
Pfister, Stefan Prof. Dr. med.Universität HeidelbergHeidelberg
Refine publication list
Year of publication
Type of Publication
Language
Co-author (Univ. of Heidelberg)
- Sturm, Dominik (71)
- Lichter, Peter (71)
- Schrimpf, Daniel (65)
- Pajtler, Kristian Wilfried (60)
- Capper, David (60)
- Witt, Hendrik (58)
- Herold-Mende, Christel (56)
- Wick, Wolfgang (52)
- Stichel, Damian (49)
- Reuss, David (49)
- Sill, Martin (45)
- Kölsche, Christian (41)
- Kulozik, Andreas (40)
- Sievers, Philipp (38)
- Remke, Marc (34)
- Unterberg, Andreas (33)
- Jäger, Natalie (32)
- Pfaff, Elke (26)
- Reinhardt, Annekathrin (26)
- Tilburg, Cornelis M. van (26)
- Selt, Florian (24)
- Hielscher, Thomas (24)
- Eils, Roland (23)
- Ecker, Jonas (23)
- Johann, Pascal-David (22)
- Wefers, Annika K. (22)
- Platten, Michael (21)
- Jones, Barbara Christine (19)
- Brors, Benedikt (18)
- Zapatka, Marc (18)
- Hovestadt, Volker (16)
- Bender, Sebastian (15)
- Chavez, Lukas (15)
- (further entries exist...)
Co-author (external)
- Schüller, Ulrich (7)
- Giangaspero, Felice (7)
- Schüller, Ulrich (7)
- Northcott, Paul A. (7)
- Hawkins, Cynthia (6)
- Joshi, Piyush (6)
- Mawrin, Christian (6)
- Zheludkova, Olga (6)
- Reifenberger, Guido (6)
- Clifford, Steven C. (6)
- Molenaar, Jan J. (6)
- Koster, Jan (5)
- Taylor, Michael D. (5)
- Reifenberger, Guido (5)
- Bueren, André von (5)
- Albrecht, Steffen (5)
- Kratz, Christian Peter (5)
- Ramaswamy, Vijay (5)
- Figarella-Branger, Dominique (5)
- Eberhart, Charles G. (5)
- Tippelt, Stephan (5)
- Tabori, Uri (5)
- Timmermann, Beate (5)
- Rutka, James T. (5)
- Gajjar, Amar (4)
- Karajannis, Matthias A. (4)
- Wu, Xiaochong (4)
- Hübner, Jens-Martin (4)
- Varlet, Pascale (4)
- Hasselblatt, Martin (4)
- Perry, Arie (4)
- Haberler, Christine (4)
- Gajjar, Amar (4)
- (further entries exist...)
Publications in heiBIB 
- Lämmerer, Anna: Alternative lengthening of telomere-based immortalization renders H3G34R-mutant diffuse hemispheric glioma hypersensitive to PARP inhibitor combination regimens / Anna Laemmerer, Christian Lehmann, Lisa Mayr, Katharina Bruckner, Lisa Gabler, Daniel Senfter, Phili… , March 2025. - 17 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 27(2025), 3 vom: März, Seite 811-827
DOI: 10.1093/neuonc/noae228
- Obrecht-Sturm, Denise: Distinct relapse pattern across molecular ependymoma types / Denise Obrecht-Sturm, Melanie Schoof, Alicia Eckhardt, Martin Mynarek, Mark R Gilbert, Kenneth Aldap… , 22 August 2024. - 10 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 27(2025), 1 vom: Jan., Seite 267-276
DOI: 10.1093/neuonc/noae166
- Filippidou, Maria: Soft tissue undifferentiated sarcoma carrying a novel Onecut1::Nutm1 fusion : letter to the editor / Maria Filippidou, Stavros Glentis, Efthymia Rigatou, Philipp Sievers, Florian Selt, Efthymios Dimitr… , January 2025. - 4 S. : Illustrationen
In: Pediatric blood & cancer, ISSN 1545-5017. 72(2025), 1 vom: Jan., Artikel-ID e31427, Seite 1-4
DOI: 10.1002/pbc.31427
- Okonechnikov, Konstantin: Oncogene aberrations drive medulloblastoma progression, not initiation / Konstantin Okonechnikov, Piyush Joshi, Verena Körber, Anne Rademacher, Michele Bortolomeazzi, Jan-Ph… , 07 May 2025. - 34 S.
In: Nature, ISSN 1476-4687. (2025), Seite 1-11, [1-13]
DOI: 10.1038/s41586-025-08973-5
- Schwalbe, Edward C.: Molecular and clinical heterogeneity within MYC-family amplified medulloblastoma is associated with survival outcomes : a multicenter cohort study / Edward C. Schwalbe, Janet C. Lindsey, Marina Danilenko, Rebecca M. Hill, Stephen Crosier, Sarra L. R… , January 2025. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 27(2025), 1, Seite 222-236
DOI: 10.1093/neuonc/noae178
- Perrino, Melissa: Update on pediatric cancer surveillance recommendations for patients with Neurofibromatosis type 1, Noonan syndrome, CBL syndrome, Costello syndrome, and related RASopathies / Melissa R. Perrino, Anirban Das, Sarah R. Scollon, Sarah G. Mitchell, Mary-Louise C. Greer, Marielle… , 1 November 2024. - 10 S.
In: Clinical cancer research, ISSN 1557-3265. 30(2024), 21 vom: Nov., Seite 4834-4843
DOI: 10.1158/1078-0432.CCR-24-1611
- Hansford, Jordan R.: Comments and controversies in oncology : the tribulations of trials developing ONC201 / Jordan R. Hansford, MBBS, MSc, Gauthier Bouche, MD, Vijay Ramaswamy, MD, PhD, Nada Jabado, MD, PhD, … , December 2024. - 5 S.
In: Journal of clinical oncology, ISSN 1527-7755. 42(2024), 35 vom: Dez., Seite 4126-4129
DOI: 10.1200/JCO.24.00709
- Tauziède-Espariat, Arnault: Diffuse pediatric high-grade glioma of methylation-based RTK2A and RTK2B subclasses present distinct radiological and histomolecular features including Gliomatosis cerebri phenotype / Arnault Tauziède-Espariat, Lea L. Friker, Gunther Nussbaumer, Brigitte Bison, Volodia Dangouloff-Ros… , 18 November 2024. - 11 S. : Illustrationen
In: Acta Neuropathologica Communications, ISSN 2051-5960. 12(2024), 1, Seite 1-11
DOI: 10.1186/s40478-024-01881-1
- Shiraishi, Ryo: Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression / Ryo Shiraishi, Gabriele Cancila, Kohei Kumegawa, Jacob Torrejon, Irene Basili, Flavia Bernardi, Patr… , 9 September 2024. - 30 S. : Illustrationen
In: Developmental cell, ISSN 1878-1551. 59(2024), 17, Seite 2302-2319, e1-12
DOI: 10.1016/j.devcel.2024.05.013
- Sievers, Philipp: Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations / Philipp Sievers, Franck Bielle, Kirsten Göbel, Daniel Schrimpf, Lucia Nichelli, Bertrand Mathon, Rom… , 18 July 2024. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 148(2024), 1, Artikel-ID 7, Seite 1-5
DOI: 10.1007/s00401-024-02766-2
- Godbole, Shweta: Multiomic profiling of medulloblastoma reveals subtype-specific targetable alterations at the proteome and N-glycan level / Shweta Godbole, Hannah Voß, Antonia Gocke, Simon Schlumbohm, Yannis Schumann, Bojia Peng, Martin Myn… , 24 July 2024. - 24 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 6237, Seite 1-24
DOI: 10.1038/s41467-024-50554-z
- Kocher, Daniela: Rebound growth of BRAF mutant pediatric glioma cells after MAPKi withdrawal is associated with MAPK reactivation and secretion of microglia-recruiting cytokines / Daniela Kocher, Lei Cao, Romain Guiho, Melanie Langhammer, Yun-Lu Lai, Pauline Becker, Hiba Hamdi, D… , 17 April 2024. - 16 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 168(2024), 2 vom: Juni, Seite 317-332
DOI: 10.1007/s11060-024-04672-9
- Mynarek, Martin: Risk factors for domain-specific neurocognitive outcome in pediatric survivors of a brain tumor in the posterior fossa : results of the HIT 2000 trial / Martin Mynarek, Anne Rossius, Anika Guiard, Holger Ottensmeier, Katja von Hoff, Denise Obrecht-Sturm… , November 2024. - 12 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 26(2024), 11 vom: Nov., Seite 2113-2124
DOI: 10.1093/neuonc/noae092
- Obrecht-Sturm, Denise: Pineal anlage tumor : clinical and diagnostic features, and rationales for treatment / Denise Obrecht-Sturm, Elke Pfaff, Martin Mynarek, Brigitte Bison, Martina Rodehüser, Martina Becker,… , 22 January 2024. - 10 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 166(2024), 2 vom: Jan., Seite 359-368
DOI: 10.1007/s11060-023-04547-5
- Hansford, Jordan R.: Update on cancer predisposition syndromes and surveillance guidelines for childhood brain tumors / Jordan R. Hansford, Anirban Das, Rose B. McGee, Yoshiko Nakano, Jack Brzezinski, Sarah R. Scollon, S… , April 4, 2024. - 8 S.
In: Clinical cancer research, ISSN 1557-3265. 30(2024), 11 vom: Juni, Seite 2342-2350
DOI: 10.1158/1078-0432.CCR-23-4033
- Adolph, Jonas E.: Radiotherapy for recurrent medulloblastoma in children and adolescents : survival after re-irradiation and first-time irradiation / Jonas E. Adolph, Gudrun Fleischhack, Sebastian Tschirner, Lydia Rink, Christine Dittes, Ruth Mikasch… , 22 May 2024. - 13 S. : Illustrationen
In: Cancers, ISSN 2072-6694. 16(2024), 11, Artikel-ID 1955, Seite 1-13
DOI: 10.3390/cancers16111955
- Okonechnikov, Konstantin: Clinically unfavorable transcriptome subtypes of non-WNT/non-SHH medulloblastomas are associated with a predominance in proliferating and progenitor-like cell subpopulations / Konstantin Okonechnikov, Daniel Schrimpf, Jan Koster, Philipp Sievers, Till Milde, Felix Sahm, David… , 07 June 2024. - 11 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 147(2024), Artikel-ID 95, Seite 1-11
DOI: 10.1007/s00401-024-02746-6
- Zuckermann, Marc: Capmatinib is an effective treatment for MET-fusion driven pediatric high-grade glioma and synergizes with radiotherapy / Marc Zuckermann, Chen He, Jared Andrews, Aditi Bagchi, Roketa Sloan-Henry, Brandon Bianski, Jia Xie,… , 07 June 2024. - 19 S. : Illustrationen
In: Molecular cancer, ISSN 1476-4598. 23(2024), Artikel-ID 123, Seite 1-19
DOI: 10.1186/s12943-024-02027-6
- Gilbertson, Richard J.: The virtual child / Richard J. Gilbertson, Sam Behjati, Anna-Lisa Böttcher, Marianne E. Bronner, Matthew Burridge, Henri… , April 04 2024. - 5 S. : Illustrationen
In: Cancer discovery, ISSN 2159-8290. 14(2024), 4 vom: Apr., Seite 663-668
DOI: 10.1158/2159-8290.CD-23-1500
- Ahmad, Olfat: IDH mutation, glioma immunogenicity, and therapeutic challenge of primary mismatch repair deficient IDH-mutant astrocytoma PMMRDIA : a systematic review / Olfat Ahmad, Tahani Ahmad and Stefan M. Pfister, 09 February 2024. - 20 S. : Illustrationen
In: Molecular oncology, ISSN 1878-0261. (2024), Seite 1-20
DOI: 10.1002/1878-0261.13598
- Ghasemi, David R.: Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage / David R. Ghasemi, Konstantin Okonechnikov, Anne Rademacher, Stephan Tirier, Kendra K. Maass, Hanna S… , 08 January 2024. - 20 S.
In: Nature Communications, ISSN 2041-1723. 15(2024), Artikel-ID 269, Seite 1-20
DOI: 10.1038/s41467-023-44117-x
- Sepp, Mari: Cellular development and evolution of the mammalian cerebellum / Mari Sepp, Kevin Leiss, Florent Murat, Konstantin Okonechnikov, Piyush Joshi, Evgeny Leushkin, Lisa … , 2024. - 9 S.
In: Nature, ISSN 1476-4687. 625(2024), 7996, Seite 788-796
DOI: 10.1038/s41586-023-06884-x
- Projektgruppe EURAT: Stellungnahme zur Rückmeldung genetischer Zusatzbefunde Minderjähriger : Heidelberg, Oktober 2023 / Projektgruppe EURAT, Ethische und Rechtliche Aspekte der Translationalen Medizin ; mitwirkende Autor… . -
Heidelberg: Sektion für Translationale Medizinethik, [2023]. - 130 Seiten
- Heipertz, Anna-Elisa: Outcome of children and adolescents with relapsed/refractory/progressive malignancies treated with molecularly informed targeted drugs in the pediatric precision oncology registry INFORM / Anna-Elisa Heipertz, MD, Kristian W. Pajtler, MD, Elke Pfaff, MD, Kathrin Schramm, Dr. rer. nat., Mi… , June 26, 2023. - 12 S. : Illustrationen
In: JCO precision oncology, ISSN 2473-4284. (2023), 7, Artikel-ID e2300015, Seite 1-12
DOI: 10.1200/PO.23.00015
- Kolodziejczak, Anna: Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome / Anna S Kolodziejczak, Lea Guerrini-Rousseau, Julien Masliah Planchon, Jonas Ecker, Florian Selt, Mar… , December 2023. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 12 vom: Dez., Seite 2273-2286
DOI: 10.1093/neuonc/noad114
- White, Christine: Implementation of DNA methylation array profiling in pediatric central nervous system tumors : the AIM BRAIN project : an Australian and New Zealand children's haematology/oncology group study / Christine L. White, Kathryn M. Kinross, Molly K. Moore, Elnaz Rasouli, Robyn Strong, Janelle M. Jone… , October 2023. - 20 S. : Illustrationen
In: The journal of molecular diagnostics, ISSN 1943-7811. 25(2023), 10 vom: Okt., Seite 709-728
DOI: 10.1016/j.jmoldx.2023.06.013
- Selt, Florian: Generation of patient-derived pediatric pilocytic astrocytoma in-vitro models using SV40 large T : evaluation of a modeling workflow / Florian Selt, Ahmed El Damaty, Martin U. Schuhmann, Romain Sigaud, Jonas Ecker, Philipp Sievers, Dan… , 24 November 2023. - 12 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 165(2023), 3 vom: Nov., Seite 467-478
DOI: 10.1007/s11060-023-04500-6
- Mynarek, Martin: Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts / Martin Mynarek, Denise Obrecht, Martin Sill, Dominik Sturm, Katja Kloth-Stachnau, Florian Selt, Jona… , 2 December 2022. - 16 S. : Illustrationen, Diagramme
In: Acta neuropathologica, ISSN 1432-0533. 145(2023), 1, Seite 97-112
DOI: 10.1007/s00401-022-02522-4
- Sigaud, Romain: MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas / Romain Sigaud, Thomas K. Albert, Caroline Hess, Thomas Hielscher, Nadine Winkler, Daniela Kocher, Ca… , 27 July 2023. - 21 S.
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 4533, Seite 1-21
DOI: 10.1038/s41467-023-40235-8
- Okonechnikov, Konstantin: 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma / Konstantin Okonechnikov, Aylin Camgöz, Owen Chapman, Sameena Wani, Donglim Esther Park, Jens-Martin … , 21 April 2023. - 16 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 2300, Seite 1-16
DOI: 10.1038/s41467-023-38044-0
- Keck, Michaela-Kristina: Correction to: Amplification of the PLAG-family genes - PLAGL1 and PLAGL2 - is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification / Michaela-Kristina Keck, Martin Sill, Andrea Wittmann, Piyush Joshi, Damian Stichel, Pengbo Beck, Kon… , April 2023. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 145(2023), 4, Seite 511-514
DOI: 10.1007/s00401-023-02538-4
- Rahmanzade, Ramin: Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics / Ramin Rahmanzade, Elke Pfaff, Rouzbeh Banan, Philipp Sievers, Abigail K. Suwala, Felix Hinz, Henri B… , 30 September 2023. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 146(2023), 6, Seite 853-856
DOI: 10.1007/s00401-023-02638-1
- Tauziède-Espariat, Arnault: Pediatric meningiomas : a literature review and diagnostic update / Arnault Tauziède-Espariat, Stefan M. Pfister, Christian Mawrin, and Felix Sahm, May 2023. - 7 S.
In: Neuro-oncology advances, ISSN 2632-2498. 5(2023), S1$m5, Seite i105-i111
DOI: 10.1093/noajnl/vdac165
- Okonechnikov, Konstantin: Mapping pediatric brain tumors to their origins in the developing cerebellum / Konstantin Okonechnikov, Piyush Joshi, Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, M… , October 2023. - 15 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 25(2023), 10 vom: Okt., Seite 1895-1909
DOI: 10.1093/neuonc/noad124
- Forum Marsilius-Kolleg
Bd. 23. - Jungkunz, Martin: Position paper on the return of additional genetic findings in minors / Martin Jungkunz, Kai Cornelius, Christoph Schickhardt, Nicola Dikow, Eva Winkler, Benedikt Brors, St… . -
Heidelberg: Marsilius-Kolleg, 2023-10-30. - 1 Online-Ressource (120 Seiten)
- Forum Marsilius-Kolleg
Bd. 23. - Projektgruppe EURAT: Stellungnahme zur Rückmeldung genetischer Zusatzbefunde Minderjähriger / Martin Jungkunz, Kai Cornelius, Christoph Schickhardt, Nicola Dikow, Eva Winkler, Benedikt Brors, St… . -
Heidelberg: Marsilius-Kolleg, 2023-10-30. - 1 Online-Ressource (130 Seiten)
DOI: 10.11588/fmk.2023.23.98739
- Nabbi, Arash: Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours / Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S.Y. … , 2023. - 24 S.
In: Genome medicine, ISSN 1756-994X. 15(2023), Artikel-ID 67, Seite 1-24
DOI: 10.1186/s13073-023-01219-x
- Moreno, Lucas: Combination early-phase trials of anticancer agents in children and adolescents / Lucas Moreno, Steven G. DuBois, Julia Glade Bender, Audrey Mauguen, Nick Bird, Vickie Buenger, Miche… , June 20, 2023. - 16 S.
In: Journal of clinical oncology, ISSN 1527-7755. 41(2023), 18 vom: Juni, Seite 3408-3422
DOI: 10.1200/JCO.22.02430
- Luo, Zaili: Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability / Zaili Luo, Dazhuan Xin, Yunfei Liao, Kalen Berry, Sean Ogurek, Feng Zhang, Liguo Zhang, Chuntao Zhao… , 10 February 2023. - 19 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 14(2023), Artikel-ID 762, Seite 1-19
DOI: 10.1038/s41467-023-36400-8
- Ahmad, Olfat: BRCA1/2 potential founder variants in the Jordanian population : an opportunity for a customized screening panel / Olfat Ahmad, Christian Sutter, Steffen Hirsch, Stefan M. Pfister and Christian P. Schaaf, 2023. - 9 S. : Illustrationen
In: Hereditary cancer in clinical practice, ISSN 1897-4287. 21(2023), Artikel-ID 11, Seite 1-9
DOI: 10.1186/s13053-023-00256-2
- Funke, Viktoria: Group-specific cellular metabolism in Medulloblastoma / Viktoria L.E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, … , 05 June 2023. - 16 S. : Illustrationen
In: Journal of translational medicine, ISSN 1479-5876. 21(2023), Artikel-ID 363, Seite 1-16
DOI: 10.1186/s12967-023-04211-6
- Sievers, Philipp: Pediatric-type high-grade neuroepithelial tumors with CIC gene fusion share a common DNA methylation signature / Philipp Sievers, Martin Sill, Daniel Schrimpf, Zied Abdullaev, Andrew M. Donson, Jessica A. Lake, De… , 2023. - 8 S. : Illustrationen
In: npj precision oncology, ISSN 2397-768X. 7(2023), Artikel-ID 30, Seite 1-8
DOI: 10.1038/s41698-023-00372-1
- Ecker, Jonas: Corrigendum to ‘Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry’ [Eur J Cancer 180 (2023) 71-84] / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , May 2023. - 2 S.
In: European journal of cancer, ISSN 1879-0852. 184(2023) vom: Mai, Seite 200-201
DOI: 10.1016/j.ejca.2023.02.024
- Keck, Michaela-Kristina: Amplification of the PLAG-family genes - PLAGL1 and PLAGL2 - is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification / Michaela-Kristina Keck, Martin Sill, Andrea Wittmann, Piyush Joshi, Damian Stichel, Pengbo Beck, Kon… , January 2023. - 21 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 145(2023), 1, Seite 49-69
DOI: 10.1007/s00401-022-02516-2
- Morfouace, Marie: Comprehensive molecular profiling of sarcomas in adolescent and young adult patients : results of the EORTC SPECTA-AYA international proof-of-concept study / Marie Morfouace, Peter Horak, Simon Kreutzfeldt, Aleksandra Stevovic, Teresa de Rojas, Evgeniya Deni… , 2023. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 178(2023), Seite 216-226
DOI: 10.1016/j.ejca.2022.10.020
- Ulrich, Elias: Revana : a comprehensive tool for regulatory variant analysis and visualization of cancer genomes / Elias Ulrich, Stefan M. Pfister and Natalie Jäger, January 2023. - 3 S.
In: Bioinformatics, ISSN 1367-4811. 39(2023), 1, Artikel-ID btac831, Seite 1-3
DOI: 10.1093/bioinformatics/btac831
- Pun, Matthew: Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways / Matthew Pun, Drew Pratt, Patricia R. Nano, Piyush K. Joshi, Li Jiang, Bernhard Englinger, Arvind Rao… , 09 February 2023. - 19 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 11(2023), Artikel-ID 25, Seite 1-19
DOI: 10.1186/s40478-023-01514-z
- Thatikonda, Venu: Comprehensive analysis of mutational signatures reveals distinct patterns and molecular processes across 27 pediatric cancers / Venu Thatikonda, S.M. Ashiqul Islam, Robert J. Autry, Barbara C. Jones, Susanne N. Gröbner, Gregor W… , 26 January 2023. - 28 S.
In: Nature cancer, ISSN 2662-1347. 4(2023), 2 vom: Jan., Seite 276-289
DOI: 10.1038/s43018-022-00509-4
- Ecker, Jonas: Molecular diagnostics enables detection of actionable targets : the Pediatric Targeted Therapy 2.0 registry / Jonas Ecker, Florian Selt, Dominik Sturm, Martin Sill, Andrey Korshunov, Steffen Hirsch, David Cappe… , February 2023. - 14 S. : Illustrationen
In: European journal of cancer, ISSN 1879-0852. 180(2023) vom: Feb., Seite 71-84
DOI: 10.1016/j.ejca.2022.11.015
- Sturm, Dominik: Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology / Dominik Sturm, David Capper, Felipe Andreiuolo, Marco Gessi, Christian Kölsche, Annekathrin Reinhard… , 16 March 2023. - 10 S.
In: Nature medicine, ISSN 1546-170X. 29(2023), 4, Seite 917-926
DOI: 10.1038/s41591-023-02255-1
- Patel, Areeba: Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study : correspondence / Areeba Patel, Helin Dogan, Alexander Payne, Elena Krause, Philipp Sievers, Natalie Schoebe, Daniel S… , 31 March 2022. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 143(2022), 5, Seite 609-612
DOI: 10.1007/s00401-022-02415-6
- Orth, Martin Franz: Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation / Martin F. Orth, Didier Surdez, Tobias Faehling, Anna C. Ehlers, Aruna Marchetto, Sandrine Grossetête… , December 6, 2022. - 28 S. : Illustrationen, Diagramme
In: Cell reports, ISSN 2211-1247. 41(2022), 10, Artikel-ID 111761, Seite 1-28
DOI: 10.1016/j.celrep.2022.111761
- Reinhardt, Annekathrin: Anaplastic ganglioglioma : a diagnosis comprising several distinct tumour types : original article / Annekathrin Reinhardt, Kristin Pfister, Daniel Schrimpf, Damian Stichel, Felix Sahm, David E. Reuss,… , December 2022. - 14 S.
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 48(2022), 7 vom: Dez., Artikel-ID e12847, Seite 1-14
DOI: 10.1111/nan.12847
- Bartl, Jasmin: The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors / Jasmin Bartl, Marco Zanini, Flavia Bernardi, Antoine Forget, Lena Blümel, Julie Talbot, Daniel Picar… , 13 July 2022. - 15 S.
In: Nature Communications, ISSN 2041-1723. 13(2022) vom: Juli, Artikel-ID 4061, Seite 1-15
DOI: 10.1038/s41467-022-31574-z
- Jurmeister, Philipp: DNA methylation-based classification of sinonasal tumors / Philipp Jurmeister, Stefanie Glöß, Renée Roller, Maximilian Leitheiser, Simone Schmid, Liliana H. Mo… , 28 November 2022. - 14 S.
In: Nature Communications, ISSN 2041-1723. 13(2022), Artikel-ID 7148, Seite 1-14
DOI: 10.1038/s41467-022-34815-3
- Langenberg, Karin: Implementation of paediatric precision oncology into clinical practice : the individualized therapies for children with cancer program ‘iTHER’ / Karin P.S. Langenberg, Michael T. Meister, Jette J. Bakhuizen, Judith M. Boer, Natasha K.A. van Eijk… , 29 September 2022. - 15 S.
In: European journal of cancer, ISSN 1879-0852. 175(2022), Seite 311-325
DOI: 10.1016/j.ejca.2022.09.001
- Richardson, Stacey: Emergence and maintenance of actionable genetic drivers at medulloblastoma relapse / Stacey Richardson, Rebecca M. Hill, Christopher Kui, Janet C Lindsey, Yura Grabovksa, Claire Keeling… , January 2022. - 13 S.
In: Neuro-Oncology, ISSN 1523-5866. 24(2022), 1, Seite 153-165
DOI: 10.1093/neuonc/noab178
- Juhnke, Björn-Ole: Treatment of embryonal tumors with multilayered rosettes with carboplatin/etoposide induction and highdose chemotherapy within the prospective P-HIT trial / B.-Ole Juhnke, Marco Gessi, Nicolas U. Gerber, Carsten Friedrich, Martin Mynarek, André O. von Buere… , January 2022. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 24(2022), 1, Seite 127-137
DOI: 10.1093/neuonc/noab100
- Peterziel, Heike: Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM / Heike Peterziel, Nora Jamaladdin, Dina ElHarouni, Xenia F. Gerloff, Sonja Herter, Petra Fiesel, Yann… , 27 December 2022. - 17 S.
In: npj precision oncology, ISSN 2397-768X. 6(2022), Artikel-ID 94, Seite 1-17
DOI: 10.1038/s41698-022-00335-y
- Penkert, Judith Rebekka: Genotype-phenotype associations within the Li-Fraumeni spectrum : a report from the German registry / Judith Penkert, Farina J. Strüwe, Christina M. Dutzmann, Beate B. Doergeloh, Emilie Montellier, Clai… , 2022. - 5 S.
In: Journal of hematology & oncology, ISSN 1756-8722. 15(2022), Artikel-ID 107, Seite 1-5
DOI: 10.1186/s13045-022-01332-1
- Tsai, Jessica W.: FOXR2 Is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits / Jessica W. Tsai, Paloma Cejas, Dayle K. Wang, Smruti Patel, David W. Wu, Phonepasong Arounleut, Xin … , September 02 2022. - 22 S.
In: Cancer research, ISSN 1538-7445. 82(2022), 17, Seite 2980-3001
DOI: 10.1158/0008-5472.CAN-22-0671
- Blümel, Lena: Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors / Lena Blümel, Nan Qin, Johannes Berlandi, Eunice Paisana, Rita Cascão, Carlos Custódia, David Pauck, … , 20 September 2022. - 13 S.
In: Cell death & disease, ISSN 2041-4889. 13(2022), 9, Artikel-ID 806, Seite 1-13
DOI: 10.1038/s41419-022-05243-4
- Hasselblatt, Martin: SMARCB1-deficient and SMARCA4-deficient malignant brain tumors with complex copy number alterations and TP53 mutations may represent the first clinical manifestation of Li-Fraumeni syndrome / Martin Hasselblatt, MD, Christian Thomas, MD, Aniello Federico, PhD, Karolina Nemes, MD, Pascal D. J… , 2022. - 7 S.
In: The American journal of surgical pathology, ISSN 1532-0979. 46(2022), 9, Seite 1277-1283
DOI: 10.1097/PAS.0000000000001905
- Hill, Rebecca M.: Relapsed medulloblastoma in pre-irradiated patients : current practice for diagnostics and treatment / Rebecca M. Hill, Sabine L.A. Plasschaert, Beate Timmermann, Christelle Dufour, Kristian Aquilina, Sh… , 2022. - 34 S.
In: Cancers, ISSN 2072-6694. 14(2022), 1, Artikel-ID 126, Seite 1-34
DOI: 10.3390/cancers14010126
- Schubert, Nil A.: Target actionability review to evaluate CDK4/6 as a therapeutic target in paediatric solid and brain tumours / Nil A. Schubert, Celine Y. Chen, Ana Rodríguez, Jan Koster, Michele Dowless, Stefan M. Pfister, Davi… , 4 June 2022. - 13 S.
In: European journal of cancer, ISSN 1879-0852. 170(2022), Seite 196-208
DOI: 10.1016/j.ejca.2022.04.028
- Delaidelli, Alberto: Clinically tractable outcome prediction of non-WNT/non-SHH medulloblastoma based on TPD52 IHC in a multicohort study / Alberto Delaidelli, Christopher Dunham, Mariarita Santi, Gian Luca Negri, Joanna Triscott, Olga Zhel… , January 05 2022. - 13 S.
In: Clinical cancer research, ISSN 1557-3265. 28(2022), 1, Seite 116-128
DOI: 10.1158/1078-0432.CCR-21-2057
- Ebrahimi, Azadeh: Pleomorphic xanthoastrocytoma is a heterogeneous entity with pTERT mutations prognosticating shorter survival / Azadeh Ebrahimi, Andrey Korshunov, Guido Reifenberger, David Capper, Joerg Felsberg, Elena Trisolini… , Jan 10 2022. - 10 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 10(2022), Artikel-ID 5, Seite 1-10
DOI: 10.1186/s40478-021-01308-1
- Catanzaro, Giuseppina: MiR-1248 : a new prognostic biomarker able to identify supratentorial hemispheric pediatric low-grade gliomas patients associated with progression / Giuseppina Catanzaro, Zein Mersini Besharat, Andrea Carai, Natalie Jäger, Elena Splendiani, Carole C… , 17 June 2022. - 17 S.
In: Biomarker Research, ISSN 2050-7771. 10(2022), Artikel-ID 44, Seite 1-17
DOI: 10.1186/s40364-022-00389-x
- Fresnais, Margaux: Analytical performance evaluation of new DESI enhancements for targeted drug quantification in tissue sections / Margaux Fresnais, Siwen Liang, Marius Breitkopf, Joshua Raoul Lindner, Emmanuelle Claude, Steven Pri… , 1 June 2022. - 18 S.
In: Pharmaceuticals, ISSN 1424-8247. 15(2022), 6, special issue, Artikel-ID 694, Seite 1-18
DOI: 10.3390/ph15060694
- Keller, Kaylee M.: Target actionability review : a systematic evaluation of replication stress as a therapeutic target for paediatric solid malignancies / Kaylee M. Keller, Sonja Krausert, Apurva Gopisetty, Dan Luedtke, Jan Koster, Nil A. Schubert, Ana Ro… , 2022. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 162(2022) vom: Feb., Seite 107-117
DOI: 10.1016/j.ejca.2021.11.030
- Beck, Pengbo: The genomic landscape of pediatric renal cell carcinomas / Pengbo Beck, Barbara Selle, Lukas Madenach, David T.W. Jones, Christian Vokuhl, Apurva Gopisetty, Ar… , April 15, 2022. - 24 S.
In: iScience, ISSN 2589-0042. 25(2022), 4 vom: 15. Apr., Artikel-ID 104167, Seite 1-24
DOI: 10.1016/j.isci.2022.104167
- Fresnais, Margaux: Important requirements for the selection of internal standards during the development of desorption/ionization assays for drug quantification in biological matrices : a practical example / Margaux Fresnais, Seda Karabulut, Yasmin Abou Zeed, Johannes Ungermann, Julia Benzel, Kristian W. Pa… , 21 January 2022. - 13 S.
In: Molecules, ISSN 1420-3049. 27(2022), 3, Artikel-ID 690, Seite 1-13
DOI: 10.3390/molecules27030690
- Dittes, Christine: Local and systemic therapy of recurrent medulloblastomas in children and adolescents : results of the P-HIT-REZ 2005 study / Christine Gaab, Jonas E. Adolph, Stephan Tippelt, Ruth Mikasch, Denise Obrecht, Martin Mynarek, Stef… , 18 January 2022. - 24 S.
In: Cancers, ISSN 2072-6694. 14(2022), 3, Artikel-ID 471, Seite 1-24
DOI: 10.3390/cancers14030471
- Cidre-Aranaz, Florencia: Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma / Florencia Cidre-Aranaz, Jing Li, Tilman L. B. Hölting, Martin F. Orth, Roland Imle, Stefanie Kutschm… , 02 January 2022. - 7 S.
In: Molecular cancer, ISSN 1476-4598. 21(2022), Artikel-ID 1, Seite 1-7
DOI: 10.1186/s12943-021-01470-z
- Pfister, Stefan: A summary of the inaugural WHO classification of pediatric tumors : transitioning from the optical into the molecular era / Stefan M. Pfister, Miguel Reyes-Múgica, John K. C. Chan, Henrik Hasle, Alexander J. Lazar, Sabrina R… , 2022. - 25 S.
In: Cancer discovery, ISSN 2159-8290. 12(2022), 2 vom: Feb., Seite 331-355
DOI: 10.1158/2159-8290.CD-21-1094
- Miele, Evelina: Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth / Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi,… , February 2021. - 20 S. : Illustrationen
In: Molecular oncology, ISSN 1878-0261. 15(2021), 2 vom: Feb., Seite 523-542
DOI: 10.1002/1878-0261.12800
- Sievers, Philipp: GOPC : ROS1 and other ROS1 fusions represent a rare but recurrent drug target in a variety of glioma types / Philipp Sievers, Damian Stichel, Martin Sill, Daniel Schrimpf, Dominik Sturm, Florian Selt, Jonas Ec… , 18 September 2021. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 6, Seite 1065-1069
DOI: 10.1007/s00401-021-02369-1
- Kölsche, Christian: Intimal sarcomas and undifferentiated cardiac sarcomas carry mutually exclusive MDM2, MDM4, and CDK6 amplifications and share a common DNA methylation signature / Christian Koelsche, Jamal K. Benhamida, Felix K. F. Kommoss, Damian Stichel, David T. W. Jones, Stef… , December 2021. - 8 S.
In: Modern pathology, ISSN 1530-0285. 34(2021), 12 vom: Dez., Seite 2122-2129
DOI: 10.1038/s41379-021-00874-y
- Suwala, Abigail Kora: Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1 / Abigail K. Suwala, Damian Stichel, Daniel Schrimpf, Sybren L.N. Maas, Martin Sill, Hildegard Dohmen,… , 19 April 2021. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 1, Seite 179-189
DOI: 10.1007/s00401-021-02302-6
- Kommoss, Felix: Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract : evidence for a distinct DICER1-associated subgroup / Felix K.F. Kommoss, Damian Stichel, Jaume Mora, Manel Esteller, David T.W. Jones, Stefan M. Pfister,… , 12 April 2021. - 12 S.
In: Modern pathology, ISSN 1530-0285. 34(2021), 8, Seite 1558-1569
DOI: 10.1038/s41379-021-00804-y
- Simovic, Milena: Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model / Milena Simovic, Michiel Bolkestein, Mahmoud Moustafa, John K L Wong, Verena Körber, Sarah Benedetto,… , 28 May 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 12, Seite 2028-2041
DOI: 10.1093/neuonc/noab127
- Ballabio, Claudio: Notch1 switches progenitor competence in inducing medulloblastoma / Claudio Ballabio, Matteo Gianesello, Chiara Lago, Konstantin Okonechnikov, Marica Anderle, Giuseppe … , 23 Jun 2021. - 13 S.
In: Science advances, ISSN 2375-2548. 7(2021), 26, Artikel-ID eabd2781, Seite 1-13
DOI: 10.1126/sciadv.abd2781
- Deng, Maximilian: Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B / Maximilian Y. Deng, Dominik Sturm, Elke Pfaff, Martin Sill, Damian Stichel, Gnana Prakash Balasubram… , 20 September 2021. - 11 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 5530, Seite 1-11
DOI: 10.1038/s41467-021-25708-y
- Adachi, Toma: Notch signaling between cerebellar granule cell progenitors / Toma Adachi, Satoshi Miyashita, Mariko Yamashita, Mana Shimoda, Konstantin Okonechnikov, Lukas Chave… , March 24, 2021. - 18 S.
In: eNeuro, ISSN 2373-2822. 8(2021), 3 vom: Mai/Juni, Seite 1-18
DOI: 10.1523/ENEURO.0468-20.2021
- Panwalkar, Pooja: Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas / Pooja Panwalkar, Benita Tamrazi, Derek Dang, Chan Chung, Stefan Sweha, Siva Kumar Natarajan, Matthew… , 6 Oct 2021. - 13 S.
In: Science translational medicine, ISSN 1946-6242. 13(2021), 614, Artikel-ID eabc0497, Seite 1-13
DOI: 10.1126/scitranslmed.abc0497
- Sepp, Mari: Cellular development and evolution of the mammalian cerebellum [research data] / Mari Sepp, Kevin Leiss, Ioannis Sarropoulos, Florent Murat, Konstantin Okonechnikov, Piyush Joshi, E… . -
Heidelberg: Universität, 2021-12-03. - 1 Online-Ressource (87 Files)
DOI: 10.11588/data/QDOC4E
- Sievers, Philipp: Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors / Philipp Sievers, Sophie C. Henneken, Christina Blume, Martin Sill, Daniel Schrimpf, Damian Stichel, … , 05 August 2021. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 5, Seite 827-839
DOI: 10.1007/s00401-021-02356-6
- Kirches, Elmar: Molecular profiling of pediatric meningiomas shows tumor characteristics distinct from adult meningiomas / Elmar Kirches, Felix Sahm, Andrey Korshunov, Christina Bluecher, Natalie Waldt, Siegfried Kropf, Dan… , 08 September 2021. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 142(2021), 5, Seite 873-886
DOI: 10.1007/s00401-021-02351-x
- Benzel, Julia: Investigating the central nervous system disposition of actinomycin D : implementation and evaluation of cerebral microdialysis and brain tissue measurements supported by UPLC-MS/MS quantification / Julia Benzel, Gzona Bajraktari-Sylejmani, Philipp Uhl, Abigail Davis, Sreenath Nair, Stefan M. Pfist… , 17 September 2021. - 16 S.
In: Pharmaceutics, ISSN 1999-4923. 13(2021), 9, special issue, Artikel-ID 1498, Seite 1-16
DOI: 10.3390/pharmaceutics13091498
- Adolph, Jonas E.: Local and systemic therapy of recurrent ependymoma in children and adolescents : short- and long-term results of the E-HIT-REZ 2005 study / Jonas E. Adolph, Gudrun Fleischhack, Ruth Mikasch, Julia Zeller, Monika Warmuth-Metz, Brigitte Bison… , 2021. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 6, Seite 1012-1023
DOI: 10.1093/neuonc/noaa276
- Daub, Joséphine: A systematic analysis of genetic interactions and their underlying biology in childhood cancer / Josephine T. Daub, Saman Amini, Denise J.E. Kersjes, Xiaotu Ma, Natalie Jäger, Jinghui Zhang, Stefan… , 06 October 2021. - 12 S.
In: Communications biology, ISSN 2399-3642. 4(2021), Artikel-ID 1139, Seite 1-12
DOI: 10.1038/s42003-021-02647-4
- Louis, David N.: The 2021 WHO Classification of Tumors of the Central Nervous System : a summary / David N. Louis, Arie Perry, Pieter Wesseling, Daniel J. Brat, Ian A. Cree, Dominique Figarella-Brang… , 29 June 2021. - 21 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 8, Seite 1231-1251
DOI: 10.1093/neuonc/noab106
- Baroni, Lorena V.: Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q / Lorena V. Baroni, Lakshmikirupa Sundaresan, Ayala Heled, Hallie Coltin, Kristian W. Pajtler, Tong Li… , 13 February 2021. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 8, Seite 1360-1370
DOI: 10.1093/neuonc/noab034
- Hoff, Katja von: Therapeutic implications of improved molecular diagnostics for rare CNS embryonal tumor entities : results of an international, retrospective study / Katja von Hoff, Christine Haberler, Felix Schmitt-Hoffner, Elizabeth Schepke, Teresa de Rojas, Sandr… , 02 June 2021. - 15 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 9, Seite 1597-1611
DOI: 10.1093/neuonc/noab136
- Zheng, Tuyu: Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas / Tuyu Zheng, David R. Ghasemi, Konstantin Okonechnikov, Andrey Korshunov, Martin Sill, Kendra K. Maas… , April 20, 2021. - 18 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 9, Seite 2230-2247
DOI: 10.1158/2159-8290.CD-20-0963
- Hau, Peter: Development of randomized trials in adults with medulloblastoma : the example of EORTC 1634-BTG/NOA-23 / Peter Hau, Didier Frappaz, Elizabeth Hovey, Martin G. McCabe, Kristian W. Pajtler, Benedikt Wiestler… , 9 July 2021. - 20 S.
In: Cancers, ISSN 2072-6694. 13(2021), 14, special issue, Artikel-ID 3451, Seite 1-20
DOI: 10.3390/cancers13143451
- Arabzade, Amir: ZFTA-RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma / Amir Arabzade, Yanhua Zhao, Srinidhi Varadharajan, Hsiao-Chi Chen, Selin Jessa, Bryan Rivas, Austin … , September 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 9, Seite 2200-2215
DOI: 10.1158/2159-8290.CD-20-1066
- Korshunov, Andrey: Integrated molecular analysis of adult Sonic Hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator / Andrey Korshunov, Konstantin Okonechnikov, Damian Stichel, Marina Ryzhova, Daniel Schrimpf, Felix Sa… , 16 February 2021. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 9, Seite 1576-1585
DOI: 10.1093/neuonc/noab031
- Maas, Sybren L. N.: Integrated molecular-morphologic meningioma classification : a multicenter retrospective analysis, retrospectively and prospectively validated / Sybren L.N. Maas, Damian Stichel, Thomas Hielscher, Philipp Sievers, Anna S. Berghoff, Daniel Schrim… , October 7, 2021. - 14 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 34, Seite 3839-3852
DOI: 10.1200/JCO.21.00784
- Suwala, Abigail Kora: Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis / Abigail K. Suwala, Damian Stichel, Daniel Schrimpf, Matthias Kloor, Annika K. Wefers, Annekathrin Re… , 2021. - 16 S.
In: Acta neuropathologica, ISSN 1432-0533. 141(2021), 1, Seite 85-100
DOI: 10.1007/s00401-020-02243-6
- Vassal, Gilles: International consensus on minimum preclinical testing requirements for the development of innovative therapies for children and adolescents with cancer / Gilles Vassal, Peter J. Houghton, Stefan M. Pfister, Malcolm A. Smith, Huib N. Caron, Xiao-Nan Li, D… , June 9, 2021. - 7 S.
In: Molecular cancer therapeutics, ISSN 1538-8514. 20(2021), 8 vom: Aug., Seite 1462-1468
DOI: 10.1158/1535-7163.MCT-20-0394
- Young, Matthew D.: Single cell derived mRNA signals across human kidney tumors / Matthew D. Young, Thomas J. Mitchell, Lars Custers, Thanasis Margaritis, Francisco Morales-Rodriguez… , 23 June 2021. - 19 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 3896, Seite 1-19
DOI: 10.1038/s41467-021-23949-5
- Tilburg, Cornelis M. van: The pediatric precision oncology INFORM registry : clinical outcome and benefit for patients with very high-evidence targets / Cornelis M. van Tilburg, Elke Pfaff, Kristian W. Pajtler, Karin P. S. Langenberg, Petra Fiesel, Barb… , August 9, 2021. - 16 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 11, Seite 2764-2779
DOI: 10.1158/2159-8290.CD-21-0094
- Maaß, Kendra K.: From sampling to sequencing : a liquid biopsy pre-analytic workflow to maximize multi-layer genomic information from a single tube / Kendra K. Maass, Paulina S. Schad, Agnes M.E. Finster, Pitithat Puranachot, Fabian Rosing, Tatjana W… , 15 June 2021. - 25 S.
In: Cancers, ISSN 2072-6694. 13(2021), 12, Artikel-ID 3002, Seite 1-25
DOI: 10.3390/cancers13123002
- Sarropoulos, Ioannis: Developmental and evolutionary dynamics of cis-regulatory elements in mouse cerebellar cells / Ioannis Sarropoulos, Mari Sepp, Robert Frömel, Kevin Leiss, Nils Trost, Evgeny Leushkin, Konstantin … , 29 July 2021. - 11 S.
In: Science, ISSN 1095-9203. 373(2021), 6558, Artikel-ID eabg4696, Seite 1-11
DOI: 10.1126/science.abg4696
- Sauter, Max: Bioanalysis of selinexor in mouse plasma micro-samples utilizing UPLC-MS/MS / Max Sauter, Kathrin I. Foerster, Julia Benzel, Stefan Pfister, Kristian W. Pajtler, Walter E. Haefel… , 20 May 2021. - 6 S.
In: Journal of chromatography, ISSN 1873-376X. 1176(2021), Artikel-ID 122781, Seite 1-6
DOI: 10.1016/j.jchromb.2021.122781
- Sievers, Philipp: A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR / Philipp Sievers, Martin Sill, Daniel Schrimpf, Damian Stichel, David E. Reuss, Dominik Sturm, Jürgen… , 2021. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 1, Seite 34-43
DOI: 10.1093/neuonc/noaa251
- Albert, Thomas: An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma / Thomas K. Albert, Marta Interlandi, Martin Sill, Monika Graf, Natalia Moreno, Kerstin Menck, Astrid … , 2021. - 13 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 4 vom: Apr., Seite 586-598
DOI: 10.1093/neuonc/noaa254
- Sievers, Philipp: Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1 / Philipp Sievers, Martin Sill, Christina Blume, Arnault Tauziede-Espariat, Daniel Schrimpf, Damian St… , 2021. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 141(2021), 2, Seite 281-290
DOI: 10.1007/s00401-020-02247-2
- Schmitt-Hoffner, Felix: FOXR2 stabilizes MYCN protein and identifies non-MYCN-amplified neuroblastoma patients with unfavorable outcome / Felix Schmitt-Hoffner, Sjoerd van Rijn, Umut H. Toprak, Monika Mauermann, Felix Rosemann, Anke Heit-… , June 10, 2021. - 12 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 29 vom: Okt., Seite 3217-3228
DOI: 10.1200/JCO.20.02540
- Ecker, Jonas: Reduced chromatin binding of MYC is a key effect of HDAC inhibition in MYC amplified medulloblastoma / Jonas Ecker, Venu Thatikonda, Gianluca Sigismondo, Florian Selt, Gintvile Valinciute, Ina Oehme, Car… , 2021. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 2 vom: Feb., Seite 226-239
DOI: 10.1093/neuonc/noaa191
- Pfaff, Elke: NTRK alterations in pediatric high-risk malignancies identified through European clinical sequencing programs constitute promising drug targets / Elke Pfaff, Tiphaine Adam de Beaumais, Antonin Marchais, Cornelis M. van Tilburg, Mirjam Blattner-Jo… , February 26, 2021. - 5 S.
In: JCO precision oncology, ISSN 2473-4284. 5(2021), Seite 450-454
DOI: 10.1200/PO.20.00417
- Kumar, Rahul: Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma / Rahul Kumar, PhD; Kyle S. Smith, PhD; Maximilian Deng, MD; Colt Terhune, BA; Giles W. Robinson, MD; … , January 27, 2021. - 18 S.
In: Journal of clinical oncology, ISSN 1527-7755. 39(2021), 7, Seite 807-821
DOI: 10.1200/JCO.20.01359
- Behjati, Sam: Maturation block in childhood cancer / Sam Behjati, Richard J. Gilbertson, and Stefan M. Pfister, February 15, 2021. - 3 S.
In: Cancer discovery, ISSN 2159-8290. 11(2021), 3, Seite 542-544
DOI: 10.1158/2159-8290.CD-20-0926
- Fresnais, Margaux: Rapid MALDI-MS assays for drug quantification in biological matrices : lessons learned, new developments, and future perspectives / Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W. … , 26 February 2021. - 19 S.
In: Molecules, ISSN 1420-3049. 26(2021), 5, Artikel-ID 1281, Seite 1-19
DOI: 10.3390/molecules26051281
- Kölsche, Christian: Sarcoma classification by DNA methylation profiling / Christian Koelsche, Daniel Schrimpf, Damian Stichel, Martin Sill, Felix Sahm, David E. Reuss, Mirjam… , 21 January 2021. - 10 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 498, Seite 1-10
DOI: 10.1038/s41467-020-20603-4
- Korshunov, Andrey: Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation / Andrey Korshunov, Konstantin Okonechnikov, Felix Schmitt-Hoffner, Marina Ryzhova, Felix Sahm, Damian… , 03 February 2021. - 12 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 9(2021), Artikel-ID 20, Seite 1-12
DOI: 10.1186/s40478-021-01118-5
- Endersby, Raelene: Small-molecule screen reveals synergy of cell cycle checkpoint kinase inhibitors with DNA-damaging chemotherapies in medulloblastoma / Raelene Endersby, Jacqueline Whitehouse, Allison Pribnow, Mani Kuchibhotla, Hilary Hii, Brooke Carli… , 20 January 2021
In: Science translational medicine, ISSN 1946-6242. 13(2021), 577, Artikel-ID eaba7401, Seite 1-16
DOI: 10.1126/scitranslmed.aba7401
- Stainczyk, Sabine: Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome / Sabine A. Hartlieb, Lina Sieverling, Michal Nadler-Holly, Matthias Ziehm, Umut H. Toprak, Carl Herrm… , 24 February 2021. - 18 S.
In: Nature Communications, ISSN 2041-1723. 12(2021), Artikel-ID 1269, Seite 1-18
DOI: 10.1038/s41467-021-21247-8
- Haag, Daniel: H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model / Daniel Haag, Norman Mack, Patricia Benites Goncalves da Silva, Britta Statz, Jessica Clark, Koji Tan… , 4 February 2021. - 29 S.
In: Cancer cell, ISSN 1878-3686. 39(2021), 3, Seite 407-422.e13
DOI: 10.1016/j.ccell.2021.01.005
- Gartlgruber, Moritz: Super enhancers define regulatory subtypes and cell identity in neuroblastoma / Moritz Gartlgruber, Ashwini Kumar Sharma, Andrés Quintero, Daniel Dreidax, Selina Jansky, Young-Gyu … , 2021. - 15 S.
In: Nature cancer, ISSN 2662-1347. 2(2021), 1, Seite 114-128
DOI: 10.1038/s43018-020-00145-w
- Fittall, Matthew W.: Drivers underpinning the malignant transformation of giant cell tumour of bone / Matthew W Fittall, Iben Lyskjær, Peter Ellery, Patrick Lombard, Jannat Ijaz, Anna-Christina Strobl, … , December 2020. - 8 S. : Illustrationen
In: The journal of pathology, ISSN 1096-9896. 252(2020), 4 vom: Dez., Seite 433-440
DOI: 10.1002/path.5537
- Selt, Florian: Response to trametinib treatment in progressive pediatric low-grade glioma patients / Florian Selt, Cornelis M. van Tilburg, Brigitte Bison, Philipp Sievers, Inga Harting, Jonas Ecker, K… , 7 October 2020. - 12 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 149(2020) vom: Sept., Seite 499-510
DOI: 10.1007/s11060-020-03640-3
- Sill, Martin: Molecular tumor classification using DNA methylome analysis / Martin Sill, Christoph Plass, Stefan M. Pfister and Daniel B. Lipka, 3 July 2020. - 9 S.
In: Human molecular genetics, ISSN 1460-2083. 29(2020), R2, Seite R205-R213
DOI: 10.1093/hmg/ddaa147
- Rusert, Jessica M.: Functional precision medicine identifies new therapeutic candidates for medulloblastoma / Jessica M. Rusert, Edwin F. Juarez, Sebastian Brabetz, James Jensen, Alexandra Garancher, Lianne Q. … , October 12, 2020. - 15 S.
In: Cancer research, ISSN 1538-7445. 80(2020), 23, Seite 5393-5407
DOI: 10.1158/0008-5472.CAN-20-1655
- Chen, Carol C. L.: Histone H3.3G34-mutant interneuron progenitors Co-opt PDGFRA for gliomagenesis / Carol C.L. Chen, Shriya Deshmukh, Selin Jessa, Djihad Hadjadj, Véronique Lisi, Augusto Faria Andrade… , November 30, 2020. - 38 S.
In: Cell, ISSN 1097-4172. 183(2020,6) Seite 1617-1633, e1-e11, 38 Seiten
DOI: 10.1016/j.cell.2020.11.012
- Sievers, Philipp: CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas / Philipp Sievers, Thomas Hielscher, Daniel Schrimpf, Damian Stichel, David E. Reuss, Anna S. Berghoff… , 08 July 2020. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 140(2020), 3, Seite 409-413
DOI: 10.1007/s00401-020-02188-w
- Dejaegher, Joost: DNA methylation based glioblastoma subclassification is related to tumoral T-cell infiltration and patient survival / Joost Dejaegher, Lien Solie, Zoé Hunin, Raf Sciot, David Capper, Christin Siewert, Sofie Van Cauter,… , 2021. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 23(2021), 2 vom: Feb., Seite 240-250
DOI: 10.1093/neuonc/noaa247
- Tilburg, Cornelis M. van: INFORM2 NivEnt : the first trial of the INFORM2 biomarker driven phase I/II trial series : the combination of nivolumab and entinostat in children and adolescents with refractory high-risk malignancies / Cornelis M. van Tilburg, Ruth Witt, Melanie Heiss, Kristian W. Pajtler, Christoph Plass, Isabel Posc… , 05 June 2020. - 12 S.
In: BMC cancer, ISSN 1471-2407. 20(2020) vom: Juni, Artikel-ID 523, Seite 1-12
DOI: 10.1186/s12885-020-07008-8
- Aichmüller, Christian Felix: Pilocytic astrocytoma demethylation and transcriptional landscapes link bZIP transcription factors to immune response / Christian F Aichmüller, Murat Iskar, David TW Jones, Andrey Korshunov, Bernhard Radlwimmer, Marcel K… , 13 February 2020. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 9, Seite 1327-1338
DOI: 10.1093/neuonc/noaa035
- Jabarkheel, Rashad: Molecular correlates of cerebellar mutism syndrome in medulloblastoma / Rashad Jabarkheel, Nisreen Amayiri, Derek Yecies, Yuhao Huang, Sebastian Toescu, Liana Nobre, Donald… , 23 August 2019. - 8 S.
In: Neuro-Oncology, ISSN 1523-5866. 22(2020), 2, Seite 290-297
DOI: 10.1093/neuonc/noz158
- Usta, Diren: A cell-based MAPK reporter assay reveals synergistic MAPK pathway activity suppression by MAPK inhibitor combination in BRAF-driven pediatric low-grade glioma cells / Diren Usta, Romain Sigaud, Juliane L. Buhl, Florian Selt, Viktoria Marquardt, David Pauck, Jennifer … , May 25, 2020. - 14 S.
In: Molecular cancer therapeutics, ISSN 1538-8514. 19(2020), 8, Seite 1737-1750
DOI: 10.1158/1535-7163.MCT-19-1021
- Mynarek, Martin: Nonmetastatic medulloblastoma of early childhood : results from the prospective clinical trial HIT-2000 and an extended validation cohort / Martin Mynarek, MD; Katja von Hoff, MD; Torsten Pietsch, MD; Holger Ottensmeier, PhD; Monika Warmuth… , April 24, 2020. - 13 S.
In: Journal of clinical oncology, ISSN 1527-7755. 38(2020), 18, Seite 2028-2040
DOI: 10.1200/JCO.19.03057
- Fresnais, Margaux: Rapid and sensitive quantification of osimertinib in human plasma using a fully validated MALDI-IM-MS/MS assay / Margaux Fresnais, André Roth, Kathrin I. Foerster, Dirk Jäger, Stefan M. Pfister, Walter E. Haefeli,… , 14 July 2020. - 18 S.
In: Cancers, ISSN 2072-6694. 12(2020,7) Artikel-Nummer 1897, 18 Seiten
DOI: 10.3390/cancers12071897
- Schubert, Nil A.: Systematic target actionability reviews of preclinical proof-of-concept papers to match targeted drugs to paediatric cancers / Nil A. Schubert, Caitlin D. Lowery, Guillaume Bergthold, Jan Koster, Thomas F. Eleveld, Ana Rodrígue… , 27 March 2020. - 14 S.
In: European journal of cancer, ISSN 1879-0852. 130(2020), Seite 168-181
DOI: 10.1016/j.ejca.2020.01.027
- Clarke, Matthew: Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes / Matthew Clarke, Alan Mackay, Britta Ismer, Jessica C. Pickles, Ruth G. Tatevossian, Scott Newman, Te… , April 1, 2020. - 22 S.
In: Cancer discovery, ISSN 2159-8290. 10(2020), 7, Seite 942-963
DOI: 10.1158/2159-8290.CD-19-1030
- Gojo, Johannes: Single-cell RNA-seq reveals cellular hierarchies and impaired developmental trajectories in pediatric ependymoma / Johannes Gojo, Bernhard Englinger, Li Jiang, Jens M. Hübner, McKenzie L. Shaw, Olivia A. Hack, Sibyl… , July 13, 2020. - 25 S.
In: Cancer cell, ISSN 1878-3686. 38(2020), 1, Seite 44-59.e9
DOI: 10.1016/j.ccell.2020.06.004
- Kutscher, Lena: Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation / Lena M. Kutscher, Konstantin Okonechnikov, Nadja V. Batora, Jessica Clark, Patricia B. G. Silva, Mik… , August 20, 2020. - 16 S.
In: Genes & development, ISSN 1549-5477. 34(2020), 17/18, Seite 1161-1176
DOI: 10.1101/gad.337584.120
- Waszak, Sebastian Martin: Germline elongator mutations in Sonic Hedgehog medulloblastoma / Sebastian M. Waszak, Robinson Giles W, Brian L. Gudenas, Kyle S. Smith, Antoine Forget, Marija Kojic… , 01 April 2020. - 21 S.
In: Nature, ISSN 1476-4687. 580(2020), 7803, Seite 396-401
DOI: 10.1038/s41586-020-2164-5
- Kommoss, Felix: DNA methylation-based profiling of uterine neoplasms : a novel tool to improve gynecologic cancer diagnostics / Felix K. F. Kommoss, Damian Stichel, Daniel Schrimpf, Mark Kriegsmann, Basile Tessier-Cloutier, Alin… , 2020. - 8 S.
In: Journal of cancer research and clinical oncology, ISSN 1432-1335. 146(2020), 1, Seite 97-104
DOI: 10.1007/s00432-019-03093-w
- Hong, David S.: Larotrectinib in patients with TRK fusion-positive solid tumours : a pooled analysis of three phase 1/2 clinical trials / David S Hong, Steven G DuBois, Shivaani Kummar, Anna F Farago, Catherine M Albert, Kristoffer S Rohr… , [April 2020]. - 10 S. : Diagramme
In: The lancet, ISSN 1474-5488. 21(2020), 4, Seite 531-540
DOI: 10.1016/S1470-2045(19)30856-3
- Deng, Maximilian: Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC) - a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14 / M.Y. Deng, M. Sill, D. Sturm, D. Stichel, H. Witt, J. Ecker, A. Wittmann, J. Schittenhelm, M. Ebinge… , 2020
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 46(2020), 5, Seite 422-430
DOI: 10.1111/nan.12590
- Fresnais, Margaux: Rapid and sensitive drug quantification in tissue sections using matrix assisted laser desorption Ionization-Ion mobility-mass spectrometry profiling / Margaux Fresnais, Alexander Muck, Marius Majewsky, Britta Statz, Sonja Krausert, Julia Benzel, David… , January 23, 2020. - 10 S.
In: Journal of the American Society for Mass Spectrometry, ISSN 1879-1123. 31(2020), 3, Seite 742-751
DOI: 10.1021/jasms.0c00005
- Sievers, Philipp: YAP1-fusions in pediatric NF2-wildtype meningioma / Philipp Sievers, Jason Chiang, Daniel Schrimpf, Damian Stichel, Nagarajan Paramasivam, Martin Sill, … , 2020. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 1, Seite 215-218
DOI: 10.1007/s00401-019-02095-9
- Pfaff, Elke: Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations / Elke Pfaff, Christian Aichmüller, Martin Sill, Damian Stichel, Matija Snuderl, Matthias A. Karajanni… , [2020]. - 15 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 2, Seite 243-257
DOI: 10.1007/s00401-019-02101-0
- Tilburg, Cornelis M. van: Phase I/II intra-patient dose escalation study of vorinostat in children with relapsed solid tumor, lymphoma, or leukemia / Cornelis M. van Tilburg, Till Milde, Ruth Witt, Jonas Ecker, Thomas Hielscher, Angelika Seitz, Jens-… , 10 December 2019. - 15 S.
In: Clinical epigenetics, ISSN 1868-7083. 11(2019) Artikel-Nummer 188, 15 Seiten
DOI: 10.1186/s13148-019-0775-1
- Ghasemi, David R.: MYCN amplification drives an aggressive form of spinal ependymoma / David R. Ghasemi, Martin Sill, Konstantin Okonechnikov, Andrey Korshunov, Stephen Yip, Peter W. Schu… , 14 August 2019. - 15 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 6, Seite 1075-1089
DOI: 10.1007/s00401-019-02056-2
- Jaju, Alok: MRI features of histologically diagnosed supratentorial primitive neuroectodermal tumors and pineoblastomas in correlation with molecular diagnoses and outcomes : a report from the Children's Oncology Group ACNS0332 trial / A. Jaju, E.I. Hwang, M. Kool, D. Capper, L. Chavez, S. Brabetz, C. Billups, Y. Li, M. Fouladi, R.J. … , 1 Nov 2019. - 8 S.
In: American journal of neuroradiology, ISSN 1936-959X. 40(2019), 11, Seite 1796-1803
DOI: 10.3174/ajnr.A6253
- Stock, Annika: Imaging characteristics of wingless pathway subgroup medulloblastomas : results from the German HIT/SIOP-trial cohort / A. Stock, M. Mynarek, T. Pietsch, S.M. Pfister, S.C. Clifford, T. Goschzik, D. Sturm, E.C. Schwalbe,… , 1 Nov 2019. - 7 S.
In: American journal of neuroradiology, ISSN 1936-959X. 40(2019), 11, Seite 1811-1817
DOI: 10.3174/ajnr.A6286
- Hovestadt, Volker: Medulloblastomics revisited : biological and clinical insights from thousands of patients / Volker Hovestadt, Olivier Ayrault, Fredrik J. Swartling, Giles W. Robinson, Stefan M. Pfister, and P… , 09 December 2019. - 13 S.
In: Nature reviews, ISSN 1474-1768. 20(2020), 1, Seite 42-56
DOI: 10.1038/s41568-019-0223-8
- Rojas, Teresa de: EORTC SPECTA-AYA : a unique molecular profiling platform for adolescents and young adults with cancer in Europe / Teresa de Rojas, Bernd Kasper, Winette Van der Graaf, Stefan M. Pfister, Franck Bielle, Teresa Ribal… , 29 August 2019
In: International journal of cancer, ISSN 1097-0215. 147(2020), 4, Seite 1180-1184
DOI: 10.1002/ijc.32651
- Begemann, Matthias: Germline GPR161 mutations predispose to pediatric medulloblastoma / Matthias Begemann, PhD; Sebastian M. Waszak, PhD; Giles W. Robinson, MD; Natalie Jäger, PhD; Tanvi… , October 14, 2019. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 38(2019), 1, Seite 43-50
DOI: 10.1200/JCO.19.00577
- Dutzmann, Christina M.: Ein Update zum Li-Fraumeni-Syndrom / C. M. Dutzmann, J. Vogel, C. P. Kratz, K. W. Pajtler, S. M. Pfister, B. B. Dörgeloh, 11 September 2019. - 8 S.
In: Der Pathologe, ISSN 1432-1963. 40(2019), 6, Seite 592-599
DOI: 10.1007/s00292-019-00657-y
- Pickles, Jessica C.: DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment : a population-based study / Jessica C Pickles, Amy R Fairchild, Thomas J Stone, Lorelle Brownlee, Ashirwad Merve, Shireena A Yas… , 2020. - 9 S.
In: The lancet child & adolescent health, ISSN 2352-4650. 4(2020), 2, Seite 121-130
DOI: 10.1016/S2352-4642(19)30342-6
- Sievers, Philipp: Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation / Philipp Sievers, Daniel Schrimpf, Damian Stichel, David E. Reuss, Martin Hasselblatt, Christian Hage… , [2020]. - 4 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 2, Seite 403-406
DOI: 10.1007/s00401-019-02097-7
- Wefers, Annika K.: Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course / Annika K. Wefers, Damian Stichel, Daniel Schrimpf, Roland Coras, Mélanie Pages, Arnault Tauziède-Esp… , 2020. - 17 S.
In: Acta neuropathologica, ISSN 1432-0533. 139(2020), 1, Seite 193-209
DOI: 10.1007/s00401-019-02078-w
- SYS-GLIO: Systembasierte Vorhersagen für das biologische und klinische Verhalten von Gliomen : Abschlussbericht : Laufzeit des Vorhabens: 01.03.2015-28.02.2018 (verlängert bis 31.12.2018) : Berichtszeitraum: 01.03.2015-31.12.2018 / Zuwendungsempfänger: Prof. Dr. Peter Lichter, Leiter der Abteilung Molekulare Genetik, DKFZ; Prof. D… . -
Heidelberg: DKFZ, [2019?]. - 1 Online-Ressource (8 Seiten, 95,42 KB)
DOI: 10.2314/KXP:1689649704
- Kirches, Elmar: Pediatric meningiomas are characterized by distinct methylation profiles different from adult meningiomas / Elmar Kirches, Felix Sahm, Christina Blücher, Svenja Boeckhoff, Ulrich Schüller, Jens Schittenhelm, … , 23 April 2019
In: Neuro-Oncology, ISSN 1523-5866. Bd. 21.2019, Suppl. 2, GENE-13, Seite ii83-ii84
DOI: 10.1093/neuonc/noz036.084
- Okonechnikov, Konstantin: Probing medulloblastoma initiation at the single-cell level / Konstantin Okonechnikov, Stefan M. Pfister, Lena M. Kutscher, 28 October 2019. - 3 S.
In: Trends in cancer, ISSN 2405-8025. 5(2019), 12, Seite 759-761
DOI: 10.1016/j.trecan.2019.10.002
- Chun, Hye-Jung E.: Identification and analyses of extra-cranial and cranial rhabdoid tumor molecular subgroups reveal tumors with cytotoxic T cell infiltration / Hye-Jung E. Chun, Pascal D. Johann, Katy Milne, Marc Zapatka, Annette Buellesbach, Naveed Ishaque, M… , 7 November, 2019. - 24 S.
In: Cell reports, ISSN 2211-1247. 29(2019), 8, Seite 2338-2354.e1-e7
DOI: 10.1016/j.celrep.2019.10.013
- Aldape, Kenneth: Challenges to curing primary brain tumours / Kenneth Aldape, Kevin M. Brindle, Louis Chesler, Rajesh Chopra, Amar Gajjar, Mark R. Gilbert, Nichol… , 07 February 2019. - 12 S.
In: Nature reviews, ISSN 1759-4782. 16(2019), 8, Seite 509-520
DOI: 10.1038/s41571-019-0177-5
- Aldape, Kenneth: Reply to ‘assembling the brain trust : the multidisciplinary imperative in neuro-oncology’ / Kenneth Aldape, Kevin M. Brindle, Louis Chesler, Rajesh Chopra, Amar Gajjar, Mark R. Gilbert, Nichol… , 31 May 2019. - 2 S.
In: Nature reviews, ISSN 1759-4782. 16(2019), 8, Seite 522-523
DOI: 10.1038/s41571-019-0236-y
- Jones, David T. W.: Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours / David T.W. Jones, Ana Banito, Thomas G.P. Grünewald, Michelle Haber, Natalie Jäger, Marcel Kool, Til… , 12 July 2019. - 19 S.
In: Nature reviews, ISSN 1474-1768. 19(2019), 8, Seite 420-438
DOI: 10.1038/s41568-019-0169-x
- Franceschi, Enrico: EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma / Enrico Franceschi, Silvia Hofer, Alba A Brandes, Didier Frappaz, Rolf-Dieter Kortmann, Jacoline Brom… , 2 December 2019. - 14 S.
In: The lancet, ISSN 1474-5488. 20(2019), 12, Seite e715-e728
DOI: 10.1016/S1470-2045(19)30669-2
- Sharma, Tanvi: Second-generation molecular subgrouping of medulloblastoma : an international meta-analysis of Group 3 and Group 4 subtypes / Tanvi Sharma, Edward C. Schwalbe, Daniel Williamson, Martin Sill, Volker Hovestadt, Martin Mynarek, … , 10 May 2019. - 18 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 309-326
DOI: 10.1007/s00401-019-02020-0
- Paramasivam, Nagarajan: Mutational patterns and regulatory networks in epigenetic subgroups of meningioma / Nagarajan Paramasivam, Daniel Hübschmann, Umut H. Toprak, Naveed Ishaque, Marian Neidert, Daniel Sch… , 2019. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 295-308
DOI: 10.1007/s00401-019-02008-w
- Reinhardt, Annekathrin: Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities / Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Christian Koelsche, Annika K. Wefers, Azadeh… , 28 October 2019. - 12 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 7(2019), Artikel-ID 163, Seite 1-12
DOI: 10.1186/s40478-019-0801-8
- Korshunov, Andrey: Molecular progression of SHH-activated medulloblastomas / Andrey Korshunov, Konstantin Okonechnikov, Felix Sahm, Marina Ryzhova, Damian Stichel, Philipp Sieve… , 27 April 2019. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 2, Seite 327-330
DOI: 10.1007/s00401-019-02022-y
- Suzuki, Hiromichi: Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma / Hiromichi Suzuki, Sachin A. Kumar, Shimin Shuai, Ander Diaz-Navarro, Ana Gutierrez-Fernandez, Pasqua… , 10 October 2019. - 5 S.
In: Nature, ISSN 1476-4687. 574(2019), 7780, Seite 707-711
DOI: 10.1038/s41586-019-1650-0
- Stichel, Damian: Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions / Damian Stichel, Daniel Schrimpf, Belén Casalini, Jochen Meyer, Annika K. Wefers, Philipp Sievers, An… , 05 July 2019. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 138(2019), 5, Seite 827-835
DOI: 10.1007/s00401-019-02039-3
- Hübner, Jens-Martin: EZHIP/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma / Jens-Martin Hübner, Torsten Müller, Dimitris N Papageorgiou, Monika Mauermann, Jeroen Krijgsveld, Ro… , 29 April 2019. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 21(2019), 7, Seite 878-889
DOI: 10.1093/neuonc/noz058
- Schramm, Kathrin: DECIPHER pooled shRNA library screen identifies PP2A and FGFR signaling as potential therapeutic targets for diffuse intrinsic pontine gliomas / Kathrin Schramm, Murat Iskar, Britta Statz, Natalie Jäger, Daniel Haag, Mikołaj Słabicki, Stefan M. … , 03 April 2019. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 21(2019), 7, Seite 867-877
DOI: 10.1093/neuonc/noz057
- Johann, Pascal-David: RF_Purify : a novel tool for comprehensive analysis of tumor-purity in methylation array data based on random forest regression / Pascal David Johann, Natalie Jäger, Stefan M. Pfister and Martin Sill, 16 August 2019. - 9 S.
In: BMC bioinformatics, ISSN 1471-2105. 20(2019) Artikel-Nummer 428, 9 Seiten
DOI: 10.1186/s12859-019-3014-z
- Benesch, Martin: Newly diagnosed metastatic intracranial ependymoma in children : frequency, molecular characteristics, treatment, and outcome in the prospective HIT series / Martin Benesch, Martin Mynarek, Hendrik Witt, Monika Warmuth‐Metz, Torsten Pietsch, Brigitte Bison, … , March 8, 2019. - 9 S.
In: The oncologist, ISSN 1549-490X. 24(2019), 9, Seite e921-e929
DOI: 10.1634/theoncologist.2018-0489
- Korshunov, Andrey: Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles / Andrey Korshunov, Felix Sahm, Konstantin Okonechnikov, Marina Ryzhova, Damian Stichel, Daniel Schrim… , 2 March 2019. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 137(2019), 6, Seite 1003-1015
DOI: 10.1007/s00401-019-01981-6
- Pajtler, Kristian Wilfried: YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis / Kristian W. Pajtler, Yiju Wei, Konstantin Okonechnikov, Patricia B. G. Silva, Mikaella Vouri, Lei Zh… , 02 September 2019. - 16 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Artikel-Nummer 3914, 16 Seiten
DOI: 10.1038/s41467-019-11884-5
- Huang, Miller: Engineering genetic predisposition in human neuroepithelial stem cells recapitulates medulloblastoma tumorigenesis / Miller Huang, Jignesh Tailor, Qiqi Zhen, Aaron H. Gillmor, Matthew L. Miller, Holger Weishaupt, Just… , 13 June 2019. - 22 S.
In: Cell stem cell, ISSN 1875-9777. 25(2019), 3, Seite 433-446.e7
DOI: 10.1016/j.stem.2019.05.013
- Hovestadt, Volker: Resolving medulloblastoma cellular architecture by single-cell genomics / Volker Hovestadt, Kyle S. Smith, Laure Bihannic, Mariella G. Filbin, McKenzie L. Shaw, Alicia Baumga… , 24 July 2019. - 6 S.
In: Nature, ISSN 1476-4687. 572(2019), 7767, Seite 74-79
DOI: 10.1038/s41586-019-1434-6
- Korshunov, Andrey: Integrated molecular characterization of IDH-mutant glioblastomas / A. Korshunov, B. Casalini, L. Chavez, T. Hielscher, M. Sill, M. Ryzhova, T. Sharma, D. Schrimpf, D. … , 2019. - 11 S.
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 45(2019), 2, Seite 108-118
DOI: 10.1111/nan.12523
- Pagès, Mélanie: Diagnostics of pediatric supratentorial RELA ependymomas : integration of information from histopathology, genetics, DNA methylation and imaging / Mélanie Pagès; Kristian W. Pajtler; Stéphanie Puget; David Castel; Nathalie Boddaert; Arnault Tauziè… , 2019. - 11 S.
In: Brain pathology, ISSN 1750-3639. 29(2019), 3, Seite 325-335
DOI: 10.1111/bpa.12664
- Pfaff, Elke: Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine : the INFORM study experience / Elke Pfaff, Ahmed El Damaty, Gnana Prakash Balasubramanian, Mirjam Blattner-Johnson, Barbara C. Wors… , 22 April 2019. - 9 S.
In: European journal of cancer, ISSN 1879-0852. 114(2019), Seite 27-35
DOI: 10.1016/j.ejca.2019.03.019
- Bandopadhayay, Pratiti: Neuronal differentiation and cell-cycle programs mediate response to BET-bromodomain inhibition in MYC-driven medulloblastoma / Pratiti Bandopadhayay et al., 03 June 2019. - 16 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Article number: 2400, 16 Seiten
DOI: 10.1038/s41467-019-10307-9
- Feuerbach, Lars: TelomereHunter : in silico estimation of telomere content and composition from cancer genomes / Lars Feuerbach, Lina Sieverling, Katharina I. Deeg, Philip Ginsbach, Barbara Hutter, Ivo Buchhalter,… . -
Heidelberg: Universitätsbibliothek Heidelberg, 06 Aug. 2019. - 1 Online-Ressource (11 Seiten)
- Binder, Hans: DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development / H. Binder, E. Willscher, H. Loeffler-Wirth, L. Hopp, D.T.W. Jones, S.M. Pfister, M. Kreuz, D. Gramat… . -
London: BioMed Central, 09 Jul. 2019. - 1 Online-Ressource (18 Seiten)
- Jaunmuktane, Zane: Methylation array profiling of adult brain tumours : diagnostic outcomes in a large, single centre / Zane Jaunmuktane, David Capper, David T.W. Jones, Daniel Schrimpf, Martin Sill, Monika Dutt, Nirosha… , 20 February 2019. - 18 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 7(2019), Artikel-ID 24, Seite 1-18
DOI: 10.1186/s40478-019-0668-8
- Zhang, Huan: Translating genomic medicine to the clinic : challenges and opportunities / Huan Zhang, Lars Klareskog, Andreas Matussek, Stefan M. Pfister and Mikael Benson, 22 February 2019. - 3 S.
In: Genome medicine, ISSN 1756-994X. 11(2019) Artikel-Nummer 9, 3 Seiten
DOI: 10.1186/s13073-019-0622-1
- Binder, Hans: DNA methylation, transcriptome and genetic copy number signatures of diffuse cerebral WHO grade II/III gliomas resolve cancer heterogeneity and development / H. Binder, E. Willscher, H. Loeffler-Wirth, L. Hopp, D.T.W. Jones, S.M. Pfister, M. Kreuz, D. Gramat… , 25 April 2019. - 18 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 7(2019), Artikel-ID 59, Seite 1-18
DOI: 10.1186/s40478-019-0704-8
- Hou, Yanghao: Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA / Yanghao Hou, Jorge Pinheiro, Felix Sahm, David E. Reuss, Daniel Schrimpf, Damian Stichel, Belén Casa… , 13 February 2019. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 137(2019), 5, Seite 837-846
DOI: 10.1007/s00401-019-01969-2
- Feuerbach, Lars: TelomereHunter : in silico estimation of telomere content and composition from cancer genomes / Lars Feuerbach, Lina Sieverling, Katharina I. Deeg, Philip Ginsbach, Barbara Hutter, Ivo Buchhalter,… , 28 May 2019. - 11 S.
In: BMC bioinformatics, ISSN 1471-2105. 20(2019) Artikel-Nummer 272, 11 Seiten
DOI: 10.1186/s12859-019-2851-0
- Northcott, Paul A.: Medulloblastoma / Paul A. Northcott, Giles W. Robinson, Christian P. Kratz, Donald J. Mabbott, Scott L. Pomeroy, Steve… , 14 February 2019
In: Nature reviews, ISSN 2056-676X. 5(2019, 1) Artikel-Nummer 11, ? Seiten
DOI: 10.1038/s41572-019-0063-6
- Kölsche, Christian: DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma / Christian Koelsche, Mark Kriegsmann, Felix K. F. Kommoss, Damian Stichel, Katharina Kriegsmann, Chri… , 20 March 2019. - 9 S.
In: Journal of cancer research and clinical oncology, ISSN 1432-1335. 145(2019), 5, Seite 1273-1281
DOI: 10.1007/s00432-019-02895-2
- Thomas, Christian: Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1 / Christian Thomas, Friederike Knerlich-Lukoschus, Harald Reinhard, Pascal D. Johann, Dominik Sturm, F… , 03 April 2019. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 137(2019), 5, Seite 847-850
DOI: 10.1007/s00401-019-02001-3
- Lee, Julieann C.: Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1 / Julieann C. Lee, Javier E. Villanueva-Meyer, Sean P. Ferris, Emily A. Sloan, Jeffrey W. Hofmann, Eya… , 16 January 2019. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 137(2019), 3, Seite 521-525
DOI: 10.1007/s00401-019-01960-x
- Kölsche, Christian: Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype / Christian Koelsche, Damian Stichel, Klaus G. Griewank, Daniel Schrimpf, David E. Reuss, Melanie Bewe… , 14 February 2019. - 8 S.
In: Clinical Sarcoma Research, ISSN 2045-3329. 9(2019), Artikel-ID 2, Seite 1-8
DOI: 10.1186/s13569-019-0113-6
- Erkek, Serap: Comprehensive analysis of chromatin states in atypical teratoid/rhabdoid tumor identifies diverging roles for SWI/SNF and polycomb in gene regulation / Serap Erkek, Pascal D. Johann, Martina A. Finetti, Yiannis Drosos, Hsien-Chao Chou, Marc Zapatka, Do… , 2019. - 25 S.
In: Cancer cell, ISSN 1878-3686. 35(2019,1) Seite 95-110.e8, 16 Seiten
DOI: 10.1016/j.ccell.2018.11.014
- Lee, Catherine: Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma / Catherine Lee, Vasilisa A. Rudneva, Serap Erkek, Marc Zapatka, Lianne Q. Chau, Silvia K. Tacheva-Gri… , 18 January 2019. - 13 S.
In: Nature Communications, ISSN 2041-1723. 10(2019) Artikel-Nummer 332, 13 Seiten
DOI: 10.1038/s41467-018-08269-5
- Robson, Jonathan P.: Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells / Jonathan P. Robson, Marc Remke, Marcel Kool, Elaine Julian, Andrey Korshunov, Stefan M. Pfister, Geo… , January 18, 2019. - 25 S.
In: PLOS ONE, ISSN 1932-6203. 14(2019,1) Artikel-Nummer e0210665, 25 Seiten
DOI: 10.1371/journal.pone.0210665
- Okonechnikov, Konstantin: InTAD : chromosome conformation guided analysis of enhancer target genes / Konstantin Okonechnikov, Serap Erkek, Jan O. Korbel, Stefan M. Pfister and Lukas Chavez
In: BMC bioinformatics, ISSN 1471-2105. 20(2019) Artikel-Nummer 60, 7 Seiten
DOI: 10.1186/s12859-019-2655-2
- Buhl, Juliane: The senescence-associated secretory phenotype mediates oncogene-induced senescence in pediatric pilocytic astrocytoma / Juliane L. Buhl, Florian Selt, Thomas Hielscher, Romain Guiho, Jonas Ecker, Felix Sahm, Johannes Rid… , 15 March 2019. - 16 S.
In: Clinical cancer research, ISSN 1557-3265. 25(2019), 6, Seite 1851-1866
DOI: 10.1158/1078-0432.CCR-18-1965
- Archer, Tenley C.: Proteomics, post-translational modifications, and integrative analyses reveal molecular heterogeneity within medulloblastoma subgroups / Tenley C. Archer, Tobias Ehrenberger, Filip Mundt, Maxwell P. Gold, Karsten Krug, Clarence K. Mah, E… , September 10, 2018. - 23 S.
In: Cancer cell, ISSN 1878-3686. 34(2018), 3, Seite 396-410, e1-e8
DOI: 10.1016/j.ccell.2018.08.004
- Appay, Romain: Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549 - BRAF fusion detection in pilocytic astrocytomas / Romain Appay, Frédéric Fina, Nicolas Macagno, Laëtitia Padovani, Carole Colin, Doriane Barets, Joann… , 25 May 2018. - 12 S.
In: Modern pathology, ISSN 1530-0285. 31(2018), 10, Seite 1490-1501
DOI: 10.1038/s41379-018-0050-6
- Feng, Weijun: CRISPR-mediated loss of function analysis in cerebellar granule cells using in utero electroporation-based gene transfer / Weijun Feng, Lena Herbst, Peter Lichter, Stefan M. Pfister, Hai-Kun Liu, Daisuke Kawauchi, 6/09/2018. - 1 Online-Ressource (1 Videodatei, 2:00 min) : farbig
In: JoVE, ISSN 1940-087X. (2018), 136, Artikel-ID e57311, Seite ?
DOI: 10.3791/57311
- Akgül, Seçkin: Opposing tumor-promoting and -suppressive functions of Rictor/mTORC2 Signaling in adult glioma and pediatric SHH medulloblastoma / Seçkin Akgül, Yinghua Li, Siyuan Zheng, Marcel Kool, Daniel M. Treisman, Chaoyang Li, Yuan Wang, Sus… , July 10, 2018. - 21 S.
In: Cell reports, ISSN 2211-1247. 24(2018), 2, Seite 463-478, e1-e5
DOI: 10.1016/j.celrep.2018.06.050
- Gröbner, Susanne: Author correction: The landscape of genomic alterations across childhood cancers / Susanne N. Gröbner, Barbara C. Worst, Joachim Weischenfeldt, Ivo Buchhalter, Kortine Kleinheinz, Vas… , 06 June 2018. - 1 S.
In: Nature, ISSN 1476-4687. 559(2018), 7714, Seite E10-E10
DOI: 10.1038/s41586-018-0167-2
- Dudvarski-Stanković, Nevenka: EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors / Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne K… , 2018 Aug 2.. - 19 S.
In: EMBO molecular medicine, ISSN 1757-4684. 10(2018,9) Artikel-Nummer e8420, 19 Seiten
DOI: 10.15252/emmm.201708420
- Forget, Antoine: Aberrant ERBB4-SRC signaling as a hallmark of group 4 medulloblastoma revealed by integrative phosphoproteomic profiling / Antoine Forget, Loredana Martignetti, Stéphanie Puget, Laurence Calzone, Sebastian Brabetz, Daniel P… , September 10, 2018. - 24 S.
In: Cancer cell, ISSN 1878-3686. 34(2018,3) 379-395, e1-e7, 24 Seiten
DOI: 10.1016/j.ccell.2018.08.002
- Stichel, Damian: Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma / Damian Stichel, Azadeh Ebrahimi, David Reuss, Daniel Schrimpf, Takahiro Ono, Mitsuaki Shirahata, Gui… , 5 September 2018. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 5, Seite 793-803
DOI: 10.1007/s00401-018-1905-0
- Robinson, Giles W.: Risk-adapted therapy for young children with medulloblastoma (SJYC07) : therapeutic and molecular outcomes from a multicentre, phase 2 trial / Giles W Robinson, Vasilisa A Rudneva, Ivo Buchhalter, Catherine A Billups, Sebastian M Waszak, Kyle … , May 16, 2018. - 17 S.
In: The lancet, ISSN 1474-5488. 19(2018), 6, Seite 768-784
DOI: 10.1016/S1470-2045(18)30204-3
- Rivero-Hinojosa, Samuel: Proteomic analysis of Medulloblastoma reveals functional biology with translational potential / Samuel Rivero-Hinojosa, Ling San Lau, Mojca Stampar, Jerome Staal, Huizhen Zhang, Heather Gordish-Dr… , 07 June 2018. - 19 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 6(2018), Artikel-ID 48, Seite 1-19
DOI: 10.1186/s40478-018-0548-7
- Merk, Daniel J.: Opposing effects of CREBBP mutations govern the phenotype of Rubinstein-Taybi syndrome and adult SHH medulloblastoma / Daniel J. Merk, Jasmin Ohli, Natalie D. Merk, Venu Thatikonda, Sorana Morrissy, Melanie Schoof, Susa… , March 15, 2018. - 23 S.
In: Developmental cell, ISSN 1878-1551. 44(2018), 6, Seite 709-724, e1-e6
DOI: 10.1016/j.devcel.2018.02.012
- Witt, Hendrik: DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment / Hendrik Witt, Dorothee Gramatzki, Bettina Hentschel, Kristian W. Pajtler, Jörg Felsberg, Gabriele Sc… , 24 July 2018. - 9 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 12, Seite 1616-1624
DOI: 10.1093/neuonc/noy118
- Wirsching, Hans-Georg: Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma : the randomized, open-label, phase II ARTE trial / H.-G. Wirsching, G. Tabatabai, U. Roelcke, A.F. Hottinger, F. Jörger, A. Schmid, L. Plasswilm, D. Sc… , 6 January 2020. - 8 S.
In: Annals of oncology, ISSN 1569-8041. 29(2018), 6, Seite 1423-1430
DOI: 10.1093/annonc/mdy120
- Beier, Dagmar: Multicenter pilot study of radiochemotherapy as first-line treatment for adults with medulloblastoma (NOA-07) / Dagmar Beier, Martin Proescholdt, Christiane Reinert, Torsten Pietsch, David T W Jones, Stefan M Pfi… , 2018. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 3, Seite 400-410
DOI: 10.1093/neuonc/nox155
- Hoffman, Lindsey M.: Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG) : a collaborative report from the International and European Society for Pediatric Oncology DIPG Registries / Lindsey M. Hoffman, Sophie E.M. Veldhuijzen van Zanten, Niclas Colditz, Joshua Baugh, Brooklyn Chane… , May 10, 2018. - 10 S.
In: Journal of clinical oncology, ISSN 1527-7755. 36(2018), 19, Seite 1963-1972
DOI: 10.1200/JCO.2017.75.9308
- Pajtler, Kristian Wilfried: Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas / Kristian W. Pajtler, Ji Wen, Martin Sill, Tong Lin, Wilda Orisme, Bo Tang, Jens-Martin Hübner, Vijay… , 16 June 2018. - 16 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 211-226
DOI: 10.1007/s00401-018-1877-0
- SYS-GLIO: Systembasierte Vorhersagen für das biologische und klinische Verhalten von Gliomen : Abschlussbericht : Laufzeit des Vorhabens: 01.03.2015-28.02.2018 (verlängert bis 31.12.2018) : Berichtszeitraum: 01.03.2015-31.12.2018 / Zuwendungsempfänger: Prof. Dr. Peter Lichter, Leiter der Abteilung Molekulare Genetik, DKFZ; Prof. D… . -
Heidelberg: DKFZ, [2018?]. - 8 Blätter
- Bächli, Heidi: Molecular diagnostics in pediatric brain tumors : impact on diagnosis and clinical decision-making - a selected case series / Heidi Bächli, Jonas Ecker, Cornelis van Tilburg, Dominik Sturm, Florian Selt, Felix Sahm, Christian … , 11. Juli 2018. - 9 S.
In: Klinische Pädiatrie, ISSN 1439-3824. 230(2018), 06, Seite 305-313
DOI: 10.1055/a-0637-9653
- Tejada Neyra, Miguel Angel: Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma / Miguel Angel Tejada Neyra, Ulf Neuberger, Annekathrin Reinhardt, Gianluca Brugnara, David Bonekamp, … , 9 August 2018. - 8 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 11, Seite 1517-1524
DOI: 10.1093/neuonc/noy134
- Infante, Paola: Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis / Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Ro… , 07 March 2018. - 17 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 976, 17 Seiten
DOI: 10.1038/s41467-018-03339-0
- Deng, Maximilian: Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features / Maximilian Y. Deng, Martin Sill, Jason Chiang, Jens Schittenhelm, Martin Ebinger, Martin U. Schuhman… , 15 May 2018. - 15 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 239-253
DOI: 10.1007/s00401-018-1865-4
- Korshunov, Andrey: Molecular characterization of medulloblastomas with extensive nodularity (MBEN) / Andrey Korshunov, Felix Sahm, Damian Stichel, Daniel Schrimpf, Marina Ryzhova, Olga Zheludkova, Andr… , 22 March 2018. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 303-313
DOI: 10.1007/s00401-018-1840-0
- Reinhardt, Annekathrin: Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations / Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Felix Sahm, Andrey Korshunov, David E. Reuss… , 21 March 2018. - 19 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 273-291
DOI: 10.1007/s00401-018-1837-8
- Solomon, David A.: Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile / David A. Solomon, Andrey Korshunov, Martin Sill, David T. W. Jones, Marcel Kool, Stefan M. Pfister, … , 13 July 2018. - 5 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 339-343
DOI: 10.1007/s00401-018-1883-2
- Snuderl, Matija: Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma / Matija Snuderl, Kasthuri Kannan, Elke Pfaff, Shiyang Wang, James M. Stafford, Jonathan Serrano, Adri… , 20 July 2018. - 10 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 2868, 10 Seiten
DOI: 10.1038/s41467-018-05029-3
- Kölsche, Christian: Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations / Christian Koelsche, Martin Mynarek, Daniel Schrimpf, Luca Bertero, Jonathan Serrano, Felix Sahm, Dav… , 7 June 2018. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 327-337
DOI: 10.1007/s00401-018-1871-6
- Kölsche, Christian: Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information / Christian Koelsche, Wolfgang Hartmann, Daniel Schrimpf, Damian Stichel, Susanne Jabar, Andreas Ranft… , 23 March 2018. - 11 S.
In: Modern pathology, ISSN 1530-0285. 31(2018), 8, Seite 1246-1256
DOI: 10.1038/s41379-018-0045-3
- Johann, Pascal-David: Sellar region atypical teratoid/rhabdoid tumors (ATRT) in adults display DNA methylation profiles of the ATRT-MYC subgroup / Pascal D. Johann, MD, Susanne Bens, MD, Florian Oyen, Rabea Wagener, PhD, Caterina Giannini, MD, Ar… , April 2018. - 5 S.
In: The American journal of surgical pathology, ISSN 1532-0979. 42(2018), 4, Seite 506-511
DOI: 10.1097/PAS.0000000000001023
- Sievers, Philipp: FGFR1 : TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma / Philipp Sievers, Damian Stichel, Daniel Schrimpf, Felix Sahm, Christian Koelsche, David E. Reuss, An… , 5 July 2018. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 293-302
DOI: 10.1007/s00401-018-1882-3
- Sievers, Philipp: Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p / Philipp Sievers · Damian Stichel · Thomas Hielscher · Daniel Schrimpf · Annekathrin Reinhardt · Anni… , 31 October 2018. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 6, Seite 975-978
DOI: 10.1007/s00401-018-1924-x
- Shirahata, Mitsuaki: Novel, improved grading system(s) for IDH-mutant astrocytic gliomas / Mitsuaki Shirahata, Takahiro Ono, Damian Stichel, Daniel Schrimpf, David E. Reuss, Felix Sahm, Chris… , 2018. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 1, Seite 153-166
DOI: 10.1007/s00401-018-1849-4
- Mackay, Alan: Molecular, pathological, radiological, and immune profiling of non-brainstem pediatric high-grade glioma from the HERBY phase II randomized trial / Alan Mackay, Anna Burford, Valeria Molinari, David T. W. Jones, Elisa Izquierdo, Jurriaan Brouwer-Vi… , [14 May 2018]. - 19 S. : Illustrationen
In: Cancer cell, ISSN 1878-3686. 33(2018), 5, Seite 829-842.e1-35
DOI: 10.1016/j.ccell.2018.04.004
- Lichter, Peter: Projekttitel: Charakterisierung des nicht-Protein-kodierenden Subgenoms in Tumorzellen durch Mining genomweiter Omics-Datensätze aus den deutschen ICGC Projekten : Schlussbericht ICGC-DE-Mining / Zuwendungsempfänger: DKFZ ; Autoren: Lichter, Peter; Pfister, Stefan; Brors, Benedikt; Plass, Christ… . -
[Heidelberg]: DKFZ, [2018?]. - 1 Online-Ressource (12 Seiten, 184,42 KB)
DOI: 10.2314/GBV:1662853432
- Lichter, Peter: Projekttitel: Charakterisierung des nicht-Protein-kodierenden Subgenoms in Tumorzellen durch Mining genomweiter Omics-Datensätze aus den deutschen ICGC Projekten : Schlussbericht ICGC-DE-Mining / Zuwendungsempfänger: DKFZ ; Autoren: Lichter, Peter; Pfister, Stefan; Brors, Benedikt; Plass, Christ… . -
[Heidelberg]: DKFZ, [2018?]. - 10 Blätter, 2 ungezählte Blätter
- Brabetz, Sebastian: A biobank of patient-derived pediatric brain tumor models / Sebastian Brabetz, Sarah E. S. Leary, Susanne N. Gröbner, Madison W. Nakamoto, Huriye Şeker-Cin, Emi… , 22 October 2018. - 10 S.
In: Nature medicine, ISSN 1546-170X. 24(2018), 11, Seite 1752-1761
DOI: 10.1038/s41591-018-0207-3
- Korshunov, Andrey: DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas / Andrey Korshunov, Felix Sahm, Olga Zheludkova, Andrey Golanov, Damian Stichel, Daniel Schrimpf, Mari… , 2019. - 8 S.
In: Neuro-Oncology, ISSN 1523-5866. 21(2019), 2, Seite 214-221
DOI: 10.1093/neuonc/noy155
- Wegert, Jenny: Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants / Jenny Wegert, Christian Vokuhl, Grace Collord, Martin Del Castillo Velasco-Herrera, Sarah J. Farndon… , 18 June 2018. - 6 S.
In: Nature Communications, ISSN 2041-1723. 9(2018), Artikel-ID 2378, Seite 1-6
DOI: 10.1038/s41467-018-04650-6
- Wick, Wolfgang: N2M2 (NOA-20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma / Wolfgang Wick, Susan Dettmer, Anne Berberich, Tobias Kessler, Irini Karapanagiotou-Schenkel, Antje W… , [January 2019]. - 11 S. : Illustrationen
In: Neuro-Oncology, ISSN 1523-5866. 21(2019), 1, Seite 95-105
DOI: 10.1093/neuonc/noy161
- Gómez, Soledad: A novel method for rapid molecular subgrouping of medulloblastoma / Soledad Gómez, Alícia Garrido-Garcia, Laura Garcia-Gerique, Isadora Lemos, Mariona Suñol, Carmen de … , March 2018. - 9 S.
In: Clinical cancer research, ISSN 1557-3265. 24(2018), 6, Seite 1355-1363
DOI: 10.1158/1078-0432.CCR-17-2243
- Ratnaparkhe, Manasi: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors / Manasi Ratnaparkhe, John K. L. Wong, Pei-Chi Wei, Mario Hlevnjak, Thorsten Kolb, Milena Simovic, Dan… , 2018. - 13 S.
In: Nature Communications, ISSN 2041-1723. 9(2018) Artikel-Nummer 4760, 13 Seiten
DOI: 10.1038/s41467-018-06925-4
- Rutkowski, Stefan: Biological material collection to advance translational research and treatment of children with CNS tumours : position paper from the SIOPE Brain Tumour Group / Stefan Rutkowski, Piergiorgio Modena, Daniel Williamson, Kornelius Kerl, Karsten Nysom, Barry Pizer,… , 1 August 2018. - 10 S.
In: The lancet, ISSN 1474-5488. 19(2018), 8, Seite e419-e428
DOI: 10.1016/S1470-2045(18)30364-4
- Cavalli, Florence M. G.: Heterogeneity within the PF-EPN-B ependymoma subgroup / Florence M.G. Cavalli, Jens-Martin Hübner, Tanvi Sharma, Betty Luu, Martin Sill, Michal Zapotocky, S… , [August 2018]. - 11 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 227-237
DOI: 10.1007/s00401-018-1888-x
- Castel, David: Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location / David Castel, Cathy Philippe, Thomas Kergrohen, Martin Sill, Jane Merlevede, Emilie Barret, Stéphani… , 5 November 2018. - 13 S. : Illustrationen
In: Acta Neuropathologica Communications, ISSN 2051-5960. 6(2018), Artikel-ID 117, Seite 1-13
DOI: 10.1186/s40478-018-0614-1
- Capper, David: Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics : the Heidelberg experience / David Capper, Damian Stichel, Felix Sahm, David T. W. Jones, Daniel Schrimpf, Martin Sill, Simone Sc… , August 2018. - 40 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 181-210
DOI: 10.1007/s00401-018-1879-y
- Capper, David: DNA methylation-based reclassification of olfactory neuroblastoma / David Capper, Nils W. Engel, Damian Stichel, Matt Lechner, Stefanie Glöss, Simone Schmid, Christian … , August 2018. - 17 S. : Illustrationen
In: Acta neuropathologica, ISSN 1432-0533. 136(2018), 2, Seite 255-271
DOI: 10.1007/s00401-018-1854-7
- Hwang, Eugene: Extensive molecular and clinical heterogeneity in patients with histologically diagnosed cns-pnet treated as a single entity : a report from the children’s oncology group randomized ACNS0332 trial / Eugene I. Hwang, Marcel Kool, Peter C. Burger, David Capper, Lukas Chavez, Sebastian Brabetz, Chris … , December 1, 2018. - 8 S.
In: Journal of clinical oncology, ISSN 1527-7755. 36(2018), 34, Seite 3388-3395
DOI: 10.1200/JCO.2017.76.4720
- Hübner, Jens-Martin: Epidemiology, molecular classification and WHO grading of ependymoma / Jens-Martin Hübner, Marcel Kool, Stefan M. Pfister, Kristian W. Pajtler, 2018. - 5 S.
In: The journal of neurosurgical sciences, ISSN 1827-1855. 62(2017), 1, Seite 46-50
DOI: 10.23736/S0390-5616.17.04152-2
- Korshunov, Andrey: Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis / Andrey Korshunov, Lukas Chavez, Tanvi Sharma, Marina Ryzhova, Daniel Schrimpf, Damian Stichel, David… , 2018. - 7 S.
In: Brain pathology, ISSN 1750-3639. 28(2018), 5, Seite 656-662
DOI: 10.1111/bpa.12566
- Vollmuth, Philipp: Radiomic subtyping improves disease stratification beyond key molecular, clinical, and standard imaging characteristics in patients with glioblastoma / Philipp Kickingereder, Ulf Neuberger, David Bonekamp, Paula L. Piechotta, Michael Götz, Antje Wick, … , 2018. - 10 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 6, Seite 848-857
DOI: 10.1093/neuonc/nox188
- Waszak, Sebastian Martin: Spectrum and prevalence of genetic predisposition in medulloblastoma : a retrospective genetic study and prospective validation in a clinical trial cohort / Sebastian M. Waszak, Paul A. Northcott, Ivo Buchhalter, Giles W. Robinson, Christian Sutter, Susanne… , 2018. - 14 S.
In: The lancet, ISSN 1474-5488. 19(2018), 6, Seite 785-798
DOI: 10.1016/S1470-2045(18)30242-0
- Capper, David: DNA methylation-based classification of central nervous system tumours / David Capper, David T.W. Jones, Martin Sill, Volker Hovestadt, Daniel Schrimpf, Dominik Sturm, Chris… , 14 March 2018. - 6 S.
In: Nature, ISSN 1476-4687. 555(2018), 7697, Seite 469-474
DOI: 10.1038/nature26000
- Gröbner, Susanne: The landscape of genomic alterations across childhood cancers, 28.02.2018. - 7 S.
In: Nature, ISSN 1476-4687. 555(2018), Seite 321-327
DOI: 10.1038/nature25480
- Rippe, Karsten: Schlussbericht zum e:Med - Modul I - Verbundprojekt "CancerTelSys - Identifizierung von Netzwerken für die Telomererhaltung in Tumoren zur Diagnose, Prognose, Patientenstratifizierung und Vorhersage der Therapieantwort" : Laufzeit des Vorhabens: 1.3.2014-28.2.2017 / Zuwendungsempfänger: Deutsches Krebsforschungszentrum DKFZ, Heidelberg; Universitätsklinikum Jena; U… . -
[Heidelberg]: [Deutsches Krebsforschungszentrum DKFZ], [2017?]. - 1 Online-Ressource (39 Seiten, 351 KB)
DOI: 10.2314/GBV:1017756007
- Rippe, Karsten: Schlussbericht zum e:Med - Modul I - Verbundprojekt "CancerTelSys - Identifizierung von Netzwerken für die Telomererhaltung in Tumoren zur Diagnose, Prognose, Patientenstratifizierung und Vorhersage der Therapieantwort" : Laufzeit des Vorhabens: 1.3.2014-28.2.2017 / Zuwendungsempfänger: Deutsches Krebsforschungszentrum DKFZ, Heidelberg; Universitätsklinikum Jena; U… . -
[Heidelberg]: [Deutsches Krebsforschungszentrum DKFZ], [2017?]. - 38 Blätter, 1 ungezähltes Blatt
- Keßler, Tobias: Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation / Tobias Kessler, Felix Sahm, Ahmed Sadik, Damian Stichel, Anne Hertenstein, Guido Reifenberger, Angel… , 2018. - 13 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 3, Seite 367-379
DOI: 10.1093/neuonc/nox160
- Johann, Pascal-David: Cribriform neuroepithelial tumor : molecular characterization of a SMARCB1-deficient non-rhabdoid tumor with favorable long-term outcome / Pascal D. Johann, Volker Hovestadt, Christian Thomas, Astrid Jeibmann, Katharina Heß, Susanne Bens, … , 05 June 2017. - 8 S.
In: Brain pathology, ISSN 1750-3639. 27(2017), 4, Seite 411-418
DOI: 10.1111/bpa.12413
- Kratz, Christian Peter: Cancer screening recommendations for individuals with Li-Fraumeni syndrome / Christian P. Kratz, Maria Isabel Achatz, Laurence Brugières, Thierry Frebourg, Judy E. Garber, Mary-… , June 2017. - 8 S.
In: Clinical cancer research, ISSN 1557-3265. 23(2017), 11, Seite e38-e45
DOI: 10.1158/1078-0432.CCR-17-0408
- Korshunov, Andrey: H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers / Andrey Korshunov, Daniel Schrimpf, Marina Ryzhova, Dominik Sturm, Lukas Chavez, Volker Hovestadt, Ta… , 11 April 2017. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 134(2017), 3, Seite 507-516
DOI: 10.1007/s00401-017-1710-1
- Korshunov, Andrey: DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma / Andrey Korshunov, Lukas Chavez, Paul A. Northcott, Tanvi Sharma, Marina Ryzhova, David T. W. Jones, … , 13 October 2017. - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 134(2017), 6, Seite 965-967
DOI: 10.1007/s00401-017-1776-9
- Liu, Kun-Wei: Molecular mechanisms and therapeutic targets in pediatric brain tumors / Kun-Wei Liu, Kristian W. Pajtler, Barbara C. Worst, Stefan M. Pfister, Robert J. Wechsler-Reya, 14 March 2017. - 20 S.
In: Science signaling, ISSN 1937-9145. 10(2017), 470, Artikel-ID eaaf7593
DOI: 10.1126/scisignal.aaf7593
- Margolin‐Miller, Yulia: Prognostic relevance of miR-124-3p and its target TP53INP1 in pediatric ependymoma / Yulia Margolin‐Miller, Natalia Yanichkin, Keren Shichrur, Helen Toledano, Anat Ohali, Theophilos Tza… . - 12 S.
In: Genes, chromosomes & cancer, ISSN 1098-2264. 56(2017), 8, S. 639-650
DOI: 10.1002/gcc.22467
- Bartenhagen, Christoph: Infection as a cause of childhood leukemia : virus detection employing whole genome sequencing / Christoph Bartenhagen, Ute Fischer, Klaus Korn, Stefan M. Pfister, Michael Gombert, Cai Chen, Vera O… , 2017-05-01. - 5 S.
In: Haematologica, ISSN 1592-8721. 102(2017), 5, Seite e179-e183
DOI: 10.3324/haematol.2016.155382
- Tilburg, Cornelis M. van: Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib / Cornelis M. van Tilburg, Florian Selt, Felix Sahm, Heidi Bächli, Stefan M. Pfister, Olaf Witt, Till … , 2018. - 4 S.
In: Pediatric blood & cancer, ISSN 1545-5017. 65(2018), 3, Artikel-ID e26893, Seite 1-4
DOI: 10.1002/pbc.26893
- Meehan, Terrence F.: PDX-MI : Minimal Information for Patient-Derived Tumor Xenograft Models / Terrence F. Meehan, Nathalie Conte, Theodore Goldstein, Giorgio Inghirami, Mark A. Murakami, Sebasti… , October 31, 2017. - 5 S.
In: Cancer research, ISSN 1538-7445. 77(2017), 21, Seite e62-e66
DOI: 10.1158/0008-5472.CAN-17-0582
- Gojo, Johannes: Telomerase activation in posterior fossa group a ependymomas is associated with dismal prognosis and chromosome 1q gain / Johannes Gojo, Daniela Lötsch, Sabine Spiegl-Kreinecker, Kristian W. Pajtler, Katharina Neumayer, Pi… , 24 March 2017. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 19(2017), 9, Seite 1183-1194
DOI: 10.1093/neuonc/nox027
- Villani, Anita: Recommendations for cancer surveillance in individuals with RASopathies and other rare genetic conditions with increased cancer risk / Anita Villani, Mary-Louise C. Greer, Jennifer M. Kalish, Akira Nakagawara, Katherine L. Nathanson, K… , June 14, 2017. - 8 S.
In: Clinical cancer research, ISSN 1557-3265. 23(2017), 12, Seite e83-e90
DOI: 10.1158/1078-0432.CCR-17-0631
- Feng, Weijun: Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme / Weijun Feng, Daisuke Kawauchi, Huiqin Körkel-Qu, Huan Deng, Elisabeth Serger, Laura Sieber, Jenna Ar… , 20 Mar 2017. - 14 S.
In: Nature Communications, ISSN 2041-1723. 8(2017) Artikel-Nummer 14758, 14 Seiten
DOI: 10.1038/ncomms14758
- Majewsky, Marius: Systematic identification of suspected anthelmintic benzimidazole metabolites using LC-MS/MS / Marius Majewsky, David Castel, Ludivine Le Dret, Pascal Johann, David T. Jones, Stefan M. Pfister, W… , 2018. - 8 S.
In: Journal of pharmaceutical and biomedical analysis, ISSN 1873-264X. 151(2018), Seite 151-158
DOI: 10.1016/j.jpba.2017.12.056
- Pfaff, Elke: Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation : the NCT Neuro Master Match (N2M2) pilot study / Elke Pfaff, Tobias Kessler, Gnana Prakash Balasubramanian, Anne Berberich, Daniel Schrimpf, Antje Wi… , 2018. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 6, Seite 826-837
DOI: 10.1093/neuonc/nox216
- Jones, David T. W.: BRAF V600E status alone is not sufficient as a prognostic biomarker in pediatric low-grade glioma / David T.W. Jones, Olaf Witt and Stefan M. Pfister, Uri Tabori, Eric Bouffet, and Cynthia E. Hawkins, 2018. - 1 S.
In: Journal of clinical oncology, ISSN 1527-7755. 36(2018), 1, Seite 96
DOI: 10.1200/JCO.2017.75.8987
- Jeibmann, Astrid: SMAD dependent signaling plays a detrimental role in a fly model of SMARCB1-deficiency and the biology of atypical teratoid/rhabdoid tumors / Astrid Jeibmann, Jacqueline Schulz, Kristin Eikmeier, Pascal D. Johann, Katharina Thiel, Isabel Tege… , 20 January 2017. - 8 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 131(2017), 3, Seite 477-484
DOI: 10.1007/s11060-016-2326-3
- Kawauchi, Daisuke: Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells / D. Kawauchi, R.J. Ogg, L. Liu, D.J.H. Shih, D. Finkelstein, B.L. Murphy, J E. Rehg, A. Korshunov, C.… , 15 May 2017. - 12 S.
In: Oncogene, ISSN 1476-5594. 36(2017), 37, Seite 5231-5242
DOI: 10.1038/onc.2017.110
- Mackay, Alan: Integrated molecular meta-analysis of 1,000 pediatric high-grade and diffuse intrinsic pontine glioma / Alan Mackay, Anna Burford, Diana Carvalho, Elisa Izquierdo, Janat Fazal-Salom, Kathryn R. Taylor, Ly… , 9 October 2017. - 18 S.
In: Cancer cell, ISSN 1878-3686. 32(2017), 4, Seite 520-537
DOI: 10.1016/j.ccell.2017.08.017
- Mack, Stephen C.: Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling / Stephen C. Mack, Kristian W. Pajtler, Lukas Chavez, Konstantin Okonechnikov, Kelsey C. Bertrand, Xiu… , 2018. - 5 S.
In: Nature, ISSN 1476-4687. 553(2018), 7686, Seite 101-105
DOI: 10.1038/nature25169
- Selt, Florian: Establishment and application of a novel patient-derived KIAA1549 : BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing / Florian Selt, Juliane Hohloch, Thomas Hielscher, Felix Sahm, David Capper, Andrey Korshunov, Diren U… , 2017. - 20 S.
In: OncoTarget, ISSN 1949-2553. 8(2017), 7, Seite 11460-11479
DOI: 10.18632/oncotarget.14004
- Pearson, Andrew D. J.: From class waivers to precision medicine in paediatric oncology / Andrew D.J. Pearson, Stefan M. Pfister, Andre Baruchel, Jean-Pierre Bourquin, Michela Casanova, Loui… , 28 June 2017. - 11 S.
In: The lancet, ISSN 1474-5488. 18(2017), 7, Seite e394-e404
DOI: 10.1016/S1470-2045(17)30442-4
- Ripperger, Tim: Childhood cancer predisposition syndromes : a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology / Tim Ripperger, Stefan S. Bielack, Arndt Borkhardt, Ines B. Brecht, Birgit Burkhardt, Gabriele Calami… , 2017. - 21 S.
In: American journal of medical genetics, ISSN 1552-4833. 173(2017), 4, Seite 1017-1037
DOI: 10.1002/ajmg.a.38142
- Sahm, Felix: Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature / Felix Sahm, Umut H. Toprak, Daniel Hübschmann, Kortine Kleinheinz, Ivo Buchhalter, Martin Sill, Dami… , 2017. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 134(2017), 1, Seite 155-158
DOI: 10.1007/s00401-017-1715-9
- Sahm, Felix: Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas / Felix Sahm, Andrey Korshunov, Daniel Schrimpf, Damian Stichel, David T. W. Jones, David Capper, Chri… , 2017. - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 133(2017), 2, Seite 325-327
DOI: 10.1007/s00401-016-1657-7
- Sturm, Dominik: Pediatric gliomas : current concepts on diagnosis, biology, and clinical management / Dominik Sturm, Stefan M. Pfister, and David T.W. Jones, 2017. - 9 S.
In: Journal of clinical oncology, ISSN 1527-7755. 35(2017), 21, Seite 2370-2377
DOI: 10.1200/JCO.2017.73.0242
- Panwalkar, Pooja: Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome / Pooja Panwalkar, Jonathan Clark, Vijay Ramaswamy, Debra Hawes, Fusheng Yang, Christopher Dunham, Ste… , 21 July 2017. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 134(2017), 5, Seite 705-714
DOI: 10.1007/s00401-017-1752-4
- Andreiuolo, Felipe: Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication : a new model for risk stratification / Felipe Andreiuolo, Gwénaël Le Teuff, Mohamed Amine Bayar, John-Paul Kilday, Torsten Pietsch, André O… , June 15, 2017. - 17 S.
In: PLOS ONE, ISSN 1932-6203. 12(2017,6) Artikel-Nummer e0178351, 17 Seiten
DOI: 10.1371/journal.pone.0178351
- Pajtler, Kristian Wilfried: The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants / Kristian W. Pajtler, Stephen C. Mack, Vijay Ramaswamy, Christian A. Smith, Hendrik Witt, Amy Smith, … , 17 November 2016. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 133(2017), 1, Seite 5-12
DOI: 10.1007/s00401-016-1643-0
- Schmidt, Christin: Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients / Christin Schmidt, Nil A. Schubert, Sebastian Brabetz, Norman Mack, Benjamin Schwalm, Jennifer A. Cha… , 08 May 2017. - 11 S.
In: Neuro-Oncology, ISSN 1523-5866. 19(2017), 12, Seite 1607-1617
DOI: 10.1093/neuonc/nox093
- Morrissy, A. Sorana: Spatial heterogeneity in medulloblastoma / A. Sorana Morrissy, Florence M. G. Cavalli, Marc Remke, Vijay Ramaswamy, David J. H. Shih, Borja L. … , 10 April 2017. - 9 S.
In: Nature genetics, ISSN 1546-1718. 49(2017), 5, Seite 780-788
DOI: 10.1038/ng.3838
- Schlagmann, Maria: The ß-catenin/CBP-antagonist ICG-001 inhibits pediatric glioma tumorigenicity in a Wnt-independent manner / Maria Wiese, Neele Walther, Christopher Diederichs, Fabian Schill, Sebastian Monecke, Gabriela Salin… . - 14 S.
In: OncoTarget, ISSN 1949-2553. 8(2017), 16, S. 27300-27313
DOI: 10.18632/oncotarget.15934
- Moreno, Lucas: Early phase clinical trials of anticancer agents in children and adolescents : an ITCC perspective / Lucas Moreno, Andrew D. J. Pearson, Xavier Paoletti, Irene Jimenez, Birgit Geoerger, Pamela R. Kearn… , 16 May 2017. - 11 S.
In: Nature reviews, ISSN 1759-4782. 14(2017), 8, Seite 497-507
DOI: 10.1038/nrclinonc.2017.59
- Packer, Roger J.: Pediatric low-grade gliomas : implications of the biologic era / Roger J. Packer, Stephan Pfister, Olaf Witt. - 12 S.
In: Neuro-Oncology, ISSN 1523-5866. 19(2017), 6, S. 750-761
DOI: 10.1093/neuonc/now209
- Rudà, Roberta: EANO guidelines for the diagnosis and treatment of ependymal tumors / Roberta Rudà, Guido Reifenberger, Didier Frappaz, Stefan M. Pfister, Anne Laprie, Thomas Santarius, …
In: Neuro-Oncology, ISSN 1523-5866. 20(2018), 4, S. 445-456
DOI: 10.1093/neuonc/nox166
- Louis, David N.: cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy) : a new initiative in advancing nervous system tumor classification / David N. Louis, Ken Aldape,Daniel J. Brat, David Capper, David W. Ellison, Cynthia Hawkins, Werner P… , 2017. - 2 S.
In: Brain pathology, ISSN 1750-3639. 27(2017), 6, Seite 851-852
DOI: 10.1111/bpa.12457
- Louis, David N.: Announcing cIMPACT-NOW : the Consortium to inform molecular and practical approaches to CNS tumor taxonomy / David N. Louis, Ken Aldape, Daniel J. Brat, David Capper, David W. Ellison, Cynthia Hawkins, Werner … , 2017. - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 133(2017), 1, Seite 1-3
DOI: 10.1007/s00401-016-1646-x
- Olar, Adriana: Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma / Adriana Olar, Khalida M. Wani, Charmaine D. Wilson, Gelareh Zadeh, Franco DeMonte, David T.W. Jones,… , 27 January 2017. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 133(2017), 3, Seite 431-444
DOI: 10.1007/s00401-017-1678-x
- Ratnaparkhe, Manasi: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis / M. Ratnaparkhe, M. Hlevnjak, T. Kolb, A. Jauch, K.K. Maass, F. Devens, A. Rode, V. Hovestadt, A. Kor… , 14 March 2017. - 9 S.
In: Leukemia, ISSN 1476-5551. 31(2017), 10, Seite 2048-2056
DOI: 10.1038/leu.2017.55
- Kölsche, Christian: Histone 3.3 hotspot mutations in conventional osteosarcomas : a comprehensive clinical and molecular characterization of six H3F3A mutated cases / Christian Koelsche, Daniel Schrimpf, Lars Tharun, Eva Roth, Dominik Sturm, David T. W. Jones, Eva‑Kr… , 4 May 2017. - 11 S.
In: Clinical Sarcoma Research, ISSN 2045-3329. 7(2017), Artikel-ID 9, Seite 1-11
DOI: 10.1186/s13569-017-0075-5
- Kölsche, Christian: Histone 3.3 hotspot mutations in conventional osteosarcomas : a comprehensive clinical and molecular characterization of six H3F3A mutated cases / Christian Koelsche, Daniel Schrimpf, Lars Tharun, Eva Roth, Dominik Sturm, David T. W. Jones, Eva‑Kr… . -
London: BioMed Central, 04 May 2017. - 1 Online-Ressource (11 Seiten)
DOI: 10.1186/s13569-017-0075-5
- Sahm, Felix: DNA methylation-based classification and grading system for meningioma : a multicentre, retrospective analysis / Felix Sahm, Daniel Schrimpf, Damian Stichel, David TW Jones, Thomas Hielscher, Sebastian Schefzyk, K… , March 14, 2017. - 13 S.
In: The lancet, ISSN 1474-5488. 18(2017), 5, Seite 682-694
DOI: 10.1016/S1470-2045(17)30155-9
- Morrissy, A. Sorana: Divergent clonal selection dominates medulloblastoma at recurrence / A. Sorana Morrissy, Livia Garzia, David J.H. Shih, Scott Zuyderduyn, Xi Huang, Patryk Skowron, Marc … , 13 January 2016. - 7 S.
In: Nature, ISSN 1476-4687. 529(2016), 7586, Seite 351-357
DOI: 10.1038/nature16478
- Aldape, Kenneth: Next-generation molecular diagnostics / Kenneth Aldape, Stefan M. Pfister, 3 March 2016. - 10 S.
In: Gliomas. (2016), Seite 121-130
DOI: 10.1016/B978-0-12-802997-8.00007-4
- Mascelli, Samantha: TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma / Samantha Mascelli, Paolo Nozza, David T.W. Jones, Carole Colin, Angela Pistorio, Claudia Milanaccio,… , June 25, 2016. - 9 S.
In: OncoTarget, ISSN 1949-2553. 7(2016), 30, Seite 47918-47926
DOI: 10.18632/oncotarget.10295
- Ernst, Aurélie: Telomere dysfunction and chromothripsis / Aurélie Ernst, David T.W. Jones, Kendra K. Maass, Agata Rode, Katharina I. Deeg, Billy Michael Chell… , 9 Feb 2016. - 10 S.
In: International journal of cancer, ISSN 1097-0215. 138(2016), 12, Seite 2905-2914
DOI: 10.1002/ijc.30033
- Johann, Pascal-David: Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes / Pascal D. Johann, Serap Erkek, Marc Zapatka, Kornelius Kerl, Ivo Buchhalter, Volker Hovestadt, David… , February 25, 2016. - 15 S.
In: Cancer cell, ISSN 1878-3686. 29(2016), 3, Seite 379-393
DOI: 10.1016/j.ccell.2016.02.001
- Thompson, Eric M.: Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup : a retrospective integrated clinical and molecular analysis / Eric M Thompson, Thomas Hielscher, Eric Bouffet, Marc Remke, Betty Luu, Sridharan Gururangan, Roger … , March 11, 2016. - 12 S.
In: The lancet, ISSN 1474-5488. 17(2016), 4, Seite 484-495
DOI: 10.1016/S1470-2045(15)00581-1
- Lin, Charles Y.: Active medulloblastoma enhancers reveal subgroup-specific cellular origins / Charles Y. Lin, Serap Erkek, Yiai Tong, Linlin Yin, Alexander J. Federation, Marc Zapatka, Parthiv H… , 27 January 2016. - 6 S.
In: Nature, ISSN 1476-4687. 530(2016), 7588, Seite 57-62
DOI: 10.1038/nature16546
- Hölsken, Annett: Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles / Annett Hölsken, Martin Sill, Jessica Merkle, Leonille Schweizer, Michael Buchfelder, Jörg Flitsch, R… , 29 February 2016. - 13 S.
In: Acta Neuropathologica Communications, ISSN 2051-5960. 4(2016), Artikel-ID 20, Seite 1-13
DOI: 10.1186/s40478-016-0287-6
- Sahm, Felix: Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas / Felix Sahm, Frederick A. Jakobiec, Jochen Meyer, Daniel Schrimpf, Charles G. Eberhart, Volker Hovest… , 4 February 2016. - 10 S.
In: Genes, chromosomes & cancer, ISSN 1098-2264. 55(2016), 5, Seite 418-427
DOI: 10.1002/gcc.22344
- Sturm, Dominik: New brain tumor entities emerge from molecular classification of CNS-PNETs / Dominik Sturm, Brent A. Orr, Umut H. Toprak, Volker Hovestadt, David T.W. Jones, David Capper, Marti… , February 25, 2016. - 13 S.
In: Cell, ISSN 1097-4172. 164(2016), 5, Seite 1060-1072
DOI: 10.1016/j.cell.2016.01.015
- Hutter, Sonja: No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients / Sonja Hutter, Rosario M. Piro, Sebastian M. Waszak, Hildegard Kehrer-Sawatzki, Reinhard E. Friedrich… , 11 March 2016. - 7 S.
In: Human genetics, ISSN 1432-1203. 135(2016), 5, Seite 469-475
DOI: 10.1007/s00439-016-1646-x
- Thomas, Christian: Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups / Christian Thomas, Martin Sill, Vincent Ruland, Anika Witten, Stefan Hartung, Uwe Kordes, Astrid Jeib… , 28 January 2016. - 7 S.
In: Neuro-Oncology, ISSN 1523-5866. 18(2016), 6, Seite 790-796
DOI: 10.1093/neuonc/nov322
- Ramaswamy, Vijay: Risk stratification of childhood medulloblastoma in the molecular era : the current consensus / Vijay Ramaswamy, Marc Remke, Eric Bouffet, Simon Bailey, Steven C. Clifford, Francois Doz, Marcel Ko… , 4 April 2016. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 131(2016), 6, Seite 821-831
DOI: 10.1007/s00401-016-1569-6
- Röhrich, Manuel: Methylation-based classification of benign and malignant peripheral nerve sheath tumors / Manuel Röhrich, Christian Koelsche, Daniel Schrimpf, David Capper, Felix Sahm, Annekathrin Kratz, Ja… , 8 February 2016. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 131(2016), 6, Seite 877-887
DOI: 10.1007/s00401-016-1540-6
- Vijaya Ramaswamy: Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era : a retrospective multicohort analysis / Vijay Ramaswamy, Thomas Hielscher, Stephen C. Mack, Alvaro Lassaletta, Tong Lin, Kristian W. Pajtler… . - 10 S.
In: Journal of clinical oncology, ISSN 1527-7755. 34(2016), 21, S. 2468-2477
DOI: 10.1200/JCO.2015.65.7825
- Carceller, Fernando: Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma / Fernando Carceller, Lucy A. Fowkes, Komel Khabra, Lucas Moreno, Frank Saran, Anna Burford, Alan Mack… , August 2016. - 23 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 129(2016), 1, Seite 109-121
DOI: 10.1007/s11060-016-2151-8
- Jones, Chris: Pediatric high-grade glioma : biologically and clinically in need of new thinking / Chris Jones, Matthias A. Karajannis, David T. W. Jones, Mark W. Kieran, Michelle Monje, Suzanne J. B… , 2017. - 9 S.
In: Neuro-Oncology, ISSN 1523-5866. 19(2017), 2, Seite 153-161
DOI: 10.1093/neuonc/now101
- Hasselblatt, Martin: Poorly differentiated chordoma with SMARCB1/INI1 loss : a distinct molecular entity with dismal prognosis / Martin Hasselblatt, Christian Thomas, Volker Hovestadt, Daniel Schrimpf, Pascal Johann, Susanne Bens… . - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 132(2016), 1, S. 149-151
DOI: 10.1007/s00401-016-1574-9
- Jones, Barbara Christine: Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study / Barbara C. Worst, Cornelis M. van Tilburg, Gnana Prakash Balasubramanian, Petra Fiesel, Ruth Witt, A… , 29 July 2016. - 11 S.
In: European journal of cancer, ISSN 1879-0852. 65(2016), Seite 91-101
DOI: 10.1016/j.ejca.2016.06.009
- Selt, Florian: Pediatric targeted therapy : clinical feasibility of personalized diagnostics in children with relapsed and progressive tumors / Florian Selt, Alica Deiß, Andrey Korshunov, David Capper, Hendrik Witt, Cornelis M. van Tilburg, Dav… , 7 October 2015. - 11 S.
In: Brain pathology, ISSN 1750-3639. 26(2016), 4, Seite 506-516
DOI: 10.1111/bpa.12326
- Li, Peng: Nestin mediates hedgehog pathway tumorigenesis / Peng Li, Eric H. Lee, Fang Du, Renata E. Gordon, Larra W. Yuelling, Yongqiang Liu, Jessica M.Y. Ng, … . - 11 S.
In: Cancer research, ISSN 1538-7445. 76(2016), 18, S. 5573-5583
DOI: 10.1158/0008-5472.CAN-16-1547
- Henrich, Kai-Oliver: Integrative genome-scale analysis identifies epigenetic mechanisms of transcriptional deregulation in unfavorable neuroblastomas / Kai-Oliver Henrich, Sebastian Bender, Maral Saadati, Daniel Dreidax, Moritz Gartlgruber, Chunxuan Sh… , 7 September 2016. - 15 S.
In: Cancer research, ISSN 1538-7445. 76(2016), 18, Seite 5523-5537
DOI: 10.1158/0008-5472.CAN-15-2507
- Tzaridis, Theophilos-Dimitrios: Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA -positive ependymoma / Theophilos Tzaridis, Till Milde, Kristian W. Pajtler, Sebastian Bender, David T. W. Jones, Simone Mü… . - 14 S.
In: OncoTarget, ISSN 1949-2553. 7(2016), 38, S. 61860-61873
DOI: 10.18632/oncotarget.11452
- Gessi, Marco: Evidence of H3 K27M mutations in posterior fossa ependymomas / Marco Gessi, David Capper, Felix Sahm, Kristin Huang, Andreas von Deimling, Stephan Tippelt, Gudrun … . - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 132(2016), 4, S. 635-637
DOI: 10.1007/s00401-016-1608-3
- Bender, Sebastian: Recurrent MET fusion genes represent a drug target in pediatric glioblastoma / Sebastian Bender, Jan Gronych, Hans-Jörg Warnatz, Barbara Hutter, Susanne Gröbner, Marina Ryzhova, E… , 17 October 2016. - 9 S.
In: Nature medicine, ISSN 1546-170X. 22(2016), 11, Seite 1314-1322
DOI: 10.1038/nm.4204
- Rahmanto, Aldwin Suryo: FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma / Aldwin Suryo Rahmanto, Vasil Savov, Andrä Brunner, Sara Bolin, Holger Weishaupt, Alena Malyukova, Ga… , 13 September 2016. - 21 S.
In: The EMBO journal, ISSN 1460-2075. 35(2016), 20, Seite 2192-2212
DOI: 10.15252/embj.201693889
- Mangum, Ross Michael: SHH desmoplastic/nodular medulloblastoma and Gorlin syndrome in the setting of Down syndrome : case report, molecular profiling, and review of the literature / Ross Mangum, Elizabeth Varga, Daniel R. Boué, David Capper, Martin Benesch, Jeffrey Leonard, Diana S… . - 8 S.
In: Child's nervous system, ISSN 1433-0350. 32(2016), 12, S. 2439-2446
DOI: 10.1007/s00381-016-3185-0
- Bueren, André von: Treatment of children and adolescents with metastatic medulloblastoma and prognostic relevance of clinical and biologic parameters / André O. von Bueren, Rolf-Dieter Kortmann, Katja von Hoff, Carsten Friedrich, Martin Mynarek, Klaus … , October 3, 2016. - 10 S.
In: Journal of clinical oncology, ISSN 1527-7755. 34(2016), 34, Seite 4151-4160
DOI: 10.1200/JCO.2016.67.2428
- Vollmuth, Philipp: Radiogenomics of glioblastoma : machine learning-based classification of molecular characteristics by using multiparametric and multiregional MR imaging features / Philipp Kickingereder, David Bonekamp, Martha Nowosielski, Annekathrin Kratz, Martin Sill, Sina Burt… , 16 August 2016. - 12 S.
In: Radiology, ISSN 1527-1315. 281(2016), 3, Seite 907-918
DOI: 10.1148/radiol.2016161382
- Ecker, Jonas: Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma / Jonas Ecker, Ina Oehme, Ralph Mazitschek, Andrey Korshunov, Marcel Kool, Thomas Hielscher, Judit Kis… . -
London: BioMed Central, 2016. - 1 Online-Ressource (14 Seiten)
DOI: 10.1186/s40478-015-0201-7
- Fontebasso, Adam: Non-random aneuploidy specifies subgroups of pilocytic astrocytoma and correlates with older age / Adam M. Fontebasso, Margret Shirinian, Dong-Anh Khuong-Quang, Denise Bechet, Tenzin Gayden, Marcel K… , September 10, 2015. - 13 S.
In: OncoTarget, ISSN 1949-2553. 6(2015), 31, Seite 31844-31856
DOI: 10.18632/oncotarget.5571
- Pfister, Stefan: Schlussbericht zum CancerSys-Verbundprojekt „MYC-NET - Aufklärung der Mechanismen MYC-getriebener Therapieresistenz neuroectodermaler Tumore“ : Laufzeit des Vorhabens: 01.03.2012-28.02.2015 / Zuwendungsempfänger: Universitätsklinikum Heidelberg, Abteilung Pädiatrische Hämatologie und Onkolog… . -
Heidelberg: Universitätsklinikum Heidelberg, Abteilung Pädiatrische Hämatologie und Onkologie, 31.08.2015. - 1 Online-Ressource (14 Seiten, 657,76 KB) : Illustration
DOI: 10.2314/GBV:872584631
- Pfister, Stefan: Schlussbericht zum CancerSys-Verbundprojekt „MYC-NET - Aufklärung der Mechanismen MYC-getriebener Therapieresistenz neuroectodermaler Tumore“ : Laufzeit des Vorhabens: 01.03.2012-28.02.2015 / Zuwendungsempfänger: Universitätsklinikum Heidelberg, Abteilung Pädiatrische Hämatologie und Onkolog… . -
Heidelberg: Universitätsklinikum Heidelberg, Abteilung Pädiatrische Hämatologie und Onkologie, 31.08.2015. - 13 Blätter, 1 ungezähltes Blatt : Illustration
- Ozolek, John A.: Medulloepithelioma with peculiar clinical presentation, stem cell phenotype and aberrant DNA-methylation profile / John A Ozolek, Debra E Cohen, Marcel Kool, Stefan M Pfister, Andrey Korshunov, Andrew J Bukowinski &… , 29 Jun 2015. - 10 S.
In: CNS Oncology, ISSN 2045-0915. 4(2015), 4, Seite 203-212
DOI: 10.2217/cns.15.9
- Mack, Stephen C.: Spinal myxopapillary ependymomas demonstrate a warburg phenotype / Stephen C. Mack, Sameer Agnihotri, Kelsey C. Bertrand, Xin Wang, David J. Shih, Hendrik Witt, Nadia … , May 8, 2015. - 9 S.
In: Clinical cancer research, ISSN 1557-3265. 21(2015), 16, Seite 3750-3758
DOI: 10.1158/1078-0432.CCR-14-2650
- Korshunov, Andrey: Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity / Andrey Korshunov, David Capper, David Reuss, Daniel Schrimpf, Marina Ryzhova, Volker Hovestadt, Domi… , 2016. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 131(2016), 1, Seite 137-146
DOI: 10.1007/s00401-015-1493-1
- Herrlinger, Ulrich: Gliomatosis cerebri : no evidence for a separate brain tumor entity / Ulrich Herrlinger, David T.W. Jones, Martin Glas, Elke Hattingen, Dorothee Gramatzki, Moritz Stuplic… , 2016. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 131(2016), 2, Seite 309-319
DOI: 10.1007/s00401-015-1495-z
- Asti, Esterina D': Tissue factor regulation by miR-520g in primitive neuronal brain tumor cells : a possible link between oncomirs and the vascular tumor microenvironment / Esterina D'Asti, Annie Huang, Marcel Kool, Brian Meehan, Jennifer A. Chan, Nada Jabado, Andrey Korsh… , 2016. - 14 S.
In: The American journal of pathology, ISSN 1525-2191. 186(2016), 2, Seite 446-459
DOI: 10.1016/j.ajpath.2015.10.020
- Heim, Stephanie: Papillary tumor of the pineal region : a distinct molecular entity / Stephanie Heim, Martin Sill, David T.W. Jones, Alexandre Vasiljevic, Anne Jouvet, Michelle Fèvre‐Mon… , 2016. - 7 S.
In: Brain pathology, ISSN 1750-3639. 26(2016), 2, Seite 199-205
DOI: 10.1111/bpa.12282
- Sahm, Felix: Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets / Felix Sahm, Daniel Schrimpf, David T.W. Jones, Jochen Meyer, Annekathrin Kratz, David Reuss, David C… , 2016. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 131(2016), 6, Seite 903-910
DOI: 10.1007/s00401-015-1519-8
- Pajtler, Kristian Wilfried: Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups / Kristian W. Pajtler, Hendrik Witt, Martin Sill, David T.W. Jones, Volker Hovestadt, Fabian Kratochwi… , May 11, 2015. - 16 S.
In: Cancer cell, ISSN 1878-3686. 27(2015), 5, Seite 728-743
DOI: 10.1016/j.ccell.2015.04.002
- Buss, Meghan C.: The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants / Meghan C. Buss, Marc Remke, Juhyun Lee, Khanjan Gandhi, Matthew J. Schniederjan, Marcel Kool, Paul A… . - 15 S.
In: Oncogene, ISSN 1476-5594. 34(2015), 9, S. 1126-1140
DOI: 10.1038/onc.2014.37
- Korshunov, Andrey: Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers / Andrey Korshunov, Marina Ryzhova, Volker Hovestadt, Sebastian Bender, Dominik Sturm, David Capper, J… , 10 March 2015. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 129(2015), 5, Seite 669-678
DOI: 10.1007/s00401-015-1405-4
- Antonelli, Manila: Long-term survival in a case of ETANTR with histological features of neuronal maturation after therapy / Manila Antonelli, Andrey Korshunov, Angela Mastronuzzi, Francesca Diomedi Camassei, Andrea Carai, Gi… . - 5 S.
In: Virchows Archiv, ISSN 1432-2307. 466(2015), 5, S. 603-607
DOI: 10.1007/s00428-015-1736-5
- Goschzik, Tobias: Molecular stratification of medulloblastoma : comparison of histological and genetic methods to detect Wnt activated tumours / Tobias Goschzik, Anja Zur Mühlen, Glen Kristiansen, Christine Haberler, Harald Stefanits, Carsten Fr… . - 10 S.
In: Neuropathology & applied neurobiology, ISSN 1365-2990. 41(2015), 2, S. 135-144
DOI: 10.1111/nan.12161
- Northcott, Paul A.: Next-generation (epi)genetic drivers of childhood brain tumours and the outlook for targeted therapies / Paul A Northcott, Stefan M Pfister, David TW Jones, 27 May 2015. - 10 S.
In: The lancet, ISSN 1474-5488. 16(2015), 6, Seite e293-e302
DOI: 10.1016/S1470-2045(14)71206-9
- Jakobiec, Frederick A.: Intraocular medulloepitheliomas and embryonal tumors with multilayered rosettes of the brain : comparative roles of LIN28A and C19MC / Frederick A. Jakobiec, Marcel Kool, Anna M. Stagner, Stefan M. Pfister, Ralph C. Eagle, Alan D. Proi… , 5 March 2015. - 10 S.
In: American journal of ophthalmology, ISSN 1879-1891. 159(2015), 6, Seite 1065-1074.e1
DOI: 10.1016/j.ajo.2015.03.002
- Reuss, David: Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities / David E. Reuss, Annekathrin Kratz, Felix Sahm, David Capper, Daniel Schrimpf, Christian Koelsche, Vo… , September 2015. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 130(2015), 3, Seite 407-417
DOI: 10.1007/s00401-015-1454-8
- Wang, Xin: Medulloblastoma subgroups remain stable across primary and metastatic compartments / Xin Wang, Adrian M. Dubuc, Vijay Ramaswamy, Stephen Mack, Deena M.A. Gendoo, Marc Remke, Xiaochong W… . - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 129(2015), 3, S. 449-457
DOI: 10.1007/s00401-015-1389-0
- Reuss, David: ATRX and IDH1‑R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an “integrated” diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma / David E. Reuss, Felix Sahm, Daniel Schrimpf, Benedikt Wiestler, David Capper, Christian Koelsche, Le… , 2015. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 129(2015), 1, Seite 133-146
DOI: 10.1007/s00401-014-1370-3
- Korshunov, Andrey: Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities / Andrey Korshunov, Frederick A. Jakobiec, Charles G. Eberhart, Volker Hovestadt, David Capper, David … . - 7 S.
In: Neuropathology, ISSN 1440-1789. 35(2015), 6, S. 538-544
DOI: 10.1111/neup.12227
- Alioto, Tyler: A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing / Tyler S. Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D. Eldridge, Eivind Hovig, L…
In: Nature Communications, ISSN 2041-1723. 6(2015) Artikel-Nummer 10001, 13 Seiten
DOI: 10.1038/ncomms10001
- Geisenberger, Christoph: Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain / Christoph Geisenberger; Andreas Mock; Rolf Warta; Carmen Rapp; Christian Schwager; Andrey Korshunov;… , 2015. - 16 S.
In: Acta neuropathologica, ISSN 1432-0533. 130(2015), 3, Seite 419-434
DOI: 10.1007/s00401-015-1427-y
- Mack, Stephen C.: Epigenomic alterations define lethal CIMP-positive ependymomas of infancy / S.C. Mack, H. Witt, R.M. Piro, L. Gu, S. Zuyderduyn, A.M. Stütz, X. Wang, M. Gallo, L. Garzia, K. Za… , 19 February 2014. - 9 S.
In: Nature, ISSN 1476-4687. 506(2014), 7489, Seite 445-453
DOI: 10.1038/nature13108
- Jeibmann, Astrid: Identification of genes involved in the biology of atypical teratoid/rhabdoid tumours using Drosophila melanogaster / Astrid Jeibmann, Kristin Eikmeier, Anna Linge, Marcel Kool, Björn Koos, Jacqueline Schulz, Stefanie … , 3 Jun 2014. - 9 S. : Illustrationen
In: Nature Communications, ISSN 2041-1723. 5(2014) Artikel-Nummer 4005, 9 Seiten
DOI: 10.1038/ncomms5005
- Faria, Claudia C.: Foretinib is effective therapy for metastatic Sonic Hedgehog medulloblastoma / Claudia C. Faria, Brian J. Golbourn, Adrian M. Dubuc, Marc Remke, Roberto J. Diaz, Sameer Agnihotri,… , 2015. - 13 S.
In: Cancer research, ISSN 1538-7445. 75(2015), 1, Seite 134-146
DOI: 10.1158/0008-5472.CAN-13-3629
- Hutter, Sonja: Whole exome sequencing reveals that the majority of schwannomatosis cases remain unexplained after excluding SMARCB1 and LZTR1 germline variants / Sonja Hutter · Rosario M. Piro · David E. Reuss · Volker Hovestadt · Felix Sahm · Said Farschtschi ·… , 10 July 2014. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 3, Seite 449-452
DOI: 10.1007/s00401-014-1311-1
- Mille, Frédéric: The Shh receptor Boc promotes progression of early medulloblastoma to advanced tumors / Frédéric Mille, Lukas Tamayo-Orrego, Martin Lévesque, Marc Remke, Andrey Korshunov, Julie Cardin, Ni… , September 25, 2014. - 14 S.
In: Developmental cell, ISSN 1878-1551. 31(2014), 1, Seite 34-47
DOI: 10.1016/j.devcel.2014.08.010
- Milde, Till: Ependymoma / Till Milde, Andrey Korshunov, Olaf Witt, Stefan M. Pfister, Hendrik Witt, 2015. - 9 S.
In: Molecular Pathology of Nervous System Tumors. (2015), Seite 67-75
DOI: 10.1007/978-1-4939-1830-0_5
- Kölsche, Christian: Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles / Christian Koelsche; Volker Hovestadt; David T.W. Jones; David Capper; Dominik Sturm; Felix Sahm; Dan… , 2015. - 7 S.
In: Brain pathology, ISSN 1750-3639. 25(2015), 2, Seite 202-208
DOI: 10.1111/bpa.12228
- Batora, Nadja: Transitioning from genotypes to epigenotypes : why the time has come for medulloblastoma epigenomics / N.V. Batora, D. Sturm, D.T.W. Jones, M. Kool, S.M. Pfister, P.A. Northcott. - 15 S.
In: Neuroscience, ISSN 1873-7544. 264(2014), S. 171-185
DOI: 10.1016/j.neuroscience.2013.07.030
- Gronych, Jan: Connect four with glioblastoma stem cell factors / Jan Gronych, Stefan M. Pfister, David T.W. Jones, 24 April 2014. - 3 S.
In: Cell, ISSN 1097-4172. 157(2014), 3, Seite 525-527
DOI: 10.1016/j.cell.2014.04.001
- Wefers, Annika K.: Subgroup-specific localization of human medulloblastoma based on pre-operative MRI / Annika K. Wefers, Monika Warmuth-Metz, Julia Pöschl, André O. von Bueren, Camelia-Maria Monoranu, Kl… , 04 April 2014. - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 127(2014), 6, Seite 931-933
DOI: 10.1007/s00401-014-1271-5
- Othman, Ramadhan: Overcoming multiple drug resistance mechanisms in medulloblastoma / Ramadhan T. Othman,Ioanna Kimishi, Tracey D. Bradshaw, Lisa CD. Storer, Andrey Korshunov, Stefan M. … . -
London: BioMed Central, 2016. - 1 Online-Ressource (14 Seiten)
- Inta, Ioana: Guanine nucleotide-binding protein α subunit hypofunction in children with short stature and disproportionate shortening of the 4th and 5th metacarpals / Ioana Monica Inta, Daniela Choukair, Sebastian Bender, Carolin Kneppo, Sabine Knauer-Fischer, Kahina… , January 25, 2014. - 8 S.
In: Hormone research in paediatrics, ISSN 1663-2826. 81(2014), 3, Seite 196-203
DOI: 10.1159/000356928
- Hovestadt, Volker: Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing / Volker Hovestadt, David T.W. Jones, Simone Picelli, Wei Wang, Marcel Kool, Paul A. Northcott, Marc S… , 2014. - 5 S.
In: Nature, ISSN 1476-4687. 510(2014), 7506, Seite 537-541
DOI: 10.1038/nature13268
- Pöschl, Julia: Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts / Julia Pöschl, Sebastian Stark, Philipp Neumann, Susanne Gröbner, Daisuke Kawauchi, David T.W. Jones,… , July 2014. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 1, Seite 123-136
DOI: 10.1007/s00401-014-1297-8
- Vanner, Robert: Quiescent sox(2+) cells drive hierarchical growth and relapse in Sonic Hedgehog subgroup medulloblastoma / Robert J. Vanner, Marc Remke, Marco Gallo, Hayden J. Selvadurai, Fiona Coutinho, Lilian Lee, Michell… , 14 July 2014. - 15 S.
In: Cancer cell, ISSN 1878-3686. 26(2014), 1, Seite 33-47
DOI: 10.1016/j.ccr.2014.05.005
- Northcott, Paul A.: Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma / Paul A. Northcott, Catherine Lee, Thomas Zichner, Adrian M. Stütz, Serap Erkek, Daisuke Kawauchi, Da… , 24 July 2014. - 7 S.
In: Nature, ISSN 1476-4687. 511(2014), 7510, Seite 428-434
DOI: 10.1038/nature13379
- Rack, Paul Geroge: Arhgap36-dependent activation of Gli transcription factors / Paul G. Rack, Jun Ni, Alexander Y. Payumo, Vien Nguyen, J. Aaron Crapster, Volker Hovestadt, Marcel … , 29 July 2014. - 6 S.
In: Proceedings of the National Academy of Sciences of the United States of America, ISSN 1091-6490. 111(2014), 30, Seite 11061-11066
DOI: 10.1073/pnas.1322362111
- Korshunov, Andrey: Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity / Andrey Korshunov, Dominik Sturm, Marina Ryzhova, Volker Hovestadt, Marco Gessi, David T.W. Jones, Ma… . - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 2, S. 279-289
DOI: 10.1007/s00401-013-1228-0
- Moreno, Natalia: Loss of smarc proteins impairs cerebellar development / Natalia Moreno, Christin Schmidt, Julia Ahlfeld, Julia Pöschl, Stefanie Dittmar, Stefan M. Pfister, … . - 6 S.
In: The journal of neuroscience, ISSN 1529-2401. 34(2014), 40, S. 13486-13491
DOI: 10.1523/JNEUROSCI.2560-14.2014
- Karajannis, Matthias A.: Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas / Matthias A. Karajannis, Geneviève Legault, Michael J. Fisher, Sarah S. Milla, Kenneth J. Cohen, Jeff… . - 9 S.
In: Neuro-Oncology, ISSN 1523-5866. 16(2014), 10, S. 1408-1416
DOI: 10.1093/neuonc/nou059
- Kool, Marcel: Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition / Marcel Kool, David T.W. Jones, Natalie Jäger, Paul A. Northcott, Trevor J. Pugh, Volker Hovestadt, R… , 17 March 2014. - 13 S.
In: Cancer cell, ISSN 1878-3686. 25(2014), 3, Seite 393-405
DOI: 10.1016/j.ccr.2014.02.004
- Shih, David J. H.: Cytogenetic prognostication within medulloblastoma subgroups / David J.H. Shih, Paul A. Northcott, Marc Remke, Andrey Korshunov, Vijay Ramaswamy, Marcel Kool, Bett… . - 11 S.
In: Journal of clinical oncology, ISSN 1527-7755. 32(2014), 9, S. 886-896
DOI: 10.1200/JCO.2013.50.9539
- Pietsch, Torsten: Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort / Torsten Pietsch, Rene Schmidt, Marc Remke, Andrey Korshunov, Volker Hovestadt, David T.W. Jones, Jör… , 4 May 2014. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 1, Seite 137-149
DOI: 10.1007/s00401-014-1276-0
- Kölsche, Christian: Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour / Christian Koelsche, Leonille Schweizer, Marcus Renner, Arne Warth, David T. W. Jones, Felix Sahm, Da… , 2014. - 10 S.
In: Histopathology, ISSN 1365-2559. 65(2014), 5, Seite 613-622
DOI: 10.1111/his.12431
- Asti, Esterina D': Coagulation and angiogenic gene expression profiles are defined by molecular subgroups of medulloblastoma : evidence for growth factor-thrombin cross-talk / E. D'Asti, M. Kool, S. M. Pfister andJ. Rak. - 12 S.
In: Journal of thrombosis and haemostasis, ISSN 1538-7836. 12(2014), 11, S. 1838-1849
DOI: 10.1111/jth.12715
- Gajjar, Amar: Molecular insights into pediatric brain tumors have the potential to transform therapy / Amar Gajjar, Stefan M. Pfister, Michael D. Taylor, Richard J. Gilbertson. - 11 S.
In: Clinical cancer research, ISSN 1557-3265. 20(2014), 22, S. 5630-5640
DOI: 10.1158/1078-0432.CCR-14-0833
- Wiestler, Benedikt: Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial / Benedikt Wiestler, David Capper, Volker Hovestadt, Martin Sill, David T.W. Jones, Christian Hartmann… , 2014. - 9 S.
In: Neuro-Oncology, ISSN 1523-5866. 16(2014), 12, Seite 1630-1638
DOI: 10.1093/neuonc/nou138
- Wiestler, Benedikt: Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma / Benedikt Wiestler, David Capper, Martin Sill, David T. W. Jones, Volker Hovestadt, Dominik Sturm, Ch… , 2014. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 4, Seite 561-571
DOI: 10.1007/s00401-014-1315-x
- Sahm, Felix: Farewell to oligoastrocytoma : in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma / Felix Sahm, David Reuss, Christian Koelsche, David Capper, Jens Schittenhelm, Stephanie Heim, David … , 2014. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 128(2014), 4, Seite 551-559
DOI: 10.1007/s00401-014-1326-7
- Dreidax, Daniel: p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas / Daniel Dreidax, Steffen Bannert, Kai-Oliver Henrich, Christina Schröder, Sebastian Bender, Christoph… , 2014. - 12 S.
In: Human molecular genetics, ISSN 1460-2083. 23(2014), 25, Seite 6826-6837
DOI: 10.1093/hmg/ddu406
- Lacroix, Jeannine: Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis / Jeannine Lacroix, Franziska Schlund, Barbara Leuchs, Kathrin Adolph, Dominik Sturm, Sebastian Bender… , 2014. - 14 S.
In: International journal of cancer, ISSN 1097-0215. 134(2014), 3, Seite 703-716
DOI: 10.1002/ijc.28386
- Erdreich-Epstein, Anat: PID1 (NYGGF4), a new growth-inhibitory gene in embryonal brain tumors and gliomas / Erdreich-Epstein, Anat ... Jones, David T. W.; Pfister, Stefan M.; Kool, Marcel ..., 2014. - 10 S.
In: Clinical cancer research, ISSN 1557-3265. 20(2014), 4, Seite 827-836
DOI: 10.1158/1078-0432.CCR-13-2053
- Milla, Luis A.: Neogenin1 is a Sonic Hedgehog target in medulloblastoma and is necessary for cell cycle progression / Milla, Luis A.; Arros, Andrea; Espinoza, Natalie; Remke, Marc; Kool, Marcel; Taylor, Michael D.; Pfi… , 2014. - 11 S.
In: International journal of cancer, ISSN 1097-0215. 134(2014), 1, Seite 21-31
DOI: 10.1002/ijc.28330
- Sturm, Dominik: Paediatric and adult glioblastoma : multiform (epi)genomic culprits emerge / Dominik Sturm, Sebastian Bender, David T. W. Jones, Peter Lichter, Jacques Grill, Oren Becher, Cynth… , 2014. - 16 S.
In: Nature reviews, ISSN 1474-1768. 14(2014), 2, Seite 92-107
DOI: 10.1038/nrc3655
- Valdora, Francesca: Epigenetic silencing of DKK3 in medulloblastoma / Francesca Valdora, Barbara Banelli, Sara Stigliani, Stefan M. Pfister, Stefano Moretti, Marcel Kool,… , 8 April 2013. - 14 S.
In: International journal of molecular sciences, ISSN 1422-0067. 14(2013), 4, Seite 7492-7505
DOI: 10.3390/ijms14047492
- Fontebasso, Adam: Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas / Adam M. Fontebasso, Jeremy Schwartzentruber, Dong-Anh Khuong-Quang, Xiao-Yang Liu, Dominik Sturm, An… , 16 February 2013. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 5, Seite 659-669
DOI: 10.1007/s00401-013-1095-8
- Spina, Raffaella: Critical role of zinc finger protein 521 in the control of growth, clonogenicity and tumorigenic potential of medulloblastoma cells / Raffaella Spina, Gessica Filocamo, Enrico Iaccino, Stefania Scicchitano, Michela Lupia, Emanuela Chi… , 2013. - 13 S.
In: OncoTarget, ISSN 1949-2553. 4(2013), 8, Seite 1280-1292
DOI: 10.18632/oncotarget.1176
- Tönjes, Martje: BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1 / Martje Tönjes, Sebastian Barbus, Yoon Jung Park, Wei Wang, Magdalena Schlotter, Anders M. Lindroth, … , 23 June 2013. - 8 S.
In: Nature medicine, ISSN 1546-170X. 19(2013), 7, Seite 901-908
DOI: 10.1038/nm.3217
- Leprivier, Gabriel: The eEF2 kinase confers resistance to nutrient deprivation by blocking translation elongation / Gabriel Leprivier, Marc Remke, Barak Rotblat, Adrian Dubuc, Abigail-Rachele F. Mateo, Marcel Kool, S… , May 23, 2013. - 16 S.
In: Cell, ISSN 1097-4172. 153(2013), 5 vom: Mai, Seite 1064-1079
DOI: 10.1016/j.cell.2013.04.055
- Rieber, Nora: Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies / Nora Rieber, Marc Zapatka, Bärbel Lasitschka, David Jones, Paul Northcott, Barbara Hutter, Natalie J… , June 11, 2013. - 11 S.
In: PLOS ONE, ISSN 1932-6203. 8(2013), 6, Artikel-ID e66621, Seite 1-11
DOI: 10.1371/journal.pone.0066621
- Reuss, David: Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations / David E. Reuss, Rosario M. Piro, David T.W. Jones, Matthias Simon, Ralf Ketter, Marcel Kool, Albert … , 12 February 2013. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 351-358
DOI: 10.1007/s00401-013-1093-x
- Remke, Marc: TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma / Marc Remke, Vijay Ramaswamy, John Peacock, David J.H. Shih, Christian Koelsche, Paul A. Northcott, N… , 31 October 2013. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 6, Seite 917-929
DOI: 10.1007/s00401-013-1198-2
- Ramaswamy, Vijay: Recurrence patterns across medulloblastoma subgroups : an integrated clinical and molecular analysis / Vijay Ramaswamy, Marc Remke, Eric Bouffet, Claudia C Faria, Sebastien Perreault, Yoon-Jae Cho, David… , October 17, 2013. - 8 S.
In: The lancet, ISSN 1474-5488. 14(2013), 12 vom: Nov., Seite 1200-1207
DOI: 10.1016/S1470-2045(13)70449-2
- Plass, Christoph: Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer / Christoph Plass, Stefan M. Pfister, Anders M. Lindroth, Olga Bogatyrova, Rainer Claus and Peter Lich… , 9 October 2013. - 16 S.
In: Nature reviews, ISSN 1471-0064. 14(2013), 11, Seite 765-780
DOI: 10.1038/nrg3554
- Wiestler, Benedikt: ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis / Benedikt Wiestler, David Capper, Tim Holland-Letz, Andrey Korshunov, Andreas von Deimling, Stefan Mi… , 1 August 2013. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 3, Seite 443-451
DOI: 10.1007/s00401-013-1156-z
- Weller, Michael: Molecular neuro-oncology in clinical practice : a new horizon / Michael Weller, Stefan M Pfister, Wolfgang Wick, Monika E Hegi, Guido Reifenberger, Roger Stupp, 26 July 2013. - 10 S.
In: The lancet, ISSN 1474-5488. 14(2013), 9, Seite e370-e379
DOI: 10.1016/S1470-2045(13)70168-2
- Hovestadt, Volker: Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays / Volker Hovestadt, Marc Remke, Marcel Kool, Torsten Pietsch, Paul A. Northcott, Roger Fischer, Floren… , 14 May 2013. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 6, Seite 913-916
DOI: 10.1007/s00401-013-1126-5
- Lambert, Sally R.: Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma / Sally R. Lambert, Hendrik Witt, Volker Hovestadt, Manuela Zucknick, Marcel Kool, Danita M. Pearson, … , 10 May 2013. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 2 vom: Aug., Seite 291-301
DOI: 10.1007/s00401-013-1124-7
- Mack, Stephen C.: Emerging insights into the ependymoma epigenome / Stephen C. Mack, Hendrik Witt, Xin Wang, Till Milde, Yuan Yao, Kelsey C. Bertrand, Andrey Korshunov,… , 25 February 2013. - 4 S.
In: Brain pathology, ISSN 1750-3639. 23(2013), 2 vom: März, Seite 206-209
DOI: 10.1111/bpa.12020
- Alexandrov, Ludmil: Corrigendum : Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 9 October 2013. - 1 S.
In: Nature, ISSN 1476-4687. 502(2013), 7470, Seite 258-258
DOI: 10.1038/nature12666
- Alexandrov, Ludmil: Signatures of mutational processes in human cancer / Ludmil B. Alexandrov, Serena Nik-Zainal, David C. Wedge, Samuel A. J. R. Aparicio, Sam Behjati, Andr… , 14 August 2013. - 7 S.
In: Nature, ISSN 1476-4687. 500(2013), 7463, Seite 415-421
DOI: 10.1038/nature12477
- Jones, David T. W.: The role of chromatin remodeling in medulloblastoma / David T.W. Jones; Paul A. Northcott; Marcel Kool; Stefan M. Pfister, 25 February 2013. - 7 S.
In: Brain pathology, ISSN 1750-3639. 23(2013), 2 vom: März, Seite 193-199
DOI: 10.1111/bpa.12019
- Dykhuizen, Emily C.: BAF complexes facilitate decatenation of DNA by topoisomerase IIα / Emily C. Dykhuizen, Diana C. Hargreaves, Erik L. Miller, Kairong Cui, Andrey Korshunov, Marcel Kool,… , 22 May 2013. - 4 S.
In: Nature, ISSN 1476-4687. 497(2013), 7451, Seite 624-627
DOI: 10.1038/nature12146
- Dubuc, Adrian M.: Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma / Adrian M. Dubuc, Marc Remke, Andrey Korshunov, Paul A. Northcott, Shing H. Zhan, Maria Mendez-Lago, … , 2013. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 3, Seite 373-384
DOI: 10.1007/s00401-012-1070-9
- Bender, Sebastian: Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas / Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, David T.W. Jones, Marcel Kool, M… , October 31, 2013. - 13 S.
In: Cancer cell, ISSN 1878-3686. 24(2013), 5, Seite 660-672
DOI: 10.1016/j.ccr.2013.10.006
- Schweizer, Leonille: Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein / Leonille Schweizer · Christian Koelsche · Felix Sahm · Rosario M. Piro · David Capper · David E. Reu… , 2013. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 125(2013), 5, Seite 651-658
DOI: 10.1007/s00401-013-1117-6
- Sahm, Felix: AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry / Sahm, Felix; Bissel, Juliane; Koelsche, Christian; Schweizer, Leonille; Capper, David; Reuss, David;… , 2013. - 6 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 5, Seite 757-762
DOI: 10.1007/s00401-013-1187-5
- Kölsche, Christian: Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system / Koelsche, Christian; Sahm, Felix; Capper, David; Reuss, David ... Wiestler, Benedikt; Boehmer, Katja… , 2013. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 126(2013), 6, Seite 907-915
DOI: 10.1007/s00401-013-1195-5
- Jäger, Natalie: Hypermutation of the inactive X chromosome is a frequent event in cancer / Natalie Jäger ... Jan-Philipp Mallm ... Andrey Korshunov... Hendrik Witt ... Karsten Rippe ... Stefa… , 2013. - 15 S.
In: Cell, ISSN 1097-4172. 155(2013), Seite 1-15
DOI: 10.1016/j.cell.2013.09.042
- Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 2012. - 6 S.
In: Nature, ISSN 0028-0836. 488(2012), 7409 vom: 20. Juni, Seite 100-105
- Weeraratne, Shyamal Dilhan: Pleiotropic effects of miR-183~96~182 converge to regulate cell survival, proliferation and migration in medulloblastoma / Shyamal Dilhan Weeraratne, Vladimir Amani, Natalia Teider, Jessica Pierre-Francois, Dominic Winter, … , 10 March 2012. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 539-552
DOI: 10.1007/s00401-012-0969-5
- Dubuc, Adrian M.: Subgroup-specific alternative splicing in medulloblastoma / Adrian M. Dubuc, A. Sorana Morrissy, Nanne K. Kloosterhof, Paul A. Northcott, Emily P.Y. Yu, David S… , April 2012. - 15 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 485-499
DOI: 10.1007/s00401-012-0959-7
- Milde, Till: HD-MB03 is a novel Group 3 medulloblastoma model demonstrating sensitivity to histone deacetylase inhibitor treatment / Till Milde, Marco Lodrini, Larissa Savelyeva, Andrey Korshunov, Marcel Kool, Lena M. Brueckner, Andr… , December 2012. - 14 S.
In: Journal of neuro-oncology, ISSN 1573-7373. 110(2012), 3, Seite 335-348
DOI: 10.1007/s11060-012-0978-1
- Milde, Till: Nestin expression identifies ependymoma patients with poor outcome / Till Milde, Thomas Hielscher, Hendrik Witt, Marcel Kool, Stephen C. Mack, Hedwig E. Deubzer, Ina Oeh… , 09 May 2012. - 13 S.
In: Brain pathology, ISSN 1750-3639. 22(2012), 6, Seite 848-860
DOI: 10.1111/j.1750-3639.2012.00600.x
- Pugh, Trevor: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations / Trevor J. Pugh, Shyamal Dilhan Weeraratne, Tenley C. Archer, Daniel A. Pomeranz Krummel, Daniel Aucl… , 22 July 2012. - 5 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 106-110
DOI: 10.1038/nature11329
- Pfister, Stefan: Medulloblastoma : a potpourri of distinct entities / Stefan Pfister, 7 March 2012. - 2 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 463-464
DOI: 10.1007/s00401-012-0966-8
- Picard, Daniel: Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours : an integrative genomic analysis / Daniel Picard, Suzanne Miller, Cynthia E Hawkins, Eric Bouffet, Hazel A Rogers, Tiffany SY Chan, Seu… , August 2012. - 11 S.
In: The lancet, ISSN 1474-5488. 13(2012), 8, Seite 838-848
DOI: 10.1016/S1470-2045(12)70257-7
- Korshunov, Andrey: LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) / Andrey Korshunov, Marina Ryzhova, David T. W. Jones, Paul A. Northcott, Peter van Sluis, Richard Vol… , 16 November 2012. - 7 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 6, Seite 875-881
DOI: 10.1007/s00401-012-1068-3
- Korshunov, Andrey: Biological and clinical heterogeneity of MYCN-amplified medulloblastoma / Andrey Korshunov, Marc Remke, Marcel Kool, Thomas Hielscher, Paul A. Northcott, Dan Williamson, Elke… , 2012. - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 515-527
DOI: 10.1007/s00401-011-0918-8
- Kool, Marcel: Molecular subgroups of medulloblastoma : an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas / Marcel Kool, Andrey Korshunov, Marc Remke, David T.W. Jones, Maria Schlanstein, Paul A. Northcott, Y… , 23 February 2012. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 473-484
DOI: 10.1007/s00401-012-0958-8
- Liu, Xiao-Yang: Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations / Xiao-Yang Liu, Noha Gerges, Andrey Korshunov, Nesrin Sabha, Dong-Anh Khuong-Quang, Adam M. Fontebass… , 12 August 2012. - 11 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 5, Seite 615-625
DOI: 10.1007/s00401-012-1031-3
- Wu, Xiaochong: Clonal selection drives genetic divergence of metastatic medulloblastoma / Xiaochong Wu, Paul A. Northcott, Adrian Dubuc, Adam J. Dupuy, David J.H. Shih, Hendrik Witt, Sidney … , 23 February 2012. - 5 S.
In: Nature, ISSN 1476-4687. 482(2012), 7386, Seite 529-533
DOI: 10.1038/nature10825
- Vo, Dat T.: The RNA-binding protein musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis / Dat T. Vo, Dharmalingam Subramaniam, Marc Remke, Tarea L. Burton, Philip J. Uren, Jonathan A. Gelfon… , 14 September 2012. - 11 S. : Illustrationen
In: The American journal of pathology, ISSN 1525-2191. 181(2012), 5, Seite 1762-1772
DOI: 10.1016/j.ajpath.2012.07.031
- Bai, Alfa H. C.: MicroRNA-182 promotes leptomeningeal spread of non-Sonic Hedgehog-medulloblastoma / Alfa H. C. Bai, Till Milde, Marc Remke, Claudio G. Rolli, Thomas Hielscher, Yoon-Jae Cho, Marcel Koo… , 2012. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 529-538
DOI: 10.1007/s00401-011-0924-x
- Northcott, Paul A.: Medulloblastomics : the end of the beginning / Paul A. Northcott, David T.W. Jones, Marcel Kool, Giles W. Robinson, Richard J. Gilbertson, Yoon-Jae… , 23 November 2012. - 17 S.
In: Nature reviews, ISSN 1474-1768. 12(2012), 12, Seite 818-834
DOI: 10.1038/nrc3410
- Northcott, Paul A.: Molecular subgroups of medulloblastoma / Paul A. Northcott, Adrian M. Dubuc, Stefan Pfister, Michael D. Taylor. - 14 S.
In: Expert review of neurotherapeutics, ISSN 1744-8360. 12(2012), 7, S. 871-884
DOI: 10.1586/ern.12.66
- Witt, Hendrik: Molecular approaches to ependymoma : the next step(s) / Hendrik Witt, Andrey Korshunov, Stefan M. Pfister, and Till Milde, 2012. - 6 S.
In: Current opinion in neurology, ISSN 1473-6551. 25(2012), 6, Seite 745-750
DOI: 10.1097/WCO.0b013e328359cdf5
- Jones, David T. W.: Dissecting the genomic complexity underlying medulloblastoma / David T.W. Jones, Natalie Jäger, Marcel Kool, Thomas Zichner, Barbara Hutter, Marc Sultan, Yoon-Jae … , 25 July 2012. - 6 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, Seite 100-105
DOI: 10.1038/nature11284
- Guldal, Cemile G.: An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation / Cemile G. Guldal, Adiba Ahmad, Andrey Korshunov, Massimo Squatrito, Aashir Awan, Lori A. Mainwaring,… , 3 February 2012. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 573-586
DOI: 10.1007/s00401-012-0946-z
- Khuong-Quang, Dong-Anh: K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas / Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos, Xiao-Yang Liu, Adam M. Fontebasso, Eri… , 3 June 2012. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 124(2012), 3, Seite 439-447
DOI: 10.1007/s00401-012-0998-0
- Bueren, André von: DNA copy number alterations in central primitive neuroectodermal tumors and tumors of the pineal region : an international individual patient data meta-analysis / André O. von Bueren, Joachim Gerss, Christian Hagel, Haoyang Cai, Marc Remke, Martin Hasselblatt, Bu… , 7 July 2012. - 9 S. : Illustrationen
In: Journal of neuro-oncology, ISSN 1573-7373. 109(2012), 2, Seite 415-423
DOI: 10.1007/s11060-012-0911-7
- Pei, Yanxin: An animal model of MYC-driven medulloblastoma / Yanxin Pei, Colin E. Moore, Jun Wang, Alok K. Tewari, Alexey Eroshkin, Yoon-Jae Cho, Hendrik Witt, A… , February 13, 2012. - 13 S.
In: Cancer cell, ISSN 1878-3686. 21(2012), 2, Seite 155-167
DOI: 10.1016/j.ccr.2011.12.021
- Northcott, Paul A.: Subgroup-specific structural variation across 1000 medulloblastoma genomes / Paul A. Northcott, David J. H. Shih, John Peacock, Livia Garzia, A. Sorana Morrissy, Thomas Zichner,… . - 8 S.
In: Nature, ISSN 1476-4687. 488(2012), 7409, S. 49-56
DOI: 10.1038/nature11327
- Schwartzentruber, Jeremy: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma / Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu, David T.W. Jones, Elke Pfaff, Karine Jacob… , 29 January 2012. - 6 S.
In: Nature, ISSN 1476-4687. 482(2012), 7384, Seite 226-231
DOI: 10.1038/nature10833
- Grammel, Daniel: Sonic Hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem / Daniel Grammel, Monika Warmuth-Metz, André O. von Bueren, Marcel Kool, Torsten Pietsch, Hans A. Kret… , 21 February 2012. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 601-614
DOI: 10.1007/s00401-012-0961-0
- Rausch, Tobias: Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations / Tobias Rausch, David T.W. Jones, Marc Zapatka, Adrian M. Stütz, Thomas Zichner, Joachim Weischenfeld… , 19 January 2012. - 13 S.
In: Cell, ISSN 1097-4172. 148(2012), 1, Seite 59-71
DOI: 10.1016/j.cell.2011.12.013
- Northcott, Paul A.: Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples / Paul A. Northcott, David J.H. Shih, Marc Remke, Yoon-Jae Cho, Marcel Kool, Cynthia Hawkins, Charles … , April 2012. - 12 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 615-626
DOI: 10.1007/s00401-011-0899-7
- Sturm, Dominik: Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma / Dominik Sturm; Hendrik Witt ... David T. W. Jones; Carolin Konermann; Elke Pfaff ... Sebastian Bende… , October 15, 2012. - 13 S.
In: Cancer cell, ISSN 1878-3686. 22(2012), 4, Seite 425-437
DOI: 10.1016/j.ccr.2012.08.024
- Gessi, Marco: Absence of chromosome 19q13.41 amplification in a case of atypical teratoid/rhabdoid tumor with ependymoblastic differentiation / Marco Gessi, Stefan Pfister, Volkmar H. Hans, Andrey Korshunov, Torsten Pietsch, 2011. - 3 S.
In: Acta neuropathologica, ISSN 1432-0533. 121(2011), 2 vom: Feb., Seite 283-285
DOI: 10.1007/s00401-010-0778-7
- Pfaff, Elke: Reply to J.C. Lindsey et al / Elke Pfaff, Marc Remke, Dominik Sturm, Axel Benner, Hendrik Witt, Till Milde, André O. von Bueren, N… , February 28, 2011. - 2 S.
In: Journal of clinical oncology, ISSN 1527-7755. 29(2011), 12, Seite e348-e349
DOI: 10.1200/JCO.2010.34.1545
- Woehrer, Adelheid: Embryonal tumor with abundant neuropil and true rosettes (ETANTR) with loss of morphological but retained genetic key features during progression / Adelheid Woehrer, Irene Slavc, Andreas Peyrl, Thomas Czech, Christian Dorfer, Daniela Prayer, Susann… , 6 November 2011. - 4 S.
In: Acta neuropathologica, ISSN 1432-0533. 122(2011), 6, Seite 787-790
DOI: 10.1007/s00401-011-0903-2
- Witt, Hendrik: Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma / Hendrik Witt, Stephen C. Mack, Marina Ryzhova, Sebastian Bender, Martin Sill, Ruth Isserlin, Axel Be… , August 15, 2011. - 15 S.
In: Cancer cell, ISSN 1878-3686. 20(2011), 2, Seite 143-157
DOI: 10.1016/j.ccr.2011.07.007
- Ening, Genevieve: Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma / Genevieve Schindler, David Capper, Jochen Meyer, Wibke Janzarik, Heymut Omran, Christel Herold-Mende… , 29 January 2011. - 9 S.
In: Acta neuropathologica, ISSN 1432-0533. 121(2011), 3, Seite 397-405
DOI: 10.1007/s00401-011-0802-6
- Northcott, Paul A.: Medulloblastoma comprises four distinct molecular variants / Paul A. Northcott, Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Charles G. Eberhart, Stephen Ma… , 2011. - 7 S.
In: Journal of clinical oncology, ISSN 1527-7755. 29(2011), 11, Seite 1408-1414
DOI: 10.1200/JCO.2009.27.4324
- Northcott, Paul A.: Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct / Paul A. Northcott, Thomas Hielscher, Adrian Dubuc, Stephen Mack, David Shih, Marc Remke, Hani Al-Hal… , 17 June 2011. - 10 S.
In: Acta neuropathologica, ISSN 1432-0533. 122(2011), 2, Seite 231-240
DOI: 10.1007/s00401-011-0846-7
- Remke, Marc: Adult medulloblastoma momprises three major molecular variants / Marc Remke, Thomas Hielscher, Paul A. Northcott, Hendrik Witt, Marina Ryzhova, Andrea Wittmann, Axel… , May 31, 2011. - 7 S.
In: Journal of clinical oncology, ISSN 1527-7755. 29(2011), 19, Seite 2717-2723
DOI: 10.1200/JCO.2011.34.9373
- Remke, Marc: FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma / Marc Remke, Thomas Hielscher, Andrey Korshunov, Paul A. Northcott, Sebastian Bender, Marcel Kool, Fr… , September 12, 2011. - 10 S.
In: Journal of clinical oncology, ISSN 1527-7755. 29(2011), 29, Seite 3852-3861
DOI: 10.1200/JCO.2011.36.2798
- Miller, Suzanne: Genome-wide molecular characterization of central nervous system primitive neuroectodermal tumor and pineoblastoma / Suzanne Miller, Hazel A. Rogers, Paul Lyon, Vikki Rand, Martyna Adamowicz-Brice, Steven C. Clifford,… , 20 July 2011. - 14 S.
In: Neuro-Oncology, ISSN 1523-5866. 13(2011), 8, Seite 866-879
DOI: 10.1093/neuonc/nor070
- Milde, Till: A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat / Till Milde, Susanne Kleber, Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Philipp Koch, Hans-Geo… , 24 August 2011. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 122(2011), 5, Artikel-ID 637, Seite 1-14
DOI: 10.1007/s00401-011-0866-3
- Gronych, Jan: An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice / Jan Gronych, Andrey Korshunov, Josephine Bageritz, Till Milde, Manfred Jugold, Dolores Hambardzumyan… , April 2011. - 5 S.
In: The journal of clinical investigation, ISSN 1558-8238. 121(2011), 4, Seite 1344-1348
DOI: 10.1172/JCI44656
- Jacob, Karine: Genetic aberrations leading to MAPK pathway activation mediate oncogene-induced senescence in sporadic pilocytic astrocytomas / Karine Jacob, Dongh-Anh Quang-Khuong, David T.W. Jones, Hendrik Witt, Sally Lambert, Steffen Albrech… , July 17 2011. - 11 S.
In: Clinical cancer research, ISSN 1557-3265. 17(2011), 14, Seite 4650-4660
DOI: 10.1158/1078-0432.CCR-11-0127
- Eisenhardt, Anja: Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma / Anja E. Eisenhardt, Heike Olbrich, Michael Röring, Wibke Janzarik, Ton Nu Van Anh, Huriye Cin, Marc … , 2011. - 7 S.
In: International journal of cancer, ISSN 1097-0215. 129(2011), 9, Seite 2297-2303
DOI: 10.1002/ijc.25893
- Bertrand, Kelsey C.: PCDH10 is a candidate tumour suppressor gene in medulloblastoma / Kelsey C. Bertrand, Stephen C. Mack, Paul A. Northcott, Livia Garzia, Adrian Dubuc, Stefan M. Pfiste… , 20 May 2011. - 7 S.
In: Child's nervous system, ISSN 1433-0350. 27(2011), 8, Seite 1243-1249
DOI: 10.1007/s00381-011-1486-x
- Jones, David T. W.: MAPK pathway activation in pilocytic astrocytoma / David T.W. Jones, Jan Gronych, Peter Lichter, Olaf Witt, Stefan M. Pfister, 2012. - 13 S.
In: Cellular and molecular life sciences, ISSN 1420-9071. 69(2012), 11, Seite 1799-1811
DOI: 10.1007/s00018-011-0898-9
- Taylor, Michael D.: Molecular subgroups of medulloblastoma : the current consensus / Michael D. Taylor, Paul A. Northcott, Andrey Korshunov, Marc Remke, Yoon-Jae Cho, Steven C. Clifford… , 2012. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, Seite 465-472
DOI: 10.1007/s00401-011-0922-z
- Ryan, Sarra: MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma / Sarra L. Ryan, Ed C. Schwalbe, Michael Cole, Yuan Lu, Meryl E. Lusher, Hisham Megahed, Kieran O’Tool… . - 13 S.
In: Acta neuropathologica, ISSN 1432-0533. 123(2012), 4, S. 501-513
DOI: 10.1007/s00401-011-0923-y
- Tränka, Christopher: Role of LIM and SH3 Protein 1 (LASP1) in the Metastatic Dissemination of Medulloblastoma / Christopher Traenka, Marc Remke, Andrey Korshunov, Sebastian Bender, Thomas Hielscher, Paul A. North… , October 13 2010. - 12 S.
In: Cancer research, ISSN 1538-7445. 70(2010), 20, Seite 8003-8014
DOI: 10.1158/0008-5472.CAN-10-0592
- International Cancer Genome Consortium: International network of cancer genome projects / The International Cancer Genome Consortium, 15 April 2010. - 6 S.
In: Nature, ISSN 1476-4687. 464(2010), 7291, Seite 993-998
DOI: 10.1038/nature08987
- Pfister, Stefan: Molecular diagnostics of CNS embryonal tumors / Stefan M. Pfister, Andrey Korshunov, Marcel Kool, Martin Hasselblatt, Charles Eberhart, Michael D. T… , 30 September 2010. - 14 S.
In: Acta neuropathologica, ISSN 1432-0533. 120(2010), 5 vom: Sept., Seite 553-566
DOI: 10.1007/s00401-010-0751-5
- Pfaff, Elke: TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma / Elke Pfaff, Marc Remke, Dominik Sturm, Axel Benner, Hendrik Witt, Till Milde, André O. von Bueren, A… , November 08, 2010. - 9 S.
In: Journal of clinical oncology, ISSN 1527-7755. 28(2010), 35 vom: Nov., Seite 5188-5196
DOI: 10.1200/JCO.2010.31.1670
- Milde, Till: HDAC5 and HDAC9 in medulloblastoma : novel markers for risk stratification and role in tumor cell growth / Till Milde, Ina Oehme, Andrey Korshunov, Annette Kopp-Schneider, Marc Remke, Paul Northcott, Hedwig … , June 14 2010. - 13 S.
In: Clinical cancer research, ISSN 1557-3265. 16(2010), 12, Seite 3240-3252
DOI: 10.1158/1078-0432.CCR-10-0395
- Korshunov, Andrey: Molecular staging of intracranial ependymoma in children and adults / Andrey Korshunov, Hendrik Witt, Thomas Hielscher, Axel Benner, Marc Remke, Marina Ryzhova, Till Mild… , June 1, 2010. - 9 S.
In: Journal of clinical oncology, ISSN 1527-7755. 28(2010), 19 vom: Juli, Seite 3182-3190
DOI: 10.1200/JCO.2009.27.3359
- Korshunov, Andrey: Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification / Andrey Korshunov, Marc Remke, Wiebke Werft, Axel Benner, Marina Ryzhova, Hendrik Witt, Dominik Sturm… , May 17, 2010. - 7 S.
In: Journal of clinical oncology, ISSN 1527-7755. 28(2010), 18 vom: Juni, Seite 3054-3060
DOI: 10.1200/JCO.2009.25.7121
- Korshunov, Andrey: Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes / Andrey Korshunov, Marc Remke, Marco Gessi, Marina Ryzhova, Thomas Hielscher, Hendrik Witt, Vivienne … , 21 April 2010. - 8 S.
In: Acta neuropathologica, ISSN 1432-0533. 120(2010), 2, Seite 253-260
DOI: 10.1007/s00401-010-0688-8
- Holzwarth, Christina: Low physiologic oxygen tensions reduce proliferation and differentiation of human multipotent mesenchymal stromal cells / Christina Holzwarth, Martin Vaegler, Friederike Gieseke, Stefan M. Pfister, Rupert Handgretinger, Gu… , 28 January 2010. - 11 S. : Illustrationen, Diagramme
In: BMC cell biology, ISSN 1471-2121. 11(2010) vom: Jan., Artikel-ID 11, Seite 1-11
DOI: 10.1186/1471-2121-11-11
- Dubuc, Adrian M.: The genetics of pediatric brain tumors / Adrian M. Dubuc, Paul A. Northcott, Stephen Mack, Hendrik Witt, Stefan Pfister, Michael D. Taylor, 12 March 2010. - 9 S.
In: Current neurology and neuroscience reports, ISSN 1534-6293. 10(2010), 3, Seite 215-223
DOI: 10.1007/s11910-010-0103-9
- Bork, Simone: DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells / Simone Bork, Stefan Pfister, Hendrik Witt, Patrick Horn, Bernhard Korn, Anthony D. Ho and Wolfgang W… , 11 January 2010. - 10 S.
In: Aging cell, ISSN 1474-9726. 9(2010), 1 vom: Feb., Seite 54-63
DOI: 10.1111/j.1474-9726.2009.00535.x
- Pfister, Stefan: Genomic profiling identifies novel prognostic biomarkers and signalling pathways for targeted therapies in childhood brain tumors / vorgelegt von Stefan Michael Pfister, 2010. - Getr. Zählung : Ill., graph. Darst.
- Pfister, Stefan: Regulation und Funktion von Mitgliedern der TNFalpha-Familie bei Doxorubicin-induzierter Apoptose und bei einem Patienten mit einem lymphoproliferativen Syndrom / Stefan Pfister, 2002. - Online-Ressource
