigullin, Per M. Humpert, Thomas Fleming, Kübra Özer, Andrea Schlotterer, … , 14 January 2022. - 8 S.
In: Antioxidants, ISSN 2076-3921. 11(2022), 1, Artikel-ID 160, Seite 1-8
DOI: 10.3390/antiox11010160
Wohlfart, David Philipp: Accumulation of acetaldehyde in aldh2.1-/- zebrafish causes increased retinal angiogenesis and impaired glucose metabolism / David Philipp Wohlfart, Bowen Lou, Chiara Simone Middel, Jakob Morgenstern, Thomas Fleming, Carsten … , 26 January 2022. - 15 S.
In: Redox Biology, ISSN 2213-2317. 50(2022) vom: Apr., Artikel-ID 102249, Seite 1-15
DOI: 10.1016/j.redox.2022.102249
Buckert, Magdalena: Pronounced cortisol response to acute psychosocial stress in type 2 diabetes patients with and without complications / M. Buckert, M. Hartmann, N. Monzer, K. Wolff, P. Nawroth, T. Fleming, C. Streibel, N. Henningsen, B.… , 24 February 2022. - 8 S.
In: Hormones and behavior, ISSN 1095-6867. 141(2022), Artikel-ID 105120, Seite 1-8
DOI: 10.1016/j.yhbeh.2022.105120
Morgenstern, Jakob: Neuron-specific biomarkers predict hypo- and hyperalgesia in individuals with diabetic peripheral neuropathy / Jakob Morgenstern, Jan B. Groener, Johann M. E. Jende, Felix T. Kurz, Alexander Strom, Jens Göpfert,… , 03 September 2021. - 13 S.
In: Diabetologia, ISSN 1432-0428. 64(2021), 12, Seite 2843-2855
DOI: 10.1007/s00125-021-05557-6
Qi, Haozhe: Reduced acrolein detoxification in akr1a1a zebrafish mutants causes impaired insulin receptor signaling and microvascular alterations / Haozhe Qi, Felix Schmöhl, Xiaogang Li, Xin Qian, Christoph T. Tabler, Katrin Bennewitz, Carsten Stic… , July 18, 2021. - 15 S.
In: Advanced science, ISSN 2198-3844. 8(2021), 18, Artikel-ID 2101281, Seite 1-15
DOI: 10.1002/advs.202101281
Altamura, Sandro: Iron aggravates hepatic insulin resistance in the absence of inflammation in a novel db/db mouse model with iron overload / Sandro Altamura, Katja Müdder, Andrea Schlotterer, Thomas Fleming, Elena Heidenreich, Ruiyue Qiu, Ha… , September 2021. - 13 S.
In: Molecular metabolism, ISSN 2212-8778. 51(2021) vom: Sept., Artikel-ID 101235, Seite 1-13
DOI: 10.1016/j.molmet.2021.101235
Kopf, Stefan: Diabetic pneumopathy : a new diabetes-associated complication: mechanisms, consequences and treatment considerations / Stefan Kopf, Varun Kumar, Zoltan Kender, Zhe Han, Thomas Fleming, Stephan Herzig and Peter P. Nawrot… , 25 November 2021. - 11 S.
In: Frontiers in endocrinology, ISSN 1664-2392. 12(2021), Artikel-ID 765201, Seite 1-11
DOI: 10.3389/fendo.2021.765201
Strom, Alexander: Interaction between magnesium and methylglyoxal in diabetic polyneuropathy and neuronal models / Alexander Strom, Klaus Strassburger, Martin Schmuck, Hanna Shevalye, Eric Davidson, Fariba Zivehe, G… , January 2021. - 10 S.
In: Molecular metabolism, ISSN 2212-8778. 43(2021) vom: Jan., Artikel-ID 101114, Seite 1-10
DOI: 10.1016/j.molmet.2020.101114
Deshpande, Divija: Loss of POMC-mediated antinociception contributes to painful diabetic neuropathy / Divija Deshpande, Nitin Agarwal, Thomas Fleming, Claire Gaveriaux-Ruff, Christoph S.N. Klose, Anke T… , 18 January 2021. - 18 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 426, Seite 1-18
DOI: 10.1038/s41467-020-20677-0
Morgenstern, Jakob: Quantification of all-trans retinoic acid by liquid chromatography-tandem mass spectrometry and association with lipid profile in patients with Type 2 diabetes / Jakob Morgenstern, Thomas Fleming, Elisabeth Kliemank, Maik Brune, Peter Nawroth and Andreas Fischer, 19 January 2021. - 10 S.
In: Metabolites, ISSN 2218-1989. 11(2021), 1, Artikel-ID 60, Seite 1-10
DOI: 10.3390/metabo11010060
Becker, Anna K.: Reactive dicarbonyl compounds cause Calcitonin Gene-Related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum / Anna K. Becker, Andrea Auditore, Monika Pischetsrieder, Karl Messlinger, Thomas Fleming, Peter W. Re… , March 20, 2020. - 14 S.
In: The journal of biological chemistry, ISSN 1083-351X. 295(2020), 19 vom: Mai, Seite 6330-6343
DOI: 10.1074/jbc.RA120.012890
Chen, Jessy: CaM kinase II-δ is required for diabetic hyperglycemia and retinopathy but not nephropathy / Jessy Chen, Thomas Fleming, Sylvia Katz, Matthias Dewenter, Kai Hofmann, Alireza Saadatmand, Mariya … , 2021. - 11 S.
In: Diabetes, ISSN 1939-327X. 70(2021), 2, Seite 616-626
DOI: 10.2337/db19-0659
Li, Xiaogang: Regulation of gluconeogenesis by Aldo-keto-reductase 1a1b in zebrafish / Xiaogang Li, Felix Schmöhl, Haozhe Qi, Katrin Bennewitz, Christoph T. Tabler, Gernot Poschet, Rüdige… , December 18, 2020. - 29 S.
In: iScience, ISSN 2589-0042. 23(2020,12) Artikel-Nummer 101763, 29 Seiten
DOI: 10.1016/j.isci.2020.101763
Lou, Bowen: Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans / Bowen Lou, Mike Boger, Katrin Bennewitz, Carsten Sticht, Stefan Kopf, Jakob Morgenstern, Thomas Flem… , 16 September 2020. - 16 S.
In: Redox Biology, ISSN 2213-2317. 37(2020) Artikel-Nummer 101723, 16 Seiten
DOI: 10.1016/j.redox.2020.101723
Morgenstern, Jakob: The glyoxalase system : new insights into an ancient metabolism / Jakob Morgenstern, Marta Campos Campos, Peter Nawroth and Thomas Fleming, 1 October 2020. - 15 S.
In: Antioxidants, ISSN 2076-3921. 9(2020,10) Artikel-Nummer 939, 15 Seiten
DOI: 10.3390/antiox9100939
Morgenstern, Jakob: Phosphorylation of T107 by CamKII[delta] regulates the detoxification efficiency and proteomic integrity of glyoxalase 1 / Jakob Morgenstern, Sylvia Katz, Jutta Krebs-Haupenthal, Jessy Chen, Alireza Saadatmand, Fabiola Garc… , September 22, 2020. - 14 S.
In: Cell reports, ISSN 2211-1247. 32(2020,12) Artikel-Nummer 108160, 14 Seiten
DOI: 10.1016/j.celrep.2020.108160
Weigand, Tim: A global Cndp1-knock-out selectively increases renal carnosine and anserine concentrations in an age- and gender-specific manner in mice / Tim Weigand, Florian Colbatzky, Tilman Pfeffer, Sven F. Garbade, Kristina Klingbeil, Florian Colbatz… , 10 July 2020. - 20 S.
In: International journal of molecular sciences, ISSN 1422-0067. 21(2020), 14, Artikel-ID 4887, Seite 1-20
DOI: 10.3390/ijms21144887
Brings, Sebastian: Urinary cathepsin L is predictive of changes in albuminuria and correlates with glucosepane in patients with type 2 diabetes in a closed-cohort study / Sebastian Brings, Thomas Fleming, Stephan Herzig, Peter P. Nawroth, Stefan Kopf, 2 June 2020. - 7 S.
In: Journal of diabetes and its complications, ISSN 1873-460X. 34(2020,9) Artikel-Nummer 107648, 7 Seiten
DOI: 10.1016/j.jdiacomp.2020.107648
Agarwal, Nitin: SUMOylation of enzymes and ion channels in sensory neurons protects against metabolic dysfunction, neuropathy, and sensory loss in diabetes / Nitin Agarwal, Francisco J. Taberner, Daniel Rangel Rojas, Mirko Moroni, Damir Omberbasic, Christian… , July 30, 2020. - 19 S.
In: Neuron, ISSN 1097-4199. 107(2020), 6, Seite 1141-1159.e7
DOI: 10.1016/j.neuron.2020.06.037
Schwarz, Daniel: Characterization of experimental diabetic neuropathy using multicontrast magnetic resonance neurography at ultra high field strength / Daniel Schwarz, Asa S. Hidmark, Volker Sturm, Manuel Fischer, David Milford, Ingrid Hausser, Felix S… , 5 May 2020. - 12 S.
In: Scientific reports, ISSN 2045-2322. 10(2020) Artikel-Nummer 7593, 12 Seiten
DOI: 10.1038/s41598-020-64585-1
Safatul Hasan, Sana: Endothelial Notch signaling controls insulin transport in muscle / Sana S Hasan, Markus Jabs, Jacqueline Taylor, Lena Wiedmann, Thomas Leibing, Viola Nordström, Giusep… , 18 March 2020
In: EMBO molecular medicine, ISSN 1757-4684. 12(2020,4) Artikel-Nummer e09271, 17 Seiten
DOI: 10.15252/emmm.201809271
Gröner, Jan: Asprosin response in hypoglycemia is not related to hypoglycemia unawareness but rather to insulin resistance in type 1 diabetes / Jan Benedikt Groener, Aikaterini Valkanou, Zoltan Kender, Jan Pfeiffenberger, Lars Kihm, Thomas Flem… , September 19, 2019. - 11 S.
In: PLOS ONE, ISSN 1932-6203. 14(2019,9) Artikel-Nummer e0222771, 11 Seiten
DOI: 10.1371/journal.pone.0222771
Urban, Ivelina: 15-deoxy-[delta]12,14-prostaglandin J2 reinforces the anti-inflammatory capacity of endothelial cells with a genetically determined NO deficit / Urban Ivelina, Turinsky Martin, Gehrmann Sviatlana, Morgenstern Jakob, Brune Maik, Milewski Moritz R… , 19 Jun 2019. - 13 S.
In: Circulation research, ISSN 1524-4571. 125(2019), 3, Seite 282-294
DOI: 10.1161/CIRCRESAHA.118.313820
Schmöhl, Felix: CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications / Felix Schmöhl, Verena Peters, Claus Peter Schmitt, Gernot Poschet, Michael Büttner, Xiaogang Li, Tim… , 9 May 2019. - 18 S.
In: Cellular and molecular life sciences, ISSN 1420-9071. 76(2019), 22, Seite 4551-4568
DOI: 10.1007/s00018-019-03127-z
Düll, Miriam: Methylglyoxal causes pain and hyperalgesia in human through C-fiber activation / Miriam M. Düll, Kathrin Riegel, Julia Tappenbeck, Vivien Ries, Marion Strupf, Thomas Fleming, Susann… , 18 June 2019
In: Pain, ISSN 1872-6623. 160(2019), 11, Seite 2497-2507
DOI: 10.1097/j.pain.0000000000001644
Lodd, Elisabeth: The combination of loss of glyoxalase1 and obesity results in hyperglycemia / Elisabeth Lodd, Lucas M. Wiggenhauser, Jakob Morgenstern, Thomas H. Fleming, Gernot Poschet, Michael… , June 20, 2019
In: JCI insight, ISSN 2379-3708. 4(2019,12) Artikel-Nummer e126154, 17 Seiten
DOI: 10.1172/jci.insight.126154
Kronlage, Mariya: O-GlcNAcylation of histone deacetylase 4 protects the diabetic heart from failure / Mariya Kronlage, Matthias Dewenter, Johannes Grosso, Thomas Fleming, Ulrike Oehl, Lorenz H. Lehmann,… , 14 Jun 2019. - 15 S.
In: Circulation, ISSN 1524-4539. 140(2019), 7, Seite 580-594
DOI: 10.1161/CIRCULATIONAHA.117.031942
Sachdeva, Robin: Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels / Robin Sachdeva, Thomas Fleming, Dagmar Schumacher, Sarah Homberg, Kathrin Stilz, Franziska Mohr, And… , 09 January 2019. - 10 S.
In: Cell calcium, ISSN 1532-1991. 78(2019), Seite 66-75
DOI: 10.1016/j.ceca.2019.01.002
Griggs, Ryan: Methylglyoxal and a spinal TRPA1-AC1-Epac cascade facilitate pain in the db/db mouse model of type 2 diabetes / Ryan B. Griggs, Diogo F. Santos, Don E. Laird, Suzanne Doolen, Renee R. Donahue, Caitlin R. Wessel, … , 23 February 2019. - 11 S.
In: Neurobiology of disease, ISSN 1095-953X. 127(2019), Seite 76-86
DOI: 10.1016/j.nbd.2019.02.019
Peters, Andreas: Effect of metformin treatment in patients with type 2 diabetes with respect to glyoxalase 1 activity in atherosclerotic lesions / Andreas S. Peters, Markus Wortmann, Thomas H. Fleming, Peter P. Nawroth, Thomas Bruckner, Dittmar Bö… , [2019]. - 7 S. : Illustrationen
In: Vasa, ISSN 1664-2872. 48(2019), 2, Seite 186-192
DOI: 10.1024/0301-1526/a000762
Schmitt, Felix: Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality: results of an observational pilot study / Felix Carl Fabian Schmitt, Vasil Manolov, Jakob Morgenstern, Thomas Fleming, Stefan Heitmeier, Flori… . -
Heidelberg: Springer, 20 Mrz 2019. - 1 Online-Ressource (15 Seiten)
DOI: 10.1186/s13613-019-0499-6
Schlotterer, Andrea: Methylglyoxal induces retinopathy-type lesions in the absence of hyperglycemia : studies in a rat model / Andrea Schlotterer, Matthias Kolibabka, Jihong Lin, Kübra Acunman, Nadine Dietrich, Carsten Sticht, … , 27 Feb 2019. - 13 S.
In: The FASEB journal, ISSN 1530-6860. 33(2019), 3, Seite 4141-4153
DOI: 10.1096/fj.201801146RR
Schmitt, Felix: Acute fibrinolysis shutdown occurs early in septic shock and is associated with increased morbidity and mortality : results of an observational pilot study / Felix Carl Fabian Schmitt, Vasil Manolov, Jakob Morgenstern, Thomas Fleming, Stefan Heitmeier, Flori… , 30 January 2019. - 15 S.
In: Annals of intensive care, ISSN 2110-5820. 9(2019) Artikel-Nummer 19, 15 Seiten
DOI: 10.1186/s13613-019-0499-6
Gröner, Jan: Methylglyoxal and advanced glycation end products in patients with diabetes : what we know so far and the missing links / Jan Benedikt Groener, Dimitrios Oikonomou, Ruan Cheko, Zoltan Kender, Johanna Zemva, Lars Kihm, Mart… , 2019. - 8 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 127(2019), 8, Seite 497-504
DOI: 10.1055/s-0043-106443
Andersen, Signe Toft: Risk factors for incident diabetic polyneuropathy in a cohort with screen-detected type 2 diabetes followed for 13 years : ADDITION-Denmark / Signe T. Andersen, Daniel R. Witte, Else-Marie Dalsgaard, Henning Andersen, Peter Nawroth, Thomas Fl… , 6 February 2018. - 8 S.
In: Diabetes care, ISSN 1935-5548. 41(2018), 5, Seite 1068-1075
DOI: 10.2337/dc17-2062
Peters, Verena: Protective actions of anserine under diabetic conditions / Verena Peters, Vittorio Calabrese, Elisabete Forsberg, Nadine Volk, Thomas Fleming, Hans Baelde, Tim… , 13 September 2018. - 12 S.
In: International journal of molecular sciences, ISSN 1422-0067. 19(2018,9) Artikel-Nummer 2751, 12 Seiten
DOI: 10.3390/ijms19092751
Micakovic, Tamara: The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus / Tamara Micakovic, Stamatia Papagiannarou, Euan Clark, Yalcin Kuzay, Katarina Abramovic, Jörg Peters,… , 4 September 2018. - 14 S.
In: Kidney international, ISSN 1523-1755. 94(2018), 5, Seite 937-950
DOI: 10.1016/j.kint.2018.06.006
Schmitt, Felix: Cell cycle arrest and cell death correlate with the extent of ischaemia and reperfusion injury inpatients following kidney transplantation : results of an observational pilot study / Felix C.F. Schmitt, Eduardo Salgado, Janina Friebe, Thomas Schmoch, Florian Uhle, Thomas Fleming, Jo… , 30 March 2018. - 10 S.
In: Transplant international, ISSN 1432-2277. 31(2018), 7, Seite 751-760
DOI: 10.1111/tri.13148
Mendler, Michael: Urine levels of 5-aminoimidazole-4-carboxamide riboside (AICAR) in patients with type 2 diabetes / Michael Mendler, Stefan Kopf, Jan B. Groener, Christin Riedinger, Thomas H. Fleming, Peter P. Nawrot… , 2018. - 8 S.
In: Acta diabetologica, ISSN 1432-5233. 55(2018), 6, Seite 585-592
DOI: 10.1007/s00592-018-1130-2
Bauer, Rüdiger von: Pleiotropic effect of lipoprotein-apheresis on the soluble form of activated leukocyte Cell adhesion molecule (sALCAM) in familial hypercholesterolaemia / Rüdiger von Bauer, Dimitrios Oikonomou, Alba Sulaj, Stefan Kopf, Thomas Fleming, Gottfried Rudofsky,… , 2019. - 5 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 127(2019), 5, Seite 276-280
DOI: 10.1055/a-0630-0232
Patry, Christian: Endothelial progenitor cells accelerate endothelial regeneration in an in vitro model of Shigatoxin-2a-induced injury via soluble growth factors / Christian Patry, Christian Betzen, Farnoosh Fathalizadeh, Alexander Fichtner, Jens H. Westhoff, Thom… , [2018]. - 9 S. : Illustrationen
In: American journal of physiology, ISSN 1522-1466. 315(2018), 4, Seite F861-F869
DOI: 10.1152/ajprenal.00633.2017
Riedinger, Christin: High-glucose toxicity is mediated by AICAR-transformylase/IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans / Christin Riedinger, Michael Mendler, Andrea Schlotterer, Thomas Fleming, Jürgen Okun, Hans-Peter Ham… , February 2, 2018. - 16 S.
In: The journal of biological chemistry, ISSN 1083-351X. 293(2018), 13, Seite 4845-4859
Zemva, Johanna: Effects of the reactive metabolite methylglyoxal on cellular signalling, insulin action and metabolism - What we know in mammals and what we can learn from yeast / Johanna Zemva, Daniel Pfaff, Jan B. Groener, Thomas Fleming, Stephan Herzig, Aurelio Teleman, Peter … , 2019. - 12 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 127(2019), 4, Seite 203-214
DOI: 10.1055/s-0043-122382
Korkmaz-İçöz, Sevil: Impairment of the Akt pathway in transplanted Type 1 diabetic hearts is associated with post-transplant graft injury / Sevil Korkmaz-Icöz, Shiliang Li, Sivakkanan Loganathan, Tamás Radovits, Mihály Ruppert, Paige Brleci… , 14 June 2018. - 11 S.
In: Interactive cardiovascular and thoracic surgery, ISSN 1569-9285. 27(2018), 6, Seite 884-894
DOI: 10.1093/icvts/ivy188
Kopf, Stefan: Deep phenotyping neuropathy : an underestimated complication in patients with pre-diabetes and type 2 diabetes associated with albuminuria / Stefan Kopf, Jan B. Groener, Zoltan Kender, Thomas Fleming, Sandra Bischoff, Johann Jende, Carsten S… , 31 October 2018. - 11 S.
In: Diabetes research and clinical practice, ISSN 1872-8227. 146(2018), Seite 191-201
DOI: 10.1016/j.diabres.2018.10.020
Murillo, Katharina: Plate-based large-scale cultivation of Caenorhabditis elegans : sample preparation for the study of metabolic alterations in diabetes / Katharina Kohl, Thomas Fleming, Kübra Acunman, Hans-Peter Hammes, Michael Morcos, Andrea Schlotterer, 8/24/2018. - 1 Online-Ressource (1 Videodatei, 2:00 min) : farbig
In: JoVE, ISSN 1940-087X. (2018), 138, Artikel-ID e58117, Seite 1-8
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Senyilmaz-Tiebe, Deniz: Dietary stearic acid regulates mitochondria in vivo in humans / Deniz Senyilmaz-Tiebe, Daniel H. Pfaff, Sam Virtue, Kathrin V. Schwarz, Thomas Fleming, Sandro Altam… , 07 August 2018. - 10 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 3129, 10 Seiten
DOI: 10.1038/s41467-018-05614-6
Schumacher, Dagmar: Compensatory mechanisms for methylglyoxal detoxification in experimental & clinical diabetes / Dagmar Schumacher, Jakob Morgenstern, Yoko Oguchi, Nadine Volk, Stefan Kopf, Jan Benedikt Groener, P… , 19 September 2018. - 10 S.
In: Molecular metabolism, ISSN 2212-8778. 18(2018), Seite 143-152
DOI: 10.1016/j.molmet.2018.09.005
Nigro, Cecilia: Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells / Cecilia Nigro, Alessia Leone, Michele Longo, Immacolata Prevenzano, Thomas H. Fleming, Antonella Nic… , 2019. - 13 S.
In: Biochimica et biophysica acta, ISSN 1879-260X. 1865(2019), 1, Seite 73-85
DOI: 10.1016/j.bbadis.2018.10.014
Weigand, Tim: Carnosine catalyzes the formation of the oligo/polymeric products of methylglyoxal / Tim Weigand, Benjamin Singler, Thomas Fleming, Peter Nawroth, Karel D. Klika, Christian Thiel, Hans … , April 05, 2018. - 14 S.
In: Cellular physiology and biochemistry, ISSN 1421-9778. 46(2018), 2, Seite 713-726
DOI: 10.1159/000488727
Sachdeva, Robin: TRPC proteins contribute to development of diabetic retinopathy and regulate glyoxalase 1 activity and methylglyoxal accumulation / Robin Sachdeva, Andrea Schlotterer, Dagmar Schumacher, Christin Matka, Ilka Mathar, Nadine Dietrich,… , 5 January 2018. - 12 S.
In: Molecular metabolism, ISSN 2212-8778. 9(2018), Seite 156-167
DOI: 10.1016/j.molmet.2018.01.003
Sultan, Cheryl Sophia: Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells / Cheryl S. Sultan, Andrea Saackel, Antonia Stank, Thomas Fleming, Maria Fedorova, Ralf Hoffmann, Rebe… , 01 March 2018. - 10 S.
In: Redox Biology, ISSN 2213-2317. 16(2018), Seite 113-122
DOI: 10.1016/j.redox.2018.02.018
Bauer, Rüdiger von: Pleiotropic effect of lipoprotein-apheresis on the soluble form of activated leukocyte cell adhesion molecule (sALCAM) in familial hypercholesterolaemia / Rüdiger von Bauer, Dimitrios Oikonomou, Alba Sulaj, Stefan Kopf, Thomas Fleming, Gottfried Rudofsky,… , June 11, 2018. - 5 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 126(2018), Seite 1-5
DOI: 10.1055/a-0630-0232
Gerst, Felicia: The expression of Aldolase B in islets is negatively associated with insulin secretion in humans / Felicia Gerst, Benjamin A. Jaghutriz, Harald Staiger, Anke M. Schulte, Estela Lorza-Gil, Gabriele Ka… , 07 September 2018. - 11 S.
In: The journal of clinical endocrinology & metabolism, ISSN 1945-7197. 103(2018), 12, Seite 4373-4383
DOI: 10.1210/jc.2018-00791
Kumar, Varun: Purification and characterization of the soluble form of the receptor for advanced glycation end-products (sRAGE) : a novel fast, economical and convenient method / Varun Kumar, Alba Sulaj, Thomas Fleming, Peter P. Nawroth, 19. September 2017. - 7 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 126(2018), 3, Seite 141-147
DOI: 10.1055/s-0043-110478
Wiedenmann, Tanja: Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice / Tanja Wiedenmann, Nadine Dietrich, Thomas Fleming, Sandro Altamura, Leo E. Deelman, Rob H. Henning, … , 2018. - 9 S.
In: Journal of diabetes and its complications, ISSN 1873-460X. 32(2018), 2, Seite 130-138
DOI: 10.1016/j.jdiacomp.2017.11.007
Oikonomou, Dimitrios: Genetic polymorphisms of antioxidant and antiglycation enzymes and diabetic complications : how much can we learn from the genes? / Dimitrios Oikonomou, Jan Benedikt Groener, Ruan Cheko, Zoltan Kender, Lars Kihm, Thomas Fleming, Ste… , 2018. - 7 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 126(2018), 1, Seite 7-13
DOI: 10.1055/s-0043-106442
Kopf, Stefan: Breathlessness and restrictive lung disease : an important diabetes-related feature in patients with type 2 diabetes / Stefan Kopf, Jan B. Groener, Zoltan Kender, Thomas Fleming, Maik Brune, Christin Riedinger, Nadine V… , June 06, 2018. - 12 S.
In: Respiration, ISSN 1423-0356. 96(2018), 1, Seite 29-40
DOI: 10.1159/000488909
Rezende Felipe, Flávia Figueiredo de: The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice / Flávia Rezende, Franziska Moll, Maria Walter, Valeska Helfinger, Fabian Hahner, Patrick Janetzko, Ch… . - 10 S.
In: Redox Biology, ISSN 2213-2317. 15(2018), S. 12-21
DOI: 10.1016/j.redox.2017.11.014
Moraru, Alexandra: Elevated levels of the reactive metabolite methylglyoxal recapitulate progression of type 2 dffiabetes / Alexandra Moraru, Janica Wiederstein, Daniel Pfaff, Thomas Fleming, Aubry K. Miller, Peter Nawroth, … , 15 March 2018. - 17 S.
In: Cell metabolism, ISSN 1932-7420. 27(2018,4) S. 926-934, e1-e8, 17 Seiten
DOI: 10.1016/j.cmet.2018.02.003
Hidmark, Asa S.: Analysis of immune cells in single sciatic nerves and dorsal root ganglion from a single mouse using flow cytometry / Asa S. Hidmark, Peter P. Nawroth, Thomas Fleming, 12/6/2017. - 1 Online-Ressource (1 Videodatei, 12:35 min) : farbig
In: JoVE, ISSN 1940-087X. (2017), 130, Artikel-ID 56538, Seite 1-8
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Mendler, Michael: Reduction in ins-7 gene expression in non-neuronal cells of high glucose exposed Caenorhabditis elegans protects from reactive metabolites, preserves neuronal structure and head motility, and prolongs lifespan / Michael Mendler, Christin Riedinger, Andrea Schlotterer, Nadine Volk, Thomas Fleming, Stephan Herzig… , 2017. - 7 S.
In: Journal of diabetes and its complications, ISSN 1873-460X. 31(2017), 2, Seite 304-310
DOI: 10.1016/j.jdiacomp.2016.09.014
Pfaff, Daniel: Reply to Richarme: Evidence against a role of DJ-1 in methylglyoxal detoxification / Daniel H. Pfaff, Thomas Fleming, Peter Nawroth, and Aurelio A. Teleman, August 4, 2017. - 2 S.
In: The journal of biological chemistry, ISSN 1083-351X. 292(2017), 31, Seite 12784-12785
DOI: 10.1074/jbc.L117.798579
Ziegler, Dan: Association of transketolase polymorphisms with measures of polyneuropathy in patients with recently diagnosed diabetes : Dan Ziegler, Erwin Schleicher, Alexander Strom, Birgit Knebel, Thomas Fleming, Peter Nawroth, Hans‐Ulrich Häring, Nikolaos Papanas, Julia Szendrödi, Karsten Müssig, Hadi Al‐Hasani, Michael Roden, 2017. - 10 S.
In: Diabetes, metabolism research and reviews, ISSN 1520-7560. 33(2017), 4, Seite e2811
DOI: 10.1002/dmrr.2811
Peters, Verena: Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift / Verena Peters, Claus P. Schmitt, Tim Weigand, Kristina Klingbeil, Christian Thiel, Antje van den Ber… , 04 Aug 2017. - 9 S.
In: Journal of enzyme inhibition and medicinal chemistry, ISSN 1475-6374. 32(2017), 1, Seite 1102-1110
DOI: 10.1080/14756366.2017.1355793
Niopek, Katharina: A hepatic GAbp-AMPK axis links inflammatory signaling to systemic vascular damage / Katharina Niopek, Bilgen Ekim Üstünel, Susanne Seitz, Minako Sakurai, Annika Zota, Frits Mattijssen,… , August 8, 2017. - 13 S.
In: Cell reports, ISSN 2211-1247. 20(2017), 6, Seite 1422-1434
DOI: 10.1016/j.celrep.2017.07.023
Billeter, Adrian: Gastric bypass simultaneously improves adipose tissue function and insulin-dependent type 2 diabetes mellitus / Adrian T. Billeter, Spiros Vittas, Barbara Israel, Katharina M. Scheurlen, Asa Hidmark, Thomas H. Fl… , 9 July 2017. - 10 S.
In: Langenbeck's archives of surgery, ISSN 1435-2451. 402(2017), 6, Seite 901-910
DOI: 10.1007/s00423-017-1601-x
Zemva, Johanna: Hormesis enables cells to handle accumulating toxic metabolites during increased energy flux / Johanna Zemva, Christoph Andreas Fink, Thomas Henry Fleming, Leonard Schmidt, Anne Loft, Stephan Her… , 12 August 2017. - 13 S.
In: Redox Biology, ISSN 2213-2317. 13(2017), Seite 674-686
DOI: 10.1016/j.redox.2017.08.007
Brings, Sebastian: Dicarbonyls and advanced glycation end-products in the development of diabetic complications and targets for intervention / Sebastian Brings, Thomas Fleming, Marc Freichel, Martina U. Muckenthaler, Stephan Herzig and Peter P…
In: International journal of molecular sciences, ISSN 1422-0067. 18(2017,5) Artikel-Nummer 984, 24 Seiten
DOI: 10.3390/ijms18050984
Brings, Sebastian: A scavenger peptide prevents methylglyoxal induced pain in mice / Sebastian Brings, Thomas Fleming, Svenja De Buhr, Barbro Beijer, Thomas Lindner, Artjom Wischnjow, Z… , 2017. - 9 S.
In: Biochimica et biophysica acta, ISSN 1879-260X. 1863(2017), 3, Seite 654-662
DOI: 10.1016/j.bbadis.2016.12.001
Brenner, Thorsten: Soluble TREM-1 as a diagnostic and prognostic biomarker in patients with septic shock : an observational clinical study / Thorsten Brenner, Florian Uhle, Thomas Fleming, Matthias Wieland, Thomas Schmoch, Felix Schmitt, Kar… , 2017. - 7 S.
In: Biomarkers, ISSN 1366-5804. 22(2017), 1, Seite 63-69
DOI: 10.1080/1354750X.2016.1204005
Kynast, Katharina: Diabetes-associated biobanking : more topical than ever? / Katharina Lydia Kynast, Nadine Volk, Thomas Fleming, Esther Herpel, 19. September 2017. - 7 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 125(2017), 9, Seite 603-609
DOI: 10.1055/s-0042-123039
Gao, Yuanqing: Dietary sugars, not lipids, drive hypothalamic inflammation / Yuanqing Gao, Maximilian Bielohuby, Thomas Fleming, Gernot F. Grabner, Ewout Foppen, Wagner Bernhard… . - 12 S.
In: Molecular metabolism, ISSN 2212-8778. 6(2017), 8, S. 897-908
DOI: 10.1016/j.molmet.2017.06.008
Hidmark, Asa S.: Electrical muscle stimulation induces an increase of VEGFR2 on circulating hematopoietic stem cells in patients with diabetes / Asa Hidmark, PhD, Ioannis Spanidis, Thomas H. Fleming, PhD, Nadine Volk, PhD, Volker Eckstein, PhD, … , 2017. - 15 S.
In: Clinical therapeutics, ISSN 1879-114X. 39(2017), 6, Seite 1132-1144e.2
DOI: 10.1016/j.clinthera.2017.05.340
Hidmark, Asa S.: STZ causes depletion of immune cells in sciatic nerve and dorsal root ganglion in experimental diabetes / Asa S. Hidmark, Peter P. Nawroth, Thomas Fleming. - 7 S.
In: Journal of neuroimmunology, ISSN 1872-8421. 306(2017), S. 76-82
DOI: 10.1016/j.jneuroim.2017.03.008
Sulaj, Alba: ALCAM a novel biomarker in patients with type 2 diabetes mellitus complicated with diabetic nephropathy / Alba Sulaj, Stefan Kopf, Elisabeth Gröne, Hermann-Josef Gröne, Sigrid Hoffmann, Erwin Schleicher, Ha… , 2017. - 8 S.
In: Journal of diabetes and its complications, ISSN 1873-460X. 31(2017), 6, Seite 1058-1065
DOI: 10.1016/j.jdiacomp.2017.01.002
Morgenstern, Jakob: Sensitive mass spectrometric assay for determination of 15-deoxy-Δ12,14-prostaglandin J2 and its application in human plasma samples of patients with diabetes / Jakob Morgenstern, Thomas Fleming, Ivelina Kadiyska, Sebastian Brings, Jan Benedikt Groener, Peter N… , 2018. - 8 S.
In: Analytical and bioanalytical chemistry, ISSN 1618-2650. 410(2018), 2, Seite 521-528
DOI: 10.1007/s00216-017-0748-1
Reichert, Olga: Impaired glyoxalase activity is associated with reduced expression of neurotrophic factors and pro-inflammatory processes in diabetic skin cells / Olga Reichert, Thomas Fleming, Gitta Neufang, Martin Schmelz, Harald Genth, Volkhard Kaever, Horst W… , 2017. - 7 S.
In: Experimental dermatology, ISSN 1600-0625. 26(2017), 1, Seite 44-50
DOI: 10.1111/exd.13118
Kumar, Varun: Homeostatic nuclear RAGE-ATM interaction is essential for efficient DNA repair / Varun Kumar, Thomas Fleming, Stefan Terjung, Christian Gorzelanny, Christoffer Gebhardt, Raman Agraw… , 09 August 2017. - 19 S.
In: Nucleic acids research, ISSN 1362-4962. 45(2017), 18, Seite 10595-10613
DOI: 10.1093/nar/gkx705
Kreycy, Nele: Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma / Nele Kreycy; Christiane Gotzian; Thomas Fleming; Christa Flechtenmacher; Niels Grabe; Peter Plinkert… . -
London; Berlin; Heidelberg: BioMed Central; Springer, 2017. - 1 Online-Ressource
Kreycy, Nele: Glyoxalase 1 expression is associated with an unfavorable prognosis of oropharyngeal squamous cell carcinoma / Nele Kreycy, Christiane Gotzian, Thomas Fleming, Christa Flechtenmacher, Niels Grabe, Peter Plinkert… , 26 May 2017
In: BMC cancer, ISSN 1471-2407. 17(2017) Artikel-Nummer 382, 9 Seiten
DOI: 10.1186/s12885-017-3367-5
Schmoch, Thomas: The glyoxalase system and methylglyoxal-derived carbonyl stress in sepsis : glycotoxic aspects of sepsis pathophysiology / Thomas Schmoch, Florian Uhle, Benedikt H. Siegler, Thomas Fleming, Jakob Morgenstern, Peter P. Nawro… , 17 March 2017
In: International journal of molecular sciences, ISSN 1422-0067. 18(2017,3) Artikel-Nummer 657, 19 Seiten
DOI: 10.3390/ijms18030657
Peters, Andreas: Reduced glyoxalase 1 activity in carotid artery plaques of nondiabetic patients with increased hemoglobin A1c level / Andreas S. Peters, Marieluise Lercher, Thomas H. Fleming, Peter P. Nawroth, Moritz S. Bischoff, Susa… , October 2016. - 5 S.
In: Journal of vascular surgery, ISSN 1097-6809. 64(2016), 4, Seite 990-994
DOI: 10.1016/j.jvs.2016.04.025
Khan, Mahtab A.: Hyperglycemia in stroke impairs polarization of monocytes/macrophages to a protective noninflammatory cell type / Mahtab A. Khan, Sina Schultz, Alaa Othman, Thomas Fleming, Rafael Lebrón-Galán, Dirk Rades, Diego Cl… , September 7, 2016. - 13 S. : Illustrationen
In: The journal of neuroscience, ISSN 1529-2401. 36(2016), 36, Seite 9313-9325
DOI: 10.1523/JNEUROSCI.0473-16.2016
Jensen, Troels Mygind: Methylglyoxal is associated with changes in kidney function among individuals with screen-detected Type 2 diabetes mellitus / T.M. Jensen, D. Vistisen, T. Fleming, P.P. Nawroth, P. Rossing, M.E. Jørgensen, T. Lauritzen, A. San… , [2016]. - 7 S.
In: Diabetic medicine, ISSN 1464-5491. 33(2016), 12, Seite 1625-1631
DOI: 10.1111/dme.13201
Betzen, Christian: Shiga toxin 2a-induced endothelial injury in hemolytic uremic syndrome : a metabolomic analysis / Christian Betzen, Kathrin Plotnicki, Farnoosh Fathalizadeh, Kirk Pappan, Thomas Fleming, Martina Bie… , 2016. - 10 S.
In: The journal of infectious diseases, ISSN 1537-6613. 213(2016), 6, Seite 1031-1040
DOI: 10.1093/infdis/jiv540
Hofer, Stefan: RAGE-mediated inflammation in patients with septic shock / Stefan Hofer, MD, Florian Uhle, PhD, Thomas Fleming, PhD, Christian Hell, MD, Thomas Schmoch, MD, Th… , 20 January 2016. - 13 S.
In: Journal of surgical research, ISSN 1095-8673. 202(2016), 2, Seite 315-327
DOI: 10.1016/j.jss.2016.01.019
Dietrich, Nadine: The DPP4 inhibitor linagliptin protects from experimental diabetic retinopathy / Nadine Dietrich, Matthias Kolibabka, Stephanie Busch, Petra Bugert, Ulrike Kaiser, Jihong Lin, Thoma… , December 12, 2016. - 17 S.
In: PLOS ONE, ISSN 1932-6203. 11(2016,12) Artikel-Nummer e0167853, 17 Seiten
DOI: 10.1371/journal.pone.0167853
Kolibabka, Matthias: Dicarbonyl stress mimics diabetic neurovascular damage in the retina / M. Kolibabka, P. Friedrichs, N. Dietrich, T. Fleming, A. Schlotterer, H.-P. Hammes, 24 May 2016. - 6 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 124(2016), 7, Seite 437-439
DOI: 10.1055/s-0042-106081
Pfaff, Daniel: Evidence against a role for the parkinsonism-associated protein DJ-1 in methylglyoxal detoxification / Daniel H. Pfaff, Thomas Fleming, Peter Nawroth and Aurelio A. Teleman, 2017. - 6 S.
In: The journal of biological chemistry, ISSN 1083-351X. 292(2017), 2, Seite 685-690
DOI: 10.1074/jbc.M116.743823
Morgenstern, Jakob: Loss of glyoxalase 1 induces compensatory mechanism to achieve dicarbonyl detoxification in mammalian schwann cells / Jakob Morgenstern, Thomas Fleming, Dagmar Schumacher, Volker Eckstein, Marc Freichel, Stephan Herzig… , 2017. - 15 S.
In: The journal of biological chemistry, ISSN 1083-351X. 292(2017), 8, Seite 3224-3238
DOI: 10.1074/jbc.M116.760132
Ejdesjö, Andreas: Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy / Andreas Ejdesjö, Sebastian Brings, Thomas Fleming, Rikard G. Fred, Peter P. Nawroth, Ulf J. Eriksson. - 9 S.
In: Reproductive toxicology, ISSN 1873-1708. 62(2016), S. 62-70
DOI: 10.1016/j.reprotox.2016.04.015
Hernández Hidalgo, Itahisa: Characterization of aggregate load and pattern in living yeast cells by flow cytometry / Itahisa Hernández Hidalgo, Thomas Fleming, Volker Eckstein, Stephan Herzig, Peter P. Nawroth, Jens T… , 1 September 2016. - 12 S.
In: BioTechniques, ISSN 1940-9818. 61(2016), 3, Seite 137-148
DOI: 10.2144/000114452
Üstünel, Bilgen Ekim: Control of diabetic hyperglycaemia and insulin resistance through TSC22D4 / Bilgen Ekim Üstünel, Kilian Friedrich, Adriano Maida, Xiaoyue Wang, Anja Krones-Herzig, Oksana Seibe… , 09 November 2016. - 11 S.
In: Nature Communications, ISSN 2041-1723. 7(2016) Artikel-Nummer 13267, 11 Seiten
DOI: 10.1038/ncomms13267
Sulaj, Alba: The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule / Alba Sulaj, Johanna Zemva, Ulrike Zech, Annika Wöhning, Maik Brune, Gottfried Rudofsky, Peter P. Naw… , 13 October 2016
In: BMC endocrine disorders, ISSN 1472-6823. 16(2016) Artikel-Nummer 56, 7 Seiten
DOI: 10.1186/s12902-016-0138-2
Sulaj, Alba: The effect of lifestyle intervention in obesity on the soluble form of activated leukocyte cell adhesion molecule / Alba Sulaj; Johanna Zemva; Ulrike Zech; Annika Wöhning; Maik Brune; Gottfried Rudofsky; Peter P. Naw… . -
London: BioMed Central, 2016. - 1 Online-Ressource
DOI: 10.1186/s12902-016-0138-2
Müller-Krebs, Sandra: Effect of benfotiamine in podocyte damage induced by peritoneal dialysis fluid / Sandra Müller-Krebs, Katharina Nissle, Julia Tsobaneli, Martin Zeier, Lars Philipp Kihm, Zoltan Kend… , 10 March 2015. - 7 S.
In: Frontiers in medicine, ISSN 2296-858X. 2(2015), Artikel-ID 10, Seite 1-7
DOI: 10.3389/fmed.2015.00010
Wortmann, Markus: A Glyoxalase-1 knockdown does not have major short term effects on energy expenditure and atherosclerosis in mice / Markus Wortmann, Maani Hakimi, Thomas Fleming, Andreas S. Peters, Tjeerd P. Sijmonsma, Stephan Herzi… , 2016
In: Journal of diabetes research, ISSN 2314-6753. (2016) Artikel-Nummer 2981639, 8 Seiten
DOI: 10.1155/2016/2981639
Peters, Verena: Carnosine metabolism in diabetes is altered by reactive metabolites / Verena Peters · Barbara Lanthaler · Albert Amberger · Thomas Fleming · Elisabete Forsberg · Markus H… , 17 June 2015. - 10 S.
In: Amino acids, ISSN 1438-2199. 47(2015), 11, Seite 2367-2376
DOI: 10.1007/s00726-015-2024-z
Parčina, Marijo: No short-term effects of calorie-controlled Mediterranean or fast food dietary interventions on established biomarkers of vascular or metabolic risk in healthy individuals / Marijo Parcina, Maik Brune, Vareska Kaese, Markus Zorn, Rainer Spiegel, Valerija Vojvoda, Thomas Fle… , 2015. - 9 S.
In: Nutrition research and practice, ISSN 2005-6168. 9(2015), 2, Seite 165-173
DOI: 10.4162/nrp.2015.9.2.165
Liesz, Arthur: DAMP signaling is a key pathway inducing immune modulation after brain injury / Arthur Liesz, Alexander Dalpke, Eva Mracsko, Stefan Roth, Wei Zhou, Huan Yang, Shin-Young Na, Mustaf… , January 14, 2015. - 14 S.
In: The journal of neuroscience, ISSN 1529-2401. 35(2015), 2, Seite 583-596
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Seidensaal, Katharina: Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma / Katharina Seidensaal, Andre Nollert, Agnes Hiou Feige, Marie Muller, Thomas Fleming, Nikolas Gunkel,… , 3 December 2015. - 13 S.
In: Molecular cancer, ISSN 1476-4598. 14(2015), Artikel-ID 204, Seite 1-13
DOI: 10.1186/s12943-015-0476-0
Mendler, Michael: daf-16/FOXO and glod-4/glyoxalase-1 are required for the life-prolonging effect of human insulin under high glucose conditions in Caenorhabditis elegans / Michael Mendler, Andreas Schlotterer, Youssef Ibrahim, Georgi Kukudov, Thomas Fleming, Angelika Bier… , 2015. - 9 S.
In: Diabetologia, ISSN 1432-0428. 58(2015), 2, Seite 393-401
DOI: 10.1007/s00125-014-3415-5
Mcvicar, Carmel: Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice / Carmel M. McVicar, Micheal Ward, Liza M. Colhoun, Jasenka Guduric-Fuchs, Angelika Bierhaus, Thomas F… , 17 February 2015. - 9 S.
In: Diabetologia, ISSN 1432-0428. 58(2015), 5, Seite 1129-1137
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Jensen, Troels Mygind: Impact of intensive treatment on serum methylglyoxal levels among individuals with screen-detected type 2 diabetes : the ADDITION-Denmark study / Troels M. Jensen, Dorte Vistisen, Thomas Fleming, Peter P. Nawroth, Marit E. Jørgensen, Torsten Laur… , 27 March 2015. - 8 S.
In: Acta diabetologica, ISSN 1432-5233. 52(2015), 5, Seite 929-936
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Meister, Michael: Dickkopf-3, a tissue-derived modulator of local T-cell responses / Michael Meister, Maria Papatriantafyllou, Viola Nordström, Varun Kumar, Julia Ludwig, Kathy O. Lui, … , 24 February 2015. - 13 S.
In: Frontiers in immunology, ISSN 1664-3224. 6(2015), Artikel-ID 78, Seite 1-13
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Jörgens, Kristina: High tissue glucose alters intersomitic blood vessels in zebrafish via methylglyoxal targeting the VEGF receptor signaling cascade / Kristina Jörgens, Sandra J. Stoll, Jennifer Pohl, Thomas H. Fleming, Carsten Sticht, Peter P. Nawrot… , January 2015. - 13 S.
In: Diabetes, ISSN 1939-327X. 64(2015), 1, Seite 213-225
DOI: 10.2337/db14-0352
Hansen, Christain, Stevns: The role of serum methylglyoxal on diabetic peripheral and cardiovascular autonomic neuropathy : the ADDITION Denmark study / C.S. Hansen, T.M. Jensen, J.S. Jensen, P. Nawroth, T. Fleming, D.R. Witte, T. Lauritzen, A. Sandbæk,… , 10 March 2015. - 8 S.
In: Diabetic medicine, ISSN 1464-5491. 32(2015), 6, Seite 778-785
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Uhle, Florian: Role of the RAGE axis during the immune response after severe trauma : a prospective pilot study / Florian Uhle, Christoph Lichtenstern,Thorsten Brenner,Thomas Fleming, Christian Koch, Andreas Hecker… , 9 December 2015. - 9 S.
In: Mediators of inflammation, ISSN 1466-1861. (2015) Article ID 691491, 9 pages
DOI: 10.1155/2015/691491
Gröner, Jan: Group singing as a therapy during diabetes training : a randomized controlled pilot study / J.B. Groener, I. Neus, S. Kopf, M. Hartmann, J. Schanz, E. Kliemank, B. Wetekam, L. Kihm, T. Fleming… , November 2015. - 5 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 123(2015), 10, Seite 617-621
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Seidensaal, Katharina: Impaired aldehyde dehydrogenase 1 subfamily member 2A-dependent retinoic acid signaling is related with a mesenchymal-like phenotype and an unfavorable prognosis of head and neck squamous cell carcinoma / Katharina Seidensaal; Andre Nollert; Agnes Hiou Feige; Marie Muller; Thomas Fleming; Nikolas Gunkel;… . -
London: BioMed Central, 2015. - 1 Online-Ressource
Kender, Zoltán: Effect of metformin on methylglyoxal metabolism in patients with type 2 diabetes / Z. Kender, T. Fleming, S. Kopf, P. Torzsa, V. Grolmusz, S. Herzig, E. Schleicher, K. Rácz, P. Reisma… , 07. April 2014. - 4 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 122(2014), 5, Seite 316-319
DOI: 10.1055/s-0034-1371818
Hidmark, Asa S.: A new paradigm to understand and treat diabetic neuropathy / A. Hidmark, T. Fleming, S. Vittas, M. Mendler, D. Deshpande, J.B. Groener, B.P. Müller, P.W. Reeh, S… , 12. März 2014. - 7 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 226(2014), 4, Seite 201-207
DOI: 10.1055/s-0034-1367023
Müller, Beat P.: Nitrosative stress but not glycemic parameters correlate with improved neuropathy in nonseverely obese diabetic patients after Roux-Y gastric bypass / Beat P. Müller-Stich, Adrian T. Billeter, Thomas Fleming, Lars Fischer, Markus W. Büchler, Peter P. … , 2015. - 8 S.
In: Surgery for obesity and related diseases, ISSN 1878-7533. 11(2015), 4, Seite 847-854
DOI: 10.1016/j.soard.2014.12.007
Peters, Andreas: Gender difference in glyoxalase 1 activity of atherosclerotic carotid artery lesions / Andreas S. Peters, MD, Maani Hakimi, MD, Spiros Vittas, PhD, Thomas H. Fleming, PhD, Peter P. Nawrot… , 2015. - 6 S.
In: Journal of vascular surgery, ISSN 1097-6809. 62(2015), 2, Seite 471-476
DOI: 10.1016/j.jvs.2014.02.058
Kihm, Lars Philipp: Increased peritoneal damage in glyoxalase 1 knock-down mice treated with peritoneal dialysis / Lars P. Kihm, Sandra Müller-Krebs, Sandra Holoch, Svenja Schmuck, Luis E. Becker, Michael Brownlee, … , 2015. - 9 S.
In: Nephrology, dialysis, transplantation, ISSN 1460-2385. 30(2015), 3, Seite 401-409
DOI: 10.1093/ndt/gfu346
Nawroth, Peter Paul: Diabetic complications : a disease of reactive metabolites / Peter Paul Nawroth, Stefan Herzig, and Thomas Fleming, 2014. - 8 S. : Ill.
In: Vision and diabetes. (2014), Seite 99-106
Nigro, Cecilia: Methylglyoxal impairs endothelial insulin sensitivity both in vitro and in vivo / Cecilia Nigro, Gregory A. Raciti, Alessia Leone, Thomas H. Fleming, Michele Longo, Immacolata Preven… . - 10 S.
In: Diabetologia, ISSN 1432-0428. 57(2014), 7, S. 1485-1494
DOI: 10.1007/s00125-014-3243-7
Fleming, Thomas: Reactive metabolites as a cause of late diabetic complications / Thomas Fleming, Peter P. Nawroth. - 4 S.
In: Biochemical Society transactions, ISSN 1470-8752. 42(2014), 2, S. 439-442
DOI: 10.1042/BST20130265
Wang, Jing: CD74 indicates microglial activation in experimental diabetic retinopathy and exogenous methylglyoxal mimics the response in normoglycemic retina / Jing Wang, Jihong Lin, Andreas Schlotterer, Liang Wu, Thomas Fleming, Stephanie Busch, Nadine Dietri… , 2014. - 9 S.
In: Acta diabetologica, ISSN 1432-5233. 51(2014), 5, Seite 813-821
DOI: 10.1007/s00592-014-0616-9
Kiefer, Autumn S.: Methylglyoxal concentrations differ in standard and washed neonatal packed red blood cells / Autumn S. Kiefer, Thomas Fleming, George J. Eckert, Brenda B. Poindexter, Peter P. Nawroth & Mervin … . - 6 S.
In: Pediatric research, ISSN 1530-0447. 75(2014), 3, S. 409-414
DOI: 10.1038/pr.2013.243
Müller, Beat P.: Gastric bypass leads to improvement of diabetic neuropathy independent of glucose normalization : results of a prospective cohort study (DiaSurg 1 study) / Beat P. Müller-Stich, MD, Lars Fischer, MD, Hannes G. Kenngott, MD, Matthias Gondan, PhD, Jonas Senf… , November 2013. - 7 S.
In: Annals of surgery, ISSN 1528-1140. 258(2013), 5, Seite 760-766
DOI: 10.1097/SLA.0b013e3182a618b2
Gröner, Jan: C332C genotype of glyoxalase 1 and its association with late diabetic complications : Glo1 genotype and diabetic neuropathy / J.B. Groener, P. Reismann, T. Fleming, H. Kalscheuer, D. Lehnhoff, A. Hamann, P. Roser, A. Bierhaus,… , 17. Juni 2013. - 4 S.
In: Experimental and clinical endocrinology & diabetes, ISSN 1439-3646. 121(2013), 7, Seite 436-439
DOI: 10.1055/s-0033-1345124
Brenner, Thorsten: Reactive metabolites and AGE-RAGE-mediated inflammation in patients following liver transplantation / Thorsten Brenner, Thomas H. Fleming, David Spranz, Peter Schemmer, Thomas Bruckner, Florian Uhle, Ei… , 22 May 2013. - 10 S.
In: Mediators of inflammation, ISSN 1466-1861. (2013), Seite 1-10
DOI: 10.1155/2013/501430
Andersson, David A.: Methylglyoxal evokes pain by stimulating TRPA1 / David A. Andersson, Clive Gentry, Emily Light, Nisha Vastani, Julie Vallortigara, Angelika Bierhaus,… , October 22, 2013. - 9 S.
In: PLOS ONE, ISSN 1932-6203. 8(2013,10) Artikel-Nummer e77986, 9 Seiten
DOI: 10.1371/journal.pone.0077986
Wallmeier, Dirk: Genetic modulation of the serotonergic pathway : influence on weight reduction and weight maintenance / Dirk Wallmeier, Julia K. Winkler, Thomas Fleming, Annika Woehning, Katharina Huennemeyer, Eva Roeder… , 25 June 2013. - 10 S.
In: Genes & nutrition, ISSN 1865-3499. 8(2013), 6, Seite 601-610
DOI: 10.1007/s12263-013-0350-x
Fleming, Thomas: Aging-dependent reduction in glyoxalase 1 delays wound healing / Fleming, Thomas H.; Theilen, Till-Martin ... Bierhaus, Angelika ... Kroll, Jens ... Nawrotzki, Ralph… , 2013. - 11 S.
In: Gerontology, ISSN 0304-324X. 59(2013), 5, Seite 427-437
Fleming, Thomas: The role of the glyoxalase system & reactive metabolites in the aging process / vorgelegt von Thomas Henry Fleming, 2012 [ersch.] 2013. - 111 Bl. : Ill., graph. Darst.
Fleming, Thomas: Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? / T. Fleming, J. Cuny, G. Nawroth, Z. Djuric, P.M. Humpert, M. Zeier, A. Bierhaus, P.P. Nawroth, 22 January 2012. - 5 S.
In: Diabetologia, ISSN 1432-0428. 55(2012), 4, Seite 1151-1155
DOI: 10.1007/s00125-012-2452-1
Bierhaus, Angelika: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy / Angelika Bierhaus, Thomas Fleming, Stoyan Stoyanov, Andreas Leffler, Alexandru Babes, Cristian Neacs… , 06 July 2012. - 8 S.
In: Nature medicine, ISSN 1546-170X. 18(2012), 6, Seite 926-933
DOI: 10.1038/nm.2750
Brenner, Thorsten: L-arginine and asymmetric dimethylarginine are early predictors for survival in septic patients with acute liver failure / Thorsten Brenner, Thomas H. Fleming, Claudia Rosenhagen, Ute Krauser, Markus Mieth, Thomas Bruckner,… , 2012. - 11 S.
In: Mediators of inflammation, ISSN 1466-1861. (2012), Artikel-Nummer 210454, 11 Seiten
DOI: 10.1155/2012/210454
Djuric, Zdenka: Targeting activation of specific NF-[kappa]B subunits prevents stress-dependent atherothrombotic gene expression / Zdenka Djuric, Muhammed Kashif, Thomas Fleming, Sajjad Muhammad, David Piel, Rüdiger von Bauer, Flor… , 2012 Oct 23. - 12 S.
In: Molecular medicine, ISSN 1528-3658. 18(2012), 1, Seite 1375-1386
DOI: 10.2119/molmed.2012.00282
Rudofsky, Gottfried: Identical LDL-cholesterol lowering but non-identical effects on NF-[kappa]B activity : High dose simvastatin vs combination therapy with ezetimibe. / Gottfried Rudofsky, Peter Reismann, Jan B. Groener, Zdenka Djuric, Thomas Fleming, Cornelia Metzner,… , July 2012. - 7 S.
In: Atherosclerosis, ISSN 1879-1484. 223(2012), 1, Seite 190-196
DOI: 10.1016/j.atherosclerosis.2012.04.003
Fleming, Thomas: Reactive metabolites and AGE/RAGE-Mediated cellular dysfunction affect the aging process : a mini-review / Thomas H. Fleming, Per M. Humpert, Peter P. Nawroth, Angelika Bierhaus, 2011. - 9 S.
In: Gerontology, ISSN 1423-0003. 57(2011), 5 vom: Aug., Seite 435-443
DOI: 10.1159/000322087

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