
Eils, Roland Prof. Dr.Universität HeidelbergHeidelberg
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Publications in heiBIB 
- Steinfeldt, Jakob: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats / Jakob Steinfeldt, Benjamin Wild, Thore Buergel, Maik Pietzner, Julius Upmeier zu Belzen, Andre Vauve… , 2025. - 15 S. : Illustrationen, Diagramme
In: Nature Communications, ISSN 2041-1723. 16(2025), Artikel-ID 585, Seite 1-15
DOI: 10.1038/s41467-025-55879-x
- Müller-Bötticher, Niklas: Sainsc : a computational tool for segmentation-free analysis of in situ capture data / Niklas Müller-Bötticher, Sebastian Tiesmeyer, Roland Eils, and Naveed Ishaque. - Online version of record before inclusion in an issue, 12 November 2024. - 11 S. : Illustrationen
In: Small Methods, ISSN 2366-9608. (2024), Artikel-ID 2401123, Seite 1-11
DOI: 10.1002/smtd.202401123
- Heumos, Lukas: An open-source framework for end-to-end analysis of electronic health record data / Lukas Heumos, Philipp Ehmele, Tim Treis, Julius Upmeier zu Belzen, Eljas Roellin, Lilly May, Altana … , 12 September 2024. - 12 S. : Illustrationen
In: Nature medicine, ISSN 1546-170X. 30(2024), 11, Seite 3369-3380
DOI: 10.1038/s41591-024-03214-0
- Steinfeldt, Jakob: Retracted article: Medical history predicts phenome-wide disease onset and enables the rapid response to emerging health threats / Jakob Steinfeldt, Benjamin Wild, Thore Buergel, Maik Pietzner, Julius Upmeier zu Belzen, Andre Vauve… , 2024. - 1 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 4257, Seite 1
DOI: 10.1038/s41467-024-48568-8
- Loske, Jennifer: Pharmacological improvement of cystic fibrosis transmembrane conductance regulator function rescues airway epithelial homeostasis and host defense in children with cystic fibrosis / Jennifer Loske, Mirjam Völler, Sören Lukassen, Mirjam Stahl, Loreen Thürmann, Anke Seegebarth, Jobst… , June 1, 2024. - 13 S. : Illustrationen
In: American journal of respiratory and critical care medicine, ISSN 1535-4970. 209(2024), 11 vom: Juni, Seite 1338-1350
DOI: 10.1164/rccm.202310-1836OC
- Semler, Sebastian Claudius: Die Medizininformatik-Initiative im Überblick - Aufbau einer Gesundheitsforschungsdateninfrastruktur in Deutschland / Sebastian C. Semler, Martin Boeker, Roland Eils, Dagmar Krefting, Markus Loeffler, Jens Bussmann, Fr… , 5. Juni 2024. - 13 S. : Illustrationen
In: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz, ISSN 1437-1588. 67(2024), 6, Seite 616-628
DOI: 10.1007/s00103-024-03887-5
- Peng, Zhuoxin: Directed acyclic graph for epidemiological studies in childhood food allergy : construction, user's guide, and application / Zhuoxin Peng, Christian Apfelbacher, Susanne Brandstetter, Roland Eils, Michael Kabesch, Irina Lehm… , 2024
In: Allergy, ISSN 1398-9995. 79(2024), 8, Seite 2051-2064
DOI: 10.1111/all.16025
- Zapatka, Marc: Author correction : The landscape of viral associations in human cancers / Marc Zapatka, Ivan Borozan, Daniel S. Brewer, Murat Iskar, Adam Grundhoff, Malik Alawi, Nikita Desai… , 21 March 2023. - 1 S.
In: Nature genetics, ISSN 1546-1718. 55(2023), 6, Seite 1077-1077
DOI: 10.1038/s41588-023-01316-y
- Kohler, Severin: Eos and OMOCL : towards a seamless integration of openEHR records into the OMOP Common Data Model / Severin Kohler, Diego Boscá, Florian Kärcher, Birger Haarbrandt, Manuel Prinz, Michael Marschollek, … , 24 July 2023. - 22 S. : Illustrationen
In: Journal of biomedical informatics, ISSN 1532-0480. 144(2023) vom: Aug., Artikel-ID 104437, Seite 1-22
DOI: 10.1016/j.jbi.2023.104437
- Gonçalves Magalhães, Vladimir: Immune-epithelial cell cross‐talk enhances antiviral responsiveness to SARS‐CoV‐2 in children / Vladimir G Magalhães, Sören Lukassen, Maike Drechsler, Jennifer Loske, Sandy S Burkart, Sandra Wüst,… , December 06, 2023. - 20 S. : Illustrationen
In: EMBO reports, ISSN 1469-3178. 24(2023), 12 vom: Dez., Artikel-ID e57912, Seite 1-20
DOI: 10.15252/embr.202357912
- Adam, Lukas: Transcriptomics-inferred dynamics of SARS-CoV-2 interactions with host epithelial cells / Lukas Adam, Megan Stanifer, Fabian Springer, Jan Mathony, Maik Brune, Chiara Di Ponzio, Roland Eils,… , 26 Sep 2023. - ?
In: Science signaling, ISSN 1937-9145. 16(2023), 804, Artikel-ID eabl8266, Seite ?
DOI: 10.1126/scisignal.abl8266
- Messingschlager, Marey: Genome-wide DNA methylation sequencing identifies epigenetic perturbations in the upper airways under long-term exposure to moderate levels of ambient air pollution / Marey Messingschlager, Martina Bartel-Steinbach, Sebastian D. Mackowiak, Johanna Denkena, Matthias B… , 15 September 2023. - 14 S.
In: Environmental research, ISSN 1096-0953. 233(2023) vom: Sept., Artikel-ID 116413, Seite 1-14
DOI: 10.1016/j.envres.2023.116413
- Eils, Roland: Schlussbericht für das Projekt de.NBI - Etablierungsphase - Universität Heidelberg - HD-HuB : Berichtszeitraum: 01.03.2015-31.12.2021 / Universität Heidelberg, Heidelberg Center for Human Bioinformatics (HD-HuB) ; Projektleiter: Prof. D… . -
Heidelberg: Universität Heidelberg, [2022?]. - 1 Online-Ressource (16 Seiten, 729,69 KB) : Illustration
DOI: 10.2314/KXP:1884890156
- Klein, Philipp: Temporal control of the integrated stress response by a stochastic molecular switch / Philipp Klein, Stefan M. Kallenberger, Hanna Roth, Karsten Roth, Thi Bach Nga Ly-Hartig, Vera Magg, … , 22 Mar 2022. - 21 S.
In: Science advances, ISSN 2375-2548. 8(2022), 12, Artikel-ID eabk2022, Seite 1-21
DOI: 10.1126/sciadv.abk2022
- Schuth, Sebastian: Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system / Sebastian Schuth, Solange Le Blanc, Teresa G. Krieger, Julia Jabs, Miriam Schenk, Nathalia A. Giese,… , 22 October 2022. - 14 S.
In: Journal of experimental & clinical cancer research, ISSN 1756-9966. 41(2022), Artikel-ID 312, Seite 1-14
DOI: 10.1186/s13046-022-02519-7
- Pietzner, Maik: ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19 / Maik Pietzner, Robert Lorenz Chua, Eleanor Wheeler, Katharina Jechow, Julian D. S. Willett, Helena R… , 15 August 2022. - 15 S. : Illustrationen, Diagramme
In: Nature Communications, ISSN 2041-1723. 13(2022), Artikel-ID 4484, Seite 1-15
DOI: 10.1038/s41467-022-31999-6
- Trefzer, Timo: Intratumoral heterogeneity and immune modulation in lung adenocarcinoma in female smokers and never smokers / Timo B. Trefzer, Marc A. Schneider, Katharina Jechow, Robert Lorenz Chua, Thomas Muley, Hauke Winter… , September 02, 2022. - 14 S. : Illustrationne
In: Cancer research, ISSN 1538-7445. 82(2022), 17, Seite 3116-3129
DOI: 10.1158/0008-5472.CAN-21-3836
- Steinfeldt, Jakob: Neural network-based integration of polygenic and clinical information : development and validation of a prediction model for 10-year risk of major adverse cardiac events in the UK Biobank cohort / Jakob Steinfeldt, Thore Buergel, Lukas Loock, Paul Kittner, Greg Ruyoga, Julius Upmeier zu Belzen, S… , 25 January 2022. - 11 S.
In: The lancet, ISSN 2589-7500. 4(2022,2) Seiten e84-e94, 11 Seiten
DOI: 10.1016/S2589-7500(21)00249-1
- Sunami, Yoshiaki: Single cell analysis of cultivated fibroblasts from chronic pancreatitis and pancreatic cancer patients / Yoshiaki Sunami, Yijun Chen, Bogusz Trojanowicz, Matthias Sommerer, Monika Hämmerle, Roland Eils and… , 19 August 2022. - 32 S. : Illustrationen, Diagramme
In: Cells, ISSN 2073-4409. 11(2022), 16, Artikel-ID 2583, Seite 1-32
DOI: 10.3390/cells11162583
- Radke, Josefine: The genomic and transcriptional landscape of primary central nervous system lymphoma / Josefine Radke, Naveed Ishaque, Randi Koll, Zuguang Gu, Elisa Schumann, Lina Sieverling, Sebastian U… , 10 May 2022. - 20 S.
In: Nature Communications, ISSN 2041-1723. 13(2022), Artikel-ID 2558, Seite 1-20
DOI: 10.1038/s41467-022-30050-y
- Tiesmeyer, Sebastian: SSAM-lite: a light-weight web app for rapid analysis of spatially resolved transcriptomics data / Sebastian Tiesmeyer, Shashwat Sahay, Niklas Müller-Bötticher, Roland Eils, Sebastian D. Mackowiak an… , 28 February 2022. - 7 S.
In: Frontiers in genetics, ISSN 1664-8021. 13(2022) vom: Feb., Artikel-ID 785877, Seite 1-7
DOI: 10.3389/fgene.2022.785877
- Hübschmann, Daniel: Analysis of mutational signatures with yet another package for signature analysis / Daniel Hübschmann, Lea Jopp-Saile, Carolin Andresen, Stephen Krämer, Zuguang Gu, Christoph E. Heilig… , May 2021. - 18 S.
In: Genes, chromosomes & cancer, ISSN 1098-2264. 60(2021), 5, special issue vom: Mai, Seite 314-331
DOI: 10.1002/gcc.22918
- Meinhardt, Jenny: Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 / Jenny Meinhardt, Josefine Radke, Carsten Dittmayer, Jonas Franz, Carolina Thomas, Ronja Mothes, Mich… , 2021. - 8 S.
In: Nature neuroscience, ISSN 1546-1726. 24(2021), 2, Seite 168-175
DOI: 10.1038/s41593-020-00758-5
- Bieg, Matthias: Gene expression in solitary fibrous tumors (SFTs) correlates with anatomic localization and NAB2-STAT6 gene fusion variants / Matthias Bieg, Evgeny A. Moskalev, Rainer Will, Simone Hebele, Matthias Schwarzbach, Sanja Schmeck, … , 23 January 2021. - 16 S.
In: The American journal of pathology, ISSN 1525-2191. 191(2021), 4, Seite 602-617
DOI: 10.1016/j.ajpath.2020.12.015
- Derrien, Jennifer: The DNA methylation landscape of multiple myeloma shows extensive inter- and intrapatient heterogeneity that fuels transcriptomic variability / Jennifer Derrien, Catherine Guérin-Charbonnel, Victor Gaborit, Loïc Campion, Magali Devic, Elise Dou… , 09 August 2021. - 21 S.
In: Genome medicine, ISSN 1756-994X. 13(2021), Artikel-ID 127, Seite 1-21
DOI: 10.1186/s13073-021-00938-3
- Hübschmann, Daniel: Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas / Daniel Hübschmann et al., 5 May 2021. - 15 S.
In: Leukemia, ISSN 1476-5551. 35(2021), 7, Seite 2002-2016
DOI: 10.1038/s41375-021-01251-z
- Borchert, Florian: Knowledge bases and software support for variant interpretation in precision oncology / Florian Borchert, Andreas Mock, Aurelie Tomczak, Jonas Hügel, Samer Alkarkoukly, Alexander Knurr, An… , 10 May 2021. - 17 S.
In: Briefings in bioinformatics, ISSN 1477-4054. 22(2021), 6 vom: Nov., Artikel-ID bbab134, Seite 1-17
DOI: 10.1093/bib/bbab134
- Mayer, Gerhard: Implementing FAIR data management within the German Network for Bioinformatics Infrastructure (de.NBI) exemplified by selected use cases / Gerhard Mayer, Wolfgang Müller, Karin Schork, Julian Uszkoreit, Andreas Weidemann, Ulrike Wittig, Ma… , 16 February 2021. - 14 S.
In: Briefings in bioinformatics, ISSN 1477-4054. 22(2021), 5, Artikel-ID bbab010, Seite 1-14
DOI: 10.1093/bib/bbab010
- Krieger, Teresa G.: Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy / Teresa G. Krieger, Solange Le Blanc, Julia Jabs, Foo Wei Ten, Naveed Ishaque, Katharina Jechow, Oliv… , 05 October 2021. - 13 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 5826, Seite 1-13
DOI: 10.1038/s41467-021-26059-4
- Schmidt, Constanze: Prospective multicentric validation of a novel prediction model for paroxysmal atrial fibrillation / Constanze Schmidt, Sebastian Benda, Patricia Kraft, Felix Wiedmann, Sven Pleger, Antonius Büscher, D… , 2021. - 9 S.
In: Clinical research in cardiology, ISSN 1861-0692. 110(2021), 6, Seite 868-876
DOI: 10.1007/s00392-020-01773-z
- Gassen, Nils C.: SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antivirals / Nils C. Gassen, Jan Papies, Thomas Bajaj, Jackson Emanuel, Frederik Dethloff, Robert Lorenz Chua, Ja… , 21 June 2021. - 15 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 3818, Seite 1-15
DOI: 10.1038/s41467-021-24007-w
- Loske, Jennifer: Pre-activated antiviral innate immunity in the upper airways controls early SARS-CoV-2 infection in children / J. Loske, J. Röhmel, S. Lukassen, S. Stricker, V.G. Magalhães, J. Liebig, R.L. Chua, L. Thürmann, M.… , 18 August 2021. - 319-324$t6
In: Nature biotechnology, ISSN 1546-1696. 40(2021)
DOI: 10.1038/s41587-021-01037-9
- Park, Jeongbin: Author correction: Cell segmentation-free inference of cell types from in situ transcriptomics data / Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Ngu… , 28 June 2021. - 1 S.
In: Nature Communications, ISSN 2041-1723. 12(2021) vom: 28. Juni, Artikel-ID 4103, Seite 1
DOI: 10.1038/s41467-021-24405-0
- Park, Jeongbin: Cell segmentation-free inference of cell types from in situ transcriptomics data / Jeongbin Park, Wonyl Choi, Sebastian Tiesmeyer, Brian Long, Lars E. Borm, Emma Garren, Thuc Nghi Ngu… , 10 June 2021. - 13 S.
In: Nature Communications, ISSN 2041-1723. 12(2021) vom: 10. Juni, Artikel-ID 3545, Seite 1-13
DOI: 10.1038/s41467-021-23807-4
- Schwarz, Emanuel: Identifying multimodal signatures underlying the somatic comorbidity of psychosis : the COMMITMENT roadmap : guest editorial / Emanuel Schwarz, Dag Alnæs, Ole A. Andreassen, Han Cao, Junfang Chen, Franziska Degenhardt, Daria Do… , 2021. - 3 S.
In: Molecular psychiatry, ISSN 1476-5578. 26(2021), 3, Seite 722-724
DOI: 10.1038/s41380-020-00915-z
- Hoffmann, Mareike: Optogenetic control of Neisseria meningitidis Cas9 genome editing using an engineered, light-switchable anti-CRISPR protein / Mareike D Hoffmann, Jan Mathony, Julius Upmeier zu Belzen, Zander Harteveld, Sabine Aschenbrenner, C… , 2021. - 11 S.
In: Nucleic acids research, ISSN 1362-4962. 49(2021), 5, Seite e29-e29
DOI: 10.1093/nar/gkaa1198
- Wang, Qi: Integrative ranking of enhancer networks facilitates the discovery of epigenetic markers in cancer / Qi Wang, Yonghe Wu, Tim Vorberg, Roland Eils and Carl Herrmann, 31 May 2021. - 11 S.
In: Frontiers in genetics, ISSN 1664-8021. 12(2021) vom: 31. Mai, Artikel-ID 664654
DOI: 10.3389/fgene.2021.664654
- Tosti, Luca: Single-nucleus and in situ RNA-sequencing reveal cell topographies in the human pancreas / Luca Tosti, Yan Hang, Olivia Debnath, Sebastian Tiesmeyer, Timo Trefzer, Katja Steiger, Foo Wei Ten,… , 2021. - 26 S.
In: Gastroenterology, ISSN 1528-0012. 160(2021), 4, Seite 1330-1344.e11
DOI: 10.1053/j.gastro.2020.11.010
- Zowada, Martina: Functional states in tumor-initiating cell differentiation in human colorectal cancer / Martina K. Zowada, Stephan M. Tirier, Sebastian M. Dieter, Teresa G. Krieger, Ava Oberlack, Robert L… , 4 March 2021. - 32 S.
In: Cancers, ISSN 2072-6694. 13(2021), 5, Artikel-ID 1097, Seite 1-32
DOI: 10.3390/cancers13051097
- Lukassen, Sören: Conserved host-pathogen interactions identify novel treatment options in betacoronavirus infections / Soeren Lukassen and Roland Eils, 10 February 2021. - 3 S.
In: Signal transduction and targeted therapy, ISSN 2059-3635. 6(2021), Artikel-ID 57, Seite 1-3
DOI: 10.1038/s41392-021-00480-z
- Aslam, Muhammad: Putative second hit rare genetic variants in families with seemingly GBA-associated Parkinson’s disease / Muhammad Aslam, Nirosiya Kandasamy, Anwar Ullah, Nagarajan Paramasivam, Mehmet Ali Öztürk, Saima Nau… , 05 January 2021. - 10 S.
In: npj Genomic Medicine, ISSN 2056-7944. 6(2021,1) Artikel-Nummer 2, 10 Seiten
DOI: 10.1038/s41525-020-00163-8
- Trump, Saskia: Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19 / Saskia Trump, Soeren Lukassen, Markus S. Anker, Robert Lorenz Chua, Johannes Liebig, Loreen Thürmann… , 2021. - 12 S.
In: Nature biotechnology, ISSN 1546-1696. 39(2021), Seite 705-716
DOI: 10.1038/s41587-020-00796-1
- Espinet, Elisa: Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell-of-origin / Elisa Espinet, Zuguang Gu, Charles D. Imbusch, Nathalia A. Giese, Magdalena Buscher, Mariam Safavi, … , 2021. - 22 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 3, Seite 638-659
DOI: 10.1158/2159-8290.CD-20-1202
- Zapatka, Marc: The landscape of viral associations in human cancers / Marc Zapatka, Ivan Borozan, Daniel S. Brewer, Murat Iskar, Adam Grundhoff, Malik Alawi, Nikita Desai… , 05 February 2020. - 11 S. : Illustrationen, Diagramme
In: Nature genetics, ISSN 1546-1718. 52(2020), 3, Seite 320-330
DOI: 10.1038/s41588-019-0558-9
- Wu, Yonghe: Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype / Yonghe Wu, Michael Fletcher, Zuguang Gu, Qi Wang, Barbara Costa, Anna Bertoni, Ka-Hou Man, Magdalena… , 18 December 2020. - 19 S.
In: Nature Communications, ISSN 2041-1723. 11(2020), Artikel-ID 6434, Seite 1-19
DOI: 10.1038/s41467-020-20225-w
- Kaipa, Jagan Mohan: Transcriptome profiling reveals Silibinin dose-dependent response network in non-small lung cancer cells / Jagan Mohan Kaipa, Vytaute Starkuviene, Holger Erfle, Roland Eils, Evgeny Gladilin, 16 December 2020. - 26 S.
In: PeerJ, ISSN 2167-8359. 8(2020), 12, Artikel-ID e10373, Seite 1-26
DOI: 10.7717/peerj.10373
- Luiken, Sarah: NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis / Sarah Luiken, Angelika Fraas, Matthias Bieg, Raisatun Sugiyanto, Benjamin Goeppert, Stephan Singer, … , 13 February 2020. - 17 S.
In: Oncogene, ISSN 1476-5594. 39(2020), 15, Seite 3128-3144
DOI: 10.1038/s41388-020-1198-3
- Lukassen, Sören: Gene set inference from single-cell sequencing data using a hybrid of matrix factorization and variational autoencoders / Soeren Lukassen, Foo Wei Ten, Lukas Adam, Roland Eils and Christian Conrad, 07 December 2020. - 19 S.
In: Nature machine intelligence, ISSN 2522-5839. 2(2020), 12, Seite 800-819
DOI: 10.1038/s42256-020-00269-9
- Krieger, Teresa G.: Modeling glioblastoma invasion using human brain organoids and single-cell transcriptomics / Teresa G Krieger, Stephan M Tirier, Jeongbin Park, Katharina Jechow, Tanja Eisemann, Heike Peterziel… , 16 April 2020. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 8, Seite 1138-1149
DOI: 10.1093/neuonc/noaa091
- Whalley, Justin P.: Framework for quality assessment of whole genome cancer sequences / Justin P. Whalley, Ivo Buchhalter, Esther Rheinbay, Keiran M. Raine, Miranda D. Stobbe, Kortine Klei… , 07 October 2020
In: Nature Communications, ISSN 2041-1723. 11(2020) Artikel-Nummer 5040, 8 Seiten
DOI: 10.1038/s41467-020-18688-y
- Antwi, Enoch: Whole-genome fingerprint of the DNA methylome during chemically induced differentiation of the human AML cell line HL-60/S4 / Enoch B. Antwi, Ada Olins, Vladimir B. Teif, Matthias Bieg, Tobias Bauer, Zuguang Gu, Benedikt Brors… , 17 February 2020. - 11 S.
In: Biology open, ISSN 2046-6390. 9(2020), 3, Artikel-ID bio044222, Seite 1-11
DOI: 10.1242/bio.044222
- Feng, Bohai: Integrative analysis of ,multi-omics data identified EGFR and PTGS2 as key nodes in a gene regulatory network related to immune phenotypes in head and neck cancer / Bohai Feng, Ying Shen, Xavier Pastor Hostench, Matthias Bieg, Michaela Plath, Naveed Ishaque, Roland… , March 11, 2020. - 13 S.
In: Clinical cancer research, ISSN 1557-3265. 26(2020), 14, Seite 3616-3628
DOI: 10.1158/1078-0432.CCR-19-3997
- Eismann, Björn: Automated 3D light-sheet screening with high spatiotemporal resolution reveals mitotic phenotypes / Björn Eismann, Teresa G. Krieger, Jürgen Beneke, Ruben Bulkescher, Lukas Adam, Holger Erfle, Carl He… , 1 June 2020. - 11 S.
In: Journal of cell science, ISSN 1477-9137. 133(2020,11) Artikel-Nummer jcs245043, 11 Seiten
DOI: 10.1242/jcs.245043
- Chua, Robert Lorenz: COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis / Robert Lorenz Chua, Soeren Lukassen, Saskia Trump, Bianca P. Hennig, Daniel Wendisch, Fabian Pott, O… , 26 June 2020. - 10 S.
In: Nature biotechnology, ISSN 1546-1696. 38(2020), 8, Seite 970-979
DOI: 10.1038/s41587-020-0602-4
- Lukassen, Sören: SARS-CoV-2 receptor ACE2 and TMPRSS2 are primarily expressed in bronchial transient secretory cells / Soeren Lukassen, Robert Lorenz Chua, Timo Trefzer, Nicolas C Kahn, Marc A Schneider, Thomas Muley, H… , 14 April 2020
In: The EMBO journal, ISSN 1460-2075. 39(2020,10) Artikel-Nummer e105114, 39 Seiten
DOI: 10.15252/embj.20105114
- Sieverling, Lina Katharine: Genomic footprints of activated telomere maintenance mechanisms in cancer / Lina Sieverling, Chen Hong, Sandra D. Koser, Philip Ginsbach, Kortine Kleinheinz, Barbara Hutter, De… , 05 February 2020. - 13 S.
In: Nature Communications, ISSN 2041-1723. 11(2020) Artikel-Nummer 733, 13 Seiten
DOI: 10.1038/s41467-019-13824-9
- Aschenbrenner, Sabine: Coupling Cas9 to artificial inhibitory domains enhances CRISPR-Cas9 target specificity / Sabine Aschenbrenner, Stefan M. Kallenberger, Mareike D. Hoffmann, Adrian Huck, Roland Eils, Dominik… , 05 Feb 2020. - 12 S.
In: Science advances, ISSN 2375-2548. 6(2020,6) Artikel-Nummer eaay0187, Seite 1-12
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- "PRECiSe - Prätherapeutische epigenetische Stratifikation von CLL-Patienten" : Schlussbericht zum Teilprojekt B im e:Bio - Modul II - Verbundprojekt : Laufzeit des Vorhabens: 01.03.2016-28.02.2019 mit kostenneutraler Verlängerung bis zum 31.08.2019 / ausführende Stelle: Ruprecht-Karls-Universität Heidelberg ; Projektleiter: Prof. Dr. Roland Eils. -
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Heidelberg: Ruprecht-Karls-Universität Heidelberg, 29.01.2016. - 11 Blätter : Illustrationen, Diagramme
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- Wehler, Pierre: Optogenetic control of nuclear protein import in living cells using Light-Inducible Nuclear localization Signals (LINuS) / Pierre Wehler, Dominik Niopek, Roland Eils, and Barbara Di Ventura, 02 June 2016. - 15 S.
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- Suryawanshi, Vasantika: Between-species differences in gene copy number are enriched among functions critical for adaptive evolution in Arabidopsis halleri / Vasantika Suryawanshi, Ina N. Talke, Michael Weber, Roland Eils, Benedikt Brors, Stephan Clemens and… , 22 December 2016. - 22 S.
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- Koşaloğlu, Zeynep: Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases / Zeynep Koşaloğlu, Inka Zörnig, Niels Halama, Iris Kaiser, Ivo Buchhalter, Niels Grabe, Roland Eils, … , 04 Nov 2016. - 11 S.
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In: PeerJ, ISSN 2167-8359. 3(2016), Artikel-Nummer e1490, 20 Seiten
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- Waldhauer, Max: Backbone circularization of Bacillus subtilis family 11 xylanase increases its thermostability and its resistance against aggregation / Max C. Waldhauer, Silvan N. Schmitz, Constantin Ahlmann-Eltze, Jan G. Gleixner, Carolin C. Schmelas,… , 5 October 2015. - 13 S.
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DOI: 10.1038/nature08987
- Riehl, Astrid: Identification of the Rage-dependent gene regulatory network in a mouse model of skin inflammation / Astrid Riehl, Tobias Bauer, Benedikt Brors, Hauke Busch, Regina Mark, Julia Németh, Christoffer Gebh… , 05 October 2010. - 13 S.
In: BMC genomics, ISSN 1471-2164. 11(2010), Artikel-ID 537, Seite 1-13
DOI: 10.1186/1471-2164-11-537
- Neumann, Leo: Dynamics within the CD95 death-inducing signaling complex decide life and death of cells / Leo Neumann, Carina Pforr, Joel Beaudouin, Alexander Pappa, Nicolai Fricker, Peter H Krammer, Inna N… , 9 March 2010. - 17 S.
In: Molecular systems biology, ISSN 1744-4292. 6(2010), 1 vom: 1. Jan., Artikel-ID 352, Seite 1-17
DOI: 10.1038/msb.2010.6
- Kitiporn Plaimas: Identifying essential genes in bacterial metabolic networks with machine learning methods / Kitiporn Plaimas, Roland Eils, Rainer König, 03 May 2010. - 16 S.
In: BMC systems biology, ISSN 1752-0509. 4(2010), 1, Artikel-ID 56, Seite 1-16
DOI: 10.1186/1752-0509-4-56
- Gladilin, Evgeny: Contactless determination of nuclear compressibility using 3D image- and model-based analysis of drug-induced cellular deformation / E. Gladilin, M. Schulz, C. Kappel & R. Eils, 15 November 2010. - 11 S.
In: Journal of microscopy, ISSN 1365-2818. 240(2010), 3, Seite 216-226
DOI: 10.1111/j.1365-2818.2010.03394.x
- Bulashevska, Svetlana: Bayesian statistical modelling of human protein interaction network incorporating protein disorder information / Svetlana Bulashevska, Alla Bulashevska, Roland Eils, 25 January 2010. - 1-15$t15
In: BMC bioinformatics, ISSN 1471-2105. 11(2010), Artikel-ID 46
DOI: 10.1186/1471-2105-11-46
- Lewis, Nathan: Large-scale in silico modeling of metabolic interactions between cell types in the human brain / Nathan E. Lewis, Gunnar Schramm, Aarash Bordbar, Jan Schellenberger, Michael P. Andersen, Jeffrey K.… , 21 November 2010. - 7 S.
In: Nature biotechnology, ISSN 1546-1696. 28(2010), 12, Seite 1279-1285
DOI: 10.1038/nbt.1711
- Lewis, Nathan: Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models / Nathan E Lewis, Kim K Hixson, Tom M Conrad, Joshua A Lerman, Pep Charusanti, Ashoka D Polpitiya, Jos… , 27 July 2010. - 13 S.
In: Molecular systems biology, ISSN 1744-4292. 6(2010), 1 vom: Juli, Artikel-ID 390, Seite 1-13
DOI: 10.1038/msb.2010.47
- Baum, Patrick: Phenocopy : a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization / Patrick Baum, Ramona Schmid, Carina Ittrich, Werner Rust, Katrin Fundel-Clemens, Susanne Siewert, Ma… , December 10, 2010. - 15 S.
In: PLOS ONE, ISSN 1932-6203. 5(2010), 12, Artikel-ID e14272, Seite 1-15
DOI: 10.1371/journal.pone.0014272
- Löhr, J.-Matthias: Autoantibodies against the exocrine pancreas in autoimmune pancreatitis : gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process / J.-Matthias Löhr, Ralf Faissner, Dirk Koczan, Peter Bewerunge, Claudio Bassi, Benedikt Brors, Roland… , September 2010. - 12 S.
In: The American journal of gastroenterology, ISSN 1572-0241. 105(2010), 9, Seite 2060-2071
DOI: 10.1038/ajg.2010.141
- Löhr, J.-Matthias: Autoantibodies against the exocrine pancreas in autoimmune pancreatitis : gene and protein expression profiling and immunoassays identify pancreatic enzymes as a major target of the inflammatory process / J.-Matthias Löhr, Ralf Faissner, Dirk Koczan, Peter Bewerunge, Claudio Bassi, Benedikt Brors, Roland… , 2010
In: The American journal of gastroenterology, ISSN 0002-9270. 105(2010), 9, Seite 2060-2071
- Schramm, Gunnar: PathWave : discovering patterns of differentially regulated enzymes in metabolic pathways / Gunnar Schramm ; Stefan Wiesberg ; Nicolle Diessl ; Anna-Lena Kranz ; Vitalia Sagulenko ; Marcus Osw… . - 7 S.
In: Bioinformatics, ISSN 1367-4811. 26(2010), 9, S. 1225-1231
DOI: 10.1093/bioinformatics/btq113
- Schramm, Gunnar: Analyzing the regulation of metabolic pathways in human breast cancer / Gunnar Schramm; Eva-Maria Surmann; Stefan Wiesberg; Marcus Oswald; Gerhard Reinelt; Roland Eils; Rai… , 2010. - 10 S.
In: BMC medical genomics, ISSN 1755-8794. 3(2010) Artikel-Nr. 39, 10 S.
DOI: 10.1186/1755-8794-3-39
- Ivanchenko, Sergey: Dynamics of HIV-1 assembly and release / Sergey Ivanchenko, William J. Godinez, Marko Lampe, Hans-Georg Kräusslich, Roland Eils, Karl Rohr, C… , 2009. - 12 S.
In: PLoS pathogens, ISSN 1553-7374. 5(2009,11) Artikel-Nr. e1000652, 11 S.
DOI: 10.1371/journal.ppat.1000652
- Fatumo, Segun: Estimating novel potential drug targets of Plasmodium falciparum by analysing the metabolic network of knock-out strains in silico / Segun Fatumo ; Kitiporn Plaimas ; Jan-Philipp Mallm ; Gunnar Schramm ; Ezekiel Adebiyi ; Marcus Oswa… . - 8 S.
In: Infection, genetics and evolution, ISSN 1567-7257. 9(2009), 3, S. 351-358
DOI: 10.1016/j.meegid.2008.01.007
- Surmann, Eva Maria: Analyzing the regulation of metabolic pathways in human breast cancer / Eva Maria Surmann ; Gunnar Schramm ; Stefan Wiesberg ; Marcus Oswald ; Gerhard Reinelt ; Roland Eils… . - 8 S.
In: KDML 2009. (2009), S. 111-118
- Kitiporn Plaimas: Machine learning based analyses on metabolic networks supports high-throughput knockout screens / Kitiporn Plaimas, Jan-Phillip Mallm, Marcus Oswald, Fabian Svara, Victor Sourjik, Roland Eils and Ra…
In: BMC systems biology, ISSN 1752-0509. 2(2008) Artikel-Nr. 67, 11 Seiten
DOI: 10.1186/1752-0509-2-67
- Eils, Roland: "Ecolicence to Kill" erzielt die meisten Preise beim internationalen iGEM-Wettbewerb in Boston / Roland Eils ; Victor Sourjik. -
Heidelberg: Universität Heidelberg, 2008. - Online-Ressource
- Kitiporn Plaimas: Integrating genomic and transcriptomic data into graph based approaches for defining essential reactions in the metabolic network of Escherichia Coli / Kitiporn Plaimas, Marcus Oswald, Roland Eils and Rainer König. - 6 S.
In: LWA 2007. (2007), S. 55-60
- Wahler, Theodora: Group testing for pathway analysis improves comparability of different microarray datasets / Theodora Manoli, Norbert Gretz, Hermann-Josef Gröne, Marc Kenzelmann, Roland Eils and Benedikt Brors, [15 October 2006]. - 10$p2500-2506$t7 : Diagramme
In: Bioinformatics, ISSN 1367-4811. 22(2006), 20
DOI: 10.1093/bioinformatics/btl424
- Shahi, Priyanka: Argonaute - a database for gene regulation by mammalian microRNAs / Priyanka Shahi, Serguei Loukianiouk, Andreas Bohne-Lang, Marc Kenzelmann, Stefan Küffer, Sabine Maer… , 1 January 2006. - 4 S.
In: Nucleic acids research, ISSN 1362-4962. 34(2006), Suppl. 1$m1, Seite D115-D118
DOI: 10.1093/nar/gkj093
- Shahi, Priyanka: Argonaute : a database for gene regulation by mammalian microRNAs / Priyanka Shahi, Serguei Loukianiouk, Andreas Bohne-Lang, Marc Kenzelmann, Stefan Küffer, Sabine Maer… , 2006. - 4 S.
In: Nucleic acids research, ISSN 0305-1048. 34(2006), Suppl. 1, Seite D115-D118
- König, Rainer: Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms / Rainer König; Gunnar Schramm; Marcus Oswald; Hanna Seitz; Sebastian Sager; Marc Zapatka; Gerhard Rei… , 2006. - 14 S.
In: BMC bioinformatics, ISSN 1471-2105. 7(2006) Art.-Nr. 119, 14 S.
DOI: 10.1186/1471-2105-7-119
- Kriete, Andres: Computational systems biology / edited by Andres Kriete, Roland Eils. -
Amsterdam ; Boston: Elsevier, c2006. - Online Ressource (x, 409 p.) : ill. (some col.), ISBN 978-0-12-088786-6
- Bentele, Martin: Mathematical modeling reveals threshold mechanism in CD95-induced apoptosis / M. Bentele, I. Lavrik ... D. W. Heermann P.H. Krammer and R. Eils, 2004. - 13 S.
In: The journal of cell biology, ISSN 1540-8140. 166(2004), 6, Seite 839-851
DOI: 10.1083/jcb.200404158
- Münkel, Christian: Compartmentalization of interphase chromosomes observed in simulation and experiment / Christian Münkel, Roland Eils, Steffen Dietzel, Daniele Zink, Carsten Mehring, Gero Wedemann, Thomas… , 25 May 2002. - 13 S.
In: Journal of molecular biology, ISSN 1089-8638. 285(1999), 3, Seite 1053-1065
DOI: 10.1006/jmbi.1998.2361
- Eils, Roland: 3D reconstruction, mathematical modeling and simulation of chromatin structures in cell nuclei / vorgelegt von Roland Eils, 1995. - 184 S. : Ill., graph. Darst.
- Eils, Roland: Three-dimensional imaging approaches and Monte Carlo simulations : development of tools to study the morphology and distribution of chromosome territories and subchromosomal targets in human cell nuclei / Roland Eils, Kaan Saracoglu, Christian Münkel, Jorg Imhoff, Kurt Sätzler, Etienne Bertin, Steffen Di… , 1995. - 5 S.
In: Zoological studies, ISSN 1810-522X. 34(1995), Suppl. 1, Seite 7-11
- Eils, Roland: Application of confocal laser microscopy and three-dimensional Voronoi diagrams for volume and surface estimates of interphase chromosomes / R. Eils, E. Bertin, K. Saracoglu, B. Rinke, E. Schröck, F. Parazza, Y. Usson, M. Robert-Nicoud, E.H.… , February 1995. - 12 S.
In: Journal of microscopy, ISSN 1365-2818. 177(1995), 2, Seite 150-161
DOI: 10.1111/j.1365-2818.1995.tb03545.x
